Rye products in the diabetic diet. Postprandial glucose and hormonal responses in non-insulin-dependent diabetic patients as compared to starch availability in vitro and experiments in rats.

Abstract:

:Rye flakes, rye bread and white wheat bread were given as suspensions to rats and in standardized breakfast meals to non-insulin-dependent diabetics. In both cases the postprandial glucose response was lower after rye bread than after wheat bread. A larger amount of starch remained in the stomach of the rats 15 min after ingesting rye bread compared to wheat bread, indicating that delayed gastric emptying may be one factor explaining the lower response after rye bread. Although the incremental postprandial glucose areas after rye flakes and wheat bread were similar, the rate of decrease of the glucose curve was slower after flaked rye. This would point to a prolonged absorption of some starch in the rye flakes, also indicated by higher late immunoreactive insulin (IRI) values after that product. In the rats the content of starch in the stomachs 15 min after feeding was higher after rye flakes compared to wheat bread. In vitro incubations with alpha-amylase showed lower availability of the starch in rye flakes than in the breads, indicating that several factors may contribute to the differential postprandial glucose response after the wheat and rye products. The levels of insulin, C-peptide, gastric inhibitory polypeptide (GIP), glucagon, somatostatin, triglyceride and glycerol were followed after the breakfast meals. No pronounced differences of these parameters were seen. However, wheat bread gave significantly higher glucagon and GIP responses than did rye flakes. In conclusion, the absorption pattern and metabolic response after rye bread seems preferable to that after wheat bread. The flaked rye on the other hand was not effective in reducing postprandial glycaemia despite a lower availability of starch in vitro.

authors

Hagander B,Björck I,Asp NG,Efendić S,Holm J,Nilsson-Ehle P,Lundquist I,Scherstén B

doi

10.1016/s0168-8227(87)80012-8

subject

Has Abstract

pub_date

1987-03-01 00:00:00

pages

85-96

issue

2

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(87)80012-8

journal_volume

3

pub_type

杂志文章
  • Development and validation of PRISM: a survey tool to identify diabetes self-management barriers.

    abstract:AIMS:Although most children with type 1 diabetes do not achieve optimal glycemic control, no systematic method exists to identify and address self-management barriers. This study develops and validates PRISM (Problem Recognition in Illness Self-Management), a survey-based tool for efficiently identifying self-managemen...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2014.01.015

    authors: Cox ED,Fritz KA,Hansen KW,Brown RL,Rajamanickam V,Wiles KE,Fate BH,Young HN,Moreno MA

    更新日期:2014-04-01 00:00:00

  • Increased levels of aldose reductase in peripheral mononuclear cells from type 2 diabetic patients with microangiopathy.

    abstract::Aldose reductase (AR) protein was measured in peripheral mononuclear cells (PMCs) from 55 patients with type 2 diabetes by a two-site ELISA using anti-human AR monoclonal antibody. AR levels did not correlate with age, duration of diabetes, and HbAlc. Furthermore, no significant differences were found in AR levels bet...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(99)00054-6

    authors: Hasegawa G,Obayashi H,Kitamura A,Hashimoto M,Shigeta H,Nakamura N,Kondo M,Nishimura CY

    更新日期:1999-08-01 00:00:00

  • Factors influencing the clinical outcome of continuous subcutaneous insulin infusion in routine practice.

    abstract::Possible factors that might influence the outcome of continuous subcutaneous insulin infusion (CSII) treatment were investigated in forty-nine, type 1, diabetic patients with median treatment of 3.25 years in routine diabetes care. In nine patients pump treatment was discontinued largely within the first 6 months. Pat...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(93)90145-u

    authors: Wredling R,Lins PE,Adamson U

    更新日期:1993-01-01 00:00:00

  • Impact of mitochondrial ROS production on diabetic vascular complications.

    abstract::Vascular complications are the leading cause of morbidity and mortality in patients with diabetes. Four main molecular mechanisms have been implicated in glucose-mediated vascular disease. There are: glucose-induced activation of protein kinase C (PKC) isoforms; increased formation of glucose-derived advanced glycatio...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2007.01.031

    authors: Nishikawa T,Kukidome D,Sonoda K,Fujisawa K,Matsuhisa T,Motoshima H,Matsumura T,Araki E

