Dacryoadenoma. A unique tumor of the conjunctival epithelium.

Abstract:

:For 15 years, a 48-year-old woman had been aware of a pinkish translucent inferior epibulbar mass toward the fornix that was stationary in size. Light microscopic evaluation of the excised specimen showed that it was a gland-forming benign tumor. It originated from the surface epithelium by the downward invagination of tubular formations that underwent secondary and tertiary ramifications. The surface epithelium overlying the mass was not normal conjunctival squamous epithelium, but it was a modification in the form of a superficial layer of columnar to cuboidal cells surmounting several nuclei similar to the cells lining the subepithelial lumen-forming units. Electron microscopy showed that both the surface and tumor epithelium contained apical lacrimal-type zymogen granules and basilar whorls of rough-surfaced endoplasmic reticulum. Scattered myoepithelial cells were associated with the acinar-type epithelium of the tumor, and there were goblet cells intermixed. Neither light nor electron microscopy disclosed the presence of true ducts. The authors conclude that the lesion was a benign proliferation of lacrimal secretory-type cells and suggest the term "dacryoadenoma" for this previously undescribed entity.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Jakobiec FA,Perry HD,Harrison W,Krebs W

doi

10.1016/s0161-6420(89)32799-0

subject

Has Abstract

pub_date

1989-07-01 00:00:00

pages

1014-20

issue

7

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(89)32799-0

journal_volume

96

pub_type

杂志文章
  • Optic Nerve Length before and after Spaceflight.

    abstract:PURPOSE:The spaceflight-associated neuro-ocular syndrome (SANS) affects astronauts on missions to the International Space Station (ISS). The SANS has blurred vision and ocular changes as typical features. The objective of this study was to investigate if microgravity can create deformations or movements of the eye or o...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2020.07.007

    authors: Wåhlin A,Holmlund P,Fellows AM,Malm J,Buckey JC,Eklund A

    更新日期:2021-02-01 00:00:00

  • The effect of dorzolamide on aqueous humor dynamics in normal human subjects during sleep.

    abstract:OBJECTIVE:The purpose of the study was to measure the effect of the topical carbonic anhydrase inhibitor, 2% dorzolamide hydrochloride, on the rate of aqueous humor flow in sleeping humans. DESIGN:A randomized, double-masked, placebo-controlled study. PARTICIPANTS:Twenty-five normal human subjects. INTERVENTION:Topi...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/S0161-6420(98)98043-5

    authors: Vanlandingham BD,Maus TL,Brubaker RF

    更新日期:1998-08-01 00:00:00

  • The axial length/disc area ratio in anisometropic hyperopic amblyopia: a hypothesis for decreased unilateral vision associated with hyperopic anisometropia.

    abstract:OBJECTIVE:Hyperopic anisometropia is a risk factor for amblyopia. Disc areas and axial lengths are reduced in amblyopic eyes. This study's aim was to investigate the differences in the relative size of the optic disc in 5 groups of eyes: (1) normal right eyes; (2) smaller eyes of nonamblyopic, anisometropic, bilateral ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2003.05.020

    authors: Lempert P

    更新日期:2004-02-01 00:00:00

  • Incidence of visual impairment over a 20-year period: the Beaver Dam Eye Study.

    abstract:PURPOSE:To describe visual impairment (VI) over a 20-year period and its associations with age-related eye diseases and socioeconomic factors in the Beaver Dam Eye Study. DESIGN:Population-based cohort study. PARTICIPANTS:Four thousand nine hundred twenty-six persons 43 to 86 years of age participated in the baseline...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2012.11.041

    authors: Klein R,Lee KE,Gangnon RE,Klein BE

    更新日期:2013-06-01 00:00:00

  • Progression of scleral disease.

    abstract::The clinical features of 290 patients with scleral inflammation were reviewed to determine whether a classification based on the anatomical site and clinical appearance of the disease at presentation reflected its natural history. The authors' results confirm that the majority of patients remain in the same clinical c...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(91)32269-3

    authors: Tuft SJ,Watson PG

    更新日期:1991-04-01 00:00:00

  • Sector-based analysis with the Heidelberg Retinal Tomograph 3 across disc sizes and glaucoma stages: a multicenter study.

    abstract:PURPOSE:To investigate the ability of sectorial analysis using the Heidelberg Retinal Tomograph 3 (HRT3) to discriminate between healthy and glaucomatous eyes and to determine whether this is affected by disc size and glaucoma severity. DESIGN:Multicenter, cross-sectional evaluation of diagnostic tests. PARTICIPANTS:...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ophtha.2009.01.020

    authors: Oddone F,Centofanti M,Iester M,Rossetti L,Fogagnolo P,Michelessi M,Capris E,Manni G

