Cysteine and glutathione levels in developing rat kidney and liver.

abstract：:Fetuin-A prevents tissue calcification by forming soluble complexes with calcium and phosphate. A pathological depletion of serum fetuin-A has been observed in children on dialysis or after renal transplantation but knowledge on physiologic age-related changes in serum fetuin-A is limited. We prospectively evaluated s...

journal_title：Pediatric research

authors： Häusler M,Schäfer C,Osterwinter C,Jahnen-Dechent W

更新日期：2009-12-01 00:00:00

abstract：:Vascular dopamine (DA1) receptors may modulate circulatory hemodynamics in lambs. We evaluated resting dopaminergic tone in lambs by pharmacologically manipulating peripheral DA1 receptors with i.v. SCH 23390, (a highly selective, competitive DA1 receptor antagonist) and i.v. fenoldopam, (a highly selective DA1 recept...

journal_title：Pediatric research

authors： Polak MJ,Drummond WH

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:This study aimed to assess cortical gray matter growth and maturation in neonates with congenital heart disease (CHD). METHODS:Thirty-one (near) term neonates with severe CHD (8 univentricular heart malformation (UVH), 21 d-transposition of great arteries (d-TGA) and 2 aortic coarctation) underwent cerebral...

journal_title：Pediatric research

authors： Claessens NH,Moeskops P,Buchmann A,Latal B,Knirsch W,Scheer I,Išgum I,de Vries LS,Benders MJ,von Rhein M

更新日期：2016-11-01 00:00:00

abstract：:Antigenic analysis of neuroblastoma cells was performed by autologous typing and indirect immunofluorescent test combined with absorption tests. Serum of a patient with neuroblastoma before treatment showed weak reactivity with cultured autologous neuroblastoma cells, while serum obtained from the same patient 3 month...

journal_title：Pediatric research

authors： Kawai K,Sakatoku H,Matsuda T,Kazuoka K,Kubo S,Kamiya H,Sakurai M

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:Current tools to predict the severity of respiratory syncytial virus (RSV) infection might be improved by including immunological parameters. We hypothesized that a combination of inflammatory markers would differentiate between severe and mild disease in RSV-infected children. METHODS:Blood and nasopharyng...

journal_title：Pediatric research

authors： Brand HK,Ferwerda G,Preijers F,de Groot R,Neeleman C,Staal FJ,Warris A,Hermans PW

更新日期：2013-02-01 00:00:00

abstract：:The neuroprotective effect of hypothermia instituted after resuscitation from asphyxic cardiac arrest has not been studied in immature brain, particularly in a large animal model with recovery periods greater than 4 d. Moreover, protection from severe hypoxia seen with 3 h of hypothermia was reported to be lost when h...

journal_title：Pediatric research

authors： Agnew DM,Koehler RC,Guerguerian AM,Shaffner DH,Traystman RJ,Martin LJ,Ichord RN

更新日期：2003-08-01 00:00:00

abstract：:Both severe impairments of brain development in untreated infants and acute reversible neurotoxic effects on brain function are clinical features of phenylketonuria (PKU). For determining whether impairments of cerebral energy metabolism play a role in the pathophysiology of PKU, quantitative in vivo 31P magnetic reso...

journal_title：Pediatric research

authors： Pietz J,Rupp A,Ebinger F,Rating D,Mayatepek E,Boesch C,Kreis R

更新日期：2003-04-01 00:00:00

abstract：:Many attempts have been made to obtain safe and effective analgesia in newborns. Oral glucose-water has been found to have analgesic properties in neonates. We investigated whether other sensory stimulation added to oral glucose provided more effective analgesia than oral glucose alone. In a randomized prospective dou...

journal_title：Pediatric research

authors： Bellieni CV,Bagnoli F,Perrone S,Nenci A,Cordelli DM,Fusi M,Ceccarelli S,Buonocore G

更新日期：2002-04-01 00:00:00

abstract：:Fetal lung cyclic AMP phosphodiesterase, cyclic AMP, phosphatidyl choline, and incorporation of precursors into phosphatidyl choline were measured in rabbits after maternal administration of hydrocortisone phosphate and aminophylline. Both agents inhibited lung phosphodiesterase activity and augmented cyclic AMP conce...

journal_title：Pediatric research

authors： Barrett CT,Sevanian A,Lavin N,Kaplan SA

更新日期：1976-06-01 00:00:00

abstract：:Based on the serum phenylalanine levels under free diet patients with hyperphenylalaninemia are classified as "classical" (>1200 micromol/L), "mild" (600-1200 micromol/L), or "non-phenylketonuria (PKU)-hyperphenylalaninemia" (<600 micromol/L). Recent studies revealed intellectual, neurologic, and neuropsychologic defi...