    更新日期:2007-09-01 00:00:00

  • Factor analysis of diabetic retinopathy in Chinese patients.

    abstract:OBJECTIVE:To investigate factors related to diabetic retinopathy (DR). METHOD:Clinical data of 603 Chinese diabetic patients were analyzed retrospectively. On the basis of its severity, DR was graded as non-diabetic retinopathy (NDR), non proliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2011.02.007

    authors: Zheng W

    更新日期:2011-05-01 00:00:00

  • Start improving the quality of care for people with type 2 diabetes through a general practice support program: a cluster randomized trial.

    abstract:AIMS:To evaluate the effectiveness of a two-arm quality improvement program (QIP) to support general practice with limited tradition in chronic care on type 2 diabetes patient outcomes. METHODS:During 18 months, we performed a cluster randomized trial with randomization of General Practices. The usual QIP (UQIP: 53 GP...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.diabres.2009.12.012

    authors: Goderis G,Borgermans L,Grol R,Van Den Broeke C,Boland B,Verbeke G,Carbonez A,Mathieu C,Heyrman J

    更新日期:2010-04-01 00:00:00

  • Impact of maternal height and gestational diabetes mellitus on offspring birthweight.

    abstract:AIMS:To evaluate the impact of gestational diabetes mellitus (GDM) and maternal height on offspring birthweight. METHODS:This is an observational cohort study, encompassing 4 111 Finnish primiparous women from Vantaa city, Finland, with singleton deliveries between 2009 and 2015. Data were obtained from the Finnish Me...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2019.01.004

    authors: Masalin S,Laine MK,Kautiainen H,Gissler M,Raina M,Pennanen P,Eriksson JG

    更新日期:2019-02-01 00:00:00

  • Association of serum apolipoprotein C III levels and apolipoprotein C III gene Sst I polymorphism with carotid intima-media thickness in Chinese type 2 diabetic patients.

    abstract::Apolipoprotein C III (apo C III) plays a central role in regulating plasma metabolism of triglyceride-rich lipoprotein (TRL). The G3238C allele (Sst I) in the 3'-untranslated region has been found to be associated with raised apo C III levels and hypertriglyceridemia (HTG). Some studies suggest that apo C III and the ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2004.02.020

    authors: Chen X,Tian H,Liu R

    更新日期:2004-10-01 00:00:00

  • Glucose and insulin responses to intravenous glucose challenge in relatives of Nigerian patients with non-insulin-dependent diabetes mellitus.

    abstract::We analysed blood insulin and glucose concentrations before and during frequently sampled intravenous glucose tolerance tests (FSIGT) in 2 groups of Nigerian subjects: (A) Control group (n = 18), without a positive family history of diabetes mellitus, and (B) Experimental group (n = 16), comprising age-, sex- and body...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(93)90075-g

    authors: Ezenwaka CE,Akanji AO,Osei K,Adejuwon CA,O'Dorisio TM,Cottrell DA,Akinlade KS

    更新日期:1993-06-01 00:00:00

  • Epidemiology of childhood diabetes in Osaka District, Japan, using the documents from the medical benefits system specific for childhood diabetes.

    abstract::For an epidemiological study of childhood diabetes, application forms for medical benefits filed in Osaka Prefecture were collected and analyzed. A total of 465 patients with childhood diabetes under 18 yr of age were identified during the period between 1978 and 1988; 371 (175 boys and 196 girls) of them were classif...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(92)90145-h

    authors: Sasaki A,Okamoto N

    更新日期:1992-12-01 00:00:00

  • Correlates of health care use among White and minority men and women with diabetes: An NHANES study.

