Kidney disease among children in sub-Saharan Africa: systematic review.

abstract：:Newly identified forms of electron transfer flavoprotein (ETF) deficiency in two patients with glutaric aciduria type II (GA II) were described. GA II has been attributed to a defect of either ETF or ETF dehydrogenase, resulting in multiple acyl-CoA dehydrogenation deficiency. ETF is a mitochondrial flavoprotein consi...

journal_title：Pediatric research

authors： Yamaguchi S,Orii T,Suzuki Y,Maeda K,Oshima M,Hashimoto T

更新日期：1991-01-01 00:00:00

abstract：:Serial plasma concentrations of immunoreactive 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), the stable hydration product of prostacyclin (PGI2), were measured with radioimmunoassay during the first month of life in 25 preterm infants with idiopathic respiratory distress syndrome (IRDS) and 38 preterm controls wi...

journal_title：Pediatric research

authors： Kääpä P,Koivisto M,Viinikka L,Ylikorkala O

更新日期：1982-10-01 00:00:00

abstract：:The hypoxanthine concentration in plasma was found to be a sensitive parameter of hypoxia of the fetus and the newborn infant. The plasma level of hypoxanthine in the umbilical cord in 29 newborn infants with normal delivery varied between 0 and 11.0 mumol/liter with a mean of 5.8 mumol/liter, SD 3.0 mumol/liter. Comp...

journal_title：Pediatric research

authors： Saugstad OD

更新日期：1975-04-01 00:00:00

abstract：:The use of tissue engineering to develop new urinary bladder could have direct impact on children suffering from congenital bladder dysfunction. Current bladder tissue engineering protocols rely on scaffolds to support the ingrowth of new cells and the subsequent development of new tissues. The interaction between cel...

journal_title：Pediatric research

authors： Roth CC

更新日期：2010-05-01 00:00:00

abstract：:Purified human liver arylsulfatase A on polyacrylamide gel electrophoresis at pH 4.0 is separated into two protein forms with enzymatic activity and two distinct inactive subunits. All of these components were immunologically distinguishable using different antisera preparations. In late infantile metachromatic leukod...

journal_title：Pediatric research

authors： Shapira E,DeGregorio RR,Nadler HL

更新日期：1978-03-01 00:00:00

abstract：:Previous studies have demonstrated that myocardial function changes during mammalian perinatal development. The purpose of this study was to evaluate the subcellular basis underlying the slower relaxation in the developing heart by examining perinatal changes in sarcoplasmic reticulum (SR) function, and in SR Ca2+ pum...

journal_title：Pediatric research

authors： Fisher DJ,Tate CA,Phillips S

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:In infants admitted to an ICU with respiratory failure, there is an association between the ratio of CD8+ to CD4+ T cells within the upper respiratory tract and disease severity. Whether this ratio is associated with respiratory disease severity within children presenting to a pediatric emergency department ...

journal_title：Pediatric research

authors： Cosgrove PR,Redhu NS,Tang Y,Monuteaux MC,Horwitz BH

更新日期：2021-01-27 00:00:00

abstract：:The uterus is unique among smooth muscular organs in that, during pregnancy, it undergoes profound, largely reversible, changes orchestrated by the ovarian hormones. These changes facilitate uterine adaptation to the stretch induced by the growing fetus such that a state of myometrial contractile quiescence can be mai...

journal_title：Pediatric research

authors： Riemer RK,Heymann MA

更新日期：1998-11-01 00:00:00

abstract：:Pediatric research may be entering a period of failure to thrive. This is despite impressive scientific achievements, significant financial benefits, intriguing unanswered questions and a rewarding life for the pediatric researcher. Many of the difficulties are financial and situational, including small departments an...

journal_title：Pediatric research

authors： Stiehm ER

更新日期：1985-06-01 00:00:00

abstract：:Critically ill infants are treated with dexamethasone (Dx) and other glucocorticoids to reduce inflammation and to promote lung and cardiac function. The neonatal immune system is immature, so neonatal dendritic cells (DCs) might be especially sensitive to glucocorticoid-mediated immunosuppression. To test this, we co...

journal_title：Pediatric research

authors： Mainali ES,Kikuchi T,Tew JG

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Neonates with hypoxic-ischemic encephalopathy (HIE) frequently develop acute kidney injury (AKI). Aminophylline has been shown to reduce severe renal dysfunction in neonates after perinatal asphyxia. However, the effect of aminophylline on renal function in neonates undergoing hypothermia has not been studie...