journal_title：Pediatric research

authors： Weglage J,Ullrich K,Pietsch M,Fünders B,Güttler F,Harms E

更新日期：1997-09-01 00:00:00

abstract：:Sparse-fur mice, 28 d of age with the x-chromosomal inherited defect of ornithine carbamoyltransferase, were used to investigate if tryptophan and the serotonin pathway in the brain are affected in this animal model which closely resembles the human inborn error of metabolism. Increased concentrations of tryptophan an...

journal_title：Pediatric research

authors： Bachmann C,Colombo JP

更新日期：1984-04-01 00:00:00

abstract：:We have previously discovered that the adult Drosophila melanogaster is tolerant to a low O2 environment, withstanding hours of total O2 deprivation without showing any evidence of cell injury. Subsequently, our laboratory embarked on the study of hypoxia tolerance using a mutagenesis and overexpression screens to beg...

journal_title：Pediatric research

authors： Zhou D,Visk DW,Haddad GG

更新日期：2009-09-01 00:00:00

abstract：:The factors that mediate the postnatal fall in pulmonary vascular resistance, which is crucial for normal gas exchange, are not fully understood. The endothelium has been implicated in this phenomenon, through the release of vasorelaxant factors such as nitric oxide (NO). Human pulmonary expression of endothelial NO s...

journal_title：Pediatric research

authors： Lévy M,Maurey C,Dinh-Xuan AT,Vouhé P,Israël-Biet D

更新日期：2005-05-01 00:00:00

abstract：:The purpose of this study was to begin to examine the influence of inhaled NO on O2 toxicity. The survival of Sprague-Dawley rats exposed to >95% O2, >95% O2 + 10 ppm NO, >95% O2 + 100 ppm NO, and >95% O2 + 3 ppm NO2 was determined. Survival at 120 h was 2/24 in >95% O2, 2/12 in >95% O2 + 10 ppm NO, and 1/12 in >95% O...

journal_title：Pediatric research

authors： Nelin LD,Welty SE,Morrisey JF,Gotuaco C,Dawson CA

更新日期：1998-06-01 00:00:00

abstract：:The short-term (0-48 h) effects of maternal betamethasone administration on computerized fetal heart rate (FHR) parameters were studied in 36 pregnancies at increased risk for preterm delivery. FHR was recorded for 90 min immediately before the start of betamethasone treatment and again at 6-h intervals during the nex...

journal_title：Pediatric research

authors： Lunshof MS,Boer K,Wolf H,Koppen S,Velderman JK,Mulder EJ

更新日期：2005-04-01 00:00:00

abstract：:Neonatal jaundice is a common condition that could potentially lead to severe neurotoxicity. In this electrophysiological study we observed the effects of a short-term bilirubin injection on evoked potentials (population spike, PS) and long-term potentiation (LTP) in the hippocampal CA3 region of Sprague Dawley rats i...

journal_title：Pediatric research

authors： Zhang L,Liu W,Tanswell AK,Luo X

更新日期：2003-06-01 00:00:00

abstract：:The major variation in effect between undiluted cystic fibrosis and heterozygote sera on rabbit tracheal epithelium was in terms of the time after exposure at which changes occurred. Exposure to both types of sera for 3 min caused release of goblet cell mucus and ciliary resorption possibly by apical swelling of colum...

journal_title：Pediatric research

authors： Kennedy JR,Allen PL

更新日期：1980-11-01 00:00:00

abstract：:The role of plasma glucose concentration in the regulation of endogenous glucose production in the human newborn was examined by infusing glucose at 2.6-4.6 mg/kg . min as a continuous infusion to eight normal term appropriate for gestational age infants, five preterm, and six small for gestational age infants. All in...

journal_title：Pediatric research

authors： Kalhan SC,Oliven A,King KC,Lucero C

更新日期：1986-01-01 00:00:00

abstract：:Tolazoline is used in neonatal intensive care to treat hypoxia secondary to persistent pulmonary hypertension of the newborn. Its use is often complicated by systemic hypotension. We compared the effect of tolazoline-induced hypotension on organ blood flow, regional brain blood flow, and cerebral metabolism in hypoxic...

journal_title：Pediatric research

authors： Balsan MJ,Cronin CM,Shaw MD,Milley JR

更新日期：1990-08-01 00:00:00

abstract：:In blood vessels with diameters less than 500 microns, both the hematocrit and viscosity decrease with decreasing tube diameter [Fåhraeus effect (FE) and Fåhraeus-Lindqvist effect (FLE)]. Because both effects may be influenced by red blood cell (RBC) volume and osmolality, the effects of RBC type and suspending medium...

