The auditory brainstem response (ABR) evaluates risk factors for hearing loss in the newborn.

abstract：:In seven patients with mucopolysaccharidoses (1 Hurler, 1 Hurler-Scheie, 4 Hunter, 1 Sly), cranial (1)H-magnetic resonance spectroscopy was performed to evaluate the accumulation of mucopolysaccharides and biochemical changes in the CNS in vivo before and after bone marrow transplantation (BMT). In two of seven patien...

journal_title：Pediatric research

authors： Takahashi Y,Sukegawa K,Aoki M,Ito A,Suzuki K,Sakaguchi H,Watanabe M,Isogai K,Mizuno S,Hoshi H,Kuwata K,Tomatsu S,Kato S,Ito T,Kondo N,Orii T

更新日期：2001-03-01 00:00:00

abstract：:Vitamin K deficiency is a relatively common condition in neonates. However, the role of vitamin K in neonatal bone metabolism remains to be determined. Osteocalcin (OC) is the most abundant noncollagenous protein in bone, and is regulated to be gamma-carboxylated by vitamin K. In this study, we measured gamma-carboxyl...

journal_title：Pediatric research

authors： Shimizu N,Shima M,Hirai H,Nakajima S,Nishimura K,Yamaoka K,Okada S

更新日期：2002-11-01 00:00:00

abstract：:Changes in high-density lipoprotein (HDL) subclass distribution were evaluated in a group of premature infants during the early postnatal period to ascertain whether enteral feeding brought about a rapid shift from neonatal to adult-like distributions. All infants were fed a combination of breast milk and formula. Cor...

journal_title：Pediatric research

authors： Genzel-Boroviczény O,D'Harlingue AE,Kao LC,Scott C,Forte TM

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Regular physical activity provides children with health and developmental benefits. This study investigated if active play and walking with the family dog was associated with better social-emotional development in young children. METHODS:We surveyed 1646 parents to ascertain if families with pre-schoolers o...

journal_title：Pediatric research

authors： Wenden EJ,Lester L,Zubrick SR,Ng M,Christian HE

更新日期：2020-07-06 00:00:00

abstract：:Epidermal growth factor (EGF), a potent mitogen present in milk, is postulated to play an important physiologic role in the ontogeny of the intestine. An artificial rat milk, free of EGF, was developed and fed to newborn rats in an effort to evaluate the physiologic role of EGF on intestinal glucose transport. Compari...

journal_title：Pediatric research

authors： Greene HL,Moore MC,Said HM,Ghishan FK,Orth DN

更新日期：1987-04-01 00:00:00

abstract：:Several lines of evidence suggest that formula with protein content of 3.0 g/100 kcal does not fully meet the protein needs of very-low-birth weight infants. Our purpose was to compare nitrogen balance, metabolic status and growth in infants fed a standard (3.0 g/100 kcal; RegPro) and high (3.6 g/100 kcal; HiPro) prot...

journal_title：Pediatric research

authors： Cooke R,Embleton N,Rigo J,Carrie A,Haschke F,Ziegler E

更新日期：2006-02-01 00:00:00

abstract：:BackgroundHyperoxic lung injury is characterized by cellular damage from high oxygen concentrations that lead to an inflammatory response and it disrupts normal alveolarization in the developing newborn lung. Adenosine is a signaling molecule that is generated extracellularly by ecto-5'-nucleotidase (CD73) in response...

journal_title：Pediatric research

authors： Li H,Karmouty-Quintana H,Chen NY,Mills T,Molina J,Blackburn MR,Davies J

更新日期：2017-08-23 00:00:00

abstract：:This study was aimed at describing abdominal and laryngeal muscle responses to upper airway occlusion (UAO) in early life and the effect of sleep states on these responses. Twelve nonsedated, 9-26-d-old lambs were studied. We simultaneously recorded 1) airflow (pneumotachograph + face mask); 2) sleep states (electroco...

journal_title：Pediatric research

authors： Kianicka I,Praud JP

更新日期：1997-06-01 00:00:00

abstract：:Neonatal group B streptococcal (GBS) sepsis produces pulmonary arterial hypertension and hypoxemia that are preventable by pretreatment with the selective thromboxane A2 synthase inhibitor, dazmegrel. In the present experiment we administered dazmegrel (8 mg/kg) 2 h after the initiation of a 2 1/2 h infusion of 5 X 10...

journal_title：Pediatric research

authors： Truog WE,Gibson RL,Juul SE,Henderson WR,Redding GJ

更新日期：1988-04-01 00:00:00

abstract：:The effect of various lipids, proteins, and other substances on the adsorption rate of dipalmitoyl phosphatidylcholine (DPC) was investigated. Each substance was added to a sonicated suspension of DPC in saline, and the surface pressure of the adsorbed surface film was measured using a platinum plate suspended from an...

