Different Ca2+ channels in soma and dendrites of hippocampal pyramidal neurons mediate spike-induced Ca2+ influx.

abstract：:The development of synaptic interconnections between the cerebellum and inferior olive, the sole source of climbing fibers, could contribute to the ontogeny of certain forms of motor learning (e.g., eyeblink conditioning). Purkinje cell complex spikes are produced exclusively by climbing fibers and exhibit short- and ...

journal_title：Journal of neurophysiology

authors： Nicholson DA,Freeman JH Jr

更新日期：2003-10-01 00:00:00

abstract：:We have examined the spatial integration properties of complex cells to determine whether some of their responses can be described by a maximum operation (MAX)-like computation, as suggested by Riesenhuber and Poggio's model of object recognition. Membrane potential was recorded from anesthetized cats while optimally ...

journal_title：Journal of neurophysiology

authors： Lampl I,Ferster D,Poggio T,Riesenhuber M

更新日期：2004-11-01 00:00:00

abstract：:Gain-of-function variants in voltage-gated sodium channel NaV1.7 that increase firing frequency and spontaneous firing of dorsal root ganglion (DRG) neurons have recently been identified in 5-10% of patients with idiopathic small fiber neuropathy (I-SFN). Our previous in vitro observations suggest that enhanced sodium...

journal_title：Journal of neurophysiology

authors： Lee SI,Hoeijmakers JGJ,Faber CG,Merkies ISJ,Lauria G,Waxman SG

更新日期：2020-02-01 00:00:00

abstract：:1. The effects of gamma-aminobutyric acid (GABA) and glycine and their respective antagonists were determined for neurons in the mouse superior olivary complex. Brain slices (400 microns) were cut in the frontal plane and maintained in an oxygenated saline solution for physiological recording. Recordings were made fro...

journal_title：Journal of neurophysiology

authors： Wu SH,Kelly JB

更新日期：1995-01-01 00:00:00

abstract：:Prominent arginine-vasopressin (AVP) binding and AVP V(1) type receptors are expressed early in the developing rat spinal cord. We sought to characterize their influence on neural excitability by using patch-clamp techniques to record AVP-induced responses from a population of motoneurons and interneurons in neonatal ...

journal_title：Journal of neurophysiology

authors： Oz M,Kolaj M,Renaud LP

更新日期：2001-09-01 00:00:00

abstract：:1. GABAergic mechanisms in the midbrain periaqueductal gray (PAG) have been proposed to control the activity of descending antinociceptive systems and defensive behavior. Here, the effect of neuronal disinhibition by gamma-aminobutyric acid (GABAA) receptor blockade at midbrain sites on spinal neuronal responses to no...

journal_title：Journal of neurophysiology

authors： Sandkühler J,Willmann E,Fu QG

更新日期：1991-01-01 00:00:00

abstract：:Trimming all but two whiskers in adult rats produces a predictable change in cortical cell-evoked responses characterized by increased responsiveness to the two intact whiskers and decreased responsiveness to the trimmed whiskers. This type of synaptic plasticity in rat somatic sensory cortex, called "whisker pairing ...

journal_title：Journal of neurophysiology

authors： Sachdev RN,Lu SM,Wiley RG,Ebner FF

更新日期：1998-06-01 00:00:00

abstract：:Peripheral denervation has been shown to cause reorganization of the deafferented somatotopic region in primary somatosensory cortex (S1). However, the basic mechanisms that underlie reorganization are not well understood. In the experiments described in this paper, a novel in vivo/in vitro preparation of adult rat S1...

journal_title：Journal of neurophysiology

authors： Hickmott PW,Merzenich MM

更新日期：2002-09-01 00:00:00

abstract：:In the absence of any obvious input, sensory neurons and interneurons can display resting or spontaneous activity. This is often regarded as noise and removed through trial averaging, although it may reflect history-dependent modulation of tuning or fidelity and, thus, be of functional relevance to downstream interneu...

journal_title：Journal of neurophysiology

authors： Lepreux G,Haupt SS,Dürr V

更新日期：2019-12-01 00:00:00

abstract：:1. The antidromic compound action potential (ACAP) of the auditory nerve was evoked by shocks to the auditory nerve root and recorded at the round window of the cochlea in anesthetized guinea pigs. The goal of this study was to determine the characteristics of the ACAP and compare these characteristics with those of t...

