Abstract:
OBJECTIVE:To determine the long-term reproducibility of the retinal nerve fiber layer (RNFL) thickness deviation map in glaucoma patients. DESIGN:Retrospective, longitudinal study. PARTICIPANTS:One hundred two eyes of 102 glaucoma patients. METHODS:From a total of 318 screened glaucoma patients who had undergone at least 3 serial Cirrus HD optical coherence tomography sessions during an 18-month or longer follow-up period, 102 eyes with localized RNFL defects on red-free photographs that did not progress during this period based on stereoscopic disc photography, red-free photography, and standard automated perimetry (SAP) were included. The angular widths from the RNFL thickness deviation maps and average, clock-hour, and quadrant-map thicknesses of the RNFL defects were measured serially to assess intersession variability. MAIN OUTCOME MEASURES:Intraclass correlation coefficient (ICC), coefficient of variation (CV), test-retest standard deviation (TRT SD), and tolerance limit. RESULTS:The ICC, CV, and TRT SD were 0.994, 4.2%, and 1.46°, respectively, for the angular widths; 0.944, 3.1%, and 2.35 μm, respectively, for the average thicknesses; and 0.840 and 0.934, 7.8% and 6.4%, and 7.21 and 5.58 μm, respectively, for the superior and inferior quadrant positions of the RNFL defects. The severity of glaucoma based on the mean deviation of SAP did not affect the reproducibility of the angular widths (TRT SD, 1.3° and 1.84°, respectively; P = 0.905). CONCLUSIONS:Both the angular widths of RNFL defects in the RNFL thickness deviation map and conventional peripapillary thickness parameters exhibit excellent long-term reproducibility. FINANCIAL DISCLOSURE(S):The author(s) have no proprietary or commercial interest in any materials discussed in this article.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Roh KH,Jeoung JW,Park KH,Yoo BW,Kim DMdoi
10.1016/j.ophtha.2012.11.008subject
Has Abstractpub_date
2013-05-01 00:00:00pages
969-77issue
5eissn
0161-6420issn
1549-4713pii
S0161-6420(12)01074-3journal_volume
120pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract:PURPOSE:To characterize quantitatively the configuration of the anterior ocular segment with ultrasound biomicroscopy (UBM) in a population-based setting. DESIGN:Cross-sectional study. PARTICIPANTS:Ten percent of 4632 residents aged > or =40 years of Kumejima, an island off southwest Japan, were randomly selected. M...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.01.045
更新日期:2010-09-01 00:00:00
abstract:PURPOSE:Multifocal lenses have been shown to produce enhanced near and intermediate vision. The division of incoming light into more than one focal point must physically produce retinal images of reduced contrast. The purpose of this report is to provide quantitative data on the increased depth of focus and decreased c...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(92)31735-x
更新日期:1992-11-01 00:00:00
abstract:AIM:To report a rare presentation of colloid milium occurring only on the upper eyelid margins. DESIGN:Interventional case report. METHODS:(1) Slit-lamp examination of eyelids and eyes and clinical examination including the face and a general physical examination; (2) photography of the lesions on the lids; and (3) e...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(02)01180-6
更新日期:2002-10-01 00:00:00
abstract::Arteriohepatic dysplasia (AHD, Alagille's syndrome) is presumed to be one of the six known familial intrahepatic cholestatic syndromes, all of which present with neonatal jaundice or failure to thrive, or both. Accurate early diagnosis of the proper syndrome is important, as arteriohepatic dysplasia has a good prognos...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(81)35026-x
更新日期:1981-04-01 00:00:00
abstract:PURPOSE:To evaluate prospectively the efficacy of a single sub-Tenon's capsule injection of triamcinolone acetonide (TA) against panretinal photocoagulation (PRP)-induced macular thickening and visual disturbance in patients with severe diabetic retinopathy and good vision. DESIGN:Prospective, comparative, interventio...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2005.10.035
更新日期:2006-03-01 00:00:00
abstract::From 1984 to 1989, 24 patients with desperate ocular surface wetting problems due to mucus deficiency syndrome with extensive symblephara or lid fusion were treated by autologous free transplants of nasal mucosa from the nasal conchae. This procedure covers the ocular surface not only with nonkeratinizing epithelium b...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(90)32471-5
更新日期:1990-08-01 00:00:00
abstract:PURPOSE:To determine efficacy and safety of intravitreal aflibercept in patients with neovascular age-related macular degeneration (AMD) during a second year of variable dosing after a first-year fixed-dosing period. DESIGN:Two randomized, double-masked, active-controlled, phase 3 trials. PARTICIPANTS:Two thousand fo...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ophtha.2013.08.011