    abstract:AIMS:The current study sought to identify patient-level factors related to health care use among White and minority men and women with diabetes. METHODS:A sample of 447 of non-pregnant individuals with diabetes, ages 18-64, was drawn from the 2015-2016 National Health and Nutrition Examination Surveys dataset. Poisson...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2019.03.001

    authors: Wong JJ,Hood KK,Breland JY

    更新日期:2019-04-01 00:00:00

  • miR-221-3p and miR-222-3p downregulation promoted osteogenic differentiation of bone marrow mesenchyme stem cells through IGF-1/ERK pathway under high glucose condition.

    abstract:OBJECTIVE:This study aims to investigate the roles of miR-221-3p and miR-222-3p in the regulation of osteogenic differentiation of bone marrow mesenchyme stem cells (BMSCs) under high glucose condition. MATERIALS AND METHODS:The expreesions of miR-221-3p, miR-222-3p and insulin-like growth factor 1 (IGF-1) were detect...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2020.108121

    authors: Gan K,Dong GH,Wang N,Zhu JF

    更新日期:2020-09-01 00:00:00

  • Challenges associated with treating children with diabetes in Saudi Arabia.

    abstract:BACKGROUND:Type 1 Diabetes Mellitus (T1DM) patients among the children have been increasing rapidly in the recent years in Saudi Arabia, as a result there is a need for extensive research in this area. Various suggestions were kept forward including m-health technologies, telemedicine etc. However, very little research...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2016.08.015

    authors: Alotaibi M,Alibrahim L,Alharbi N

    更新日期:2016-10-01 00:00:00

  • Achievement of metabolic control goals set by the American Diabetes Association and the International Society for Pediatric and Adolescent Diabetes in pediatric patients with type 1 diabetes from Spain.

    abstract:AIM:The "T1D Exchange Clinic Registry" of 13.316 pediatric patients with type 1 diabetes (T1D) in U.S. recently revealed that most children have HbA1c values above target levels established by the American Diabetes Association (ADA) and the International Society for Pediatric and Adolescent Diabetes (ISPAD). The aim of...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2014.08.033

    authors: Enes P,Martín-Frías M,Álvarez MÁ,Yelmo R,Alonso M,Barrio R

    更新日期:2015-02-01 00:00:00

  • Predicting long-term glycemic control of post-educational type II diabetic patients by evaluating serum 1,5-anhydroglucitol levels.

    abstract::1,5-Anhydroglucitol (1.5-AG) is known to closely reflect diabetic control within several days. The possibility of predicting long-term glycemic control after an educational hospitalization of type II diabetic patients was investigated by examining the relationship between changes in serum 1,5-AG levels after a short-t...

    journal_title:Diabetes research and clinical practice

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0168-8227(96)01340-x

    authors: Sone H,Okuda Y,Yamaoka T,Kawakami Y,Odawara M,Matsushima T,Kawai K,Yamashita K

    更新日期:1996-10-01 00:00:00

  • Saxagliptin is similar in glycaemic variability more effective in metabolic control than acarbose in aged type 2 diabetes inadequately controlled with metformin.

    abstract::This study compared the effects on glycaemic variability and glucose control between saxagliptin and acarbose as add-on therapies for aged T2DM inadequately controlled with metformin alone. The results showed that compared with acarbose-metformin, saxagliptin-metformin was more effective in glucose control with simila...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.diabres.2015.02.022

    authors: Wang MM,Lin S,Chen YM,Shu J,Lu HY,Zhang YJ,Xie RY,Zeng LY,Mu PW

    更新日期:2015-06-01 00:00:00

  • Endothelial dysfunction of coronary arteries in subjects without diabetes: An association with both insulin resistance and impaired insulin secretion response.

    abstract:AIMS:This study was aimed to compare insulin sensitivity and secretion response, lipoprotein and plasminogen activator inhibitor 1 (PAI-1) levels between the subjects with and without coronary artery endothelial dysfunction (ED). METHODS:ED was detected by intracoronary injection of acetylcholine (ACh) in 47 nondiabet...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2018.03.005

    authors: Lalić K,Nedeljković M,Jotić A,Babić R,Rajković N,Popović L,Lukić L,Miličić T,Singh Lukač S,Stošić L,Maćešić M,Rasulić I,Gajović JS,Lalić NM

