Blood glutathione-peroxidase levels in skin diseases: effect of selenium and vitamin E treatment.

Abstract:

:Blood glutathione-peroxidase (GSH-Px) was determined in 61 healthy subjects and 506 patients with various skin disorders. Depressed levels were observed in patients with psoriasis, eczema, atopic dermatitis, vasculitis, mycosis fungoides and dermatitis herpetiformis. Low values of GSH-Px were also found in some patients with pemphigoid, acne conglobata, polymyositis, rheumatoid arthritis, scleroderma and systemic lupus erythematodes. Vegetarian diet, malnutrition and alcohol abuse could possibly account for the low values in some patients. Fifty patients with low GSH-Px levels were treated with tablets containing 0.2 mg selenium as Na2SeO3 and 10 mg tocopheryl succinate. The GSH-Px levels increased slowly within 6-8 weeks of treatment. The clinical effect was encouraging and calls for controlled studies.

journal_name

Acta Derm Venereol

authors

Juhlin L,Edqvist LE,Ekman LG,Ljunghall K,Olsson M

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

211-4

issue

3

eissn

0001-5555

issn

1651-2057

journal_volume

62

pub_type

杂志文章
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    doi:102340/0001555572610

    authors: Troilius A,Wårdell K,Bornmyr S,Nilsson GE,Ljunggren B

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  • In vivo and in vitro immune responses to trichophytin in dermatophytosis.

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    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Kaaman T,Petrini B,Wasserman J

    更新日期:1979-01-01 00:00:00

  • Nail--patella syndrome associated with renal failure requiring transplantation.

    abstract::The nail--patella syndrome is a rare, inheritable disease of the connective tissue in which multiple osseous abnormalities are associated with dysplasia of the nails. Renal dysfunction is found in 25--42% of cases and varies from asymptomatic proteinuria to renal failure. This paper describes a patient with nail--pate...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Verdich J

    更新日期:1980-01-01 00:00:00

  • Potentializing effect of ketoconazole on cyclosporin A-induced inhibition of keratinocyte DNA synthesis.

    abstract::Keratinocyte growth in vitro and DNA synthesis by epidermal cells in vivo are inhibited by therapeutic doses of cyclosporin A (CsA). This effect may be potentialized by topical treatment with ketoconazole, since this drug has been shown to inhibit CsA metabolism. Normal human skin grafts on nude mice receiving intrape...

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    pub_type: 杂志文章

    doi:10.2340/0001555574257259

    authors: Amsellem C,Haftek M,Thivolet J,De Doncker P,Schmitt D

    更新日期:1994-07-01 00:00:00

  • Bullous pyoderma gangrenosum in association with myeloid leukaemia.

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    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Cramers M

    更新日期:1976-01-01 00:00:00

  • Lower-limb Ulcers in Systemic Sclerosis: A Multicentre Retrospective Case-control Study.

    abstract::Lower-limb ulcers in systemic sclerosis patients are rarely reported. The aim of this study was to describe the main causes and outcomes of lower-limb ulcers in systemic sclerosis patients and to assess factors associated with ischaemic causes (arterial disease and/or microvascular impairment). A retrospective, multic...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章,多中心研究

    doi:10.2340/00015555-2939

    authors: Bohelay G,Blaise S,Levy P,Claeys A,Baudot N,Cuny JF,Maillard H,Granel-Brocard F,Boyé T,Lok C,Bénéton N,Francès C,Senet P

    更新日期:2018-07-11 00:00:00

  • Phylogenetic studies with pemphigus and pemphigoid antibodies.

    abstract::Indirect immunofluorescence (IF) studies were performed on skin from a variety of vertebrate specimens and IgG fractions from pemphigoid and pemphigus sera. Pemphigoid antigen was present in fish, amphibian, reptilian, avian and mammalian skin, whereas pemphigus antigen was observed in avian and mammalian skin only. ...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Diaz LA,Weiss HJ,Calvanico NJ

    更新日期:1978-01-01 00:00:00

  • Diagnosis of pigmented skin tumours in a dermatological setting: different aspects of the number needed to excise as a measure of efficiency.

    abstract::The increasing incidence of melanoma prompts a need for efficient management of this patient group. In this study, we use the number needed to excise (NNE), as a measurement of the efficiency of diagnosing melanoma. From January 2009 to December 2012, postoperative records from all patients were prospectively register...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-1831

    authors: Ahnlide I,Nielsen K,Bjellerup M

    更新日期:2014-11-01 00:00:00

  • Anthralin stick (Anthraderm) in the treatment of mosaic warts.

    abstract::Thirty patients having mosaic warts of the soles for 2 years (range 3 months-6 years) were treated daily with a wax-based anthralin stick supplemented by weekly paring. Six patients dropped out, because they failed to appear for follow-up. Of the remaining patients 17/24 cleared, whereas the warts persisted in 7/24. A...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Hjorth N,Madsen K,Nørgaard M

    更新日期:1986-01-01 00:00:00

  • Contact allergy to gold and gold therapy in patients with rheumatoid arthritis.

