High-density lipoprotein subclass distribution in premature newborns before and after the onset of enteral feeding.

abstract：:Meconium aspiration syndrome (MAS) is a serious condition in newborns, associated with a poorly characterized inflammatory reaction. The aim of this study was to investigate a possible role for complement in pulmonary pathophysiology and systemic inflammation in experimental MAS. MAS was induced by instillation of mec...

journal_title：Pediatric research

authors： Lindenskov PH,Castellheim A,Aamodt G,Saugstad OD,Mollnes TE

更新日期：2004-11-01 00:00:00

abstract：:The use of tissue engineering to develop new urinary bladder could have direct impact on children suffering from congenital bladder dysfunction. Current bladder tissue engineering protocols rely on scaffolds to support the ingrowth of new cells and the subsequent development of new tissues. The interaction between cel...

journal_title：Pediatric research

authors： Roth CC

更新日期：2010-05-01 00:00:00

abstract：:This study determines the inotropic effects of prostaglandin D2 (PGD2) and prostaglandin E1 (PGE1) in the isolated, arterial perfused newborn (NB) and adult (A) rabbit heart. Significant positive inotropism of PGD2 was observed at all concentrations studied (1 X 10(-17) to 1 X 10(-7) M) in the two age groups; the effe...

journal_title：Pediatric research

authors： Uemura S,Nakanishi T,Matsuoka S,Friedman WF,Jarmakani JM

更新日期：1984-12-01 00:00:00

abstract：:Human GH is encoded by the GH-1 gene which belongs to the GH gene cluster encompassing a distance of about 65 kb on the long arm of chromosome 17. Familial isolated growth hormone deficiency (IGHD) is associated with at least four Mendelian disorders. These include two forms that have autosomal recessive inheritance (...

journal_title：Pediatric research

authors： Wagner JK,Eblé A,Hindmarsh PC,Mullis PE

更新日期：1998-01-01 00:00:00

abstract：:Spontaneous preterm birth is a serious and common pregnancy complication associated with hormonal dysregulation, infection, inflammation, immunity, rupture of fetal membranes, stress, bleeding, and uterine distention. Heredity is 25-40% and mostly involves the maternal genome, with contribution of the fetal genome. Si...

journal_title：Pediatric research

authors： Hallman M,Haapalainen A,Huusko JM,Karjalainen MK,Zhang G,Muglia LJ,Rämet M

更新日期：2019-03-01 00:00:00

abstract：:The effect of Cis-platin on the glomerular filtration rate and effective renal plasma flow was determined using a radioisotope clearance technique in young (3 wk old) and adult (more than 12 wk old) rats. Cis-platin was administered intravenously in dosages ranging from 2.5 to 10 mg/kg body weight, either as a single ...

journal_title：Pediatric research

authors： Jongejan HT,Provoost AP,Wolff ED,Molenaar JC

更新日期：1986-01-01 00:00:00

abstract：:Neutrophils contribute to ischemic brain injury in adult animals. The role of neutrophils in perinatal hypoxic-ischemic (HI) brain injury is unknown. Allopurinol reduces neutrophil accumulation after tissue ischemia and is protective against HI brain injury. This study was designed to investigate how neutrophils contr...

journal_title：Pediatric research

authors： Hudome S,Palmer C,Roberts RL,Mauger D,Housman C,Towfighi J

更新日期：1997-05-01 00:00:00

abstract：:Nasopharyngeal radium irradiation (NRI) was widely used from 1940 through 1970 to treat otitis serosa in children and barotrauma in airmen and submariners. We assessed whether NRI-exposed individuals were at higher risk for benign tumors, nonmelanoma skin cancer, thyroid disorders, and conditions related to regulatory...

journal_title：Pediatric research

authors： Ronckers CM,Land CE,Hayes RB,Verduijn PG,Stovall M,van Leeuwen FE

更新日期：2002-12-01 00:00:00

abstract：:Newborn rats exposed to 60% O(2) for 14 d demonstrated a bronchopulmonary dysplasia-like lung morphology and pulmonary hypertension. A 21-aminosteroid antioxidant, U74389G, attenuated both pulmonary hypertension and macrophage accumulation in the O(2)-exposed lungs. To determine whether macrophage accumulation played ...

journal_title：Pediatric research

authors： Jankov RP,Luo X,Belcastro R,Copland I,Frndova H,Lye SJ,Hoidal JR,Post M,Tanswell AK

更新日期：2001-08-01 00:00:00

abstract：:The effect of alpha-adrenergic blockade by phentolamine on the pulmonary vascular response to dopamine was studied in chronically prepared newborn lambs. Dopamine was administered at doses of 2.7 micrograms . kg-1 . min-1, 27 micrograms . kg-1 . min-1 and 270 micrograms . kg-1 . min-1 with and without alpha-adrenergic...

