Dynamic metabolic changes after permanent cerebral ischemia in rats with/without post-stroke exercise: a positron emission tomography (PET) study.

abstract：BACKGROUND/AIMS:Both of neuromyelitis optica spectrum disease (NMOSDs) and idiopathic transverse myelitis (ITM) could present as acute transverse myelitis. However, long-term immunological treatment and prognosis are different for high recurrence of NMOSDs. In this study, we summarized clinical differences between acut...

journal_title：Neurological research

authors： Liu Z,Xie M,Lu Z,Zhang C,Chen H,Xu Y,Zhang M

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Progesterone modulates dopamine (DA) release in corpus striatum. Our objective was to evaluate the effect of the i.c.v injection of the neurosteroid allopregnanolone (ALL), a progesterone metabolite on dopaminergic activity in the corpus striatum of rats under different gonadal hormonal conditions. METHODS:...

journal_title：Neurological research

authors： Laconi MR,Reggiani PC,Penissi A,Yunes R,Cabrera RJ

更新日期：2007-09-01 00:00:00

abstract：:Advances in neuromodulation techniques offer the promise of new therapeutic interventions for patients with neuropsychiatric maladies. Several complex social, ethical and policy issues will attend developments in this area. In this paper an ethical framework for clinical research in interventional cognitive neuroscien...

journal_title：Neurological research

authors： Fins JJ

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Multiple sclerosis (MS) is a common inflammatory disease of the central nervous system. A contribution from complement has long been suspected. We investigated the association of complement factor H (CFH) Tyr402 His gene polymorphism and serum level in Egyptian patients with MS to examine whet...

journal_title：Neurological research

authors： Abdel Rasol HA,Helmy H,Aziz MA

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Intracranial artery stenosis may be the most frequent cause of ischemic stroke in the world. Early detection of asymptomatic intracranial artery stenosis may allow for therapeutic intervention. Most elements of the Framingham stroke risk profile (FSRP) are also risk factors for intracranial artery stenosis....

journal_title：Neurological research

authors： Zhang Y,Wu S,Jia Z,Zhou Y,Liu X,Wang W,Wang T,Wang L,Zhang S,Jin C,Zhao X

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Mapping of brain perfusion using bolus tracking methods is increasingly used to assess the amount and severity of cerebral ischemia in acute stroke. Using relative perfusion maps, however, it is difficult to identify the tissue at risk-maximum (TARM) of infarction with sufficient reliability and reproducibil...

journal_title：Neurological research

authors： Nabavi DG,Dittrich R,Kloska SP,Nam EM,Klotz E,Heindel W,Ringelstein EB

更新日期：2007-04-01 00:00:00

abstract：:Intraoperative use of somatosensory evoked potentials (SEP's) to monitor intracranial aneurysm surgery and flash visual evoked potentials (F-VEP's) for parasellar surgery have been routinely employed in our clinic. We found that both EP modalities are sensitive to the changing concentration of our standard hypotensive...

journal_title：Neurological research

authors： Wang AD,Costa e Silva I,Symon L,Jewkes D

更新日期：1985-06-01 00:00:00

abstract：OBJECTIVE:This review article summarizes in vitro, in vivo, and clinical evidence pertaining to temozolomide (TMZ) and bevacizumab (BEV) efficacy and mechanism of action in gliomas. METHODS:Relevant publications published before June 2013 in PubMed database were reviewed. RESULTS:Temozolomide and BEV are current chem...

journal_title：Neurological research

authors： Nanegrungsunk D,Onchan W,Chattipakorn N,Chattipakorn SC

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:To explore the risk factors for stroke-associated pneumonia (SAP). METHODS:A retrospective research study was carried out to investigate the clinical data of 1435 patients admitted to the neurological intensive care unit at our university hospital between 1 January 2000 and 31 December 2009. RESULTS:A multi...

journal_title：Neurological research

authors： Sui R,Zhang L

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:As a standard method, periodic limb movements in sleep (PLMS) are detected by means of polysomnography (PSG). Actigraphic detection of PLMS is a recently developed method for performing of multiple-night recordings in an outpatient setting. The aim of our study was to assess sensitivity-related parameters of ...

journal_title：Neurological research

authors： Kemlink D,Pretl M,Sonka K,Nevsimalova S

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:In the present study, we investigated the effects of treadmill exercise on microglial activation and the subsequent release of tumour necrosis factor-alpha (TNF-alpha), interleukin (IL)-6 and IL-1-beta in the hippocampus in a rat model of type 2 diabetes. METHODS:At 30 weeks of age, diabetic (Zucker diabeti...

