Paired Basic Amino Acid-cleaving Enzyme 4 (PCSK6): An Emerging New Target Molecule in Human Melanoma.

abstract：:Halo naevi are considered benign. They occur in children and adolescents. Eruptive multiple halo naevi are infrequently seen in adults. The first patient in this case series had previously had melanoma. Positron emission tomography-computed tomography (PET-CT) showed a papillary thyroid carcinoma. Subsequent adult pat...

journal_title：Acta dermato-venereologica

authors： Lorentzen HF

更新日期：2020-08-17 00:00:00

abstract：:Oxidation of 5-S-cysteinyldopa by mushroom tyrosinase was studied by measuring 5-S-cysteinyldopa consumption with HPLC. 5-S-cysteinyldopa was found to be a substrate for tyrosinase, but our results suggests that a self-catalysed oxidation induced by enzymatically formed 5-S-cysteinyl dopaquinone also takes place. Dopa...

journal_title：Acta dermato-venereologica

authors： Hansson C,Rorsman H,Rosengren E

更新日期：1980-01-01 00:00:00

abstract：:A case of Sweet's syndrome treated with potassium iodide is hereby described. The patient responded well a few days after the initiation of therapy, but the evolution was complicated with a severe clinical deterioration two weeks later. Systemic vasculitis was diagnosed on the basis of significant impairment of renal ...

journal_title：Acta dermato-venereologica

authors： Eeckhout E,Willemsen M,Deconinck A,Somers G

更新日期：1987-01-01 00:00:00

abstract：:We studied by immunohistochemistry the fate of factor XIIIa-positive dermal dendrocytes in Henoch-Schönlein purpura. We have observed apoptosis affecting most of the perivascular dendrocytes. Such an aspect of dendrocytoclasis has never previously been reported in inflammatory disorders in the absence of vasculitis. ...

journal_title：Acta dermato-venereologica

authors： Estrada JA,Goffin F,Cornil F,Pierard-Franchimont C,Pierard GE

更新日期：1991-01-01 00:00:00

abstract：:Patients with atopic dermatitis were found to have an about 7-fold increased spontaneous proliferative response of peripheral blood lymphocytes and an about 4-fold elevation of CD3-dependent lymphocyte transformation as compared to normal controls. The CD3-dependent lymphocyte response in patients with severe atopic d...

journal_title：Acta dermato-venereologica

authors： Glinski W,Stepien-Sopniewska B,Korczak-Kowalska G,Glinska-Ferenz M,Gorski A

更新日期：1995-09-01 00:00:00

abstract：:Human leukocytes and fibroblasts were cultured in medium containing 3H-8-methoxypsoralen (10(-6) M and 3.3 X 10(-6) M). At different stages during the culturing period the cells were exposed to ultraviolet light (1, 2, and 10 J/cm2). After the culture period the slides for chromosome analysis and smears of the cells w...

journal_title：Acta dermato-venereologica

authors： Wulf HC,Niebuhr E

更新日期：1980-01-01 00:00:00

abstract：:Psoriasis has major physical, psychological, and social impacts: its management should not be restricted by individual financial considerations in Western countries as these have well-structured health systems and social/insurance coverage. We investigated if the socioeconomic characteristics of patients were associat...

journal_title：Acta dermato-venereologica

authors： Mahé E,Beauchet A,Reguiai Z,Maccari F,Ruer-Mulard M,Chaby G,Le Guyadec T,Estève E,Goujon-Henry C,Parier J,Barthelemy H,Bégon E,Steiner HG,Bénéton N,Boyé T,Mery-Bossard L,Schmutz JL,Bravard P,Michèle-Léa Sigal and the

更新日期：2017-05-08 00:00:00

abstract：:Alexithymia, defined as difficulty in describing or recognizing emotions, has been shown to be connected with psoriasis, but its relationship with self-management of psoriasis has not been explored. The aim of this study was to assess the frequency of alexithymia and its relationship with self-management and illness p...

journal_title：Acta dermato-venereologica

authors： Larsen MH,Krogstad AL,Wahl AK

更新日期：2017-08-31 00:00:00

abstract：:Pain and discomfort are common and often severe skin symptoms in patients with psoriasis. However, no studies have investigated skin pain and discomfort over time, or factors that explain changes in these symptoms. The aims of the present study were to describe the changes in skin pain, skin discomfort and Psoriasis A...

journal_title：Acta dermato-venereologica

authors： Ljosaa TM,Stubhaug A,Mork C,Moum T,Wahl AK

更新日期：2013-05-01 00:00:00

abstract：:Atopic dermatitis (AD) has a big impact on quality of life. The usefulness of health-related quality of life questionnaires for children with AD in general practice, and the relationship of quality of life to disease severity, as assessed by parents and by investigators, however, is not known. This study used the Infa...

journal_title：Acta dermato-venereologica

authors： van Valburg RW,Willemsen MG,Dirven-Meijer PC,Oranje AP,van der Wouden JC,Moed H