journal_title：Pediatric research

authors： Williams BJ,Drummond WH

更新日期：1983-06-01 00:00:00

abstract：:The gastrointestinal (GI) barrier function is immature in the preterm neonate and might thus facilitate translocation of enteric bacteria and gut-derived septicemia. Circumstantial evidence suggests that bacterial uptake from the intestine may be further enhanced by an alteration of the host nutritional status. To tes...

journal_title：Pediatric research

authors： Steinwender G,Schimpl G,Sixl B,Kerbler S,Ratschek M,Kilzer S,Hollwarth ME,Wenzl HH

更新日期：1996-03-01 00:00:00

abstract：:Little is known about factors determining height outcome during GH treatment in Turner syndrome (TS). We investigated 987 TS children within the Kabi International Growth Study (KIGS) who had reached near adult height (NAH) after >4 y GH treatment (including >1 y before puberty). Through multiple regression analysis w...

journal_title：Pediatric research

authors： Ranke MB,Lindberg A,Ferrández Longás A,Darendeliler F,Albertsson-Wikland K,Dunger D,Cutfield WS,Tauber M,Wilton P,Wollmann HA,Reiter EO,KIGS International Board.

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:To investigate whether the YAP/TAZ (Yes-associated protein/transcriptional coactivator with PDZ binding motif) pathway contributes to the pathogenesis of lymphatic malformations (LMs). METHODS:YAP, TAZ, CTGF (connective tissue growth factor), and Ki-67 were detected in LMs by immunohistochemistry. The coloc...

journal_title：Pediatric research

authors： Zhong W,Jiang H,Zou Y,Ren J,Li Z,He K,Zhao J,Zhou X,Mou D,Cai Y

更新日期：2020-04-12 00:00:00

abstract：:In artificial tubes as well as in blood vessels with diameters less than 500 microns, blood viscosity decreases with decreasing diameter (Fahraeus-Lindqvist effect). Our study measured viscosity of red blood cells (RBC) from 10 preterm infants, 10 term neonates, and 10 adults by means of a capillary viscometer. RBC we...

journal_title：Pediatric research

authors： Zilow EP,Linderkamp O

更新日期：1989-06-01 00:00:00

abstract：:Genetic factors cannot explain the recent rapid increase in the incidence of atopic diseases. The phenomenon has been explained by environmental factors, and there are data for and against the hypothesis that a decline in the pressure of microbial stimulation early in life could be behind the allergy epidemic. Changes...

journal_title：Pediatric research

authors： Kero J,Gissler M,Grönlund MM,Kero P,Koskinen P,Hemminki E,Isolauri E

更新日期：2002-07-01 00:00:00

abstract：:In dissociated whole brain cell cultures from newborn mice, we have previously shown that during glucose deprivation under normoxia, D-beta-hydroxybutyrate and oleic acid are increasingly used for energy production. We now asked whether this glucose dependency of the utilization of D-beta-hydroxybutyrate and oleic aci...

journal_title：Pediatric research

authors： Bossi E,Kohler E,Herschkowitz N

更新日期：1989-11-01 00:00:00

abstract：:Nitric oxide plays a major role in vascular tone control. Increased blood levels of bradykinin (BK), which stimulates nitric oxide biosynthesis, occur at birth. BK effects on ductus arteriosus (DA) tone were investigated in fetal rabbit under fetal (2.5% O2 "low PO2") and neonatal (30% O2 "high PO2") conditions using ...

journal_title：Pediatric research

authors： Bateson EA,Schulz R,Olley PM

更新日期：1999-04-01 00:00:00

abstract：:Phototherapy results in the conversion of native bilirubin to more water-soluble configurational and structural isomers. The serum half-life for the configurational isomer, the principal photoproduct in vivo, was determined by high pressure liquid chromatography in six premature infants following cessation of photothe...

journal_title：Pediatric research

authors： Ennever JF,Knox I,Denne SC,Speck WT

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Early identification of infants at risk for complications from patent ductus arteriosus (PDA) may improve treatment outcomes. The aim of this study was to identify biochemical markers associated with persistence of PDA, and with failure of pharmacological treatment for PDA, in extremely preterm infants. MET...

journal_title：Pediatric research

authors： Olsson KW,Larsson A,Jonzon A,Sindelar R

更新日期：2019-09-01 00:00:00

abstract：:BackgroundSotos syndrome (SoS) is an overgrowth disorder with various congenital anomalies and is usually accompanied by other clinical problems. However, anorectal malformations have not been documented as part of the SoS entity. Our objective is to report on a case of SoS associated with Hirschsprung's disease (HSCR...