    更新日期:2018-05-01 00:00:00

  • Dyslipidemia in diabetes mellitus.

    abstract::Patients with diabetes mellitus have a higher rate of mortality than the general population. This higher mortality may be attributed mainly to cardiovascular disease. A high prevalence of dyslipidemia in diabetics can be one of the reasons for this. The most commonly recognized lipid abnormality in non-insulin-depende...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,评审

    doi:10.1016/0168-8227(96)01263-6

    authors: Yoshino G,Hirano T,Kazumi T

    更新日期:1996-06-01 00:00:00

  • Documenting and visualising progress towards Universal Health Coverage of insulin and blood glucose test strips for people with diabetes.

    abstract:AIMS:Global governments have committed to achieve Universal Health Coverage (UHC), ensuring access to quality and affordable healthcare for all. This is fundamental for those with type 1 diabetes mellitus, who require daily access to both insulin and blood glucose test strips to survive. This group risks being left beh...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2019.107859

    authors: Klatman EL,McKee M,Ogle GD

    更新日期:2019-11-01 00:00:00

  • LDL-apheresis contributes to survival extension and renal function maintenance of severe diabetic nephropathy patients: a retrospective analysis.

    abstract:AIMS:Low-density lipoprotein (LDL)-apheresis removes various molecules including LDL/oxidized LDL and inflammatory cytokines and recovers clinical laboratory parameters. It is not yet known whether these advantages of LDL-apheresis improve the prognosis of patients with diabetic nephropathy accompanied by nephrotic syn...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2014.08.012

    authors: Sato E,Amaha M,Nomura M,Matsumura D,Ueda Y,Nakamura T

    更新日期:2014-11-01 00:00:00

  • Triple therapy combinations for the treatment of type 2 diabetes - A network meta-analysis.

    abstract:AIM:To estimate and compare the results from all randomised trials of triple combinations of anti-diabetes therapies that reported the reduction of glycated haemoglobin (HbA1c) and associated effects on body weight and hypoglycaemia. METHODS:PubMed and the Cochrane Library were searched for trials with at least one st...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.diabres.2016.04.037

    authors: Lee CM,Woodward M,Colagiuri S

    更新日期:2016-06-01 00:00:00

  • Glycemic control and its correlates in patients with diabetes in Venezuela: results from a nationwide survey.

    abstract:AIMS:To determine the prevalence of inadequate glycemic control and its correlates in a large multicenter survey of Venezuelan patients with diabetes. METHODS:A cross-sectional study in a sample of adult patients with diabetes, attending health centers in Venezuela. Information about diabetes, current medications, com...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.diabres.2009.12.014

    authors: Moreira ED Jr,Neves RC,Nunes ZO,de Almeida MC,Mendes AB,Fittipaldi JA,Ablan F,Venezuelan Diabetes Investigators' Group.

    更新日期:2010-03-01 00:00:00

  • Trends in utilization and outcomes of bariatric surgery in obese people with and without type 2 diabetes in Spain (2001-2010).

    abstract:AIM:Bariatric surgery is associated with a significant improvement in glucose control and even diabetes remission. There are no studies investigating national trends in the use of bariatric surgery in people with type 2 diabetes. We examine trends in the use of bariatric surgery in patients with and without type 2 diab...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2012.12.011

    authors: Lopez-de-Andres A,Jiménez-García R,Hernández-Barrera V,Gil-de-Miguel A,Jiménez-Trujillo MI,Carrasco-Garrido P

    更新日期:2013-03-01 00:00:00

  • Prevalence of chronic complications in Japanese diabetic patients.

    abstract::In November 1990, we carried out a survey of chronic complications of diabetes in more than 2000 diabetic patients who were seen on one day in 35 medical institutions including university hospitals, other hospitals and small clinics. More than 60% were aged 55-74 years. About 7% of patients had IDDM. Hypertension was ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(94)90244-5

    authors: Kuzuya T,Akanuma Y,Akazawa Y,Uehata T

    更新日期:1994-10-01 00:00:00

  • Effect of different glucose-lowering therapies on cancer incidence in type 2 diabetes: An observational population-based study.

