Abstract:
:We propose an optimization algorithm to solve the brachytherapy seed localization problem in prostate brachytherapy. Our algorithm is based on novel geometric approaches to exploit the special structure of the problem and relies on a number of key observations which help us formulate the optimization problem as a minimization integer program (IP). Our IP model precisely defines the feasibility polyhedron for this problem using a polynomial number of half-spaces; the solution to its corresponding linear program is rounded to yield an integral solution to our task of determining correspondences between seeds in multiple projection images. The algorithm is efficient in theory as well as in practice and performs well on simulation data (approximately 98% accuracy) and real X-ray images (approximately 95% accuracy). We present in detail the underlying ideas and an extensive set of performance evaluations based on our implementation.
journal_name
IEEE Trans Med Imagingjournal_title
IEEE transactions on medical imagingauthors
Singh V,Mukherjee L,Xu J,Hoffmann KR,Dinu PM,Podgorsak Mdoi
10.1109/TMI.2007.900740subject
Has Abstractpub_date
2007-09-01 00:00:00pages
1291-304issue
9eissn
0278-0062issn
1558-254Xjournal_volume
26pub_type
杂志文章abstract::The solution of impedance distribution in electrical impedance tomography is a nonlinear inverse problem that requires the use of a regularization method. The generalized Tikhonov regularization methods have been popular in the solution of many inverse problems. The regularization matrices that are usually used with t...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.700740
更新日期:1998-04-01 00:00:00
abstract::Given that heart disease can cause abnormal motion dynamics over the cardiac cycle, understanding and quantifying cardiac motion can provide insight for clinicians to aid with diagnosis, therapy planning, and determining prognosis. The goal of this paper is to extract population-specific motion patterns from 3D displa...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2015.2405579
更新日期:2015-07-01 00:00:00
abstract::The authors present a new algorithmic procedure for the analysis of brain images. This procedure is specifically designed to image the activity and functional organization of the brain. The authors' results are tested on data collected and previously analyzed with the technique known as in vivo optical imaging of intr...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.414621
更新日期:1995-01-01 00:00:00
abstract::In this paper, we present a novel method for the correction of motion artifacts that are present in fetal magnetic resonance imaging (MRI) scans of the whole uterus. Contrary to current slice-to-volume registration (SVR) methods, requiring an inflexible anatomical enclosure of a single investigated organ, the proposed...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2017.2737081
更新日期:2017-10-01 00:00:00
abstract::Deformable image registration is an important tool in medical image analysis. In the case of lung computed tomography (CT) registration there are three major challenges: large motion of small features, sliding motions between organs, and changing image contrast due to compression. Recently, Markov random field (MRF)-b...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2013.2246577
更新日期:2013-07-01 00:00:00
abstract::For wrist complaints related to motion, a 2-D radiograph or CT scan of the static wrist may not always be considered diagnostic. 3-D motion imaging, i.e., multiple 3DCT scans in time (4DCT), enables quantifying carpal motion and comparing motion patterns of the affected wrist with those of the healthy contralateral si...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2018.2877503
更新日期:2019-04-01 00:00:00
abstract::In this paper, the accuracy of material decomposition (MD) using an energy discriminating photon counting detector was studied. An MD framework was established and validated using calcium hydroxyapatite (CaHA) inserts of known densities (50 mg/cm3, 100 mg/cm3, 250 mg/cm3, 400 mg/cm3), and diameters (1.2, 3.0, and 5.0 ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2019.2914370
更新日期:2020-01-01 00:00:00
abstract::High-resolution functional imaging of small animals is often obtained by single pinhole SPECT with circular orbit acquisition. Multipinhole SPECT adds information due to its improved sampling, and can improve the trade-off between resolution and sensitivity. To evaluate different pinhole collimator designs an efficien...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2007.902802
更新日期:2008-01-01 00:00:00
abstract::An overview of the Shinnar-Le Roux (SLR) algorithm is presented. It is shown how the performance of SLR pulses can be very accurately specified analytically. This reveals how to design a pulse that produces a specified slice profile and allows the pulse designer to trade off analytically the parameters describing the ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.75611
更新日期:1991-01-01 00:00:00
abstract::In this paper a psychophysical experiment and a multidimensional scaling (MDS) analysis are undergone to determine the physical characteristics that physicians employ to diagnose a burn depth. Subsequently, these characteristics are translated into mathematical features, correlated with these physical characteristics ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2013.2254719
更新日期:2013-06-01 00:00:00
abstract::A new reconstruction method, coined MIRAGE, is presented for accurate, fast, and robust parameter mapping of multiple-echo gradient-echo (MEGE) imaging, the basis sequence of novel quantitative magnetic resonance imaging techniques such as water content and susceptibility mapping. Assuming that the temporal signal can...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2017.2771504
更新日期:2018-02-01 00:00:00
abstract::Image-guided intervention for soft tissue organs depends on the accuracy of deformable registration methods to achieve effective results. While registration techniques based on elastic theory are prevalent, no methods yet exist that can prospectively estimate registration uncertainty to regulate sources and mitigate c...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2021.3052523
更新日期:2021-01-18 00:00:00
abstract::The identification of bronchi on Computed Tomography (CT) images of the lungs provides valuable clinical information in patients with suspected airways diseases including bronchiectasis, emphysema, or constrictive obliterative bronchiolitis. The automated recognition of the airways is, therefore, an important part of ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.952731
更新日期:2001-09-01 00:00:00
abstract::Computerized detection of clustered microcalcifications (MCs) in mammograms often suffers from the occurrence of false positives (FPs), which can vary greatly from case to case. We investigate how to apply statistical estimation to determine the number of FPs that are present in a detected MC lesion. First, we describ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2017.2654799