journal_title：Pediatric research

authors： Meban C

更新日期：1981-07-01 00:00:00

abstract：:Cancer stem cells (CSC) are recently proposed to be the cancer initiating cells responsible for tumorigenesis and contribute to cancer resistance. Advances have been made in identifying and enriching CSC in leukemia and several solid tumors, including breast, brain and lung cancers. These studies suggest that, like no...

journal_title：Pediatric research

authors： Guo W,Lasky JL 3rd,Wu H

更新日期：2006-04-01 00:00:00

abstract：:Keratinocyte growth factor (KGF, or fibroblast growth factor 7) was previously reported to enhance the synthesis of surfactant in alveolar type II cells. We investigated the possible interactions between KGF and a glucocorticoid, dexamethasone (Dex), on surfactant protein (SP) gene expression. In cultured fetal rat ty...

journal_title：Pediatric research

authors： Mouhieddine-Gueddiche OB,Pinteur C,Chailley-Heu B,Barlier-Mur AM,Clement A,Bourbon JR

更新日期：2003-02-01 00:00:00

abstract：:Human autoimmune lymphoproliferative syndrome (ALPS) is caused by defective CD95-mediated apoptosis of lymphocytes. In most patients, heterozygous mutations within the CD95 gene are found. Mutated proteins interfere with CD95-signaling in a dominant-negative way. However, the penetrance of clinical disease is variable...

journal_title：Pediatric research

authors： Fuchs H,Posovszky C,Lahr G,van der Werff ten Bosch J,Boehler T,Debatin KM

更新日期：2009-02-01 00:00:00

abstract：:The ontogenetic renal responsiveness to exogenous cortisol was examined in the chronically cannulated ovine fetus. The contribution of effects at proximal and distal tubule of the kidney were studied also. Cortisol (81.5 micrograms/h) was infused into immature ovine fetuses (mean gestational age -113.9 days) on five o...

journal_title：Pediatric research

authors： Towstoless MK,McDougall JG,Wintour EM

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:To evaluate the apoptosis inhibitor of macrophage (AIM) deposition patterns on the kidneys of children with IgA nephropathy (IgAN) and Henoch-Schönlein purpura nephritis (HSPN) and to investigate the clinical usefulness of serum and/or urinary AIM levels as biomarkers for the disease activity. METHODS:Immun...

journal_title：Pediatric research

authors： Irabu H,Shimizu M,Kaneko S,Inoue N,Mizuta M,Tasaki Y,Ohta K,Yachie A,Wada T

更新日期：2020-05-14 00:00:00

abstract：:To investigate the functional maturity of the lungs of infants with pulmonary hypoplasia, we measured the expression of surfactant apoprotein-A (SP-A) in the autopsied lungs. Autopsied lungs were taken from 16 infants who died at birth or soon after. A lung-to-body weight ratio of less than 1.2% was defined as pulmona...

journal_title：Pediatric research

authors： Minowa H,Takahashi Y,Kawaguchi C,Sadou T,Konishi N,Nishikubo T,Yoshioka A

更新日期：2000-11-01 00:00:00

abstract：:In view of the suggested relationship between substrate availability, fetal growth and circulating fetal IGF-I concentrations, we investigated the effect of maternal starvation on plasma IGF-I levels in the late gestation ovine fetus. Ten fetuses aged 125-130 d gestation were sampled daily from indwelling arterial cat...

journal_title：Pediatric research

authors： Bassett NS,Oliver MH,Breier BH,Gluckman PD

更新日期：1990-04-01 00:00:00

abstract：:The response of cerebral blood volume (CBVR) to a small induced change in arterial carbon dioxide tension was studied by near-infrared spectroscopy in 17 newborn infants born from 26 wk of gestation to term. All 17 infants were undergoing mechanical ventilation but had apparently normal brains. The CBVR per kPa change...

journal_title：Pediatric research

authors： Wyatt JS,Edwards AD,Cope M,Delpy DT,McCormick DC,Potter A,Reynolds EO

更新日期：1991-06-01 00:00:00

abstract：:The fetal respiratory and electrocortical effects of thyrotropin-releasing hormone (TRH) administered into the lateral cerebral ventricles, have been investigated in chronically catheterized unanesthetized fetal sheep at 125-140 days of gestation. Stimulatory effects on fetal breathing movements were seen at doses as ...

journal_title：Pediatric research

authors： Bennet L,Gluckman PD,Johnston BM

更新日期：1988-01-01 00:00:00

abstract：:Intracellular levels of cysteine (CSH) and reduced glutathione (GSH) in the kidney and liver of rats from the newborn to the adult period have been determined using a sensitive high performance liquid chromatography method. In the kidney, the intracellular level of free CSH increased 4-fold from 1 to 4 nmol/mg protein...

