The axial length/disc area ratio in anisometropic hyperopic amblyopia: a hypothesis for decreased unilateral vision associated with hyperopic anisometropia.

Abstract:

OBJECTIVE:Hyperopic anisometropia is a risk factor for amblyopia. Disc areas and axial lengths are reduced in amblyopic eyes. This study's aim was to investigate the differences in the relative size of the optic disc in 5 groups of eyes: (1) normal right eyes; (2) smaller eyes of nonamblyopic, anisometropic, bilateral hyperopes; (3) larger eyes of nonamblyopic, anisometropic, bilateral hyperopes; (4) fellow (nonamblyopic) eyes of eyes of amblyopic, anisometropic, bilateral hyperopes; and (5) amblyopic eyes of bilateral hyperopic anisometropes. To determine the relative size of the discs, the relationships of axial length to disc area in the above groups were evaluated. DESIGN:Case-control study. PARTICIPANTS:Nine hundred twenty-seven records from the author's private practice, which included axial length measurements and optic disc photographs or digital images, were analyzed to form the 5 groups above. METHODS:Disc areas were measured using objective techniques developed by Bengtsson and Krakau. Axial lengths were determined by ultrasound biometry or with a Zeiss IOL Master. MAIN OUTCOME MEASURES:Optic disc areas, corrected for magnification, axial lengths, and a derived ratio, axial length/disc area (AXL/DA). RESULTS:The AXL/DA for the amblyopic eyes (group 5) was significantly greater than that of all of the other groups, indicating that amblyopic eyes have discs that are both absolutely smaller and, when adjusted for eyes' size, relatively smaller than those of nonamblyopic eyes. CONCLUSION:The relatively small size of the discs of amblyopic eyes points to an organic as opposed to a functional amblyopia in these patients.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Lempert P

doi

10.1016/j.ophtha.2003.05.020

subject

Has Abstract

pub_date

2004-02-01 00:00:00

pages

304-8

issue

2

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(03)01163-1

journal_volume

111

pub_type

杂志文章
  • Pneumatic retinopexy. A multicenter randomized controlled clinical trial comparing pneumatic retinopexy with scleral buckling. The Retinal Detachment Study Group.

    abstract::Pneumatic retinopexy was compared with scleral buckling in a multicenter (7 centers), randomized, controlled, clinical trial with 198 patients. Admission criteria included detachments with retinal break(s) no greater than 1 clock hour in size, within the superior two thirds of the fundus, without significant prolifera...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0161-6420(89)32820-x

    authors: Tornambe PE,Hilton GF

    更新日期:1989-06-01 00:00:00

  • Orbital infections in patients with human immunodeficiency virus infection.

    abstract:BACKGROUND:Opportunistic infections frequently involve the anterior and posterior segments of the eye but rarely occur in the orbit in patients with human immunodeficiency virus (HIV) infection. The authors managed eight patients with HIV and unilateral orbital infections who presented between July 1988 and March 1995....

    journal_title:Ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1016/s0161-6420(96)30479-x

    authors: Kronish JW,Johnson TE,Gilberg SM,Corrent GF,McLeish WM,Scott KR

    更新日期:1996-09-01 00:00:00

  • Anterior chamber angle imaging with swept-source optical coherence tomography: measuring peripheral anterior synechia in glaucoma.

    abstract:OBJECTIVE:To investigate the use of swept-source optical coherence tomography (OCT) for measuring the area and degree of peripheral anterior synechia (PAS) involvement in patients with angle-closure glaucoma. DESIGN:Cross-sectional study. PARTICIPANTS:Twenty-three eyes with PAS (detected by indentation gonioscopy) fr...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2012.12.006

    authors: Lai I,Mak H,Lai G,Yu M,Lam DS,Leung CK

    更新日期:2013-06-01 00:00:00

  • Incidence and rates of visual field progression after longitudinally measured optic disc change in glaucoma.

    abstract:OBJECTIVE:To determine whether glaucoma patients with progressive optic disc change have subsequent visual field progression earlier and at a faster rate compared with those without disc change. DESIGN:Prospective, longitudinal, cohort study. PARTICIPANTS AND CONTROLS:Eighty-one patients with open-angle glaucoma. ME...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2009.04.031

    authors: Chauhan BC,Nicolela MT,Artes PH

    更新日期:2009-11-01 00:00:00

  • Comparison of Sulfur Hexafluoride 20% versus Air Tamponade in Descemet Membrane Endothelial Keratoplasty.

    abstract:PURPOSE:To compare clinical outcomes using 20% sulfur hexafluoride (SF6) versus 100% air as a tamponade for graft attachment in Descemet membrane endothelial keratoplasty (DMEK). DESIGN:Retrospective, comparative, interventional case series. PARTICIPANTS:Pseudophakic patients with Fuchs' endothelial dystrophy or pseu...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2015.05.013

    authors: Güell JL,Morral M,Gris O,Elies D,Manero F

    更新日期:2015-09-01 00:00:00

  • Efficacy of laser punctal occlusion.

