Effect of EMLA cream on skin thickness and subcutaneous venous diameter. A randomized, placebo-controlled study in children.

Abstract:

:EMLA cream, which is used to provide analgesia prior to venepuncture, induces a skin-blanching reaction. This reaction may be caused by both skin hydration and vasoconstriction. Twenty healthy children with veins suitable for venepuncture on the dorsa of the hands or at the antecubital fossae had applied either EMLA cream or placebo cream under occlusion for 60-70 min in a randomized, double-blind, cross-over study. An ultrasound examination of the skin was conducted. The mean percentage change in vein diameter after removal of EMLA cream was not significant whereas, 15 min after EMLA cream removal, the decrease in the initial vein diameter (13.5%) was significant (p<0.01). The mean percent increase in skin thickness after the removal of EMLA cream was also significant (19.3%; p=0.01). The changes in vein diameter and skin thickness due to the application of EMLA cream do not seem to be of clinical importance to vein cannulation.

journal_name

Acta Derm Venereol

authors

Egekvist H,Bjerring P

doi

10.1080/000155500459268

subject

Has Abstract

pub_date

2000-09-01 00:00:00

pages

340-3

issue

5

eissn

0001-5555

issn

1651-2057

journal_volume

80

pub_type

临床试验,杂志文章,随机对照试验
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    authors: Hjorth N,Madsen K,Nørgaard M

    更新日期:1986-01-01 00:00:00

  • Subclinical joint involvement in psoriasis: magnetic resonance imaging and X-ray findings.

    abstract::Previous studies have shown that magnetic resonance imaging is more sensitive in assessing soft tissue and bone involvement in inflammatory arthritis than conventional radiography. Therefore the main objects of this study were to evaluate the frequency of hand involvement in psoriatic patients free from arthritic symp...

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    pub_type: 杂志文章

    doi:10.1080/000155598442809

    authors: Offidani A,Cellini A,Valeri G,Giovagnoni A

    更新日期:1998-11-01 00:00:00

  • Morphologic features and clinical significance of skin involvement in patients with AIDS-related cryptococcosis.

    abstract::Eight out of 30 consecutive patients with AIDS and cryptococcal meningoencephalitis (26,7%) presented cutaneous involvement, in the form of papulo-nodular lesions in 3 patients, molluscum contagiosum-like lesions in 3 patients, and pustular-ulcerative lesions in 2 patients. Skin localization represented an untoward pr...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555767274

    authors: Manfredi R,Mazzoni A,Nanetti A,Mastroianni A,Coronado O,Chiodo F

    更新日期:1996-01-01 00:00:00

  • A double-blind treatment study of bacterial vaginosis with normal vaginal lactobacilli after an open treatment with vaginal clindamycin ovules.

    abstract::The expected 4-week cure rate after conventional treatment of bacterial vaginosis are only 65-70%. In an attempt to improve the cure rate by adding probiotic lactobacilli we performed a double-blind placebo-controlled study of adjuvant lactobacilli treatment after an open treatment with vaginal clindamycin ovules. Wom...

    journal_title:Acta dermato-venereologica

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1080/00015550410022249

    authors: Eriksson K,Carlsson B,Forsum U,Larsson PG

    更新日期:2005-01-01 00:00:00

  • The constituents of keratohyalin granules of newborn rat epidermis under an electron microscopy.

    abstract::Three-day-old rat skins were treated either by the freezing--thawing method or by the tetraphenylboron technique. After the former procedure, keratohyalin granules were solubilized, leaving empty spaces with an electron-dense or less dense rim. Particles roughly 200 A in diameter, which were either electron-dense or l...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Tezuka T,Hirai R

    更新日期:1978-01-01 00:00:00

  • Transfer factor in mycosis fungoides: a case report on a patient "cured".

    abstract::A report is given of the successful treatment with transfer factor as an additional therapeutic agent of a patient in the tumour stage of mycosis fungoides who had not responded to conventional treatment with nitrogen mustard, methotrexate, or grenz rays alone. Besides twelve injections of transfer factor, the patient...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Zachariae H,Grunnet E,Thestrup-Pedersen K

    更新日期:1979-01-01 00:00:00

  • Cutaneous Manifestations of Granulomatosis with Polyangiitis: A Case Series Study.

    abstract::The aim of this study was to determine the prevalence and type of cutaneous manifestations which occur in patients with granulomatosis with polyangiitis and to explore the potential association between cutaneous and systemic involvement in these patients. A retrospective case series study was designed, including all g...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-3506

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    更新日期:2020-05-28 00:00:00

  • The influence of interferon-gamma and interleukin-4 on IgE production in B lymphocytes of patients with atopic dermatitis. A possible criterion for selection of patients for interferon therapy.

    abstract::The regulation of IgE production in B lymphocytes of patients with atopic dermatitis by interleukin-4 (IL-4) and interferon-gamma (IFN-gamma) was studied. IL-4 stimulated IgE production in vitro in B-cells of healthy donors and of children with atopic dermatitis, but had only a marginal effect on the high basal level ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Gruner S,Liebenthal C,Heusser C,Brinkmann V,Zwirner A,Reinicke C,Harnack K,Sönnichsen N,Volk HD

