Abstract：
:Image textures in computed tomography colonography (CTC) have great potential for differentiating non-neoplastic from neoplastic polyps and thus can advance the current CTC detection-only paradigm to a new level with diagnostic capability. However, image textures are frequently compromised, particularly in low-dose CT imaging. Furthermore, texture feature extraction may vary, depending on the polyp spatial orientation variation, resulting in variable results. To address these issues, this study proposes an adaptive approach to extract and analyze the texture features for polyp differentiation. Firstly, derivative (e.g. gradient and curvature) operations are performed on the CT intensity image to amplify the textures with adequate noise control. Then Haralick co-occurrence matrix (CM) is used to calculate texture measures along each of the 13 directions (defined by the first and second order image voxel neighbors) through the polyp volume in the intensity, gradient and curvature images. Instead of taking the mean and range of each CM measure over the 13 directions as the so-called Haralick texture features, Karhunen-Loeve transform is performed to map the 13 directions into an orthogonal coordinate system so that the resulted texture features are less dependent on the polyp orientation variation. These simple ideas for amplifying textures and stabilizing spatial variation demonstrated a significant impact for the differentiating task by experiments using 384 polyp datasets, of which 52 are non-neoplastic polyps and the rest are neoplastic polyps. By the merit of area under the curve of receiver operating characteristic, the innovative ideas achieved differentiation capability of 0.8016, indicating the CTC diagnostic feasibility.
journal_name
IEEE Trans Med Imagingjournal_title
IEEE transactions on medical imagingauthors
Hu Y,Liang Z,Song B,Han H,Pickhardt PJ,Zhu W,Duan C,Zhang H,Barish MA,Lascarides CEdoi
10.1109/TMI.2016.2518958subject
Has Abstractpub_date
2016-06-01 00:00:00pages
1522-31issue
6eissn
0278-0062issn
1558-254Xjournal_volume
35pub_type
杂志文章abstract：:A common challenge when performing surface-based registration of images is ensuring that the surfaces accurately represent consistent anatomical boundaries. Image segmentation may be difficult in some regions due to either poor contrast, low slice resolution, or tissue ambiguities. To address this, we present a novel ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2015.2443978
更新日期：2015-12-01 00:00:00
abstract：:Optical Diffusion Tomography (ODT) is a modern non-invasive medical imaging modality which requires mathematical modelling of near-infrared light propagation in tissue. Solving the ODT forward problem equation accurately and efficiently is crucial. Typically, the forward problem is represented by a Diffusion PDE and i...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2016.2641500
更新日期：2017-04-01 00:00:00
abstract：:We present an integrated approach to probabilistic independent component analysis (ICA) for functional MRI (FMRI) data that allows for nonsquare mixing in the presence of Gaussian noise. In order to avoid overfitting, we employ objective estimation of the amount of Gaussian noise through Bayesian analysis of the true ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2003.822821
更新日期：2004-02-01 00:00:00
abstract：:The geometric component of the point spread function (PSF) of a gamma camera collimator can be determined analytically, and the penetration component can be calculated readily by numerical ray-tracing. A Monte Carlo simulation of photon transport which includes collimator scatter is developed. The simulation was imple...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.61758
更新日期：1990-01-01 00:00:00
abstract：:In routine oncologic positron emission tomography (PET), dynamic information is discarded by time-averaging the signal to produce static images of the "standardised uptake value" (SUV). Defining functional volumes of interest (VOIs) in terms of SUV is flawed, as values are affected by confounding factors and the chose...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2012.2193896
更新日期：2012-08-01 00:00:00
abstract：:Magnetic nanoparticles can be caused to oscillate under the influence of an incident ultrasonic wave. If the particles are momentarily aligned with a magnetizing pulse creating a macroscopic magnetization, this oscillation will result in a time-varying magnetic moment which should be detectable as an induced voltage i...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2007.895476
更新日期：2007-05-01 00:00:00
abstract：:We present a novel method to segment instances of glandular structures from colon histopathology images. We use a structure learning approach which represents local spatial configurations of class labels, capturing structural information normally ignored by sliding-window methods. This allows us to reveal different sp...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2017.2750210