    abstract::Dry eye is a common problem and in its more severe form may be treated with punctal occlusion. Photothermal coagulation of the puncta with the argon laser has recently been advocated to occlude the lacrimal puncta. Its long-term efficacy has not been investigated. The authors examined 22 puncta that had been occluded ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(92)31928-1

    authors: Benson DR,Hemmady PB,Snyder RW

    更新日期:1992-04-01 00:00:00

  • Long-term surgical outcomes of patients with glaucoma secondary to the iridocorneal endothelial syndrome.

    abstract:PURPOSE:To report the long-term outcomes of patients with iridocorneal endothelial (ICE) syndrome who required surgery for glaucoma. DESIGN:Retrospective, noncomparative case series. PARTICIPANTS:Twenty-six patients with ICE syndrome who underwent surgery for glaucoma at one institution between January 1987 and Janua...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(01)00725-4

    authors: Doe EA,Budenz DL,Gedde SJ,Imami NR

    更新日期:2001-10-01 00:00:00

  • Dipivefrin reduces blood flow in the ciliary body in humans.

    abstract:PURPOSE:Adrenergic substances are used widely for lowering intraocular pressure in the treatment of glaucoma. The hypothetic mechanisms for lowering the intraocular pressure by adrenergic drugs are decreased blood flow in the ciliary body and direct receptor-related reduction of aqueous humor production. The aim of thi...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0161-6420(94)31281-4

    authors: Michelson G,Groh MJ

    更新日期:1994-04-01 00:00:00

  • Pentacam assessment of posterior lamellar grafts to explain hyperopization after Descemet's stripping automated endothelial keratoplasty.

    abstract:PURPOSE:To evaluate changes in posterior corneal curvature as a possible cause of the hyperopic refractive shift observed after Descemet's stripping automated endothelial keratoplasty (DSAEK). DESIGN:Prospective, noncomparative, interventional case series. PARTICIPANTS:Thirty-four eyes of 29 patients with Fuchs' endo...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2009.04.035

    authors: Scorcia V,Matteoni S,Scorcia GB,Scorcia G,Busin M

    更新日期:2009-09-01 00:00:00

  • Augmented recession of the medial recti.

    abstract::Bimedial rectus recession with measurement from the limbus was combined with conjuctival recession 85 children undergoing surgery for esotropia. Using this augmented recession technique, the prism diopters of correction per millimeter of surgery done were 4.8 compared with 3.2 found in 56 control patients. Postoperati...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(78)35647-5

    authors: Helveston EM,Ellis FD,Patterson JH,Weber J

    更新日期:1978-05-01 00:00:00

  • Ocular presentation of polyarteritis nodosa. Clinical course and management with steroid and cytotoxic therapy.

    abstract:BACKGROUND:Polyarteritis nodosa is a necrotizing vasculitis affecting medium and small-sized arteries throughout the body, including ocular tissues. Untreated polyarteritis nodosa carries a very poor prognosis. Treatment with steroids increases the 5-year survival to 48%, whereas addition of cytotoxic immunosuppressive...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(93)31405-3

    authors: Akova YA,Jabbur NS,Foster CS

    更新日期:1993-12-01 00:00:00

  • Iridocorneal endothelial syndrome with contralateral guttate endothelial dystrophy. A light and electron microscopic study.

    abstract::Both eyes from a 75-year-old woman who had unilateral closed-angle glaucoma, characteristic endothelial specular microscopic findings, and slowly progressive tractional iris abnormalities consistent with essential iris atrophy were obtained postmortem and studied by light, scanning, and transmission electron microscop...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(87)33541-9

    authors: Eagle RC Jr,Shields JA

    更新日期:1987-07-01 00:00:00

  • Follow-up study of presumed ocular histoplasmosis syndrome.

    abstract::One hundred and sixty-two patients with presumed ocular histoplasmosis syndrome were evaluated. New macular scars not present on initial angiogram developed in 9% of eyes. The risk of developing a symptomatic macular lesion in eyes with asymptomatic macular scars was 23%. In eyes with peripapillary scarring, 3.8% deve...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(80)35226-3

    authors: Lewis ML,Van Newkirk MR,Gass JD

    更新日期:1980-05-01 00:00:00

  • B- and T-lymphocytes in ocular disease.

    abstract::Ocular inflammatory diseases and ocular adnexal lymphoid tumors have become less obscure and intimidating by virtue of our ability to study the infiltrates in these various diseases for their B-lymphocyte and T-lymphocyte composition. Comparisons are also possible between lymphocytic profiles in the peripheral blood a...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(84)34256-7

    authors: Jakobiec FA,Lefkowitch J,Knowles DM 2nd

    更新日期:1984-06-01 00:00:00

  • Lower eyelid retractors in Caucasians.