    abstract::Patients with rheumatoid arthritis were investigated for contact allergy to gold in connection with treatment with gold preparations. There were 57 patients with rheumatoid arthritis previously treated with gold, with or without cutaneous side-effects, as well as 20 patients intended for such treatment; all were expos...

    journal_title:Acta dermato-venereologica

    pub_type: 临床试验,杂志文章

    doi:10.2340/0001555577370373

    authors: Möller H,Svensson A,Björkner B,Bruze M,Lindroth Y,Manthorpe R,Theander J

    更新日期:1997-09-01 00:00:00

  • A two-step schedule for the treatment of actinomycotic mycetomas.

    abstract::Actinomycotic mycetomas usually respond slowly to treatment with antibiotics. In an attempt to hasten clinical resolution, we used a 2-step regimen consisting of an intensive phase of therapy with penicillin, gentamycin and co-trimoxazole for 5-7 weeks, followed by maintenance therapy with amoxicillin and co-trimoxazo...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.1080/000155500459367

    authors: Ramam M,Garg T,D'Souza P,Verma KK,Khaitan BK,Singh MK,Banerjee U

    更新日期:2000-09-01 00:00:00

  • The hair root pattern after calcipotriol treatment for scalp psoriasis.

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    journal_title:Acta dermato-venereologica

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.2340/0001555575388390

    authors: Kuijpers AL,van Baar HM,van Gasselt MW,van de Kerkhof PC

    更新日期:1995-09-01 00:00:00

  • Ultrastructure of murine dermis following topical application of the vitamin D3 analogue KH-1060.

    abstract::The aim of this study, was to observe the effects of KH-1060, a new vitamin D3 analogue, on the dermis of hairless mice by electron microscopy. KH-1060 (0.2 micrograms/ml in isopropanol) or KH-1060 following betamethasone 17-valerate (2 mg/ml in isopropanol) was applied topically to the backs of hairless mice for 4 we...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/0001555577198202

    authors: Kobayasi T

    更新日期:1997-05-01 00:00:00

  • Atopic dermatitis may be a genetically determined dysmaturation of ectodermal tissue, resulting in disturbed T-lymphocyte maturation. A hypothesis.

    abstract::Although atopic dermatitis is a skin disorder, it includes immune deviations such as T-cell accumulation and activation in the skin, resulting in chronic, relapsing eczema. The T-lymphocyte activation in the skin is not accompanied by specific allergies in up to two thirds of the patients. It has been shown that T-cel...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/0001555577020021

    authors: Thestrup-Pedersen K,Ellingsen AR,Olesen AB,Lund M,Kaltoft K

    更新日期:1997-01-01 00:00:00

  • Itch in Psoriasis: A New Look at Well-known Subject.

    abstract::Psoriasis is a chronic inflammatory dermatosis, frequently presenting with chronic itch. This study investigated the prevalence and detailed clinical characteristics of chronic itch in 143 psoriatic patients, with regard to different age groups, comorbidities and pharmacotherapy. Chronic itch was reported by 72% of su...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-3147

    authors: Reszke R,Białynicki-Birula R,Szepietowski JC

    更新日期:2019-04-01 00:00:00

  • Efficacy and skeletal side effects of two years' acitretin treatment.

    abstract::In this prospective study, 51 patients suffering from psoriasis and ichthyosis were treated with acitretin for 2 years. The average dose was 0.5 mg/kg/day. We have evaluated the efficacy and side effects, focusing on skeletal side effects. X-ray examinations were done before treatment and after 1 and 2 years. Forty-fi...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:102340/0001555572445448

    authors: Mørk NJ,Kolbenstvedt A,Austad J

    更新日期:1992-11-01 00:00:00

  • Identical glycine substitution mutations in type VII collagen may underlie both dominant and recessive forms of dystrophic epidermolysis bullosa.

    abstract::Autosomal dominant and recessive forms of dystrophic epidermolysis bullosa (DEB) result from mutations in the type VII collagen gene (COL7A1). Although paradigms have emerged for genotype/phenotype correlation in DEB, some pathogenic mutations in COL7A1, notably glycine substitutions within the type VII collagen tripl...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-1053

    authors: Almaani N,Liu L,Dopping-Hepenstal PJ,Lai-Cheong JE,Wong A,Nanda A,Moss C,Martinéz AE,Mellerio JE,McGrath JA

    更新日期:2011-05-01 00:00:00

  • Therapeutic effectiveness of various treatments for eosinophilic pustular folliculitis.

    abstract::Eosinophilic pustular folliculitis is a rare dermatosis. Recently, in addition to oral indomethacin, other treatments have been applied for eosinophilic pustular folliculitis. The aim of this study was to assess the effectiveness of various therapies encompassing conventional to newly applied drugs for eosinophilic pu...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/00015555-0578

    authors: Fukamachi S,Kabashima K,Sugita K,Kobayashi M,Tokura Y

    更新日期:2009-01-01 00:00:00

  • Contact allergy to the active ingredients of Kathon CG in the guinea pig.

