Contact allergy to gold and gold therapy in patients with rheumatoid arthritis.

Abstract:

:Patients with rheumatoid arthritis were investigated for contact allergy to gold in connection with treatment with gold preparations. There were 57 patients with rheumatoid arthritis previously treated with gold, with or without cutaneous side-effects, as well as 20 patients intended for such treatment; all were exposed to patch and intradermal tests with gold sodium thiosulfate, gold sodium thiomalate and auranofin. Contact allergy to gold was demonstrated in 8 out of 77 patients (10.4%). In the retrospective material, gold allergy was found in 1.8%, in the prospective material in 35.0%. Contact allergy to gold is very frequent among patients with rheumatoid arthritis before gold therapy. In order to avoid early hypersensitivity reactions skin tests should be carried out before gold therapy is instituted.

journal_name

Acta Derm Venereol

authors

Möller H,Svensson A,Björkner B,Bruze M,Lindroth Y,Manthorpe R,Theander J

doi

10.2340/0001555577370373

subject

Has Abstract

pub_date

1997-09-01 00:00:00

pages

370-3

issue

5

eissn

0001-5555

issn

1651-2057

journal_volume

77

pub_type

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