Abstract:
PURPOSE:Multifocal lenses have been shown to produce enhanced near and intermediate vision. The division of incoming light into more than one focal point must physically produce retinal images of reduced contrast. The purpose of this report is to provide quantitative data on the increased depth of focus and decreased contrast sensitivity demonstrated in patients receiving the 3M diffractive multifocal lens versus the parent monofocal control lens. METHODS:Uncorrected and best-corrected distance and near acuities, Regan and Pelli-Robson contrast sensitivity measurements, and defocus curves were obtained on 22 eyes with monofocal and 16 eyes with multifocal age-matched, pathology-free implants at 1 year after surgery. FINDINGS:Visual acuity data demonstrated significantly improved (P < 0.001) near acuities in multifocal patients with manifest refraction in place. No difference was noted between implants for other acuity measures. A statistically significant reduction (P < 0.05) in contrast sensitivity was measured for multifocal implants at the limits of contrast and resolution (Regan 4%); however, careful patient questioning revealed no clinical impact. Defocus curves demonstrated significantly increased (P < 0.0001) depth of focus at the 20/40 acuity level of 3.8 diopters (D) in multifocal patients versus 1.8 D in monofocal patients. CONCLUSION:The quantifiable and expected loss of contrast sensitivity in the examining lane, not manifest in patient awareness, appears to be an acceptable tradeoff for enhanced near/intermediate vision and depth of focus.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Post CT Jrdoi
10.1016/s0161-6420(92)31735-xsubject
Has Abstractpub_date
1992-11-01 00:00:00pages
1658-63; discussion 1663-4issue
11eissn
0161-6420issn
1549-4713pii
S0161-6420(92)31735-Xjournal_volume
99pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract::The blue field entoptic technique was used to study autoregulation of the macular retinal circulation in response to acute alterations of intraocular pressure in 71 diabetic eyes and 30 normals matched for age, systemic blood pressure, and ophthalmic artery diastolic pressure. IOPmax, the maximal intraocular pressure ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(82)34720-x
更新日期:1982-07-01 00:00:00
abstract:OBJECTIVE:To report endothelial cell densities (ECDs) and their correlation to anterior chamber depth (ACD) after implantation of the Artisan intraocular phakic lens. DESIGN:Prospective observational case series. PARTICIPANTS:Three hundred eighteen eyes of 173 myopic patients treated with the Artisan iris-fixated pha...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2007.05.036
更新日期:2008-04-01 00:00:00
abstract::Testing with the Cochet-Bonnet esthesiometer revealed a strong correlation between corneal sensitivity and retinal status in a group of diabetic patients. Eyes with normal fundi had normal corneal sensitivity. Those with background retinopathy had somewhat poliferative retinopathyl showed a greater loss of sensitivity...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(80)35257-3
更新日期:1980-03-01 00:00:00
abstract:PURPOSE:To evaluate two indices generated from measurements obtained from the Orbscan Corneal Topography System (CTS; Orbscan, Inc., Salt Lake City, UT) to distinguish contact lens-induced corneal thinning from keratoconus. The corneal thickness index (CTI) was used to compare central and peripheral corneal thicknesses...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(02)01276-9
更新日期:2002-12-01 00:00:00
abstract:PURPOSE:To investigate the associations of genetic variants in the high-density lipoprotein (HDL) metabolism pathway with neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). DESIGN:Cross-sectional, case-control association study. PARTICIPANTS:A Chinese case-control group of...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2013.10.042
更新日期:2014-04-01 00:00:00
abstract:PURPOSE:To investigate the associations of the C2-CFB-RDBP-SKIV2L region with neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). DESIGN:Cross-sectional, case-control association study. PARTICIPANTS:A Chinese case-control group of 200 neovascular AMD patients, 233 PCV patie...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.10.003
更新日期:2013-04-01 00:00:00
abstract::Fine needle aspiration biopsy (FNAB) of orbital tumors has been recently advocated as a reliable diagnostic modality. An accuracy rate of 92% has been claimed by some authors. This figure remains unproven as most patients have not undergone simultaneous pathologic examination. We recently performed FNAB on 34 patients...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(85)33984-2
更新日期:1985-05-01 00:00:00
