Urinary glycosaminoglycans excretion in Graves' disease.

Abstract:

:Urinary excretion of glycosaminoglycans was measured in 10 patients with pretibial myxoedema, 7 of whom also had thyroid-associated ophthalmopathy, and in 3 additional patients with ophthalmopathy but no skin changes. Total uronic acid excretion was raised above control levels in only 2 patients, who had both eye and skin disease of recent onset. In these patients excretion was initially three times the control level but declined sharply in subsequent months. This decline was in the absence of effective treatment or spontaneous improvement and would appear to reflect the natural history of the disease. These data show that although glycosaminoglycans excretion may be disturbed in Graves' disease, it provides an unreliable reflection of clinical status and of the effectiveness of treatment.

journal_name

Acta Derm Venereol

authors

Priestley GC,Aldridge RD,Hurel S

doi

10.2340/0001555576368370

subject

Has Abstract

pub_date

1996-09-01 00:00:00

pages

368-70

issue

5

eissn

0001-5555

issn

1651-2057

journal_volume

76

pub_type

杂志文章
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  • Chlamydia trachomatis urethritis in men attending a venereal disease clinic: a culture and therapeutic study.

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