Abstract:
OBJECTIVE:To determine the prevalence of eyelid, conjunctival, and corneal findings in patients with sleep apnea syndrome (SAS). DESIGN:Case series. PARTICIPANTS:Seventy-two white patients referred for evaluation of suspected SAS. INTERVENTION:Complete examination of eyelids, conjunctiva, and cornea, including videokeratography. MAIN OUTCOME MEASURES:Spearman rank correlations were determined between the respiratory disturbance index (RDI) during night sleep, a value used to diagnose and grade SAS, and tear film break-up time, eyelid distraction distance, presence or absence of ocular irritation symptoms, blepharoptosis, floppy eyelids, lacrimal gland prolapse, keratoconus, and endothelial dystrophy. Each correlation was controlled for age and body mass index. RESULTS:According to the RDI, 44 (61 %) of the 72 patients had SAS. The RDI correlated positively with the eyelid distraction distance (P = 0.05), presence or absence of floppy eyelids (P = 0.01), and lacrimal gland prolapse (P = 0.01), and correlated negatively with tear film break-up time (P = 0.02). None of our patients with floppy eyelids had corneal abnormalities. One patient with SAS had bilateral keratoconus; another had bilateral Fuch endothelial dystrophy. CONCLUSIONS:Sleep apnea syndrome was significantly associated with reduced tear film break-up time, floppy eyelids, and lacrimal gland prolapse. However, ocular irritation symptoms and corneal involvement were rare among patients with SAS. These findings do not confirm previous studies that reported a high prevalence of corneal involvement in floppy eyelid syndrome.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Mojon DS,Goldblum D,Fleischhauer J,Chiou AG,Frueh BE,Hess CW,Gugger M,Bassetti C,Boehnke M,Mathis Jdoi
10.1016/S0161-6420(99)90256-7subject
Has Abstractpub_date
1999-06-01 00:00:00pages
1182-5issue
6eissn
0161-6420issn
1549-4713pii
S0161-6420(99)90256-7journal_volume
106pub_type
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