    abstract:AIM:To assess the effect of metformin on cancer incidence in type 2 diabetes (T2DM), considering possible interactions with other glucose-lowering drugs and diabetes duration. METHODS:Study cohort included diabetes patients aged 20-84 on December 2009, still alive and resident in Reggio Emilia province as of December ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,评审

    doi:10.1016/j.diabres.2018.04.036

    authors: Vicentini M,Ballotari P,Giorgi Rossi P,Venturelli F,Sacchettini C,Greci M,Mangone L,Pezzarossi A,Manicardi V

    更新日期:2018-09-01 00:00:00

  • Association of the DDAH2 gene polymorphism with type 2 diabetes and hypertension.

    abstract:AIMS:The aim of this study was to investigate whether the polymorphism of DDAH2 is associated with type 2 diabetes and hypertension in Korean population. METHODS:Total 605 subjects were included in this study: 403 patients with type 2 diabetes and 202 non-diabetic control subjects. The SNP rs805304 and rs2272592 in DD...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2012.04.015

    authors: Seo HA,Kim SW,Jeon EJ,Jeong JY,Moon SS,Lee WK,Kim JG,Lee IK,Park KG

    更新日期:2012-10-01 00:00:00

  • An immunopotentiator of beta-1,6;1,3 D-glucan prevents diabetes and insulitis in BB rats.

    abstract::The preventive effect of an immunopotentiator, beta-1,6;1,3 D-glucan, on the development of diabetes and insulitis was studied in BB rats. The intravenous administration of 1 mg kg-1 week-1 of beta-1,6;1,3 D-glucan from the age of 4 weeks decreased the cumulative incidence of diabetes from 43.3% (13/30) to 6.7% (2/30)...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(92)90152-h

    authors: Kida K,Inoue T,Kaino Y,Goto Y,Ikeuchi M,Ito T,Matsuda H,Elliott RB

    更新日期:1992-08-01 00:00:00

  • A report on the diagnosis of intermediate hyperglycemia in Korea: A pooled analysis of four community-based cohort studies.

    abstract::Many studies show poor agreement between fasting plasma glucose (FPG)-based and 2-h postchallenge glucose (2-h PG)-based criteria to assess glucose metabolism. We examined the rate of agreement between FPG- and 2-h PG-based criteria in the diagnosis of intermediate hyperglycemia in four representative cohort studies i...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.diabres.2008.01.022

    authors: Oh JY,Lim S,Kim DJ,Kim NH,Kim DJ,Moon SD,Jang HC,Cho YM,Song KH,Ahn CW,Sung YA,Park JY,Shin C,Lee HK,Park KS,Committee of the Korean Diabetes Association on the Diagnosis and Classification of Diabetes Mellitus.

    更新日期:2008-06-01 00:00:00

  • A 15 year follow-up study of patients with non-insulin dependent diabetes mellitus (NIDDM) in Osaka, Japan. Long-term prognosis and causes of death.

    abstract::A 15 year follow-up study of diabetic patients was performed in Osaka, Japan. The subjects studied were 1939 patients with non-insulin dependent diabetes mellitus (NIDDM), of whom 1000 (51.5%) were alive, 880 (45.4%) had died and 59 (3.0%) were untraceable at the end of 1993. The mortality rate per 1000 person-years o...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(96)01329-0

    authors: Sasaki A,Uehara M,Horiuchi N,Hasegawa K,Shimizu T

    更新日期:1996-09-01 00:00:00

  • Diabetic damage of selective renal reabsorption assessed by albumin negative charge.

    abstract::To clarify the pathogenesis of diabetic albuminuria at its onset, the percentage of glycated albumin (%G-albumin) in excreted urinary albumin and its negative charge were assayed. In non-diabetic albuminuria (control-A) group, the high ratio of urinary %G-albumin to serum %G-albumin (urine/serum ratio of %G-albumin) s...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(96)01296-x

    authors: Kunika K,Yamaoka T,Itakura M

    更新日期:1996-08-01 00:00:00