    abstract:PURPOSE:To examine the microscopic anatomic features of lower eyelid retractors in Caucasians, specifically looking for an anatomic division of the retractors into 2 layers, as is present in the Asian eyelid. DESIGN:Experimental anatomic study. PARTICIPANTS:Seven Caucasian cadavers (13 lower eyelids: 7 right and 6 le...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2009.01.031

    authors: Kakizaki H,Chan W,Madge SN,Malhotra R,Selva D

    更新日期:2009-07-01 00:00:00

  • Vertical diplopia and ptosis from removal of the orbital roof in pterional craniotomy.

    abstract:PURPOSE:To describe a newly recognized clinical syndrome consisting of ptosis, diplopia, vertical gaze limitation, and abduction weakness that can occur after orbital roof removal during orbito-zygomatic-pterional craniotomy. DESIGN:Case series. PARTICIPANTS:Eight study patients (7 women), 44 to 80 years of age, with...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2014.09.011

    authors: Desai SJ,Lawton MT,McDermott MW,Horton JC

    更新日期:2015-03-01 00:00:00

  • Treatment of recurrent squamous papillomata of the conjunctiva by carbon dioxide laser vaporization.

    abstract::Complete resection of recurrent conjunctival squamous papillomata frequently may be exceedingly difficult, since such lesions are typically friable and multilobulated. Recurrent lesions often fill the fornicies and spill onto the lid margins. Moreover, since the human papillomavirus (HPV) has been linked to some of th...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(86)33634-0

    authors: Bosniak SL,Novick NL,Sachs ME

    更新日期:1986-08-01 00:00:00

  • Ultrasound biomicroscopy in pseudophakic malignant glaucoma.

    abstract:BACKGROUND:Malignant glaucoma (ciliary block glaucoma; aqueous misdirection glaucoma) is an incompletely understood, rare and serious complication of intraocular surgery. METHODS:A woman with pseudophakic malignant glaucoma underwent successful neodymium: YAG (Nd:YAG) laser photodisruption of the anterior hyaloid face...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(93)31479-x

    authors: Tello C,Chi T,Shepps G,Liebmann J,Ritch R

    更新日期:1993-09-01 00:00:00

  • Removal of dislocated intraocular lenses using pars plana vitrectomy with placement of an open-loop, flexible anterior chamber lens.

    abstract:OBJECTIVE:There are many alternatives available to the vitreoretinal surgeon in the management of posteriorly dislocated intraocular lenses (IOL). The lens may be repositioned in the ciliary sulcus if there is adequate capsular support, but if this support is absent, it must either be sutured in place (to the sclera or...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/S0161-6420(98)96001-8

    authors: Mittra RA,Connor TB,Han DP,Koenig SB,Mieler WF,Pulido JS

    更新日期:1998-06-01 00:00:00

  • The Endophthalmitis Vitrectomy Study. Relationship between clinical presentation and microbiologic spectrum.

    abstract:PURPOSE:The authors determine if specific features of the clinical presentation of acute postoperative endophthalmitis correlated with the microbiologic culture results. METHODS:A total of 420 patients who had clinical evidence of endophthalmitis within 6 weeks after cataract surgery or secondary intraocular lens impl...

    journal_title:Ophthalmology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0161-6420(97)30326-1

    authors: Johnson MW,Doft BH,Kelsey SF,Barza M,Wilson LA,Barr CC,Wisniewski SR

    更新日期:1997-02-01 00:00:00

  • Conjunctival melanoma: outcomes based on tumor origin in 382 consecutive cases.

    abstract:PURPOSE:To evaluate prognostic factors based on origin of conjunctival melanoma. DESIGN:Interventional case series. PARTICIPANTS:Three hundred eighty-two consecutive patients. METHODS:Retrospective chart review. MAIN OUTCOME MEASURES:Melanoma-related metastasis and death. RESULTS:The melanoma arose from primary ac...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2010.06.021

    authors: Shields CL,Markowitz JS,Belinsky I,Schwartzstein H,George NS,Lally SE,Mashayekhi A,Shields JA

    更新日期:2011-02-01 00:00:00

  • The management of corneal perforations associated with rheumatoid arthritis. An analysis of 32 eyes.

    abstract:BACKGROUND:Sterile corneal ulceration is a rare complication of rheumatoid arthritis and may lead to corneal perforation. Surgical management for visual restoration frequently is unsuccessful. The authors analyze the factors that may determine the failure of corneal surgery in perforations associated with rheumatoid ar...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(95)30867-6

    authors: Bernauer W,Ficker LA,Watson PG,Dart JK

    更新日期:1995-09-01 00:00:00

  • Higher-order aberrations in eyes with irregular corneas after laser refractive surgery.