更新日期:2014-01-01 00:00:00
abstract::This article discusses the experience of progressing from a young ophthalmic resident to a full-time professional and, ultimately, to service on the American Board of Ophthalmology. ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2016.06.013
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To analyze the success rate of pulsed intravenous (IV) cyclophosphamide (CyP) for noninfectious ocular inflammatory disease and to identify risk factors for failure of therapy. DESIGN:Retrospective, interventional, noncomparative cohort study. PARTICIPANTS:One hundred ten eyes of 65 patients. METHODS:Through...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2013.01.031
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To assess associations between health-related quality of life (HRQOL) and the decision to perform strabismus surgery for children with intermittent exotropia. DESIGN:Retrospective chart review. PARTICIPANTS:Children with intermittent exotropia. METHODS:Included subjects, identified in a clinical practice, ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2013.10.029
更新日期:2014-04-01 00:00:00
abstract:PURPOSE:Several retrospective studies have demonstrated the safety and efficacy of sub-Tenon's anesthesia in ocular surgery. This is the first prospective randomized study comparing sub-Tenon's versus retrobulbar anesthesia for glaucoma surgery. METHODS:Thirty-nine patients undergoing both inpatient and day surgery tr...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0161-6420(93)31440-5
更新日期:1993-10-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of eyelid, conjunctival, and corneal findings in patients with sleep apnea syndrome (SAS). DESIGN:Case series. PARTICIPANTS:Seventy-two white patients referred for evaluation of suspected SAS. INTERVENTION:Complete examination of eyelids, conjunctiva, and cornea, including video...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(99)90256-7
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVE:To determine if topical ketorolac 0.5% relieves the symptoms and signs of viral conjunctivitis better than artificial tears. DESIGN:Randomized, controlled trial. PARTICIPANTS:One hundred seventeen patients with a clinical diagnosis of viral conjunctivitis were randomized to the treatment group or control gr...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0161-6420(00)00177-9
更新日期:2000-08-01 00:00:00
abstract:PURPOSE:To investigate the ability of sectorial analysis using the Heidelberg Retinal Tomograph 3 (HRT3) to discriminate between healthy and glaucomatous eyes and to determine whether this is affected by disc size and glaucoma severity. DESIGN:Multicenter, cross-sectional evaluation of diagnostic tests. PARTICIPANTS:...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2009.01.020
更新日期:2009-06-01 00:00:00
abstract::Nodular, gray-white, central corneal opacities which extended from the subepithelial zone through the anterior four fifths of the stroma developed in a 50-year-old man with a longstanding history of hard contact lens wear for keratoconus. Results of histopathologic analysis of the corneal button obtained at the time o...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(88)33225-2
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:To describe a cohort of patients with pars planitis followed at a single tertiary care institution, determine the frequency of multiple sclerosis and/or optic neuritis in patients with this disorder, and calculate gene frequencies of human leukocyte antigen (HLA) class II alleles in these patients. DESIGN:Fi...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(99)90122-7
更新日期:1999-03-01 00:00:00
abstract:PURPOSE:To determine the impact that cataract and cataract surgery have on clinical measurements of vision, reading speed, objective mobility performance, and subjective visual functioning. DESIGN:Prospective, population-based study. PARTICIPANTS:A total of 1739 Salisbury Eye Evaluation (SEE) participants without pre...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.10.009
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:To determine the prevalence of relative anterior microphthalmos (RAM) and evaluate intraoperative performance and surgical outcome in eyes with RAM undergoing cataract surgery. DESIGN:Nested case-control series. PARTICIPANTS:One thousand four hundred consecutive patients undergoing cataract surgery were evalu...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2005.02.027
更新日期:2005-08-01 00:00:00
abstract:PURPOSE:To use in vivo confocal microscopy (IVCM) to quantitatively analyze microstructural changes over time, after corneal collagen cross-linking for keratoconus. DESIGN:Prospective cohort study. PARTICIPANTS:A total of 38 eyes of 38 patients undergoing collagen cross-linking for keratoconus. METHODS:Prospective, ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2013.09.014