    更新日期:2009-06-01 00:00:00

  • Nonmechanical excimer laser penetrating keratoplasty for perforated or predescemetal corneal ulcers.

    abstract:OBJECTIVE:To review the authors' results using nonmechanical excimer laser trephination in penetrating keratoplasty for perforated or predescemetal corneal ulcers. DESIGN:Noncomparative, consecutive, interventional case series. PARTICIPANTS:Thirty-two patients with perforated (17) or deep (15) corneal ulcers (9 bacte...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/S0161-6420(99)90506-7

    authors: Küchle M,Seitz B,Langenbucher A,Naumann GO

    更新日期:1999-11-01 00:00:00

  • Long-term surgical outcomes of patients with glaucoma secondary to the iridocorneal endothelial syndrome.

    abstract:PURPOSE:To report the long-term outcomes of patients with iridocorneal endothelial (ICE) syndrome who required surgery for glaucoma. DESIGN:Retrospective, noncomparative case series. PARTICIPANTS:Twenty-six patients with ICE syndrome who underwent surgery for glaucoma at one institution between January 1987 and Janua...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(01)00725-4

    authors: Doe EA,Budenz DL,Gedde SJ,Imami NR

    更新日期:2001-10-01 00:00:00

  • A randomized, dose-escalation study of subconjunctival and intravitreal injections of sirolimus in patients with diabetic macular edema.

    abstract:OBJECTIVE:To evaluate the safety and tolerability of a single subconjunctival (SCJ) or intravitreal (IVT) injection of an ophthalmic sirolimus formulation in eyes with diabetic macular edema (DME). DESIGN:Randomized, open-label, dose-escalating phase I study. PARTICIPANTS:Fifty eyes among 50 patients with DME, retina...

    journal_title:Ophthalmology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.ophtha.2011.07.034

    authors: Dugel PU,Blumenkranz MS,Haller JA,Williams GA,Solley WA,Kleinman DM,Naor J

    更新日期:2012-01-01 00:00:00

  • Amyloidosis of corneal stroma in patients with trachoma. A clinicopathologic study of 62 cases.

    abstract::Sixty-two cases of corneal amyloidosis were studied. The median age of the 48 men and 14 women was 66 years. The patients had bilateral, diffuse corneal opacity extending to the limbus and severe visual impairment. The corneal condition was not familial. Advanced stages of trachoma were present in all individuals. Cli...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(89)32765-5

    authors: Hidayat AA,Risco JM

    更新日期:1989-08-01 00:00:00

  • Associations between health-related quality of life and the decision to perform surgery for childhood intermittent exotropia.

    abstract:OBJECTIVE:To assess associations between health-related quality of life (HRQOL) and the decision to perform strabismus surgery for children with intermittent exotropia. DESIGN:Retrospective chart review. PARTICIPANTS:Children with intermittent exotropia. METHODS:Included subjects, identified in a clinical practice, ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2013.10.029

    authors: Hatt SR,Leske DA,Liebermann L,Mohney BG,Brodsky MC,Yamada T,Holmes JM

    更新日期:2014-04-01 00:00:00

  • Proton beam irradiation. An alternative to enucleation for intraocular melanomas.

    abstract::Proton irradiation was used in the treatment of uveal melanomas in 36 eyes. The average follow-up period was 16 months. One patient developed metastatic disease and died. No eye has been enucleated and tumor regression has been observed in all 22 eyes with a follow-up of more than 12 months. This type of treatment off...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(80)35212-3

    authors: Gragoudas ES,Goitein M,Verhey L,Munzenreider J,Suit HD,Koehler A

    更新日期:1980-06-01 00:00:00

  • Associations of the C2-CFB-RDBP-SKIV2L locus with age-related macular degeneration and polypoidal choroidal vasculopathy.

    abstract:PURPOSE:To investigate the associations of the C2-CFB-RDBP-SKIV2L region with neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). DESIGN:Cross-sectional, case-control association study. PARTICIPANTS:A Chinese case-control group of 200 neovascular AMD patients, 233 PCV patie...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2012.10.003

    authors: Liu K,Chen LJ,Tam PO,Shi Y,Lai TY,Liu DT,Chiang SW,Yang M,Yang Z,Pang CP

    更新日期:2013-04-01 00:00:00

  • Superior oblique tenectomy in Brown's syndrome.