    abstract:PURPOSE:To investigate the distribution of the eye's higher-order aberrations in postoperative laser refractive surgery patients with visual complaints and highly irregular corneal shapes. DESIGN:Retrospective case-control study. PARTICIPANTS:Thirty-three symptomatic postoperative LASIK and/or photorefractive keratec...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2005.04.022

    authors: McCormick GJ,Porter J,Cox IG,MacRae S

    更新日期:2005-10-01 00:00:00

  • Evaluation of a computer-based system for plus disease diagnosis in retinopathy of prematurity.

    abstract:OBJECTIVE:To measure accuracy and reliability of the computer-based Retinal Image Multiscale Analysis (RISA) system compared with those of recognized retinopathy of prematurity (ROP) experts, for plus disease diagnosis. DESIGN:Evaluation of diagnostic test or technology. PARTICIPANTS:Eleven recognized ROP experts and...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2007.10.006

    authors: Koreen S,Gelman R,Martinez-Perez ME,Jiang L,Berrocal AM,Hess DJ,Flynn JT,Chiang MF

    更新日期:2007-12-01 00:00:00

  • Accuracy of RTVue optical coherence tomography, Pentacam, and ultrasonic pachymetry for the measurement of central corneal thickness.

    abstract:OBJECTIVE:To compare the reliability and the agreement in measuring central corneal thickness (CCT) using the following technologies: RTVue Fourier-domain optical coherence tomography (Optovue, Inc., Fremont, CA), Pentacam (Oculus, Inc., Wetzlar, Germany), and ultrasonic pachymetry (USP; Pocket-II; Quantel Medical, Inc...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2010.03.002

    authors: Nam SM,Im CY,Lee HK,Kim EK,Kim TI,Seo KY

    更新日期:2010-11-01 00:00:00

  • Vitrectomy techniques in retinal reattachment surgery.

    abstract::Vitreous surgery techniques are useful in the management of selected retinal detachments with an otherwise poor prognosis. Vitrectomy methods can be used to remove intraocular opacities; cut vitreous sheets causing vitreo-retinal traction and separate epiretinal membranes covering or distorting the retina; provide a f...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(79)35485-9

    authors: Michels RG

    更新日期:1979-04-01 00:00:00

  • Diffuse iris melanoma: a report of 25 cases.

    abstract:BACKGROUND:Diffuse iris melanoma is a rare variant of iris melanoma that has a flat growth pattern and often presents as unilateral hyperchromic heterochromia and glaucoma. There have been no large clinical reports of diffuse iris melanoma. DESIGN:Single-center retrospective case series. PARTICIPANTS:Twenty-five cons...

    journal_title:Ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1016/s0161-6420(02)01104-1

    authors: Demirci H,Shields CL,Shields JA,Eagle RC Jr,Honavar SG

    更新日期:2002-08-01 00:00:00

  • Long-term reproducibility of cirrus HD optical coherence tomography deviation map in clinically stable glaucomatous eyes.

    abstract:OBJECTIVE:To determine the long-term reproducibility of the retinal nerve fiber layer (RNFL) thickness deviation map in glaucoma patients. DESIGN:Retrospective, longitudinal study. PARTICIPANTS:One hundred two eyes of 102 glaucoma patients. METHODS:From a total of 318 screened glaucoma patients who had undergone at ...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2012.11.008

    authors: Roh KH,Jeoung JW,Park KH,Yoo BW,Kim DM

    更新日期:2013-05-01 00:00:00

  • Indocyanine green videoangiographic findings in detachment of the retinal pigment epithelium.

    abstract:BACKGROUND:Several forms of retinal pigment epithelial detachment have been reported. The authors used indocyanine green (ICG) videoangiography, which is useful to study the choroidal vasculature and Bruch membrane, to study pigment epithelial detachments. METHODS:Ninety-eight pigment epithelial detachments in 75 eyes...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/s0161-6420(95)30990-6

    authors: Yuzawa M,Kawamura A,Yamaguchi C,Shouda M,Shimoji M,Matsui M

    更新日期:1995-04-01 00:00:00

  • Quantitative iris parameters and association with narrow angles.

    abstract:PURPOSE:To investigate the relationship between quantitative iris parameters (iris curvature [I-Curv], iris area [I-Area], and iris thickness) and the presence of narrow angles. DESIGN:Cross-sectional, community-based study. PARTICIPANTS:We recruited 2047 subjects >50 years old without ophthalmic symptoms from a comm...

    journal_title:Ophthalmology

    pub_type: 杂志文章

    doi:10.1016/j.ophtha.2009.06.017

    authors: Wang B,Sakata LM,Friedman DS,Chan YH,He M,Lavanya R,Wong TY,Aung T

    更新日期:2010-01-01 00:00:00