Abstract:
:Recently, atomic models of the mammalian, fungal and the bacterial fatty acid synthases type I (FAS I) were reported. Now, a wealth of functional data, collected during the last decades, can be embedded into structural frames. But there is more, which remains to be done! Our current considerations are implicitly very much based on a static view onto these proteins. The next step is to include the dynamic processes, which are essential for the function of FAS I. In this perspective, aspects of the current knowledge are reviewed and presented as the basis for the scientific challenges in a new epoch of FAS research.
journal_name
Curr Opin Struct Bioljournal_title
Current opinion in structural biologyauthors
Grininger Mdoi
10.1016/j.sbi.2013.12.004subject
Has Abstractpub_date
2014-04-01 00:00:00pages
49-56eissn
0959-440Xissn
1879-033Xpii
S0959-440X(13)00213-3journal_volume
25pub_type
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journal_title:Current opinion in structural biology
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journal_title:Current opinion in structural biology
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journal_title:Current opinion in structural biology
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journal_title:Current opinion in structural biology
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journal_title:Current opinion in structural biology
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journal_title:Current opinion in structural biology
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journal_title:Current opinion in structural biology
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journal_title:Current opinion in structural biology
pub_type: 杂志文章,评审
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journal_title:Current opinion in structural biology
pub_type: 杂志文章,评审
doi:10.1016/j.sbi.2007.01.003
更新日期:2007-02-01 00:00:00
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journal_title:Current opinion in structural biology
pub_type: 杂志文章,评审
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更新日期:2015-02-01 00:00:00
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journal_title:Current opinion in structural biology
pub_type: 杂志文章,评审
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更新日期:2000-10-01 00:00:00
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journal_title:Current opinion in structural biology
pub_type: 杂志文章,评审
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更新日期:2006-08-01 00:00:00
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journal_title:Current opinion in structural biology
pub_type: 杂志文章,评审
doi:10.1016/j.sbi.2014.01.010
更新日期:2014-02-01 00:00:00
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journal_title:Current opinion in structural biology
pub_type: 杂志文章,评审
doi:10.1016/s0959-440x(00)00154-8
更新日期:2000-12-01 00:00:00
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journal_title:Current opinion in structural biology
pub_type: 杂志文章,评审
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journal_title:Current opinion in structural biology
pub_type: 杂志文章,评审
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journal_title:Current opinion in structural biology
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journal_title:Current opinion in structural biology
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journal_title:Current opinion in structural biology
pub_type: 杂志文章,评审
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journal_title:Current opinion in structural biology
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journal_title:Current opinion in structural biology
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:Current opinion in structural biology
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pub_type: 杂志文章,评审
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journal_title:Current opinion in structural biology
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journal_title:Current opinion in structural biology
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abstract::Glycosylation is a common post-translational protein modification, in which glycans are built onto proteins through the sequential addition of monosaccharide units, in reactions catalysed by glycosyltransferases. Glycosylation influences the physicochemical and biological properties of proteins, with subsequent effect...
journal_title:Current opinion in structural biology
pub_type: 杂志文章,评审
doi:10.1016/j.sbi.2016.08.007
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