journal_title：Pediatric research

authors： Chock VY,Cho SH,Frymoyer A

更新日期：2020-06-05 00:00:00

abstract：BACKGROUND:Regular physical activity provides children with health and developmental benefits. This study investigated if active play and walking with the family dog was associated with better social-emotional development in young children. METHODS:We surveyed 1646 parents to ascertain if families with pre-schoolers o...

journal_title：Pediatric research

authors： Wenden EJ,Lester L,Zubrick SR,Ng M,Christian HE

更新日期：2020-07-06 00:00:00

abstract：:Beta cells are partially replaced in neonatal rodents after deletion with streptozotocin (STZ). Exposure of pregnant rats to a low protein (LP) diet impairs endocrine pancreas development in the offspring, leading to glucose intolerance in adulthood. Our objective was to determine whether protein restriction has a sim...

journal_title：Pediatric research

authors： Cox AR,Gottheil SK,Arany EJ,Hill DJ

更新日期：2010-07-01 00:00:00

abstract：:Prenatal exposure to infection and subsequent inflammatory responses have been implicated in the etiology of schizophrenia and autism. In this review, we summarize current evidence from human and animal studies supporting the hypothesis that the pathogenesis of these two disorders is linked via exposure to inflammatio...

journal_title：Pediatric research

authors： Meyer U,Feldon J,Dammann O

更新日期：2011-05-01 00:00:00

abstract：:We studied healthy and saline lavaged rabbits during high frequency oscillatory ventilation to determine what combination of frequency (f), tidal volume (Vt), and mean airway pressure (Paw) produced the lowest peak-to-peak alveolar pressure amplitude (Palv) and physiologic blood gas tensions. Sinusoidal volume changes...

journal_title：Pediatric research

authors： Kamitsuka MD,Boynton BR,Villanueva D,Vreeland PN,Frantz ID 3rd

更新日期：1990-01-01 00:00:00

abstract：:IL-8/CXC ligand (CXCL) 8 is ingested in high concentrations by the human fetus/neonate with amniotic fluid and human milk, and is also produced constitutively by intestinal epithelial cells (IEC). We have shown that recombinant human IL-8/CXCL8 (rhIL-8/CXCL8) protects cultured IEC against tumor necrosis factor (TNF)-a...

journal_title：Pediatric research

authors： Maheshwari A,Lacson A,Lu W,Fox SE,Barleycorn AA,Christensen RD,Calhoun DA

更新日期：2004-08-01 00:00:00

abstract：:BackgroundTo examine the mechanism of urethral seam formation during embryonal development of rat urethra.MethodsTime-mated Sprague-Dawley rats were killed and the genital tubercles of male pups harvested on embryonic day (ED) 15, 16, 18, and 19. External morphology was observed under scanning electron microscope. Ser...

journal_title：Pediatric research

authors： Zhou Y,Liu X,Huang F,Liu Y,Cao X,Shen L,Long C,He D,Lin T,Wei G

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Neonatal encephalopathy (NE) carries high risk for neurodevelopmental impairments. Therapeutic hypothermia (TH) reduces this risk, particularly for moderate encephalopathy (ME). Nevertheless, these infants often have subtle functional deficits, including abnormal memory function. Detection of deficits at the...

journal_title：Pediatric research

authors： Pfister KM,Zhang L,Miller NC,Hultgren S,Boys CJ,Georgieff MK

更新日期：2016-12-01 00:00:00

abstract：:Insulin administration is the primary therapy for type 1 diabetes mellitus (T1DM). Current available insulin therapies do not successfully enable children with T1DM to reach glycemic goals without side effects such as hypoglycemia and weight gain. Pramlintide is a synthetic analog of human amylin that acts in conjunct...

journal_title：Pediatric research

authors： Raman VS,Heptulla RA

更新日期：2009-04-01 00:00:00

abstract：:Energy and nitrogen balances were measured in growing low birthweight infants fed either mother's expressed breast milk or a 20 kcal per ounce formula to determine whether or not there were differences between the two dietary groups in (1) the partition of energy among excretion, expenditure, and storage and (2) the r...

journal_title：Pediatric research

authors： Whyte RK,Haslam R,Vlainic C,Shannon S,Samulski K,Campbell D,Bayley HS,Sinclair JC

更新日期：1983-11-01 00:00:00

abstract：:The ontogenetic renal responsiveness to exogenous cortisol was examined in the chronically cannulated ovine fetus. The contribution of effects at proximal and distal tubule of the kidney were studied also. Cortisol (81.5 micrograms/h) was infused into immature ovine fetuses (mean gestational age -113.9 days) on five o...

