Abstract：
INTRODUCTION:Although smoking cessation is strongly indicated by international guidelines as an effective therapeutic tool for patients with COPD and Asthma, a large proportion of them do not quit smoking and they are regarded as a "difficult" target group. AIM:To study the effectiveness of an intensive smoking cessation program in smokers with COPD and asthma under real-life conditions. METHODS:166 smokers with COPD, 120 smokers with asthma and 1854 control smokers attended the smoking cessation program in the out-patient patient Smoking Cessation Clinic of the Pulmonary Department in Athens University. Continuous Abstinence Rate (CAR) was evaluated in 3, 6, 9 and 12 months after the target quit date. RESULTS:Short-term CAR (in 3 months) was 49.4% for COPD smokers, 51.7% for asthmatic smokers and 48.0% for the control group of smokers. 12 months after the initial visit the CAR was 13.9%, 18.3% and 15.9%, respectively. No statistically significant differences between groups at any study period were found. Smokers with good compliance with the program had higher long-term CAR after 12 months: 37.7% in COPD smokers, 40.0% in asthmatic smokers and 39.3% in control smokers. High CAR was observed at all stages of COPD severity. CONCLUSION:The results support the view that smokers with respiratory obstructive airway diseases of any severity should be offered an intensive smoking cessation program with regular and long-term follow-up. This will help them to achieve high abstinence rates and prevent relapses.
journal_name
Respir Medjournal_title
Respiratory medicineauthors
Gratziou Ch,Florou A,Ischaki E,Eleftheriou K,Sachlas A,Bersimis S,Zakynthinos Sdoi
10.1016/j.rmed.2014.01.007subject
Has Abstractpub_date
2014-04-01 00:00:00pages
577-83issue
4eissn
0954-6111issn
1532-3064pii
S0954-6111(14)00030-4journal_volume
108pub_type
杂志文章abstract：RATIONALE:Asthma is a heterogeneous disease, and a great majority of pediatric patients with asthma demonstrate atopic characteristics and develop a Th2 type cytokine response. Nonatopic asthma, on the other hand, is seen more rarely. METHODS:In this study, levels of IL-5, IL-8 and MMP-9 were measured in exhaled breat...
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pub_type： 临床试验,杂志文章,随机对照试验
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pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2012-12-01 00:00:00
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pub_type： 杂志文章,随机对照试验
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pub_type： 杂志文章,多中心研究
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更新日期：2007-02-01 00:00:00
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pub_type： 杂志文章,meta分析
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更新日期：2001-08-01 00:00:00
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更新日期：2006-05-01 00:00:00
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更新日期：2004-01-01 00:00:00
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更新日期：2010-09-01 00:00:00
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更新日期：2008-09-01 00:00:00
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更新日期：2019-05-01 00:00:00
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更新日期：2007-10-01 00:00:00