更新日期：2018-01-01 00:00:00
abstract：:A minimalist numerical model of white matter is presented, the objective of which is to help provide a biological basis for improved diffusion tensor imaging (DTI) analysis. Water diffuses, relaxes, and exchanges in three compartments-intracellular, extracellular, and myelin sheath. Exchange between compartments is de...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2007.906787
更新日期：2007-11-01 00:00:00
abstract：:The maximum likelihood (ML) approach to estimating the radioactive distribution in the body cross section has become very popular among researchers in emission computed tomography (ECT) since it has been shown to provide very good images compared to those produced with the conventional filtered backprojection (FBP) al...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.538946
更新日期：1996-01-01 00:00:00
abstract：:Simulations provide a way of generating data where ground truth is known, enabling quantitative testing of image processing methods. In this paper, we present the construction of 20 realistic digital brain phantoms that can be used to simulate medical imaging data. The phantoms are made from 20 normal adults to take i...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2006.883453
更新日期：2006-11-01 00:00:00
abstract：:Iterative maximum likelihood (ML) transmission computed tomography algorithms have distinct advantages over Fourier-based reconstruction, but unfortunately require increased computation time. The convex algorithm [1] is a relatively fast iterative ML algorithm but it is nevertheless too slow for many applications. The...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.746730
更新日期：1998-12-01 00:00:00
abstract：:Multifrequency electrical impedance tomography (MFEIT) exploits the dependence of tissue impedance on frequency to recover an image of conductivity. MFEIT could provide emergency diagnosis of pathologies such as acute stroke, brain injury and breast cancer. We present a method for performing MFEIT using spectral const...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2013.2284966
更新日期：2014-02-01 00:00:00
abstract：:Radio-frequency (RF) transceiver array design using primary and higher order harmonics for in vivo parallel magnetic resonance imaging imaging (MRI) and spectroscopic imaging is proposed. The improved electromagnetic decoupling performance, unique magnetic field distributions and high-frequency operation capabilities ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2011.2166273
更新日期：2012-02-01 00:00:00
abstract：:An overview of the Shinnar-Le Roux (SLR) algorithm is presented. It is shown how the performance of SLR pulses can be very accurately specified analytically. This reveals how to design a pulse that produces a specified slice profile and allows the pulse designer to trade off analytically the parameters describing the ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.75611
更新日期：1991-01-01 00:00:00
abstract：:Multisource cone-beam computed tomography (CT) is an attractive approach of choice for superior temporal resolution, which is critically important for cardiac imaging and contrast enhanced studies. In this paper, we present a filtered-backprojection (FBP) algorithm for triple-source helical cone-beam CT. The algorithm...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2008.2004817
更新日期：2009-03-01 00:00:00
abstract：:Computerized detection of clustered microcalcifications (MCs) in mammograms often suffers from the occurrence of false positives (FPs), which can vary greatly from case to case. We investigate how to apply statistical estimation to determine the number of FPs that are present in a detected MC lesion. First, we describ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2017.2654799
更新日期：2017-05-01 00:00:00
abstract：:Coronary heart disease is a common cause of death despite being preventable. To treat the underlying plaque deposits in the arterial walls, intravascular optical coherence tomography can be used by experts to detect and characterize the lesions. In clinical routine, hundreds of images are acquired for each patient, wh...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2018.2865659
更新日期：2019-02-01 00:00:00
abstract：:Classical surgery is being overtaken by minimally invasive and transcatheter procedures. As there is no direct view or access to the affected anatomy, advanced imaging techniques such as 3D C-arm computed tomography (CT) and C-arm fluoroscopy are routinely used in clinical practice for intraoperative guidance. However...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2014.2343936
更新日期：2015-01-01 00:00:00