journal_title：Pediatric research

authors： States B,Foreman JW,Segal S

更新日期：1987-11-01 00:00:00

abstract：:Previous studies have shown that early life stress in the form of intermittent maternal separation (MS) predisposes adult rats to develop stress-induced intestinal mucosal dysfunction and visceral hypersensitivity. However, the mechanism involved in the functional abnormalities is unclear. Our aim was to study immatur...

journal_title：Pediatric research

authors： Gareau MG,Jury J,Yang PC,MacQueen G,Perdue MH

更新日期：2006-01-01 00:00:00

abstract：:We investigated, using a human placental choriocarcinoma cell line as a model, the effects of the immunosuppressive drug cyclosporin A on several placental transport systems mediating the transfer of glucose and amino acids from mother to fetus. The results of the investigation show that the transport system responsib...

journal_title：Pediatric research

authors： Ramamoorthy S,Leibach FH,Mahesh VB,Ganapathy V

更新日期：1992-07-01 00:00:00

abstract：:Kawasaki disease, which is characterized by systemic vasculitis causing coronary arterial involvement in childhood, shows a variety of immunoregulatory abnormalities. Especially the direct or indirect deleterious effects on endothelial cells of cytokines and anti-endothelial cell antibodies (AECA) are considered to be...

journal_title：Pediatric research

authors： Sakata K,Kita M,Imanishi J,Onouchi Z,Liu Y,Mitsui Y

更新日期：1995-10-01 00:00:00

abstract：:The head sizes of 38 patients, growth hormone (GH) deficient following craniospinal (n = 26) or cranial irradiation (n = 12), have been assessed before (n = 38) and on completion of GH therapy (n = 15) or at the end of a similar period of observation without GH (n = 7). These results were compared to the change in hea...

journal_title：Pediatric research

authors： Clayton PE,Shalet SM,Price DA,Surtees RA,Pearson D

更新日期：1987-10-01 00:00:00

abstract：:Wu and colleagues analyzed the placental pathology from a subset of the neonates in the NEATO trial who had reports available and correlated the placental pathology findings with outcomes. This study highlights the importance of placental pathology, and its potential to bring precision medicine to critically-ill neona...

journal_title：Pediatric research

authors： Jantzie LL,Robinson S

更新日期：2020-04-01 00:00:00

abstract：:Newborn piglets exposed to acute hypoxia-ischemia (HI) received i.v. cannabidiol (HI + CBD) or vehicle (HI + VEH). In HI + VEH, 72 h post-HI brain activity as assessed by amplitude-integrated EEG (aEEG) had only recovered to 42 ± 9% of baseline, near-infrared spectroscopy (NIRS) parameters remained lower than normal, ...

journal_title：Pediatric research

authors： Lafuente H,Alvarez FJ,Pazos MR,Alvarez A,Rey-Santano MC,Mielgo V,Murgia-Esteve X,Hilario E,Martinez-Orgado J

更新日期：2011-09-01 00:00:00

abstract：:Neonatal jaundice is a common condition that could potentially lead to severe neurotoxicity. In this electrophysiological study we observed the effects of a short-term bilirubin injection on evoked potentials (population spike, PS) and long-term potentiation (LTP) in the hippocampal CA3 region of Sprague Dawley rats i...

journal_title：Pediatric research

authors： Zhang L,Liu W,Tanswell AK,Luo X

更新日期：2003-06-01 00:00:00

abstract：:To assess the National Institutes of Health extramural activity in the area of pediatric nephrology research, the rate of submission of grant applications to the National Institutes of Health and available indicators of the quality of these applications were analyzed. This was accomplished by utilizing the grant appli...

journal_title：Pediatric research

authors： Novello AC

更新日期：1985-11-01 00:00:00

abstract：:Rats were fed a 50% galactose diet during pregnancy and nursing, and the testes were later examined and hormone levels determined in male offspring. Exposure to galactose for various periods during pregnancy, throughout the entire gestation, or postnatally to nursing mother until pups were 5 wk of age produced no sign...

journal_title：Pediatric research

authors： Chen YT,Mattison DR,Bercu BB,Schulman JD

更新日期：1984-04-01 00:00:00

abstract：:The possible role played by albumin in regulating brain metabolism during development has been studied. The effects of fatty acid-free BSA on lactate, glucose, 3-hydroxybutyrate, and glutamine oxidation and lipogenesis by rat neurons and astrocytes from primary culture were studied. The rate of lactate oxidation and l...

journal_title：Pediatric research

authors： Vicario C,Tabernero A,Medina JM

更新日期：1993-12-01 00:00:00