journal_title：Journal of neurophysiology

authors： Brown MC

更新日期：1994-05-01 00:00:00

abstract：:Humans and animals value the opportunity to choose by preferring alternatives that offer more rather than fewer choices. This preference for choice may arise not only from an increased probability of obtaining preferred outcomes but also from the freedom it provides. We used human neuroimaging to investigate the neura...

journal_title：Journal of neurophysiology

authors： Fujiwara J,Usui N,Park SQ,Williams T,Iijima T,Taira M,Tsutsui K,Tobler PN

更新日期：2013-10-01 00:00:00

abstract：:1. The graded, synaptic potentials of first-order visual interneurons (lamina monopolar cells) were examined with intracellular recordings. The spatiotemporal properties were characterized with drifting sine wave gratings and annuli. 2. Annulus-elicited inhibition is maximal for annulus-test pulse intervals of approxi...

journal_title：Journal of neurophysiology

authors： Glantz RM,Bartels A

更新日期：1994-06-01 00:00:00

abstract：:The retinal image of visual objects can vary drastically with changes of viewing angle. Nevertheless, our visual system is capable of recognizing objects fairly invariant of viewing angle. Under natural viewing conditions, different views of the same object tend to occur in temporal proximity, thereby generating tempo...

journal_title：Journal of neurophysiology

authors： Michler F,Eckhorn R,Wachtler T

更新日期：2009-08-01 00:00:00

abstract：:Previous studies have shown that regional slow-wave activity (SWA) during non-rapid eye movement (NREM) sleep is modulated by prior experience and learning. Although this effect has been convincingly demonstrated for the sensorimotor domain, attempts to extend these findings to the visual system have provided mixed re...

journal_title：Journal of neurophysiology

authors： Bernardi G,Betta M,Cataldi J,Leo A,Haba-Rubio J,Heinzer R,Cirelli C,Tononi G,Pietrini P,Ricciardi E,Siclari F

更新日期：2019-06-01 00:00:00

abstract：:Self-motion generates patterns of optic flow on the retina. Neurons in the dorsal part of the medial superior temporal area (MSTd) are selective for these optic flow patterns. It has been shown that neurons in this area that are selective for expanding optic flow fields are involved in heading judgments. We wondered h...

journal_title：Journal of neurophysiology

authors： Xu H,Wallisch P,Bradley DC

更新日期：2014-06-01 00:00:00

abstract：:1. Using patch-clamp methods, we show that brief prepulses to very positive voltages increase (facilitate) the amplitude of current through Ca2+ channels during a subsequent test pulse in some, but not all, dorsal root ganglion (DRG) sensory neurons. The amplitude of this facilitated current generally increases when t...

journal_title：Journal of neurophysiology

authors： Womack MD,McCleskey EW

更新日期：1995-05-01 00:00:00

abstract：:Certain hand-held tools alter the mapping between hand motion and motion of the tool end point that must be controlled in order to perform a task. For example, when using a pool cue, the motion of the cue tip is reversed relative to the hand. Previous studies have shown that the time required to initiate a reaching mo...

journal_title：Journal of neurophysiology

authors： Baugh LA,Hoe E,Flanagan JR

更新日期：2012-10-01 00:00:00

abstract：:1. Two hundred and twenty-one spinothalamic tract (STT) neurons in the lumbar spinal cord of anesthetized monkeys were studied. The majority of the recordings were in laminae IV-VI. Thirteen of these neurons were intracellularly injected with horseradish peroxidase and histologically reconstructed. 2. A standard serie...

journal_title：Journal of neurophysiology

authors： Surmeier DJ,Honda CN,Willis WD Jr

更新日期：1988-03-01 00:00:00

abstract：:Top-down selective attention to the affective properties of taste stimuli increases activation to the taste stimuli in the orbitofrontal cortex (OFC) and pregenual cingulate cortex (PGC), and selective attention to the intensity of the stimuli increases the activation in the insular taste cortex, but the origin of the...

journal_title：Journal of neurophysiology

authors： Grabenhorst F,Rolls ET

更新日期：2010-09-01 00:00:00

abstract：:Although previous research with human and nonhuman primates has examined the neural correlates of performance monitoring, discrepancies in methodology have limited our ability to make cross-species generalizations. One major obstacle arises from the use of different behavioral responses and tasks across different prim...

