Abstract:
:7 alpha- and 7 beta-carboxymethyl-derivatives of 17-hydroxyprogesterone and 11-deoxycortisol have been synthesized. After coupling to bovine serum albumin, they were used to elicit antibodies in rabbits. No major difference in the steroid specificity of the antisera was observed when either 7 alpha- or 7 beta-epimers were used for immunization. In both cases, highly specific antisera were obtained which may possibly be used to assay human plasma 17-hydroxyprogesterone and 11-deoxycortisol without chromatographic purification.
journal_name
Steroidsjournal_title
Steroidsauthors
Duval D,Prédine J,Emiliozzi R,Milgrom Edoi
10.1016/0039-128x(80)90112-9subject
Has Abstractpub_date
1980-01-01 00:00:00pages
65-80issue
1eissn
0039-128Xissn
1878-5867pii
0039-128X(80)90112-9journal_volume
35pub_type
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