journal_title：Pediatric research

authors： Sio CA,Jung K,Kim JH,Cheong HS,Shin E,Jang H,Yoon M,Jang H,Shin HD

更新日期：2017-07-01 00:00:00

abstract：:There are substantial alterations in fuel homeostasis immediately after birth. Leptin is a putative regulator of energy metabolism. Consequently, the aim of this study was to examine whether there are changes in circulating leptin concentrations during the early postnatal period. Umbilical cord mixed blood samples wer...

journal_title：Pediatric research

authors： Hytinantti T,Koistinen HA,Koivisto VA,Karonen SL,Andersson S

更新日期：1999-02-01 00:00:00

abstract：:Synchronized atrial contraction may be much more important in the newborn, who has a faster heart rate and a less compliant ventricle, than in the adult. We therefore investigated the extent by which synchronized atrioventricular contraction contributes to cardiac output and cardiac work in a neonatal circulation, and...

journal_title：Pediatric research

authors： Klautz RJ,Baan J,Teitel DF

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Earlier identification of children with prenatal alcohol exposure (PAE) remains a challenge. The objective of this study was to identify neurobehavioral (NB) outcomes associated with PAE in infants. METHODS:This manuscript evaluates NB outcomes at 6.33±1.12 months of age in 93 infants (39 PAE and 54 No-PAE)...

journal_title：Pediatric research

authors： Bakhireva LN,Lowe J,Garrison LM,Cano S,Leyva Y,Qeadan F,Stephen JM

更新日期：2018-09-01 00:00:00

abstract：:Sugar alcohols have been found to play an important osmoregulatory role both in unicellular organisms and, more recently, in multicellular organisms, including mammals. This study shows that myo-inositol accumulates in the brains of chronically hypernatremic mice, as had been earlier found in rats, and demonstrates fo...

journal_title：Pediatric research

authors： Thurston JH,Sherman WR,Hauhart RE,Kloepper RF

更新日期：1989-11-01 00:00:00

abstract：:Heme oxygenase (HO), the rate-limiting enzyme in the formation of bilirubin, is expressed in the lung and may serve as an antioxidant. This enzyme results in the formation of antioxidant bile pigments and the degradation of pro-oxidant heme. We wanted to evaluate the differences in expression of HO-1, the inducible fo...

journal_title：Pediatric research

authors： Dennery PA,Lee CS,Ford BS,Weng YH,Yang G,Rodgers PA

更新日期：2003-01-01 00:00:00

abstract：:The global burden of kidney disease is increasing, and several etiologies first begin in childhood. Risk factors for pediatric kidney disease are common in Africa, but data regarding its prevalence are lacking. We completed a systematic review of community-based studies describing the prevalence of proteinuria, hematu...

journal_title：Pediatric research

authors： Kayange NM,Smart LR,Tallman JE,Chu EY,Fitzgerald DW,Pain KJ,Peck RN

更新日期：2015-02-01 00:00:00

abstract：:Previous studies in adults have shown that chronic pulmonary hypertension is associated with decreased endothelial nitric oxide synthase (eNOS) expression in pulmonary arteries. However, the role of decreased eNOS expression in persistent pulmonary hypertension of the newborn (PPHN) is unknown. We investigated the hyp...

journal_title：Pediatric research

authors： Villanueva ME,Zaher FM,Svinarich DM,Konduri GG

更新日期：1998-09-01 00:00:00

abstract：:The mitochondria play a major role in the regulation of intracellular calcium. Despite the fact that the enterocytes receive the majority of absorbed calcium, the role of the intestinal mitochondria in calcium transport during maturation is not known. Therefore, the current studies were designed to characterize calciu...

journal_title：Pediatric research

authors： Kikuchi T,Kikuchi K,Arab N,Ghishan FK

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Phytosterols in soybean oil (SO) lipids likely contribute to parenteral nutrition-associated liver disease (PNALD) in infants. No characterization of phytosterol metabolism has been done in infants receiving SO lipids. METHODS:In a prospective cohort study, 45 neonates (36 SO lipid vs. 9 control) underwent ...

journal_title：Pediatric research

authors： Nghiem-Rao TH,Tunc I,Mavis AM,Cao Y,Polzin EM,Firary MF,Wang X,Simpson PM,Patel SB

更新日期：2015-08-01 00:00:00

abstract：:The copper concentrations in organs of developing Long-Evans Cinnamon (LEC) rats (2 d to 13 mo) were measured to elucidate the pathogenesis of their hereditary hepatitis. Hepatic copper contents of LEC rats were significantly higher than those of control rats (26 to 92 times higher). The subcellular distribution of he...

journal_title：Pediatric research

authors： Okayasu T,Tochimaru H,Hyuga T,Takahashi T,Takekoshi Y,Li Y,Togashi Y,Takeichi N,Kasai N,Arashima S

更新日期：1992-03-01 00:00:00