更新日期:2017-05-01 00:00:00
abstract::Magnetic particle imaging (MPI) is able to provide high temporal and good spatial resolution, high signal to noise ratio and sensitivity. Furthermore, it is a truly quantitative method as its signal strength is proportional to the concentration of its tracer, superparamagnetic iron oxide nanoparticles (SPIOs), over a ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2016.2559538
更新日期:2016-10-01 00:00:00
abstract::Arterial spin labeling (ASL) is an MRI perfusion imaging method from which quantitative cerebral blood flow (CBF) can be calculated. We present a multi-TI ASL method (multi-TI integrated ASL) in which variable post-labeling delays and variable TRs are used to improve the estimation of arterial transit time (ATT) and C...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2015.2395257
更新日期:2015-06-01 00:00:00
abstract::For fully characterizing renal cell carcinoma (RCC), information about the 3D tissue microstructure is essential. Histopathology, which represents the current diagnostic gold standard, is destructive and only provides 2D information. 3D X-ray histology endeavors to overcome these limitations by generating 3D data. In ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2019.2952028
更新日期:2020-05-01 00:00:00
abstract::The development and tests of an iterative reconstruction algorithm for emission tomography based on Bayesian statistical concepts are described. The algorithm uses the entropy of the generated image as a prior distribution, can be accelerated by the choice of an exponent, and converges uniformly to feasible images by ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.56340
更新日期:1990-01-01 00:00:00
abstract::We present a new method to automatically compute, reorient, and recenter the mid-sagittal plane in anatomical and functional three-dimensional (3-D) brain images. This iterative approach is composed of two steps. At first, given an initial guess of the mid-sagittal plane (generally, the central plane of the image grid...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.993131
更新日期:2002-02-01 00:00:00
abstract::We introduce an approach for image segmentation based on sparse correspondences between keypoints in testing and training images. Keypoints represent automatically identified distinctive image locations, where each keypoint correspondence suggests a transformation between images. We use these correspondences to transf...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2018.2851194
更新日期:2020-02-01 00:00:00
abstract::Regularization is desirable for image reconstruction in emission tomography. A powerful regularization method is the penalized-likelihood (PL) reconstruction algorithm (or equivalently, maximum a posteriori reconstruction), where the sum of the likelihood and a noise suppressing penalty term (or Bayesian prior) is opt...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2003.816960
更新日期:2003-09-01 00:00:00
abstract::Image segmentation is the partition of an image into a set of nonoverlapping regions whose union is the entire image. The image is decomposed into meaningful parts which are uniform with respect to certain characteristics, such as gray level or texture. In this paper, we propose a methodology for evaluating medical im...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.640755
更新日期:1997-10-01 00:00:00
abstract::Dynamic systems have proven to be well suited to describe a broad spectrum of human coordination behavior such synchronization with auditory stimuli. Simultaneous measurements of the spatiotemporal dynamics of electroencephalographic (EEG) and magnetoencephalographic (MEG) data reveals that the dynamics of the brain s...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2002.1009385
更新日期:2002-05-01 00:00:00
abstract::This paper addresses the long object problem in helical cone-beam computed tomography. We present the PHI-method, a new algorithm for the exact reconstruction of a region-of-interest (ROI) of a long object from axially truncated data extending only slightly beyond the ROI. The PHI-method is an extension of the Radon-m...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.870247
更新日期:2000-05-01 00:00:00
abstract::Radio-frequency (RF) transceiver array design using primary and higher order harmonics for in vivo parallel magnetic resonance imaging imaging (MRI) and spectroscopic imaging is proposed. The improved electromagnetic decoupling performance, unique magnetic field distributions and high-frequency operation capabilities ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2011.2166273
更新日期:2012-02-01 00:00:00
abstract::Reconstructing images of large high-contrast objects with microwave methods has proved difficult. Successful images have generally been obtained by using a priori information to constrain the image reconstruction to recover the correct electromagnetic property distribution. In these situations, the measured electric f...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.913177
更新日期:2001-02-01 00:00:00
abstract::Spectral computed tomography (CT) is a promising technique with the potential for improving lesion detection, tissue characterization, and material decomposition. In this paper, we are interested in kVp switching-based spectral CT that alternates distinct kVp X-ray transmissions during gantry rotation. This system can...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2014.2380993
更新日期:2015-03-01 00:00:00
abstract::Deep tissue injuries are subcutaneous regions of tissue breakdown associated with excessive mechanical pressure for extended period of time. These wounds are currently clinically undetectable in their early stages and result in severe burdens on not only the patients who suffer from them, but the health care system as...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2014.2313082
更新日期:2014-07-01 00:00:00
abstract::Cardiac resynchronization therapy (CRT) has been shown to improve cardiovascular function in specific patients suffering from heart failure. This procedure still needs to be optimized to overcome the high rate of implanted patients that do not respond to this therapy. We propose in this work a better characterization ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2014.2311694
更新日期:2014-06-01 00:00:00
abstract::X-ray computed tomography is a powerful medical imaging device. It allows high-resolution 3-D visualization of the human body. However, one drawback is the health risk associated with ionizing radiation. Simply downscaling the radiation intensities over the entire scan results in increased quantum noise. This paper pr...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2009.2034515
更新日期:2010-03-01 00:00:00