当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Hydrodynamic delivery of IL-28B (IFN-λ3) gene ameliorates lung inflammation induced by cigarette smoke exposure in mice.

Hydrodynamic delivery of IL-28B (IFN-λ3) gene ameliorates lung inflammation induced by cigarette smoke exposure in mice.

Abstract：

:Cigarette smoke (CS) is the principal cause of pulmonary inflammatory response. IL-28 (IFN-λ) is a novel group of class II cytokines targeting the epithelial cells and IL-28 responses prominent in lungs can exert important immunomodulatory effects. We tested the hypothesis that IL-28B may modulate the lung inflammation induced by CS. Groups of mice were exposed to CS two times per day for 11 consecutive days. CS exposure induced lymphocyte, neutrophil and macrophage infiltration and inflammatory cytokine (IL-1β, tumor necrosis factor-α (TNF)-α, IL-17, and IL-4) in the airways. More importantly, all these CS-induced pathogenic changes were significantly inhibited by hydrodynamic delivery of plasmid DNA encoding mouse IL-28B. Thus, our results suggest that IL-28 cytokines are beneficial for the suppression of CS-mediated airway inflammation and may be a therapeutic target in CS-related diseases.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Qiu C,Li Y,Zhou M,Liu J,Li M,Wu Y,Xu D,Li M

doi

10.1016/j.bbrc.2014.04.010

subject

Has Abstract

pub_date

2014-05-09 00:00:00

pages

513-9

issue

3

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(14)00641-X

journal_volume

447

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Isolation and crystallization of functionally competent Escherichia coli peptide deformylase forms containing either iron or nickel in the active site.

    abstract：:Three metallo forms of peptide deformylase (PDF, EC 3.5.1.31) of Escherichia coli were prepared and crystallized (space group C2, diffraction limit 1.9 A) for initiating the X-ray structure determination of the metal center in correlation with the catalytic functionality of this enzyme. The native Fe2+ containing enzy...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1998.8616

    authors： Groche D,Becker A,Schlichting I,Kabsch W,Schultz S,Wagner AF

    更新日期：1998-05-19 00:00:00

  • Analysis of self-association of West Nile virus capsid protein and the crucial role played by Trp 69 in homodimerization.

    abstract：:The understanding of capsid (C) protein interactions with itself would provide important data on how the core is organized in flaviviruses during assembly. In this study, West Nile (WN) virus C protein was shown to form homodimers using yeast two-hybrid analysis in conjunction with mammalian two-hybrid and in vivo co-...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.01.121

    authors： Bhuvanakantham R,Ng ML

    更新日期：2005-04-01 00:00:00

  • The δA isoform of calmodulin kinase II mediates pathological cardiac hypertrophy by interfering with the HDAC4-MEF2 signaling pathway.

    abstract：:Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is a new promising target for prevention and treatment of cardiac hypertrophy and heart failure. There are three δ isoforms of CaMKII in the heart and previous studies focused primarily on δB and δC types. Here we report the δA isoform of CaMKII is also critically...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2011.04.128

    authors： Li C,Cai X,Sun H,Bai T,Zheng X,Zhou XW,Chen X,Gill DL,Li J,Tang XD

    更新日期：2011-05-27 00:00:00

  • Channel formation in planar lipid bilayers by a neurotoxic fragment of the beta-amyloid peptide.

    abstract：:Alzheimer's disease (AD) pathology is characterized by plaques, tangles, and neuronal cell loss. The main constituent of plaques is beta-amyloid peptide (A beta), a 39-42 residue peptide which has been linked to disruption of calcium homeostasis and neurotoxicity in vitro. We demonstrate that a neurotoxic fragment of ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1994.2047

    authors： Mirzabekov T,Lin MC,Yuan WL,Marshall PJ,Carman M,Tomaselli K,Lieberburg I,Kagan BL

    更新日期：1994-07-29 00:00:00

  • Copper-induced oxidation of epinephrine: protective effect of D-DAHK, a synthetic analogue of the high affinity copper binding site of human albumin.

    abstract：:Epinephrine is known to be rapidly oxidized during sepsis. Ischemia and acidosis, which often accompany sepsis, are associated with the release of weakly bound cupric ions from plasma proteins. We investigated whether copper promotes oxidation of epinephrine at both physiological and acidic pH and whether D-Asp-D-Ala-...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(03)00667-3

    authors： Roberts A,Bar-Or D,Winkler JV,Rael LT

    更新日期：2003-05-16 00:00:00

  • Carnosine is a quencher of 4-hydroxy-nonenal: through what mechanism of reaction?