abstract::Intraocular lenses have been regulated by the Bureau of Devices of the Food and Drug Administration since February 9, 1978. One year ago, data were reported through August 9, 1979, at which time more than 177,000 lenses of four different classes had been implanted. In the meantime, appeals and legal action by the Publ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(81)35014-3
更新日期:1981-05-01 00:00:00
abstract:PURPOSE:This article presents three patients with endophthalmitis associated with infection with Capnocytophaga species. METHODS:The medical records of three patients with culture-positive Capnocytophaga endophthalmitis were reviewed. A panel of isolates of Capnocytophaga were then tested for sensitivity to third-gene...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(93)31622-2
更新日期:1993-04-01 00:00:00
abstract:PURPOSE:To provide an initial assessment of the safety of a recombinant adeno-associated virus vector expressing RPE65 (rAAV2-CB-hRPE65) in adults and children with retinal degeneration caused by RPE65 mutations. DESIGN:Nonrandomized, multicenter clinical trial. PARTICIPANTS:Eight adults and 4 children, 6 to 39 years...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.ophtha.2016.03.003
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:To analyze the variability of clinical and electrophysiological characteristics in X-linked choroideremia and provide the first report of a negative electroretinogram in choroideremia. DESIGN:Retrospective study. PARTICIPANTS:The records of 18 male patients with choroideremia and 8 female carriers were evalua...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2006.05.045
更新日期:2006-11-01 00:00:00
abstract::The authors analyzed the clinical and follow-up data on 277 selected patients with primary choroidal or ciliochoroidal melanoma who were treated with 60Co plaque radiotherapy between 1976 and 1982. Local recurrence of the irradiated melanoma developed in 39 (14%) patients during the follow-up interval. The 5-year tumo...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(89)32882-x
更新日期:1989-03-01 00:00:00
abstract:PURPOSE:This is a pilot study to assess the use of autologous plasmin enzyme (APE) as an adjunct to vitreous surgery in eyes with advanced diabetic retinopathy. DESIGN:Prospective noncomparative interventional case series. PARTICIPANTS:Seven patients with advanced diabetic retinopathy selected at random from our prac...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/s0161-6420(01)00720-5
更新日期:2001-10-01 00:00:00
abstract::The accurate clinical diagnosis of benign mixed tumors of the lacrimal gland is imperative for proper therapeutic management. Although benign mixed tumors of the orbital portion of the lacrimal gland have an established identity, those tumors arising in the palpebral lobe are unusual. Four patients with benign mixed t...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(90)32572-1
更新日期:1990-04-01 00:00:00
abstract:PURPOSE:As of December 31, 2000, the neodymium:yttrium-aluminum-garnet (Nd:YAG) laser posterior capsulotomy rate for the Alcon AcrySof intraocular lens (IOL) as measured in our database was 3.3%. This was the lowest of any IOL model used in the United States. Only 12 of 361 cases required treatment. We analyzed possibl...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(02)01116-8
更新日期:2002-08-01 00:00:00
abstract::Retrobulbar hemorrhage associated with retrobulbar anesthesia has been construed as a contraindication to cataract surgery. Cancellation of the surgery results in disappointment for both the patient and surgeon. A retrospective study of 60 eyes was undertaken to evaluate the safety of proceeding with small-incision ph...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(91)32158-4
更新日期:1991-08-01 00:00:00
abstract::Autosomal dominant vitreoretinochoroidopathy (ADVIRC), a recently described disease, is clinically characterized by a slowly progressive or stationary circumferential peripheral pigmentary retinopathy with fibrillar condensation of the vitreous. Histopathologic study of an 88-year-old patient with this disease showed ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(89)32663-7
更新日期:1989-12-01 00:00:00
abstract:OBJECTIVE:The purpose of the study was to demonstrate that the arteriovenous shunt at the arteriovenous crossing could occur in major retinal vascular diseases other than Takayasu disease. DESIGN:Clinical review of consecutive case series. PARTICIPANTS:The authors studied 1885 eyes with retinal vascular diseases such...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(98)97030-0
更新日期:1998-07-01 00:00:00
abstract:PURPOSE:To characterize the clinicopathologic phenotype as well as the molecular genetic basis of an autosomal dominant form of corneal amyloidosis. DESIGN:Clinicopathologic and molecular genetic study of a family with a form of corneal amyloidosis. PARTICIPANTS:Forty-nine individuals from one family were studied. M...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2003.09.043