    更新日期:1991-01-01 00:00:00

  • Recall bias in childhood atopic diseases among adults in the Odense Adolescence Cohort Study.

    abstract::Atopic dermatitis (AD) is a common disease in childhood and an important risk factor for the later development of other atopic diseases. Many publications on childhood AD use questionnaires based on information obtained in adulthood, which introduce the possibility of recall bias. In a prospective cohort study, recall...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-2128

    authors: Mortz CG,Andersen KE,Bindslev-Jensen C

    更新日期:2015-11-01 00:00:00

  • Remission of ordinary psoriasis following a short clearance course of cyclosporin.

    abstract::We set out to show that the assumption is incorrect that continuous treatment with cyclosporin is necessary in psoriasis, as this tenet forms a basis for current recommended treatment regimens. Sixty patients with mild to moderate plaque psoriasis were allocated at random to treatment with oral cyclosporin 5 mg/kg/day...

    journal_title:Acta dermato-venereologica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.2340/00015555756569

    authors: Levell NJ,Shuster S,Munro CS,Friedmann PS

    更新日期:1995-01-01 00:00:00

  • Comparison of dithranol and butantrone in short contact therapy of psoriasis.

    abstract::Thirty psoriatic out-patients were treated as a right-left comparison with dithranol (0.1, 0.5, 1, 2%) and butantrone (0.66, 1.3, 2.7, 3.9%) short contact therapy, both in white petrolatum. Fifteen of the treated patients cleared well and no obvious differences between the treated sides were clinically observed. Six p...

    journal_title:Acta dermato-venereologica

    pub_type: 临床试验,杂志文章

    doi:

    authors: Göransson A

    更新日期:1987-01-01 00:00:00

  • Unusual structures in the epidermal Langerhans' cells of normal human skin.

    abstract::Two unusual structures were found in the epidermal Langerhans' cells of normal human adult skin: (1) an intramitochondrial crystalline lattice structure composed of numerous electron-dense, fine particles approximately 90 A in diameter, with a lucent spacing of nearly 90 A; (2) bundles of unusual cytoplasmic tubular s...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Morohashi M,Hashimoto K

    更新日期:1981-01-01 00:00:00

  • Increased Risk of Pemphigus among Patients with Psoriasis: A Large-scale Cohort Study.

    abstract::Although pemphigus has recently been linked to psoriasis, the risk of emergence of pemphigus during the course of psoriasis is yet to be delineated. The aim of this study was to evaluate the risk of developing pemphigus during the course of psoriasis. A large-scale population-based longitudinal retrospective cohort st...

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  • The role of low resistance blood flow pathways in the pathogenesis and healing of venous leg ulcers.

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    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/000155599750011435

    authors: Malanin K,Kolari PJ,Havu VK

    更新日期:1999-03-01 00:00:00

  • The histological and immunohistochemical pattern of positive patch test reactions to gold sodium thiosulfate.

    abstract::Gold sodium thiosulfate, inserted in the patch test standard series, gives a surprisingly high yield of positive reactions, about 10% of tested eczema patients, but with a low degree of clinical relevance. A histopathological study on patch test reactions was carried out in patients selected because of a combined cont...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/0001555574417423

    authors: Möller H,Larsson A,Björkner B,Bruze M

    更新日期:1994-11-01 00:00:00

  • Clinical variations in bullous pemphigoid with respect to early symptoms.

    abstract::We report the clinical variations and the duration of prodromal symptoms in 20 patients with bullous pemphigoid. Nearly two-thirds of the patients had prodromal symptoms. THe duration of the prodromal eruptions was up to 6 weeks if papular and/or urticarial and up to 2 years if eczematous, before the blisters appeared...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Asbrink E,Hovmark A

    更新日期:1981-01-01 00:00:00

  • Drug phototoxicity in mice.

    abstract::A series of agents with alleged photosensitizing properties has been studied in mice by a quantitative in vivo method for acute drug phototoxicity. The method, originally developed for phenothiazine studies, was found suitable for several drug groups with varying mechanism of action, such as tetracyclines, protoporphy...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Ljunggren B,Möller H

    更新日期:1978-01-01 00:00:00

  • Correlation between quantitative in vivo and in vitro responses in nickel-allergic patients.

    abstract::Forty-three nickel-allergic patients (40 females and 3 males) participated in this study which was designed to elucidate the correlation between quantitative in vivo and in vitro responses. All were patch-tested with various concentrations of nickel-sulphate serial-diluted in water. The lowest concentration eliciting ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Al-Tawil NG,Berggren G,Emtestam L,Fransson J,Jernselius R,Marcusson JA

    更新日期:1985-01-01 00:00:00

  • Dendrocytoclasis in Henoch-Schönlein purpura.

    abstract::We studied by immunohistochemistry the fate of factor XIIIa-positive dermal dendrocytes in Henoch-Schönlein purpura. We have observed apoptosis affecting most of the perivascular dendrocytes. Such an aspect of dendrocytoclasis has never previously been reported in inflammatory disorders in the absence of vasculitis. ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Estrada JA,Goffin F,Cornil F,Pierard-Franchimont C,Pierard GE

    更新日期:1991-01-01 00:00:00

  • Contact allergy to the active ingredients of Kathon CG in the guinea pig.