journal_title：Neurological research

authors： Yoo DY,Chae J,Jung HY,Yim HS,Kim JW,Nam SM,Kim DW,Choi JH,Seong JK,Yoon YS,Hwang IK

更新日期：2015-08-01 00:00:00

abstract：:As early as 1 to 3 hr after cord transection, proliferation of many reactive oligodendrocytes was observed. Bundles of microfilaments and microtubules were observed in those cells that sent out long, complex pseudopodlike processes near the area of injury. These reactive oligodendrocytes may be comparable to Vaughn's ...

journal_title：Neurological research

authors： Chang LW,Kao CC

更新日期：1980-01-01 00:00:00

abstract：:Intracerebral hemorrhage (ICH) remains a major medical problem, for which there is no effective treatment. However, extensive experimental and clinical research carried out in recent years has brought to light new exciting ideas for novel potential treatments. First, it was well documented that the management of hyper...

journal_title：Neurological research

authors： Aronowski J,Hall CE

更新日期：2005-04-01 00:00:00

abstract：:Using the previously reported method of experimental localized brainstem infarct in dogs, we designed this study to elucidate sequential changes of regional cerebral blood flow (rCBF) in three separate regions of the central nervous system: the cerebral cortex, thalamus, and midbrain. The data obtained were referred t...

journal_title：Neurological research

authors： Matsumoto S,Kuwabara S,Moritake K

更新日期：2000-03-01 00:00:00

abstract：:In this study, we examined the degree of disruption of blood-brain barrier (BBB) in irradiated rat brains using P-glycoprotein, one of the functional molecules of BBB, as a marker. In the animal experiments, disruption of BBB has been mainly studied at the acute stage of brain edema caused by a lethal dose of irradiat...

journal_title：Neurological research

authors： Mima T,Toyonaga S,Mori K,Taniguchi T,Ogawa Y

更新日期：1999-03-01 00:00:00

abstract：:Recent studies suggest that high plasma levels of tissue-type plasminogen activator (tPA) and its inhibitor (plasminogen activator inhibitor-1, PAI-1) are markers of an increased risk of atherothrombotic ischemic events such as stroke and myocardial infarction. In this prospective study, we measured tPA antigen, PAI-1...

journal_title：Neurological research

authors： Zunker P,Schick A,Padró T,Kienast J,Phillips A,Ringelstein EB

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVES:To assess the prevalence of calcification surrounding the odontoid process (odontoid calcification) with crowned dens syndrome (CDS) and without CDS (non-CDS) and investigate factors that may related to the onset of CDS. METHODS:Retrospective review of consecutive patients visited Sir Run Run Shaw Hospital ...

journal_title：Neurological research

authors： Lu PL,Niu ZF,Qiu CW,Hu XY

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:Surgical management of tumors in the sacropelvic region is a challenging field of spine surgery because of the region's complex local anatomy and biomechanics. Recent developments in anesthesia and intensive care have allowed us to perform extended surgeries focused on the en bloc resection of sacropelvic tu...

journal_title：Neurological research

authors： Varga PP,Szoverfi Z,Lazary A

更新日期：2014-06-01 00:00:00

abstract：:The purpose of the present study was to examine the effect of nilvadipine (a dihydropyridine-type calcium entry blocker) on the cerebral circulation, experimental models of cerebral ischemia were used to measure abrupt changes in the cortical cerebral blood flow (CBF) at the 'penumbra' (the boundary region between the...

journal_title：Neurological research

authors： Tanaka R,Miyasaka Y,Maruyama S,Nagai S,Fujii K

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVES:In this study, we aimed to investigate the effect of bone mesenchymal stem cells (BMSCs) conditioned medium on BMP4-induced activation of the Smad signaling pathway during the process of neural stem cells differentiation. METHODS:We designed four experimental groups: (A) control group, (B) BMP-4 treatment g...

journal_title：Neurological research

authors： Fang H,Song P,Shen C,Liu X,Li H

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:To investigate risk factors for neurological complications after off-pump coronary artery bypass grafting (OPCABG). METHODS:We reviewed the cases of 813 patients who underwent OPCABG between August 2010 and September 2013.Data from preoperative 320 dynamic volume computed tomography (CT), CT angiography (CTA...