    abstract：:The aim of this study was to understand the mechanism of action through which carnosine (beta-alanyl-L-histidine) acts as a quencher of cytotoxic alpha,beta-unsaturated aldehydes, using 4-hydroxy-trans-2,3-nonenal (HNE) as a model aldehyde. In phosphate buffer solution (pH 7.4), carnosine was 10 times more active as a...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(02)02545-7

    authors： Aldini G,Carini M,Beretta G,Bradamante S,Facino RM

    更新日期：2002-11-15 00:00:00

  • Nucleotidyl cyclase activity of soluble guanylyl cyclase in intact cells.

    abstract：:Soluble guanylyl cyclase (sGC) is activated by nitric oxide (NO) and generates the second messenger cyclic GMP (cGMP). Recently, purified sGC α1β1 has been shown to additionally generate the cyclic pyrimidine nucleotides cCMP and cUMP. However, since cyclic pyrimidine nucleotide formation occurred only the presence of...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2013.12.108

    authors： Bähre H,Danker KY,Stasch JP,Kaever V,Seifert R

    更新日期：2014-01-24 00:00:00

  • Biphasic influence of pravastatin on human cardiac microvascular endothelial cell functions under pathological and physiological conditions.

    abstract：:HMG-CoA reductase inhibitor statins are used to treat patients with hypercholesterolemia. The pleiotropic effects of statins have been recently extended to the regulation of angiogenesis. However, the observations on the effects of statins on endothelial cells seem to be contradictory. In this work, we systematically ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.02.090

    authors： Hu K,Wan Q

    更新日期：2019-04-02 00:00:00

  • Evidence that the protein components of bovine erythrocyte green heme binding protein and flavin reductase are identical.

    abstract：:Bovine erythrocyte green heme binding protein and bovine erythrocyte flavin reductase have been isolated in highly purified forms and subjected to amino acid analysis and N-terminal amino acid sequence analysis. The two proteins possess similar amino acid compositions and identical N-terminal amino acid sequences. Mor...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(91)91816-u

    authors： Quandt KS,Xu F,Chen P,Hultquist DE

    更新日期：1991-07-15 00:00:00

  • The small-molecule IAP antagonist AT406 inhibits pancreatic cancer cells in vitro and in vivo.

    abstract：:In the present study, we tested the anti-pancreatic cancer activity by AT406, a small-molecule antagonist of IAP (inhibitor of apoptosis proteins). In established (Panc-1 and Mia-PaCa-2 lines) and primary human pancreatic cancer cells, treatment of AT406 significantly inhibited cell survival and proliferation. Yet, sa...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2016.07.011

    authors： Jiang Y,Meng Q,Chen B,Shen H,Yan B,Sun B

    更新日期：2016-09-09 00:00:00

  • Maternal circulating syncytiotrophoblast-derived extracellular vesicles contain biologically active 5'-tRNA halves.

    abstract：:The placenta releases syncytiotrophoblast-derived extracellular vesicles (STB-EV) into the maternal circulation throughout gestation. STB-EV dependent signalling is believed to contribute to the widespread maternal adaptive physiological changes seen in pregnancy. Transfer RNA (tRNA) halves have been identified in ves...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.08.015

    authors： Cooke WR,Cribbs A,Zhang W,Kandzija N,Motta-Mejia C,Dombi E,Ri R,Cerdeira AS,Redman C,Vatish M

    更新日期：2019-10-08 00:00:00

  • Casein kinase II-catalysed phosphorylation of calmodulin is altered by amino acid deletions in the central helix of calmodulin.

    abstract：:Calmodulin is phosphorylated by casein kinase II on Thr-79, Ser-81, Ser-101 and Thr-117. To determine the consensus sequences for casein kinase II in intact calmodulin, we examined casein kinase II-mediated phosphorylation of engineered calmodulins with 1-4 deletions in the central helical region (positions 81-84). To...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(92)91120-f

    authors： Sacks DB,Davis HW,Crimmins DL,Persechini A,McDonald JM

    更新日期：1992-10-30 00:00:00

  • Applications of mass spectrometry-based targeted and non-targeted lipidomics.

    abstract：:Recent advances in mass spectrometry have expanded our knowledge of lipids and lipid metabolic pathways involved in many (patho)physiological events. Targeted and non-targeted lipidomics are powerful analytical strategies with distinct features, and a combination of these two approaches is often employed to maximize t...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章,评审

    doi：10.1016/j.bbrc.2018.03.081

    authors： Lee HC,Yokomizo T

    更新日期：2018-10-07 00:00:00

  • Steroid-lipid interactions in sonicated dipalmitoyl phosphatidyl choline vesicles: a steady-state and time-resolved fluorescence anisotropy study with all trans-1,6-diphenyl-1,3,5-hexatriene as probe.