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    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Bruze M,Fregert S,Gruvberger B,Persson K

    更新日期:1987-01-01 00:00:00

  • Pooling samples: the key to sensitive, specific and cost-effective genetic diagnosis of Chlamydia trachomatis in low-resource countries.

    abstract::The aims of this study were to compare the performance characteristics and cost-effectiveness of pooling endocervical samples for screening and diagnosis of Chlamydia trachomatis, and to investigate the prevalence of C. trachomatis infection in women in Leningrad Oblast, Russia. A total of 1500 endocervical samples we...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-0196

    authors: Shipitsyna E,Shalepo K,Savicheva A,Unemo M,Domeika M

    更新日期:2007-01-01 00:00:00

  • Langerhans' cells in patients with psoriasis: effect of treatment with PUVA, PUVA bath, etretinate and anthralin.

    abstract::Suction blisters were raised in lesions and normal appearing skin of patients with psoriasis. The blister roof which contains the epidermis separated at the dermal-epidermal junction was stained with ATPase, OKT-6 and anti-HLA-DR monoclonal antibodies. The technique permits the counting of the Langerhans' cells per mm...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Czernielewski J,Juhlin L,Shroot S,Brun P

    更新日期:1985-01-01 00:00:00

  • Expression of stratum corneum chymotryptic enzyme in human sebaceous follicles.

    abstract::Stratum corneum chymotryptic enzyme (SCCE) may be involved in desquamation, a process necessary for maintaining a normal anatomy at all sites where there is continuous turnover of cornified epithelia. Using immunohistochemistry and in situ hybridization, we have, in this work, analysed SCCE expression in the sebaceous...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/000155598443015

    authors: Ekholm E,Sondell B,Strandén P,Brattsand M,Egelrud T

    更新日期:1998-09-01 00:00:00

  • Skin reactions to primary irritants in men and women.

    abstract::The skin reactions to skin provocation tests with 11 primary irritants were compared in 21 pairs of men and women with hand eczema, matched for age, and in 21 pairs of non-eczematous subjects. With a few exceptions, no statistically significant differences were demonstrated in the intensities of the skin reactions bet...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:102340/0001555555191194

    authors: Björnberg A

    更新日期:1975-01-01 00:00:00

  • Immunohistochemical examination of P-cadherin in bullous and acantholytic skin diseases.

    abstract::Autoimmune blistering diseases (pemphigus vulgaris, pemphigus foliaceus, bullous pemphigoid, dermatitis herpetiformis) and certain genodermatoses with acantholysis (Darier-disease, Hailey-Hailey disease) have different aetiological factors, but all result in bulla formation and/or in acantholysis. Cadherins are Ca++-d...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/00015550310006842

    authors: Kovács A,Schmidt E,Bégány A,Hunyadi J,Szegedi A

    更新日期:2004-01-01 00:00:00

  • Modulation of CD3-dependent lymphocyte proliferation by extracellular matrix proteins in atopic dermatitis.

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    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/0001555575353356

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    更新日期:1995-09-01 00:00:00

  • Hypersensitivity reactions to dapsone: a systematic review.

    abstract::Dapsone is widely used in the treatment of leprosy and several chronic inflammatory dermatological conditions. Hypersensitivity reactions to dapsone are potentially fatal adverse drug reactions with unknown prevalence and risk factors. We performed a systematic review covering all reported cases of hypersensitivity re...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章,评审

    doi:10.2340/00015555-1268

    authors: Lorenz M,Wozel G,Schmitt J

    更新日期:2012-03-01 00:00:00

  • Histamine and cutaneous nociception: histamine-induced responses in patients with atopic eczema, psoriasis and urticaria.

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    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/000155598433458

    authors: Heyer G,Koppert W,Martus P,Handwerker HO

    更新日期:1998-03-01 00:00:00

  • Effects of Extracellular Calcium and 1,25 dihydroxyvitamin D3 on Sebaceous Gland Cells In vitro and In vivo.

    abstract::Calcium and 1,25 dihydroxyvitamin D3 (1,25(OH)2D3) are promoters of epithelial cell functions; however their effects on sebaceous glands are unknown. In this study, morphology, ultrastructure, cell numbers, lipid synthesis and apoptosis of SZ95 sebocytes were assessed in vitro under different concentrations of extrace...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-2525

    authors: Zouboulis CC,Seltmann H,Abdel-Naser MB,Hossini AM,Menon GK,Kubba R

    更新日期:2017-03-10 00:00:00

  • Leukoplakia of the prepuce with epidermolytic hyperkeratosis: a case report.

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    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Kolde G,Vakilzadeh F

    更新日期:1983-01-01 00:00:00