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVE:To evaluate extraocular muscle surgery associated with plaque brachytherapy for choroidal melanoma. DESIGN:Single-center retrospective cohort study. PARTICIPANTS:Three hundred twenty-nine eyes of 329 consecutive patients with clinically diagnosed choroidal melanoma. INTERVENTION:Palladium 103 plaque brachy...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2014.05.037
更新日期:2014-11-01 00:00:00
abstract:PURPOSE:To describe the relationship between chronic systemic immune suppression and conjunctival squamous cell carcinoma (SCC). DESIGN:Retrospective interventional case series. PARTICIPANTS:Thirteen immunosuppressed patients with conjunctival SCC. METHODS:Surgical excision in all cases plus additional topical inter...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2011.04.001
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:To report cases of Avellino corneal dystrophy (ACD) exacerbated by LASIK for myopia. DESIGN:Retrospective, noncomparative, interventional case series and review of the literature. PARTICIPANTS:Seven patients. INTERVENTION:Six patients with exacerbation of granular corneal deposits after LASIK were examined...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2003.06.026
更新日期:2004-03-01 00:00:00
abstract::For a period of three years, more than 2,700 endothelial cell density measurements were performed in over 1,000 patients undergoing cataract extraction with and without intraocular lens implantation. We concluded the following from the data: (1) Significant cell loss occurred with all surgical procedures, averaging be...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(82)34856-3
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVE:Syndromes with genetically determined retinal diseases and concurrent multiple neurologic abnormalities are rare. Kjellin described an autosomal recessive entity with spastic paraplegia, mental retardation, amyotrophia, and macular dystrophy. We sought to further characterize the retinal phenotype and to cont...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(02)01110-7
更新日期:2002-08-01 00:00:00
abstract:PURPOSE:The objective of the study was to evaluate the accuracy of the Notal OCT Analyzer (NOA) versus that of a retina specialist (RS) in the automated detection of fluid on optical coherence tomography (OCT). DESIGN:A study of the performance of the NOA compared with the results from 3 RSs. PARTICIPANTS:A selection...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2016.04.005
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the safety and efficacy of transnasal orbital decompression for severe Graves' ophthalmopathy. DESIGN:Retrospective noncomparative case series with extended clinical follow-up. PARTICIPANTS:Seventy-eight consecutive subjects who were operated on for compressive optic neuropathy with loss of visu...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(00)00533-9
更新日期:2001-02-01 00:00:00
abstract:PURPOSE:To investigate the relationship between idiopathic nonarteritic ischemic optic neuropathy (NAION) and serum lipid levels in patients = 50 years of age. DESIGN:Case-control study. PARTICIPANTS:Thirty-seven consecutive patients with NAION and 74 age- and gender-matched comparison patients. METHODS AND MAIN O...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(03)00079-4
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:To provide an initial assessment of the safety of a recombinant adeno-associated virus vector expressing RPE65 (rAAV2-CB-hRPE65) in adults and children with retinal degeneration caused by RPE65 mutations. DESIGN:Nonrandomized, multicenter clinical trial. PARTICIPANTS:Eight adults and 4 children, 6 to 39 years...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.ophtha.2016.03.003
更新日期:2016-07-01 00:00:00
abstract::Forty-nine patients, ages 3 to 18 years, who sustained nonpenetrating unilateral trauma with hyphemas were assigned randomly to receive either 100 mg/kg of epsilon-aminocaproic acid (EACA), an antifibrinolytic agent, orally every 4 hours for 5 days (maximum 30 g/day) or a placebo. No patients ingested acetylsalicylic ...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0161-6420(87)80005-2
更新日期:1987-10-01 00:00:00
abstract:OBJECTIVE:To estimate the psychometric properties of a vision-targeted measure of health-related quality of life, the National Eye Institute-Refractive Error Quality of Life survey (NEI-RQL), which includes 13 scales designed to assess the impact of refractive error and its correction on day-to-day life. DESIGN:Cross-...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2002.07.001
更新日期:2003-12-01 00:00:00