journal_title：Journal of neurophysiology

authors： Reinhart RM,Carlisle NB,Kang MS,Woodman GF

更新日期：2012-05-01 00:00:00

abstract：:Gain-of-function missense mutations in voltage-gated sodium channel Nav1.7 have been linked to small-fiber neuropathy, which is characterized by burning pain, dysautonomia and a loss of intraepidermal nerve fibers. However, the mechanistic cascades linking Nav1.7 mutations to axonal degeneration are incompletely under...

journal_title：Journal of neurophysiology

authors： Estacion M,Vohra BP,Liu S,Hoeijmakers J,Faber CG,Merkies IS,Lauria G,Black JA,Waxman SG

更新日期：2015-09-01 00:00:00

abstract：:An imbalance between the strengths of excitatory and inhibitory synaptic inputs has been proposed as the cellular basis of autism and related neurodevelopmental disorders. Previous studies examining spontaneous levels of excitatory and inhibitory neurotransmission in the forebrain regions of methyl-CpG-binding protein...

journal_title：Journal of neurophysiology

authors： Nelson ED,Bal M,Kavalali ET,Monteggia LM

更新日期：2011-07-01 00:00:00

abstract：:1. Monkeys were trained to react to an arm perturbation according to an instruction delivered prior to the perturbation. There were two possible instructions (push or pull), and monkeys learned to respond accordingly regardless of the direction (push or pull) of the triggering perturbation. 2. Pyramidal tract neurons ...

journal_title：Journal of neurophysiology

authors： Evarts EV,Tanji J

更新日期：1976-09-01 00:00:00

abstract：:We have characterized selectivity and sparseness in anterior inferotemporal cortex, using a large data set. Responses were collected from 674 monkey inferotemporal cells, each stimulated by 806 object photographs. This 806 × 674 matrix was examined in two ways: columnwise, looking at responses of a single neuron to al...

journal_title：Journal of neurophysiology

authors： Lehky SR,Kiani R,Esteky H,Tanaka K

更新日期：2011-09-01 00:00:00

abstract：:Some neurons in early visual cortex are highly selective for the position of oriented edges in their receptive fields (simple cells), whereas others are largely position insensitive (complex cells). These characteristics are reflected in their sensitivity to the spatial phase of moving sine-wave gratings: simple cell ...

journal_title：Journal of neurophysiology

authors： Cloherty SL,Ibbotson MR

更新日期：2015-01-15 00:00:00

abstract：:Eigenmannia, a genus of weakly electric fish, exhibits a specialized behavior known as the jamming avoidance response (JAR). The JAR results in a categorical difference between Eigenmannia that are in groups of conspecifics and those that are alone. Fish in groups exhibit the JAR behavior and thereby experience ongoin...

journal_title：Journal of neurophysiology

authors： Ramcharitar JU,Tan EW,Fortune ES

更新日期：2006-11-01 00:00:00

abstract：:The noted disruption of thalamocortical connections and abnormalities in tactile sensory function has resulted in a new definition of cerebral palsy (CP) that recognizes the sensorimotor integration process as central to the motor impairments seen in these children. Despite this updated definition, the connection betw...

journal_title：Journal of neurophysiology

authors： Kurz MJ,Heinrichs-Graham E,Becker KM,Wilson TW

更新日期：2015-05-01 00:00:00

abstract：:Cold-sensitive and nociceptive neural pathways interact to shape the quality and intensity of thermal and pain perception. Yet the central processing of cold thermosensation in the human brain has not been extensively studied. Here, we used magnetoencephalography and EEG in healthy volunteers to investigate the time c...

journal_title：Journal of neurophysiology

authors： Fardo F,Vinding MC,Allen M,Jensen TS,Finnerup NB

更新日期：2017-05-01 00:00:00

abstract：:While the effects of sensory feedback on bimanual tasks have been studied extensively at two ends of the motor control hierarchy, the cortical and behavioral levels, much less is known about how it affects the intermediate levels, including neural control of homologous muscle groups. We investigated the effects of som...

journal_title：Journal of neurophysiology

authors： Nguyen HB,Lee SW,Harris-Love ML,Lum PS

更新日期：2017-02-01 00:00:00

abstract：:Several identified neurons of the Aplysia buccal ganglia respond to choline. Iontophoretic applications of either choline or acetylcholine (ACh) to voltage-clamped inhibitory follower neurons produce similar currents. Peak amplitudes of choline responses were 10-100% of ACh responses on the same cell. Choline currents...

journal_title：Journal of neurophysiology

authors： Gardner D,Ruff RL,White RL

更新日期：1984-01-01 00:00:00