更新日期：2011-03-01 00:00:00

abstract：:The urine of an albino woman contained small quantities of 5-S-cysteinyldopa; 6-hydroxy-5-methoxyindole-2-carboxylic acid, a melanin precursor metabolite, was lacking. The 5-S-cysteinyldopa excretion observed may reflect non-specific oxidation of dopa. Two other albino patients showed normal values for the excretion o...

journal_title：Acta dermato-venereologica

authors： Carstam R,Hansson C,Krook G,Rorsman H,Rosengren E,Wirestrand LE

更新日期：1985-01-01 00:00:00

abstract：:Peripheral blood lymphocytes from 45 patients with a positive patch test to cobalt chloride (CoCl2) and 37 controls were stimulated with various concentrations of CoCl2 and/or cobalt sulphate (CoSO4) or cobalt nitrate (Co(NO3)2) or cobalt acetate [CH3COO)2Co) for various days in culture. Lymphocytes from 35 of these p...

journal_title：Acta dermato-venereologica

authors： Al-Tawil NG,Marcusson JA,Möller E

更新日期：1984-01-01 00:00:00

abstract：:The purpose of this investigation was to study the intestinal absorption of L-tryptophan and to assess the absorptive function of the intestine in scleroderma. The oral L-tryptophan loading test was performed in 31 cases of systemic scleroderma (progressive systemic sclerosis, PSS) and 3 cases of localized scleroderma...

journal_title：Acta dermato-venereologica

authors： Stachow A,Jablońska S,Skiendzielewska A

更新日期：1976-01-01 00:00:00

abstract：:Intraepidermal collections of neutrophils and lymphocytes are unique features of the inflammatory reaction of psoriasis. Migration of leukocytes from dermis to the epidermis suggests a role for chemotactic agent(s). In recent years, increased levels of chemokines such as IL-8 , GRO-a and MCP-1 have been reported in th...

journal_title：Acta dermato-venereologica

authors： Raychaudhuri SP,Jiang WY,Farber EM,Schall TJ,Ruff MR,Pert CB

更新日期：1999-01-01 00:00:00

abstract：:Skin microdialysis is an established method for in vivo sample collection from the extracellular fluid space. This method has been extensively used in studies of inflammatory reactions in the skin of animals and humans. Skin microdialysis consists of the implantation of semi-permeable probes into the upper dermis, per...

journal_title：Acta dermato-venereologica

authors： Hersini KJ,Melgaard L,Gazerani P,Petersen LJ

更新日期：2014-09-01 00:00:00

abstract：:Basal cell carcinomas are the most frequent skin cancers in the fair-skinned adult population over 50 years of age. Their incidence is increasing throughout the world. Ultraviolet (UV) exposure is the major carcinogenic factor. Some genodermatosis can predispose to formation of basal cell carcinomas at an earlier age....

journal_title：Acta dermato-venereologica

authors： Basset-Seguin N,Herms F

更新日期：2020-06-03 00:00:00

abstract：:The effect of a protective cream was tested in a new tandem repeated irritation test with tandem application of 0.5% sodium lauryl sulphate (SLS) and undiluted toluene. The irritants were applied twice daily for 30 min to the ventral forearms of 20 volunteers. Irritant cutaneous reactions were quantified by a visual s...

journal_title：Acta dermato-venereologica

authors： Wigger-Alberti W,Spoo J,Schliemann-Willers S,Klotz A,Elsner P

更新日期：2002-01-01 00:00:00

abstract：:Monocytes form a significant component of the inflammatory reaction taking place in the skin of atopic dermatitis and psoriasis. Chemokines are pivotal in mediating the attraction of leucocytes to sites of inflammation. The CC-chemokine, monocyte chemotactic protein 1 (MCP-1/CCL2), is expressed by keratinocytes in bot...

journal_title：Acta dermato-venereologica

authors： Vestergaard C,Just H,Baumgartner Nielsen J,Thestrup-Pedersen K,Deleuran M

更新日期：2004-01-01 00:00:00

abstract：:A female presenting multiple osteoma cutis lesions without underlying endocrinological disturbance was studied. Histologically, lesions revealed true bone formation with multiple osteoblastic cells. This was confirmed by demonstrating high alkaline phosphatase activity and osteonectin expression in osteoma cutis lesio...

journal_title：Acta dermato-venereologica

authors： Oikarinen A,Tuomi ML,Kallionen M,Sandberg M,Väänänen K

更新日期：1992-01-01 00:00:00

abstract：:A 31-year-old woman developed typical clinical and laboratory signs of PCT at the end of her second pregnancy coincident with the summer season. She had elevated liver function values without history of alcoholism, hepatitis or chemical liver damage. She had taken oral contraceptive only before her first pregnancy whi...

journal_title：Acta dermato-venereologica

authors： Rajka G

更新日期：1984-01-01 00:00:00

abstract：:The aim of this study is to assess the associations between chronic spontaneous urticaria (CSU), Helicobacter pylori infection and small intestinal bacterial overgrowth. Forty- eight patients with CSU were studied by scoring the urticaria activity and assesing the quality of life. Patients with H. pylori infection (n=...