    abstract::Preservative Kathon CG (K-CG) is a commercial preparation, consisting of the two active ingredients (a.i.), 2-methyl-4-isothiazolin-3-one (243-K-CG) and 5-chloro-2-methyl-4-isothiazolin-3-one (5243-K-CG) and also of other components. Both a.i. are known contact sensitizers in humans. In this study guinea pig maximizat...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Bruze M,Fregert S,Gruvberger B,Persson K

    更新日期:1987-01-01 00:00:00

  • Hair root studies in patients suffering from primary and secondary syphilis.

    abstract::The hair root status (trichogram) was studied in eleven patients with primary and eight with secondary syphilis. Variables studied in addition to the hair roots were absence or presence of hair root sheaths, deformities and hair roots with angulations exceeding 20 degrees. A decrease in the number of anagen hair roots...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: van der Willigen AH,Peereboom-Wynia JD,van der Hoek JC,Mulder PG,van Joost TH,Stolz E

    更新日期:1987-01-01 00:00:00

  • Atopic dermatitis, house dust mite allergy and month of birth.

    abstract::An analysis of the month of birth in 210 patients with atopic dermatitis and a positive prick test towards the house dust mite (Dermatophagoides pteronyssinus) showed a significantly higher prevalence of birth in the interval May to November when compared with the expected distribution (p less than 0.01). A subdivisio...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Beck HI,Hagdrup HK

    更新日期:1987-01-01 00:00:00

  • An experimental study evaluating the effect of minoxidil on the growth cycle of hair follicles.

    abstract::The possibility that topically-applied minoxidil might affect the growth cycle of hair follicles was studied in inbred Herston white mice and HRA/Skh1 hairless mice. In the normal follicular cycle, the anagen or growth phase can be followed by autoradiographic demonstration of [3H]thymidine uptake in proliferating mat...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Gobé GC,Strutton GM

    更新日期:1989-01-01 00:00:00

  • Adult human skin maintained in organ culture. II. The ultrastructure of the cellular compartment of connective tissue.

    abstract::Dermal cells maintained in cultured human skin explants for up to 10 weeks were studied by electron microscopy. Common findings in the cell organelles were: 1) altered nuclear shapes and numerous nuclear bodies; 2) reduced rough endoplasmic reticulum; 3) a prominent Golgi complex; and 4) an increasing number of free r...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:

    authors: Hentzer B,Kobayasi T

    更新日期:1980-01-01 00:00:00

  • Intralesional interferon alpha-2b therapy for Buschke-Loewenstein tumour.

    abstract::A patient with a Buschke-Loewenstein tumour associated with human papillomavirus type 6/11 is reported. He was intralesionally treated with human recombinant alpha-2b interferon (9 x 10(6) IU/day) three times weekly. The tumour completely disappeared within 5 months of continuous treatment which was well tolerated. Si...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章

    doi:10.2340/0001555574457459

    authors: Tsambaos D,Monastirli A,Kapranos N,Georgiou S,Pasmatzi E,Berger H

    更新日期:1994-11-01 00:00:00

  • Congenital reticular ichthyosiform erythroderma--ichthyosis variegata: a case report and review of the literature.

    abstract::We present a 32-year-old white patient with congenital reticular ichthyosiform erythroderma, also known as ichthyosis variegata. The patient had typical clinical features with areas of normal appearing skin surrounded by erythematous hyperkeratotic patches. The smaller "confetti-like" patches were mostly present on th...

    journal_title:Acta dermato-venereologica

    pub_type: 杂志文章,评审

    doi:10.1080/00015550310002684

    authors: Krunic AL,Palcesky D,Busbey S,Medenica M

    更新日期:2003-01-01 00:00:00

  • Red lunulae in severe alopecia areata.

    abstract::The development of red nail lunulae has been extremely rarely described in alopecia areata. We observed 2 patients, a 30-year-old woman and a 61-year-old man, both suffering from severe alopecia areata, and having red lunulae. The colour changes, which developed a few weeks after the acute onset of hair loss, disappea...

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    pub_type: 杂志文章

    doi:102340/0001555572203205

    authors: Bergner T,Donhauser G,Ruzicka T

    更新日期:1992-01-01 00:00:00

  • Kinetics of phototoxicity in trioxysalen bath psoralen plus ultraviolet A photochemotherapy.

    abstract::A trioxysalen bath is a safe alternative to systemic 8-methoxypsoralen in long-term psoralen plus ultraviolet A (PUVA) treatment. The kinetics of its main side-effect, the strong phototoxicity, has not been thoroughly studied. This study determined the degree and persistence of phototoxicity after a single 10 min bath...

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    pub_type: 杂志文章

    doi:10.1080/000155501750376230

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  • Psoriasis as a Predictor of Cardiometabolic Comorbidity in Women: A Study Based on the Danish National Birth Cohort.

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  • The effect of treatment on quality of life in psoriasis patients.

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  • Contact thermography for assessment of skin damage due to experimental irritants.

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    doi:

    authors: Agner T,Serup J

    更新日期:1988-01-01 00:00:00