Abstract：
:Direct reconstruction of kinetic parameters from raw projection data is a challenging task in molecular imaging using dynamic positron emission tomography (PET). This paper presents a new optimization transfer algorithm for penalized likelihood direct reconstruction of nonlinear parametric images that is easy to use and has a fast convergence rate. Each iteration of the proposed algorithm can be implemented in three simple steps: a frame-by-frame maximum likelihood expectation-maximization (EM)-like image update, a frame-by-frame image smoothing, and a pixel-by-pixel time activity curve fitting. Computer simulation shows that the direct algorithm can achieve a better bias-variance performance than the indirect reconstruction algorithm. The convergence rate of the new algorithm is substantially faster than our previous algorithm that is based on a separable paraboloidal surrogate function. The proposed algorithm has been applied to real 4-D PET data.
journal_name
IEEE Trans Med Imagingjournal_title
IEEE transactions on medical imagingauthors
Wang G,Qi Jdoi
10.1109/TMI.2012.2212203subject
Has Abstractpub_date
2012-10-01 00:00:00pages
1977-88issue
10eissn
0278-0062issn
1558-254Xjournal_volume
31pub_type
杂志文章abstract：:The accurate determination of the local impulse response and the covariance in voxels from penalized maximum likelihood reconstructed images requires performing reconstructions from many noise realizations of the projection data. As this is usually a very time-consuming process, efficient analytical approximations bas...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2015.2410342
更新日期：2015-09-01 00:00:00
abstract：:To reconstruct electrical activity in the heart from body-surface electrocardiograms (ECGs) is an ill-posed inverse problem. Electrophysiological models have been found effective in regularizing these inverse problems by incorporating a priori knowledge about how the electrical potential in the heart propagates over t...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2906600
更新日期：2019-11-01 00:00:00
abstract：:This paper introduces and evaluates a block-iterative Fisher scoring (BFS) algorithm. The algorithm provides regularized estimation in tomographic models of projection data with Poisson variability. Regularization is achieved by penalized likelihood with a general quadratic penalty. Local convergence of the block-iter...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2008.918355
更新日期：2008-08-01 00:00:00
abstract：:Synthetic phased array (SPA) beamforming with Hadamard coding and aperture weighting is an optimal option for real-time volumetric imaging with a ring array, a particularly attractive geometry in intracardiac and intravascular applications. However, the imaging frame rate of this method is limited by the immense compu...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2013.2253117
更新日期：2013-07-01 00:00:00
abstract：:Motivated by the goals of improving detection of low-contrast and narrow vessels and eliminating false detections at nonvascular structures, a new technique is presented for extracting vessels in retinal images. The core of the technique is a new likelihood ratio test that combines matched-filter responses, confidence...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/tmi.2006.884190
更新日期：2006-12-01 00:00:00
abstract：:Advances in the area of digital chest radiography have resulted in the acquisition of high-quality images of the human chest. With these advances, there arises a genuine need for image processing algorithms specific to the chest, in order to fully exploit this digital technology. We have implemented the well-known tec...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.1987.4307791
更新日期：1987-01-01 00:00:00
abstract：:Coronary heart disease is a common cause of death despite being preventable. To treat the underlying plaque deposits in the arterial walls, intravascular optical coherence tomography can be used by experts to detect and characterize the lesions. In clinical routine, hundreds of images are acquired for each patient, wh...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2018.2865659
更新日期：2019-02-01 00:00:00
abstract：:The multi-channel nature of digital histopathological images presents an opportunity to exploit the correlated color channel information for better image modeling. Inspired by recent work in sparsity for single channel image classification, we propose a new simultaneous sparsity model for multi-channel histopathologic...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2014.2306173
更新日期：2014-05-01 00:00:00
abstract：:While plane-wave imaging can improve the performance of power Doppler by enabling much longer ensembles than systems using focused beams, the long-ensemble averaging of the zero-lag autocorrelation R(0) estimates does not directly decrease the mean noise level, but only decreases its variance. Spatial variation of the...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2017.2699672
更新日期：2017-09-01 00:00:00
abstract：:This paper presents a new approach to characterize subtle diffuse changes in multiple sclerosis (MS) using histograms derived from magnetization transfer ratio (MTR) images. Two major parts dominate our histogram analysis; 1) Classification of MTR histograms into control and MS subgroups; 2) Correlation with current d...
journal_title：IEEE transactions on medical imaging
pub_type： 临床试验,杂志文章
doi：10.1109/TMI.2002.1000256
更新日期：2002-04-01 00:00:00
abstract：:A technique determines the optimal window width for orbiting rod transmission studies in positron emission tomography (PET). Windowing reduces noise in orbiting rod transmission studies. Lines-of-response (LOR) which intersect the rods generate primarily true coincidence events. LOR which pass far from the rods genera...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.387708
更新日期：1995-01-01 00:00:00
abstract：:Complete projection (360 degrees ) free-space fluorescence tomography of opaque media is poised to enable 3-D imaging through entire small animals in vivo with improved depth resolution compared to 360 degrees -projection fiber-based systems or limited-view angle systems. This approach can lead to a new generation of ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2007.904662
更新日期：2008-02-01 00:00:00
abstract：:The aim of this study was to provide mathematical descriptors for the border of pigmented skin lesion images and to assess their efficacy for distinction among different lesion groups. New descriptors such as lesion slope and lesion slope regularity are introduced and mathematically defined. A new algorithm based on t...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2003.815901
更新日期：2003-08-01 00:00:00
abstract：:In the PET system a block detector, which is a position-sensitive photomultiplier (PMT) tube coupled to four arrays of 1.7-mm-wide BGO crystals, is utilized. Fifteen block detectors are positioned to form a 35-cm-diameter ring, with four BGO arrays coupled to each PMT. This provides four detector rings, giving the sys...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.192694
更新日期：1992-01-01 00:00:00
abstract：:The analysis of MR images is evolving from qualitative to quantitative. More and more, the question asked by clinicians is how much and where, rather than a simple statement on the presence or absence of abnormalities. The authors present a study in which the results obtained with a semiautomatic, multispectral segmen...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.363096
更新日期：1994-01-01 00:00:00
abstract：:An algorithm is developed that detects well-localized, unfragmented, thin edges in medical images based on optimization of edge configurations using a genetic algorithm (GA). Several enhancements were added to improve the performance of the algorithm over a traditional GA. The edge map is split into connected subregio...
