Utility of magnetization prepared GRE MRI for the detection of focal liver lesions.

Abstract:

:We compared the efficacy of rapidly acquired magnetization prepared gradient-echo (MP-GRE) sequences with CT and standard MRI pulse sequences for the detection of focal liver lesions. Fourteen patients with 28 focal liver lesions were scanned. TI times of 300, 450, and 600 ms were used. MP-GRE lesion conspicuity was compared to corresponding CT, T1, T2, T2-post-superparamagnetic-iron-oxide (SPIO), and STIR images. It was found that the differences between MP-GRE and CT and MP-GRE and T1 MRI were not significant. However, overall anatomic detail was better with CT and T1 MRI than MP-GRE. Lesion conspicuity was significantly worse with the MP-GRE than with the T2, T2-post-SPIO, and STIR sequences (all p values = 0.00). Maximal liver signal nulling occurred at TI = 300 ms in 13 out of 14 patients. However, the T1 for optimal focal liver lesion conspicuity varied widely and could not be predicted before scanning. No new lesions were seen on the MP-GRE sequence that could not be seen on the CT or standard MRI sequences. As currently implemented, MP-GRE imaging offers no advantage in the detection of focal liver lesions over CT and standard MRI pulse sequences.

journal_name

Magn Reson Imaging

authors

Winter TC 3rd,Freeny PC,Nghiem HV,Thomas CR Jr

doi

10.1016/0730-725x(94)92198-9

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

733-42

issue

5

eissn

0730-725X

issn

1873-5894

pii

0730-725X(94)92198-9

journal_volume

12

pub_type

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