Abstract:
:The authors analyzed the clinical and follow-up data on 277 selected patients with primary choroidal or ciliochoroidal melanoma who were treated with 60Co plaque radiotherapy between 1976 and 1982. Local recurrence of the irradiated melanoma developed in 39 (14%) patients during the follow-up interval. The 5-year tumor recurrence rate (Kaplan-Meier) was estimated to be 12%. Multivariate prognostic factor analysis (Cox proportional hazards modeling) identified the largest linear tumor dimension and proximity of the posterior margin of the tumor to the optic nerve head as predictors of recurrence. The 5-year survival rate of patients whose tumors recurred (58%) was significantly (log-rank test P = 0.0023) worse than that of patients whose tumor remained clinically controlled (82%).
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Karlsson UL,Augsburger JJ,Shields JA,Markoe AM,Brady LW,Woodleigh Rdoi
10.1016/s0161-6420(89)32882-xsubject
Has Abstractpub_date
1989-03-01 00:00:00pages
382-8issue
3eissn
0161-6420issn
1549-4713pii
S0161-6420(89)32882-Xjournal_volume
96pub_type
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