journal_title：Pediatric research

authors： Towstoless MK,McDougall JG,Wintour EM

更新日期：1989-07-01 00:00:00

abstract：:We examined the effect of inspiratory resistive loaded breathing (IRL) on the electromyographic (EMG) activity of the costal and crural diaphragm in nine anesthetized spontaneously breathing piglets (age 10-23 days, weight 2.8-4.4 kg). Bipolar wire electrodes were inserted into the anterior paratendinous costal diaphr...

journal_title：Pediatric research

authors： Watchko JF,Mayock DE,Standaert TA,Woodrum DE

更新日期：1987-01-01 00:00:00

abstract：:Sildenafil (Viagra) has been shown to be an effective pulmonary vasodilator and is increasingly used in patients with pulmonary hypertension. Its effects on the cerebral circulation are unclear and have not yet been described. We investigated the effect of i.v. sildenafil treatment on cerebral oxygenation in 13 childr...

journal_title：Pediatric research

authors： Nagdyman N,Fleck T,Bitterling B,Ewert P,Abdul-Khaliq H,Stiller B,Hübler M,Lange PE,Berger F,Schulze-Neick I

更新日期：2006-03-01 00:00:00

abstract：:D-myo-Inositol 1,4,5-triphosphate (IP3) is a key second messenger in many cells, including macrophages, T and B cells, and neutrophils, in which it regulates free intracellular calcium ion levels. In human polymorphonuclear leukocytes the rise of intracellular [Ca2+] is the signal that activates a number of functions ...

journal_title：Pediatric research

authors： Santoro P,Agosti V,Viggiano D,Palumbo A,Sarno T,Ciccimarra F

更新日期：1995-10-01 00:00:00

abstract：:Docosahexaenoic acid (DHA) is an omega-3 fatty acid that is highly concentrated in CNS tissues. Although breast milk contains the fatty acids DHA and arachidonic acid, infant formulas marketed in North America do not contain these nutrients. The potential deleterious effects of rearing infants with formulas devoid of ...

journal_title：Pediatric research

authors： Champoux M,Hibbeln JR,Shannon C,Majchrzak S,Suomi SJ,Salem N Jr,Higley JD

更新日期：2002-03-01 00:00:00

abstract：:Our objective was to determine the quantitative changes of individual triacylglycerol (TG) species in liver and carcass during early postnatal growth. Pregnant rats were killed at d 21 of pregnancy, and neonatal rats were killed at d 3 or 9 after birth. Quantitative changes in fatty acids and TG species of fetal/neona...

journal_title：Pediatric research

authors： Chen ZY,Cunnane SC

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:For the second aim of the Kellogg Foundation grant, this double-blind RCT investigated the impact of plasma vitamin D metabolite 25-hydroxyvitamin D (25(OH)D) on plasma immune-mediators during pregnancy. We hypothesized that higher 25(OH)D concentrations would associate with reduced pro-inflammatory and incr...

journal_title：Pediatric research

authors： Khatiwada A,Wolf BJ,Mulligan JK,Shary JR,Hewison M,Baatz JE,Newton DA,Hawrylowicz C,Hollis BW,Wagner CL

更新日期：2020-04-20 00:00:00

abstract：:Carbon monoxide (CO) and the excitatory amino acid glutamate both dilate cerebral arterioles in newborn pigs. The key enzyme in CO synthesis is heme oxygenase, which is highly expressed in neurons with glutamatergic receptor activity as well as cerebral microvessels. During seizures the extracellular level of glutamat...

journal_title：Pediatric research

authors： Pourcyrous M,Bada HS,Parfenova H,Daley ML,Korones SB,Leffler CW

更新日期：2002-05-01 00:00:00

abstract：:The proposed actions of atrial natriuretic factor (ANF) are mediated through specific plasma membrane (R1) receptors coupled to guanylate cyclase. A second receptor, R2, has been characterized by its ability to bind to an acyclic, truncated ANF analog (C-ANF4-23). The ANF-R2 receptor has not been identified in the fet...

journal_title：Pediatric research

authors： Castro R,Ervin MG,Leake RD,Ross MG,Fisher DA

更新日期：1991-04-01 00:00:00

abstract：:Plasma amino acid levels in newborn babies are often measured as part of a screening for inherited metabolic disease, or less commonly as part of a nutritional assessment. We have examined certain factors which affect the levels as measured in low birth weight babies during the first 3 wk of life. As in other studies,...

journal_title：Pediatric research

authors： Scott PH,Berger HM,Wharton BA

更新日期：1985-05-01 00:00:00