Abstract:
:Progress in structural biology has begun to reveal the precise architecture of integral membrane proteins. However, the manner in which these complex structures are achieved remains unclear. Recent developments are starting to shed light on the unfolding and folding of a small but growing number of membrane proteins. Mechanistic details derived from kinetic and thermodynamic experiments now enable comparison of the folding of different membrane proteins and their water-soluble cousins. This work also has important implications for other structural and functional studies of membrane proteins in vitro.
journal_name
Curr Opin Struct Bioljournal_title
Current opinion in structural biologyauthors
Booth PJ,Curnow Pdoi
10.1016/j.sbi.2006.06.004subject
Has Abstractpub_date
2006-08-01 00:00:00pages
480-8issue
4eissn
0959-440Xissn
1879-033Xpii
S0959-440X(06)00108-4journal_volume
16pub_type
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journal_title:Current opinion in structural biology
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journal_title:Current opinion in structural biology
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