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVE:To determine whether glaucoma patients with progressive optic disc change have subsequent visual field progression earlier and at a faster rate compared with those without disc change. DESIGN:Prospective, longitudinal, cohort study. PARTICIPANTS AND CONTROLS:Eighty-one patients with open-angle glaucoma. ME...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2009.04.031
更新日期:2009-11-01 00:00:00
abstract::Thirteen patients complained of recent fluctuating aching of one orbit, punctuated by stabbing pains. All had exquisite point tenderness over the trochlea and in half of the patients the pain was aggravated by eye movement. Standardized A-scan echography demonstrated swelling of the peritrochlear tissue and thickening...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(84)34198-7
更新日期:1984-09-01 00:00:00
abstract:PURPOSE:To determine the heritability of nuclear cataract progression and to explore prospectively the effect of dietary micronutrients on the progression of nuclear cataract. DESIGN:Prospective cohort study. PARTICIPANTS:Cross-sectional nuclear cataract and dietary measurements were available for 2054 white female t...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2016.01.036
更新日期:2016-06-01 00:00:00
abstract::The use of the specular microscope as a noninvasive in vivo method of identifying cholesterol crystals in two cases of crystalline corneal deposits is described. This illustrates the advantage of using the specular microscope under living conditions with a much higher magnification than is obtained with the slit lamp....
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(88)33149-0
更新日期:1988-04-01 00:00:00
abstract:PURPOSE:To report the 24-month anatomic and Early Treatment Diabetic Retinopathy Study (ETDRS) best-corrected visual acuity (BCVA) response after primary intravitreal bevacizumab (Avastin; Genentech, Inc., San Francisco, CA; 1.25 or 2.5 mg) in patients with diffuse diabetic macular edema (DDME). In addition, a comparis...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2009.03.016
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:This study aimed to provide a comparative analysis of American population-based prevalence of uncorrected binocular distance visual acuity in Hispanics and non-Hispanics. DESIGN:The study design was a population-based survey. PARTICIPANTS:Data from the Hispanic Health and Nutrition Examination Survey betwee...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(98)93042-1
更新日期:1998-03-01 00:00:00
abstract:PURPOSE:To understand the impact of deep learning diabetic retinopathy (DR) algorithms on physician readers in computer-assisted settings. DESIGN:Evaluation of diagnostic technology. PARTICIPANTS:One thousand seven hundred ninety-six retinal fundus images from 1612 diabetic patients. METHODS:Ten ophthalmologists (5 ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2018.11.016
更新日期:2019-04-01 00:00:00
abstract::Recent studies have suggested that diffuse field loss and localized visual field loss in glaucomatous patients may have different pathophysiologic mechanisms. Testing that hypothesis requires that some patients present with purely localized field loss and other patients with purely diffuse loss. This article describes...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(91)32092-x
更新日期:1991-10-01 00:00:00
abstract:PURPOSE:To study size and contractility of the normal inferior oblique (IO) muscle using high-resolution magnetic resonance imaging (MRI) and to evaluate abnormalities of the superior oblique (SO) and IO muscles in chronic SO palsy. DESIGN:Prospective, case control study. PARTICIPANTS:Thirteen patients with SO palsy ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(03)00331-2
更新日期:2003-06-01 00:00:00
abstract:PURPOSE:To learn whether dilating the pupil will have an impact on glare testing for cataract evaluation. DESIGN:Evaluation of diagnostic test. PARTICIPANTS:Fifty-four adult patients at the Jones Eye Institute at the University of Arkansas for Medical Sciences. METHODS:One eye of each patient was randomized for stud...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2009.01.043
更新日期:2009-07-01 00:00:00
abstract:OBJECTIVE:To determine if glaucoma is associated with driving limitation or cessation. DESIGN:Cross-sectional analysis within a longitudinal, population-based cohort study. PARTICIPANTS AND CONTROLS:One thousand one hundred thirty-five ever-drivers between 73 and 93, including 70 subjects with unilateral and 68 subje...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2009.03.033
更新日期:2009-10-01 00:00:00