journal_title：Neurological research

authors： Xu B,Qiao Q,Chen M,Rastogi R,Luo D,Bi Q

更新日期：2015-05-01 00:00:00

abstract：:We examined antioxidant activity of cabergoline, a dopamine agonist, during the aerobic oxidation of phosphatidylcholine liposomes at 37 degrees C. Cabergoline retarded the oxidation initiated with a lipid-soluble initiator significantly better than that with a water-soluble initiator, suggesting that cabergoline loca...

journal_title：Neurological research

authors： Sohmiya M,Tanaka M,Okamoto K,Fujisawa A,Yamamoto Y

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:We sought to determine whether cerebral inflammation in ischemic rats was reduced by a neuroprotective action of pre-ischemic tumor necrosis factor-alpha up-regulation, which down-regulated matrix metalloproteinase-9 activity via extracellular signal-regulated kinase 1/2 phosphorylation. MATERIAL AND METHODS...

journal_title：Neurological research

authors： Curry A,Guo M,Patel R,Liebelt B,Sprague S,Lai Q,Zwagerman N,Cao FX,Jimenez D,Ding Y

更新日期：2010-09-01 00:00:00

abstract：:The goal of this paper is to provide scientists with a comprehensive review of the state-of-the-art influence the ischemic blood-brain barrier (BBB) has on the final development of Alzheimer's disease and to provide detailed food-for-thought which will hopefully stimulate more researchers in this area of neuroscience....

journal_title：Neurological research

authors： Pluta R

更新日期：2006-09-01 00:00:00

abstract：:At present, no practical method exists for monitoring the progression and severity of cerebral oedema in a clinical setting on a continuous basis. In search for such a method, we investigated the electrical characteristics of cerebral tissue at microwave frequencies to quantify cerebral oedema. The dielectric constant...

journal_title：Neurological research

authors： Kramer GG,Cardoso ER,Shwedyk E

更新日期：1992-06-01 00:00:00

abstract：:Tissue PCO2 (carbon dioxide tension) (PtCO2), interstitial H+ (H+e) and potassium activities (K+e) were monitored in the cerebral cortex of rats during and after 2-3 min of anoxia. Anoxia was associated with systemic hypotension and caused H+e (extracellular hydrogen ion activity) to increase from pH approximately equ...

journal_title：Neurological research

authors： Ohno M,Obrenovitch TP,Hartell N,Barratt S,Bachelard HS,Symon L

更新日期：1989-09-01 00:00:00

abstract：:The present study used immunohistochemistry to investigate p53 expression in rat brain following transient occlusion of the middle cerebral artery. In the control group, no p53-immunoreactive cells were found in any region of the central nervous system. P53 expression in reactive astrocytes was not obvious in the fore...

journal_title：Neurological research

authors： Chung YH,Shin CM,Kim MJ,Lee EY,Kim G,Cha CI

更新日期：2002-04-01 00:00:00

abstract：:In models of middle cerebral artery occlusion using intraluminal suture, the size and the distribution of ischemic injury vary considerably among laboratories. In transcranial models of cerebral ischemia, a more consistent cerebral ischemic lesion is seen in Spontaneously Hypertensive rats (SHR). In the present study,...

journal_title：Neurological research

authors： Dogan A,Başkaya MK,Rao VL,Rao AM,Dempsey RJ

更新日期：1998-04-01 00:00:00

abstract：:A simple and reproducible method of polymerase chain reaction (PCR) assay was established to detect trinucleotide repeat expansion for Huntington's disease (HD) using a new DNA polymerase and buffer system. The system consists of an extremely heat stable DNA polymerase (Pfu), and a buffer supplemented with ammonium su...

journal_title：Neurological research

authors： Watanabe M,Abe K,Aoki M,Kameya T,Itoyama Y,Shoji M,Ikeda M,Iizuka T,Hirai S

更新日期：1996-02-01 00:00:00

abstract：:The intracranial aneurysm, with an estimated occurrence of up to 4% in the general population, belongs among the most dangerous of cerebrovascular diseases. Although less than one-fifth of these cases results in a subarachnoid haemorrhage, the resulting disability and mortality rate is too high. More understanding is ...

journal_title：Neurological research

authors： Duros J,Clark ME,Kufahl RH,Nadvornik P

更新日期：1991-12-01 00:00:00