    abstract::Since its description in 1950, numerous surgical techniques have been advocated to treat Brown's superior oblique tendon sheath syndrome. Of these, a tenectomy of the homolateral superior oblique has emerged as the most effective method. However, an iatrogenically produced superior oblique paralysis has been found to ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(82)34787-9

    authors: von Noorden GK,Olivier P

    更新日期:1982-04-01 00:00:00

  • Comparison of depth of focus and low-contrast acuities for monofocal versus multifocal intraocular lens patients at 1 year.

    abstract:PURPOSE:Multifocal lenses have been shown to produce enhanced near and intermediate vision. The division of incoming light into more than one focal point must physically produce retinal images of reduced contrast. The purpose of this report is to provide quantitative data on the increased depth of focus and decreased c...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(92)31735-x

    authors: Post CT Jr

    更新日期:1992-11-01 00:00:00

  • Modified corncrib (inverted T) procedure with Quickert suture for repair of involutional entropion.

    abstract:PURPOSE:The purpose of the study was to determine long-term results of involutional entropion repair by a modified corncrib (inverted T) procedure with a Quickert suture. METHODS:A retrospective review of consecutive patients with involutional entropion who underwent repair by a modified corncrib procedure from Januar...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(97)30284-x

    authors: Mauriello JA,Abdelsalam A

    更新日期:1997-03-01 00:00:00

  • Effect of hinged lamellar keratotomy on postkeratoplasty eyes.

    abstract:PURPOSE:To evaluate the effect of a hinged lamellar keratotomy on refraction, vision, and corneal topography of postkeratoplasty eyes with high-degree astigmatism. DESIGN:Noncomparative, interventional case series. PARTICIPANTS:A hinged lamellar keratotomy was performed on nine eyes of nine patients at least 9 months...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(01)00702-3

    authors: Busin M,Arffa RC,Zambianchi L,Lamberti G,Sebastiani A

    更新日期:2001-10-01 00:00:00

  • Surgical management and outcomes of dislocated intraocular lenses.

    abstract:OBJECTIVE:To evaluate the surgical management and visual acuity outcomes in a large series of patients with dislocated intraocular lenses (IOLs). DESIGN:Retrospective consecutive noncomparative case series. PARTICIPANTS:All patients who underwent surgical management of dislocated IOLs by two vitreoretinal surgeons at...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(99)00017-2

    authors: Mello MO Jr,Scott IU,Smiddy WE,Flynn HW,Feuer W

    更新日期:2000-01-01 00:00:00

  • Pseudophakic flat anterior chamber following retinal detachment repair.

    abstract::Flat anterior chambers were caused by varying mechanisms in 10 of 70 consecutive pseudophakic eyes operated on for retinal detachment. With iris or capsular implant fixation, three of 46 (7%) developed flat anterior chambers, and with anterior chamber lenses, the occurrence was seven of 24 (29%). Events initiating fla...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(81)80008-5

    authors: Taylor BC,Winslow RL

    更新日期:1981-09-01 00:00:00

  • Three-dimensional measurements of idiopathic macular holes using a scanning laser tomograph.

    abstract:PURPOSE:The diagnosis of macular holes is difficult. Confocal laser tomographic analysis of the retina permits the precise measurements of the macular surface. The authors used this technique to study the macular area of patients with full-thickness macular holes. The purposes of these studies is to perform three-dimen...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(95)30847-0

    authors: Weinberger D,Stiebel H,Gaton DD,Priel E,Yassur Y

    更新日期:1995-10-01 00:00:00

  • Punctal occlusion for the dry eye. Three-year revision. American Academy of Ophthalmology.

    abstract::The purpose of the Committee on Ophthalmic Procedure Assessments is to evaluate on a scientific basis new and existing ophthalmic tests, devices, and procedures for their safety, efficacy, clinical effectiveness, and appropriate uses. Evaluations include examination of available literature, epidemiological analyses wh...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:

    authors:

    更新日期:1997-09-01 00:00:00

  • The role of adjunctive mitomycin C in secondary glaucoma triple procedure as compared to primary glaucoma triple procedure.

    abstract:OBJECTIVE:This study aimed to investigate whether previously failed glaucoma filtration surgery is a risk factor for filtration failure of subsequent trabeculectomy combined with cataract surgery and to determine the role of adjunctive mitomycin C (MMC) in the secondary glaucoma triple procedure (SGTP) as compared to p...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/S0161-6420(98)94032-5

    authors: Shin DH,Kim YY,Sheth N,Ren J,Shah M,Kim C,Yang KJ

    更新日期:1998-04-01 00:00:00

  • Adjunctive glaucoma therapy. A comparison of apraclonidine to dipivefrin when added to timolol maleate.