abstract：:Magnetic resonance imaging (MRI) pulse sequence consoles typically employ closed proprietary hardware, software, and interfaces, making difficult any adaptation for innovative experimental technology. Yet MRI systems research is trending to higher channel count receivers, transmitters, gradient/shims, and unique inter...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2011.2169681
更新日期：2012-02-01 00:00:00
abstract：:Electromagnetic brain imaging is the reconstruction of brain activity from non-invasive recordings of the magnetic fields and electric potentials. An enduring challenge in this imaging modality is estimating the number, location, and time course of sources, especially for the reconstruction of distributed brain source...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2932290
更新日期：2020-03-01 00:00:00
abstract：:Diffusion tensor imaging is widely used in brain connectivity research. As more and more studies recruit large numbers of subjects, it is important to design registration methods which are not only theoretically rigorous, but also computationally efficient. However, the requirement of reorienting diffusion tensors com...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2013.2274051
更新日期：2014-05-01 00:00:00
abstract：:A novel splat feature classification method is presented with application to retinal hemorrhage detection in fundus images. Reliable detection of retinal hemorrhages is important in the development of automated screening systems which can be translated into practice. Under our supervised approach, retinal color images...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2012.2227119
更新日期：2013-02-01 00:00:00
abstract：:Kidney stone disease is a major health problem worldwide. Shockwave lithotripsy (SWL), which uses high-energy shockwave pulses to break up kidney stones, is extensively used in clinic. However, despite its noninvasiveness, SWL can produce cavitation in vivo. The rapid expansion and violent collapse of cavitation bubbl...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2928740
更新日期：2020-02-01 00:00:00
abstract：:Convolutional neural networks (CNNs) have recently been used in biomedical imaging applications with great success. In this paper, we investigated the classi?cation performance of CNN models on diffusion weighted imaging (DWI) streamlines de?ned by functional MRI (fMRI) and electrical stimulation mapping (ESM). To lea...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2019.2902073
更新日期：2019-02-27 00:00:00
abstract：:Arterial spin labeling (ASL) is an MRI perfusion imaging method from which quantitative cerebral blood flow (CBF) can be calculated. We present a multi-TI ASL method (multi-TI integrated ASL) in which variable post-labeling delays and variable TRs are used to improve the estimation of arterial transit time (ATT) and C...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2015.2395257
更新日期：2015-06-01 00:00:00
abstract：:In this paper, we formulate a reconstruction algorithm for an n-Pi acquisition, where n can be any positive odd integer. The algorithm is a generalization of the method presented in (Bontus et al. 2003). It is based on the results obtained by Katsevich (2004). For the algorithm, different sets of filter-lines have to ...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2005.850545
更新日期：2005-08-01 00:00:00
abstract：:Studies reported in the literature indicate that breast cancer risk is associated with mammographic densities. An objective, repeatable, and a quantitative measure of risk derived from mammographic densities will be of considerable use in recommending alternative screening paradigms and/or preventive measures. However...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/42.938247
更新日期：2001-08-01 00:00:00
abstract：:We present a fast parallel algorithm to compute the nonequispaced fast Fourier transform on commodity graphics hardware (the GPU). We focus particularly on a novel implementation of the convolution step in the transform as it was previously its most time consuming part. We describe the performance for two common sampl...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/TMI.2007.909834
更新日期：2008-04-01 00:00:00
abstract：:We express the performance of the N-class "guessing" observer in terms of the N2-N conditional probabilities which make up an N-class receiver operating characteristic (ROC) space, in a formulation in which sensitivities are eliminated in constructing the ROC space (equivalent to using false-negative fraction and fals...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/tmi.2004.841227
更新日期：2005-03-01 00:00:00
abstract：:We propose a novel adaptive approach based on the Reproducing Kernel Particle Method (RKPM) to extract the cortical surfaces of the brain from three-dimensional (3-D) magnetic resonance images (MRIs). To formulate the discrete equations of the deformable model, a flexible particle shape function is employed in the Gal...
journal_title：IEEE transactions on medical imaging
pub_type： 杂志文章
doi：10.1109/tmi.2006.873614
更新日期：2006-06-01 00:00:00