journal_title：Pediatric research

authors： McKay CB,Linderkamp O,Meiselman HJ

更新日期：1993-10-01 00:00:00

abstract：:The association between lung injury and thrombocytopenia was investigated by comparing the megakaryocyte and platelet counts, and platelet activation using P-selectin as a marker, between the prepulmonary (right atrial) and postpulmonary (left atrial) blood in adult and neonatal (preterm and term) rats with and withou...

journal_title：Pediatric research

authors： Yang J,Yang M,Xu F,Li K,Lee SK,Ng PC,Tam JS,Yuen PM,Fok TF

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Using a large population-based sample, this study aims to verify whether televiewing at 29 mo, a common early childhood pastime, is prospectively associated with school readiness at 65 mo. METHODS:Participants are a prospective longitudinal cohort of 991 girls and 1,006 boys from the Quebec Longitudinal Stu...

journal_title：Pediatric research

authors： Pagani LS,Fitzpatrick C,Barnett TA

更新日期：2013-09-01 00:00:00

abstract：:The use of tissue engineering to develop new urinary bladder could have direct impact on children suffering from congenital bladder dysfunction. Current bladder tissue engineering protocols rely on scaffolds to support the ingrowth of new cells and the subsequent development of new tissues. The interaction between cel...

journal_title：Pediatric research

authors： Roth CC

更新日期：2010-05-01 00:00:00

abstract：:We studied the hemodynamic responses of 29 anesthetized and mechanically ventilated piglets to acute hypoxia [reduction of Pao2 from 130 to 38 mm Hg induced by inhalation of 7% fraction of inspired oxygen (Fio2) for 7.5 min] before and during group B beta-hemolytic streptococci (GBS) sepsis. During hypoxia, nonseptic ...

journal_title：Pediatric research

authors： Rudinsky B,Hipps R,Bell A,Lozon M,Meadow W

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:This study aimed to determine the prevalence of respiratory pathogens among newborns admitted to a neonatal medium care unit (NMCU) and to identify clinical predictors. METHODS:A 1-y observational study was performed of neonates admitted to an NMCU in Amsterdam, The Netherlands. Nasopharyngeal samples were ...

journal_title：Pediatric research

authors： Smit PM,Pronk SM,Kaandorp JC,Weijer O,Lauw FN,Smits PH,Claas EC,Mulder JW,Beijnen JH,Brandjes DP

更新日期：2013-03-01 00:00:00

abstract：:Medium chain acyl-CoA dehydrogenase deficiency (MCAD) is a defect in the mitochondrial oxidation of fatty acids. The disorder typically presents with episodes of vomiting and hypoglycemia, sometimes with changes in mental status and hepatic failure. These Reye's-like features may culminate in coma and death. Stress, i...

journal_title：Pediatric research

authors： Ziadeh R,Hoffman EP,Finegold DN,Hoop RC,Brackett JC,Strauss AW,Naylor EW

更新日期：1995-05-01 00:00:00

abstract：:The fetal brain develops rapidly during the last trimester of pregnancy. Therefore, the brain of infants who are born preterm is vulnerable to changes in oxygen and nutrient supply in the neonatal period. The objective was to determine the effect of gestational age (GA) on the cerebral O2 supply threshold level for pr...

journal_title：Pediatric research

authors： van Os S,Liem D,Hopman J,Klaessens J,van de Bor M

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Maternal smoking impairs fetal growth; however, if postnatal growth differs between children born small for gestational age (SGA) with smoking and non-smoking mother is unknown. METHODS:Cohort-study of term born children born appropriate for gestational age with non-smoking mother (AGA-NS, n = 30,561), SGA ...

journal_title：Pediatric research

authors： Lindström L,Wikström AK,Bergman E,Mulic-Lutvica A,Högberg U,Ahlsson F,Lundgren M

更新日期：2019-06-01 00:00:00

abstract：:Germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH) commonly affects premature neonates. The gravity of the consequences associated with GMH-IVH makes it a major concern in their care. GMH-IVH begins in the germinal matrix tissue and is, most commonly, the result of venous rupture. Arteriole-to-venous pre...

journal_title：Pediatric research

authors： Anstrom JA,Brown WR,Moody DM,Thore CR,Challa VR,Block SM

更新日期：2002-10-01 00:00:00

abstract：:Little is known about factors determining height outcome during GH treatment in Turner syndrome (TS). We investigated 987 TS children within the Kabi International Growth Study (KIGS) who had reached near adult height (NAH) after >4 y GH treatment (including >1 y before puberty). Through multiple regression analysis w...

journal_title：Pediatric research

authors： Ranke MB,Lindberg A,Ferrández Longás A,Darendeliler F,Albertsson-Wikland K,Dunger D,Cutfield WS,Tauber M,Wilton P,Wollmann HA,Reiter EO,KIGS International Board.

更新日期：2007-01-01 00:00:00