    abstract::The authors compared the additive intraocular pressure (IOP)-lowering effects of two different topical medications, apraclonidine hydrochloride and dipivefrin hydrochloride, when used in conjunction with timolol maleate. Eighteen patients with elevated IOPs entered a randomized, double-masked, cross-over study. Each u...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0161-6420(89)32977-0

    authors: Morrison JC,Robin AL

    更新日期:1989-01-01 00:00:00

  • Scheduled versus Pro Re Nata Dosing in the VIEW Trials.

    abstract:PURPOSE:To analyze visual acuity (VA) outcomes before and after preplanned treatment regimen change in the VIEW studies at week 52 (W52). DESIGN:Multiple post hoc analyses for retrospectively defined subgroups in 2 multicenter, multinational, double-masked trials. PARTICIPANTS:Two thousand four hundred fifty-seven ne...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.ophtha.2015.08.014

    authors: Richard G,Monés J,Wolf S,Korobelnik JF,Guymer R,Goldstein M,Norenberg C,Sandbrink R,Zeitz O

    更新日期:2015-12-01 00:00:00

  • Displacement of the optic nerve head by acute changes in intraocular pressure in monkey eyes.

    abstract::The authors used the Humphrey Retinal Analyzer to study the effect of acute changes in intraocular pressure (IOP) on the topography of the optic nerve head in normotensive and hypertensive eyes of cynomolgus monkeys. Chronically elevated IOP was produced monocularly in monkeys by argon laser angle treatment. In 8 hype...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(91)32345-5

    authors: Coleman AL,Quigley HA,Vitale S,Dunkelberger G

    更新日期:1991-01-01 00:00:00

  • Eyelid involvement in multicentric reticulohistiocytosis.

    abstract:CASE REPORT:The authors report the first biopsy-confirmed ocular adnexal involvement by multicentric reticulohistiocytosis. The patient was a 28-year-old black woman with a 15-year history of well-documented multicentric reticulohistiocytosis who had multiple dermal nodules and severe mutilating arthritis that had prod...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(95)31005-6

    authors: Eagle RC Jr,Penne RA,Hneleski IS Jr

    更新日期:1995-03-01 00:00:00

  • Suprachoroidal hemorrhage in pars plana vitrectomy: risk factors and outcomes over 10 years.

    abstract:PURPOSE:To investigate the rate and risk factors of developing suprachoroidal hemorrhage (SCH) after pars plana vitrectomy (PPV) and the outcomes as a result. DESIGN:Retrospective, comparative consecutive series. PARTICIPANTS:A total of 5459 patients who underwent pars plana vitrectomies over 10 years in 3 surgical c...

    journal_title:Ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.ophtha.2013.06.021

    authors: Chandra A,Xing W,Kadhim MR,Williamson TH

    更新日期:2014-01-01 00:00:00

  • The relation of cardiovascular disease and its risk factors to the 5-year incidence of age-related maculopathy: the Beaver Dam Eye Study.

    abstract:OBJECTIVE:The purpose of the study is to examine the association between cardiovascular disease and its risk factors and the incidence of age-related maculopathy. PARTICIPANTS:A population of 3583 adults (range, 43-86 years of age at baseline) living in Beaver Dam, Wisconsin, was studied at baseline and 5 years later....

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(97)30023-2

    authors: Klein R,Klein BE,Jensen SC

    更新日期:1997-11-01 00:00:00

  • Second nonocular tumors in retinoblastoma survivors. Are they radiation-induced?

    abstract::A review of 693 patients with bilateral retinoblastoma and 18 patients with unilateral/germinal retinoblastoma was carried out to find the incidence, time, course and pattern of second nonocular tumors in retinoblastoma survivors. Of 688 patients who survived therapeutic radiation for retinoblastoma, 89 developed seco...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(84)34127-6

    authors: Abramson DH,Ellsworth RM,Kitchin FD,Tung G

    更新日期:1984-11-01 00:00:00

  • Some factors governing the efficacy of positional pseudoaccommodative intraocular lenses.

    abstract:PURPOSE:To examine the effects of ametropia (spherocylindrical), corneal curvature, target anterior chamber depth (ACD), misplacement, and some design features on the performance of positional pseudoaccommodative intraocular lenses (PPAIOLs). DESIGN:Theoretical investigation based on computer models to determine the p...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2005.04.033

    authors: Alió JL,Patel S

    更新日期:2005-11-01 00:00:00