Seroconversion to human immunodeficiency virus (HIV) in persons attending an STD clinic in Copenhagen.

Abstract:

:1,182 males and 155 females attending an STD clinic from June 1984 to October 1985 were investigated for the presence of antibodies to human immunodeficiency virus (HIV). 348 (29.5%) of the males and 5 (3.2%) of the females were antibody positive (ab+). 237 of the males were initially antibody negative (ab-) and were tested more than once, and during a 16-month period 40 of these seroconverted from ab- to antibody positive. The mean follow-up period of these 40 patients was 7.1 months, and thus the seroconversion rate is estimated to be 2.4% per month. Samples from 37 of these were available for HIV antigen testing. 19 of the patients were antigen positive in the latest ab- sample and accordingly, 18 patients were antigen negative in the latest ab- sample. No difference was found between the mean follow-up periods of those with and those without HIV antigen in the latest ab- serum and the presence of HIV antigen in serum was not associated with symptoms of acute HIV infection. After 20 months of follow-up, none (0.0-8.8%, 97.5% confidence limits) of the 40 patients have developed AIDS or AIDS-related complex.

journal_name

Acta Derm Venereol

authors

Lindhardt BO,Ulrich K,Sindrup JH,Avnstorp C,Fogh H,Wantzin GL

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

250-3

issue

3

eissn

0001-5555

issn

1651-2057

journal_volume

68

pub_type

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