    abstract：:The effect of steroid chemical structure on steroid-lipid interaction is studied in sonicated dipalmitoyl phosphatidylcholine vesicles by steady-state and time-resolved fluorescence anisotropy techniques using diphenylhexatriene as probe. A large number of cholesterol derivatives and steroids, some of them being precu...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(83)91070-7

    authors： Vincent M,Gallay J

    更新日期：1983-06-29 00:00:00

  • Human thyroperoxidase folds in one complex B-cell immunodominant region.

    abstract：:Human thyroperoxidase (TPO) ectodomain is successively made of myeloperoxidase-, complement control protein repeat-, and epidermal growth factor-like gene modules. However, the TPO immunodominant region targeted by autoantibodies from patients with an autoimmune thyroid disease has not been mapped on the molecule. Her...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(02)00827-6

    authors： Blanchin S,Estienne V,Guo J,Rapoport B,McLachlan SM,Carayon P,Ruf J

    更新日期：2002-08-02 00:00:00

  • Dickkopf-1 induced apoptosis in human placental choriocarcinoma is independent of canonical Wnt signaling.

    abstract：:Placental choriocarcinoma, a reproductive system carcinoma in women, has about 0.81% occurrence frequency in China, which leads to over 90% lethality due to indistinct pathogenesis and the absence of efficient therapeutic treatment. In the present study, using immunostaining and reverse transcription PCR, we reported ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.09.087

    authors： Peng S,Miao C,Li J,Fan X,Cao Y,Duan E

    更新日期：2006-11-24 00:00:00

  • One in vitro model for visceral adipose-derived fibroblasts in chronic inflammation.

    abstract：:One pathogenesis of the obesity-associated complications is that consistent with increased body fat mass, the elevation of adipose tissue-derived cytokines inflicts a low-grade chronic inflammation, which ultimately leads to metabolic disorders. Adipocytes and macrophages in visceral adipose (VA) have been confirmed t...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.05.182

    authors： Yue GP,Du LR,Xia T,He XH,Qiu H,Xu LH,Chen XD,Feng SQ,Yang ZQ

    更新日期：2005-08-05 00:00:00

  • Characterization of Erwinia chrysanthemi PY35 cel and pel gene existing in tandem and rapid identification of their gene products.

    abstract：:Genomic DNA of the phytopathogenic Erwinia chrysanthemi PY35 was partially digested with Sau3AI, ligated into the BamHI site of pBluescript II SK+, and introduced into E. coli. One clone that was able to hydrolyse carboxymethylcellulose and polygalacturonic acid was selected. A 2.9 kb fragment containing the pelL1 gen...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.2137

    authors： Park SR,Kim MK,Kim JO,Bae DW,Cho SJ,Cho YU,Yun HD

    更新日期：2000-02-16 00:00:00

  • Nuclear and cytoplasmic localization of the beta-amyloid peptide (1-43) in transfected 293 cells.

    abstract：:Cultures of transformed human embryonic kidney 293 cells were transiently transfected with minigene constructs coding for the Abeta peptide (1-43). The Abeta minigene used in this study consisted of exons 16 and 17 of the amyloid precursor protein gene, including the 6000+ bp intronic region. Two of the constructs use...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1996.0469

    authors： Johnstone EM,Babbey LE,Stephenson D,Paul DC,Santerre RF,Clemens JA,Williams DC,Little SP

    更新日期：1996-03-27 00:00:00

  • Forskolin and prostacyclin inhibit fluoride induced platelet activation and protein kinase C dependent responses.

    abstract：:Platelet activation (cytosolic [Ca2+] increase, aggregation and ATP secretion) was induced with A1F-4. This agent presumably interacts with a G protein which appears to mediate the coupling of the receptors for Ca mobilizing hormones and phospholipase C. All the A1F-4 evoked responses were inhibited by treatment with ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(88)80776-9

    authors： Doni MG,Deana R,Bertoncello S,Zoccarato F,Alexandre A

    更新日期：1988-11-15 00:00:00

  • Hepatic CD147 knockout modulates liver steatosis and up-regulates autophagy in high-fat-diet-induced NAFLD mice.

    abstract：:Nonalcoholic fatty liver disease (NAFLD) represents a global health problem. Impaired autophagy has been implicated in the pathogenesis of NAFLD, and CD147 is recognized to regulate lipid metabolism in a variety of cell types. This study was initiated with the aim to identify molecular makers expressed in hepatocytes ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2020.01.164

    authors： Lou J,Li C,Li ZS,Zhang T,Chen ZN,Bian H

    更新日期：2020-04-16 00:00:00

  • Variable amounts of translatable ferritin mRNA in bean leaves with various iron contents.

