Multi-dimensional tumor detection in automated whole breast ultrasound using topographic watershed.

Abstract:

:Automated whole breast ultrasound (ABUS) is becoming a popular screening modality for whole breast examination. Compared to conventional handheld ultrasound, ABUS achieves operator-independent and is feasible for mass screening. However, reviewing hundreds of slices in an ABUS image volume is time-consuming. A computer-aided detection (CADe) system based on watershed transform was proposed in this study to accelerate the reviewing. The watershed transform was applied to gather similar tissues around local minima to be homogeneous regions. The likelihoods of being tumors of the regions were estimated using the quantitative morphology, intensity, and texture features in the 2-D/3-D false positive reduction (FPR). The collected database comprised 68 benign and 65 malignant tumors. As a result, the proposed system achieved sensitivities of 100% (133/133), 90% (121/133), and 80% (107/133) with FPs/pass of 9.44, 5.42, and 3.33, respectively. The figure of merit of the combination of three feature sets is 0.46 which is significantly better than that of other feature sets ( [Formula: see text]). In summary, the proposed CADe system based on the multi-dimensional FPR using the integrated feature set is promising in detecting tumors in ABUS images.

journal_name

IEEE Trans Med Imaging

authors

Lo CM,Chen RT,Chang YC,Yang YW,Hung MJ,Huang CS,Chang RF

doi

10.1109/TMI.2014.2315206

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

1503-11

issue

7

eissn

0278-0062

issn

1558-254X

journal_volume

33

pub_type

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