journal_title：IEEE transactions on medical imaging
pub_type： 信件
doi：10.1109/42.712136
更新日期：1998-06-01 00:00:00
abstract：:Colorectal cancer can easily be prevented provided that the precursors to tumors, small colonic polyps, are detected and removed. Currently, the only definitive examination of the colon is fiber-optic colonoscopy, which is invasive and expensive. Computed tomographic colonography (CTC) is potentially a less costly and...
journal_title：IEEE transactions on medical imaging
pub_type： 临床试验,杂志文章
doi：10.1109/TMI.2002.806405
更新日期：2002-12-01 00:00:00
abstract：:Plane-wave-based ultrafast imaging has become the prevalent technique for non-conventional ultrasound imaging. The image quality, especially in terms of the suppression of artifacts, is generally compromised by reducing the number of transmissions for a higher frame rate. We hereby propose a new ultrafast imaging fram...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2017.2736423
更新日期：2018-02-01 00:00:00
abstract：:A big challenge in sensorless image-based ultrasound tracking is in the out-of-plane motion estimation. The correlation value of a specific model of speckle known as fully developed speckle (FDS) can be used to estimate the out-of-plane displacement. In real tissue, this kind of pattern is rare and the deviation of sp...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2013.2283969
更新日期：2014-01-01 00:00:00
abstract：:This paper examines the use of the algebraic reconstruction technique (ART) and related techniques to reconstruct 3-D objects from a relatively sparse set of cone-beam projections. Although ART has been widely used for cone-beam reconstruction of high-contrast objects, e.g., in computed angiography, the work presented...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.781017
更新日期：1999-06-01 00:00:00
abstract：:The hybrid magnetic resonance (MR)/X-ray suite (XMR) is a recently introduced imaging solution that provides new possibilities for guidance of cardiovascular catheterization procedures. We have previously described and validated a technique based on optical tracking to register MR and X-ray images obtained from the sl...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2005.856731
更新日期：2005-11-01 00:00:00
abstract：:Quantitative positron emission tomography (PET) imaging relies on accurate attenuation correction. Predicting attenuation values from magnetic resonance (MR) images is difficult because MR signals are related to proton density and relaxation properties of tissues. Here, we propose a method to derive the attenuation ma...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2012.2198831
更新日期：2012-09-01 00:00:00
abstract：:Tomographic reconstruction from positron emission tomography (PET) data is an ill-posed problem that requires regularization. An attractive approach is to impose an l(1) -regularization constraint, which favors sparse solutions in the wavelet domain. This can be achieved quite efficiently thanks to the iterative algor...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2008.923698
更新日期：2008-01-01 00:00:00
abstract：:This paper describes a new approach for texture characterization, based on nonseparable wavelet decomposition, and its application for the discrimination of visually similar diffuse diseases of liver. The proposed feature-extraction algorithm applies nonseparable quincunx wavelet transform and uses energies of the tra...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.730399
更新日期：1998-08-01 00:00:00
abstract：:Optical Diffusion Tomography (ODT) is a modern non-invasive medical imaging modality which requires mathematical modelling of near-infrared light propagation in tissue. Solving the ODT forward problem equation accurately and efficiently is crucial. Typically, the forward problem is represented by a Diffusion PDE and i...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2016.2641500
更新日期：2017-04-01 00:00:00
abstract：:An electrical impedance tomography (EIT) system that uses the optimal current method to inject currents and the regularized Newton-Raphson algorithm to reconstruct an image of resistivity distribution is discussed. Iterative methods to derive the optimal current patterns through iterative physical measurements are dev...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.192684
更新日期：1992-01-01 00:00:00
abstract：:Detecting tools in surgical videos is an important ingredient for context-aware computer-assisted surgical systems. To this end, we present a new surgical tool detection dataset and a method for joint tool detection and pose estimation in 2d images. Our two-stage pipeline is data-driven and relaxes strong assumptions ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2015.2450831
更新日期：2015-12-01 00:00:00
abstract：:To solve the problem that traditional image registration methods based on continuous optimization for large motion lung 4D CT image sequences are easy to fall into local optimal solutions and lead to serious misregistration, a novel image registration method based on high-order Markov Random Field (MRF) is proposed. B...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2937458
更新日期：2020-04-01 00:00:00
abstract：:Lung cancer is the leading cause of cancer deaths worldwide and early diagnosis of lung nodule is of great importance for therapeutic treatment and saving lives. Automated lung nodule analysis requires both accurate lung nodule benign-malignant classification and attribute score regression. However, this is quite chal...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2934577
更新日期：2020-03-01 00:00:00
abstract：:Cell segmentation and tracking in time-lapse fluorescence microscopy images is a task of fundamental importance in many biological studies on cell migration and proliferation. In recent years, level sets have been shown to provide a very appropriate framework for this purpose, as they are well suited to capture topolo...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2009.2038693
更新日期：2010-03-01 00:00:00