    abstract：:RNA was isolated from bean leaves with various iron and ferritin contents. The amount of translatable ferritin mRNA in these RNAs was determined by wheat-germ cell-free translation and immunoprecipitation with anti-bean seed ferritin serum. The levels of ferritin mRNA present in total RNA of the leaves are reflected b...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(83)80167-3

    authors： van der Mark F,Bienfait F,van den Ende H

    更新日期：1983-09-15 00:00:00

  • Chimeric caspase molecules with potent cell killing activity in apoptosis-resistant cells.

    abstract：:Cellular defects which prevent apoptotic cell death can result in the generation of hyperproliferative disorders and can prevent the effective treatment of such diseases. The majority of cellular defects which result in apoptosis resistance lie upstream of caspase activation. We have described chimeric caspase molecul...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.4699

    authors： Shearwin-Whyatt L,Baliga B,Doumanis J,Kumar S

    更新日期：2001-04-20 00:00:00

  • Inhibitory effect of memantine, an NMDA-receptor antagonist, on electroporation-induced inward currents in pituitary GH3 cells.

    abstract：:The membrane electroporation-induced inward current (IMEP) in pituitary tumor (GH3) cells was characterized. This current emerges irregularly when membrane hyperpolarizations to -200 mV with a holding potential of -80 mV were elicited. Neither E-4031 (10 μM), glibenclamide (30 μM), nor ZD7288 (30 μM) caused any effect...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2011.01.066

    authors： Wu SN,Huang HC,Yeh CC,Yang WH,Lo YC

    更新日期：2011-02-18 00:00:00

  • Molecular cloning and characterization of a novel human gene containing ankyrin repeat and double BTB/POZ domain.

    abstract：:A novel human gene containing an ankyrin repeat and BTB/POZ domains (BPOZ) was isolated from a human leukocyte cDNA library. The cDNA sequence contains an open reading frame of 1434 bp that encodes 478 amino acid residues with a predicted molecular mass of 53.9 kDa. Sequence pattern analysis shows that BPOZ contains a...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.3053

    authors： Dai KS,Wei W,Liew CC

    更新日期：2000-07-14 00:00:00

  • The vWFA2 domain of type VII collagen is responsible for collagen binding.

    abstract：:Type VII collagen (Col7) is the major component of anchoring fibrils and very important for skin integrity. This is emphasized by the Col7 related skin blistering diseases dystrophic epidermolysis bullosa and epidermolysis bullosa acquisita. Structural data that provides insights into the interaction network of Col7 a...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.11.119

    authors： Wegener H,Leineweber S,Seeger K

    更新日期：2013-01-11 00:00:00

  • Sulfation of iodothyronines by recombinant human liver steroid sulfotransferases.

    abstract：:Sulfation is an important pathway in the metabolism of thyroid hormones. Sulfated iodothyronines are elevated in nonthyroidal illnesses and in the normal human fetal circulation. We assayed and characterized COS-1 cell expressed recombinant human liver dehydroepiandrosterone sulfotransferase (DHEA ST or SULT2A1) and e...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1999.1419

    authors： Li X,Anderson RJ

    更新日期：1999-10-05 00:00:00

  • Ophiopogonin D alleviates cardiac hypertrophy in rat by upregulating CYP2J3 in vitro and suppressing inflammation in vivo.

    abstract：:Ophiopogonin D (OPD) is the chief pharmacological active component of the traditional Chinese herbal prescription drug-Shenmai injection (SMI), which has been used to prevent and treat cardiovascular diseases. In the present study, we investigated whether OPD protectively relieve cardiac hypertrophy against inflammati...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.06.110

    authors： Wang Y,Huang X,Ma Z,Wang Y,Chen X,Gao Y

    更新日期：2018-09-05 00:00:00

  • Ligand-induced functions of the epidermal growth factor receptor require the positively charged region asymmetrically distributed across plasma membrane.

    abstract：:Many plasma membrane proteins, including the epidermal growth factor (EGF) receptor, possess basic regions on the cytoplasmic surface of the membrane. To examine the function of these positively charged regions, we constructed mutated EGF receptor genes lacking this region by substitution of the basic amino acid resid...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(05)80024-5

    authors： Yamane K,Toyoshima C,Nishimura S

    更新日期：1992-05-15 00:00:00

  • Differential COX-2 induction by viral and bacterial PAMPs: Consequences for cytokine and interferon responses and implications for anti-viral COX-2 directed therapies.

    abstract：:Cyclooxygenase 2 (COX)-2 is induced by bacterial and viral infections and has complex, poorly understood roles in anti-pathogen immunity. Here, we use a knock-in luciferase reporter model to image Cox2 expression across a range of tissues in mice following treatment with the either the prototypical bacterial pathogen-...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2013.07.006

    authors： Kirkby NS,Zaiss AK,Wright WR,Jiao J,Chan MV,Warner TD,Herschman HR,Mitchell JA

    更新日期：2013-08-23 00:00:00