journal_title：Acta dermato-venereologica

authors： Campanati A,Gesuita R,Giannoni M,Piraccini F,Sandroni L,Martina E,Conocchiari L,Bendia E,Di Sario A,Offidani A

更新日期：2013-03-27 00:00:00

abstract：:Itch is known to be associated with psychological factors in adults, but has not been explored among adolescents. A cross-sectional, questionnaire-based population study involving adolescents born mostly in 1986 was carried out in 2004. A total of 4744 individuals were invited and the participation rate was 80%. The H...

journal_title：Acta dermato-venereologica

authors： Halvorsen JA,Dalgard F,Thoresen M,Thoresen M,Bjertness E,Lien L

更新日期：2009-01-01 00:00:00

abstract：:Anti-interleukin-17 agents have recently been developed for the treatment of psoriasis. This study evaluated the tolerance and effectiveness of anti-interleukin-17 agents for psoriasis in elderly patients in daily practice. A multicentre, retrospective study was performed, involving psoriatic patients aged ≥65 years w...

journal_title：Acta dermato-venereologica

authors： Phan C,Beneton N,Delaunay J,Reguiai Z,Boulard C,Fougerousse AC,Cinotti E,Romanelli M,Mery-Bossard L,Thomas-Beaulieu D,Parier J,Maccari F,Perrot JL,Ruer-Mulard M,Bastien M,Begon E,Samimi M,Jacobzone C,Quiles-Tsimaratos

更新日期：2020-11-04 00:00:00

abstract：:Stratum corneum chymotryptic enzyme (SCCE) may be involved in desquamation, a process necessary for maintaining a normal anatomy at all sites where there is continuous turnover of cornified epithelia. Using immunohistochemistry and in situ hybridization, we have, in this work, analysed SCCE expression in the sebaceous...

journal_title：Acta dermato-venereologica

authors： Ekholm E,Sondell B,Strandén P,Brattsand M,Egelrud T

更新日期：1998-09-01 00:00:00

abstract：:Biological drugs are expensive, but can reduce symptoms and increase quality of life for patients with psoriasis. The aim of this study was to examine quality of life, disease severity and treatment satisfaction in Danish, Finnish and Swedish patients with psoriasis. Based on 12 months' data from patient surveys and c...

journal_title：Acta dermato-venereologica

authors： Ragnarson Tennvall G,Hjortsberg C,Bjarnason A,Gniadecki R,Heikkilä H,Jemec GB,Kragballe K,Miller IM,Svensson Å

更新日期：2013-07-06 00:00:00

abstract：:Cutaneous leishmaniasis poses a therapeutic challenge in the paediatric population. The aim of this study was to assess the efficacy and safety of miltefosine treatment for Old World cutaneous leishmaniasis in paediatric patients. A multicentre retrospective review of 10 children (≤ 18 years of age) with cutaneous lei...

journal_title：Acta dermato-venereologica

authors： Ollech A,Solomon M,Horev A,Reiss-Huss S,Ben-Amitai D,Zvulunov A,Friedland R,Atar-Snir V,Molho-Pessach V,Barzilai A,Greenberger S

更新日期：2020-10-19 00:00:00

abstract：:A noninvasive Finn Chamber sampling method and HPLC analysis were used to determine epidermal urocanic acid (UCA) concentrations of psoriasis patients during 4 weeks of heliotherapy on the Spanish Canary Islands and a follow-up period of 8 weeks. During heliotherapy the epidermal cis-UCA concentration increased from a...

journal_title：Acta dermato-venereologica

authors： Snellman E,Koulu L,Pasanen P,Lammintausta K,Neuvonen K,Ayräs P,Jansén CT

更新日期：1992-01-01 00:00:00

abstract：:Familial progressive hyperpigmentation is rarely described in the literature. We report on five patients from three different families presenting with a peculiar progressive pigmentary disorder. The patients show a progressive diffuse, partly blotchy, hyperpigmentation, intermixed with scattered small hypopigmented ma...

journal_title：Acta dermato-venereologica

authors： Zanardo L,Stolz W,Schmitz G,Kaminski W,Vikkula M,Landthaler M,Vogt T

更新日期：2004-01-01 00:00:00

abstract：:is missing (Quiz). ...

journal_title：Acta dermato-venereologica

authors： Kaisho J,Egawa G,Kaku Y,Kabashima K

更新日期：2020-08-17 00:00:00

abstract：:A 45-year-old woman with solar urticaria is described. She was found to have: (a) increase of skin mast cells; (b) a good therapeutic response to hydroxyzine hydrochloride; (c) frequent peptic ulcers of the stomach; (d) antinuclear IgM antibodies in a titre of 1 : 1 000; (e) cold urticaria and dermographism; (f) anamn...

journal_title：Acta dermato-venereologica

authors： Rantanen T,Suhonen R

更新日期：1980-01-01 00:00:00