Association of the DDAH2 gene polymorphism with type 2 diabetes and hypertension.

abstract：BACKGROUND:The relation between diabetes mellitus (DM) and mortality among patients with acute myocardial infarction is still controversial. We evaluated the influence of DM on the in-hospital mortality of acute myocardial infarction (AMI) patients using data from the Tokai Acute Myocardial Infarction Study-II, a multi...

journal_title：Diabetes research and clinical practice

authors： Hirakawa Y,Masuda Y,Kuzuya M,Iguchi A,Kimata T,Uemura K

更新日期：2007-01-01 00:00:00

abstract：:Previous studies have established that impaired glucose tolerance (IGT) patients with fasting hyperglycemia (IGT/FH: fasting plasma glucose (FPG) level 6.1-7.0 mmol/l and 2 h PG level of 7.8-11.1 mmol/l) exhibit higher insulin resistance than those with isolated IGT (FPG level <6.1 mmol/l and 2 h PG level of 7.8-11.1 ...

journal_title：Diabetes research and clinical practice

authors： Suzuki H,Fukushima M,Usami M,Ikeda M,Taniguchi A,Nakai Y,Matsuura T,Yasuda K,Hosokawa M,Seino Y,Yamada Y

更新日期：2004-06-01 00:00:00

abstract：:The aim of this multicentre study was to investigate the effect--in everyday life--of long term administration of acarbose on parameters of glycaemic control, daily insulin requirements, lipid parameters and tolerability in ambulant type 1 diabetic subjects insufficiently controlled with diet and insulin. Furthermore,...

journal_title：Diabetes research and clinical practice

authors： Sels JP,Verdonk HE,Wolffenbuttel BH

更新日期：1998-08-01 00:00:00

abstract：:Non-specific aggression to endocrine alpha and beta cells as well as exocrine pancreas has been suggested in fulminant type 1 diabetes (FT1DM), while its effect on glucagon secretion and exocrine function is unknown. Here, we report a FT1DM case with exocrine pancreatic insufficiency and enhanced glucagon response to ...

journal_title：Diabetes research and clinical practice

authors： Yabe D,Kuroe A,Ohya M,Watanabe K,Kitatani N,Oku M,Kurose T,Seino Y

更新日期：2008-11-01 00:00:00

abstract：AIM:To examine the effect of oral diabetes medication on the risk of dementia in an elderly cohort with type 2 diabetes. METHODS:This was a population-based cohort study using the Korean National Health Insurance claims data from 2002 to 2013. Elderly subjects (60 years of age or older) with and without type 2 diabete...

journal_title：Diabetes research and clinical practice

authors： Kim JY,Ku YS,Kim HJ,Trinh NT,Kim W,Jeong B,Heo TY,Lee MK,Lee KE

更新日期：2019-08-01 00:00:00

abstract：:Self-monitoring of blood glucose (SMBG) in type 2 diabetic patients was compared across 14 countries. There was an unexpectedly high SMBG-use in non-insulin-treated patients. Reimbursement polices differed by country, region, insurance status, and patient income. More rigorous and systematic data collection is needed ...

journal_title：Diabetes research and clinical practice

authors： SMBG International Working Group.

更新日期：2008-12-01 00:00:00

abstract：:Recent clinical and experimental studies have suggested that diabetic patients may develop myocardial dysfunction in the absence of coronary heart disease and hypertension. In this study, the correlation between histopathological changes and myocardial dysfunction was studied in experimental diabetic rat hearts. Male ...

journal_title：Diabetes research and clinical practice

authors： Kita Y,Shimizu M,Sugihara N,Shimizu K,Yoshio H,Shibayama S,Takeda R

更新日期：1991-03-01 00:00:00

abstract：:We studied cognition in the Finnish Diabetes Prevention Study (DPS), a trial of lifestyle intervention that prevented diabetes in persons with impaired glucose tolerance. Cognition was similar in the randomization arms 9 years after the intervention in 364 participants, suggesting that the intervention did not benefit...

journal_title：Diabetes research and clinical practice

authors： Luchsinger JA,Lehtisalo J,Lindström J,Ngandu T,Kivipelto M,Ahtiluoto S,Ilanne-Parikka P,Keinänen-Kiukaanniemi S,Eriksson JG,Uusitupa M,Tuomilehto J,Finnish Diabetes Prevention Study (DPS).

更新日期：2015-06-01 00:00:00

abstract：AIMS:Body-weight fluctuation is associated with an increased risk of all-cause mortality. Yet no studies investigate its association with risk of diabetes in adults aged ≥ 60 years. This study aimed to address this issue. METHODS:A total of 1,565 participants free of diabetes at baseline in the CHARLS were followed fo...

journal_title：Diabetes research and clinical practice

authors： Cai X,Qiu S,Liu S,Lu Y,Luo D,Li R,Li M

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Islet autoimmunity, age at onset and time to insulin treatment are often used to define subgroups of diabetes. However, the latter criterion is not clinical useful. Here, we examined whether an unbiased stratification of diabetes according to age at onset, fasting C-peptide and GAD autoantibodies (GADab) defi...

journal_title：Diabetes research and clinical practice

authors： Wod M,Yderstræde KB,Halekoh U,Beck-Nielsen H,Højlund K

更新日期：2017-12-01 00:00:00

abstract：INTRODUCTION:Diabetic cardiac autonomic neuropathy (CAN) is potentially life threatening and its severity might further be aggravated by poor glycaemic control. A decrease in Heart rate variability (HRV) is the earliest finding of CAN even at the sub clinical stage. While intensive glycaemic control prevents the develo...

journal_title：Diabetes research and clinical practice

authors： Mba CM,Nganou-Gnindjio CN,Azabji-Kenfack M,Mfeukeu-Kuate L,Dehayem MY,Mbanya JC,Sobngwi E

更新日期：2019-11-01 00:00:00

abstract：:Prevalence of MODY2 and MODY3 mutations has been assessed in 23 Brazilian families with MODY phenotype. Mutations in HNF-1alpha have been found in 3 families (13%) and 2 families (8.7%) had new glucokinase mutations. These genes do not explain the majority of MODY cases in Brazilian population. ...

journal_title：Diabetes research and clinical practice

authors： Furuzawa GK,Giuffrida FM,Oliveira CS,Chacra AR,Dib SA,Reis AF

更新日期：2008-09-01 00:00:00

abstract：:The prevalence of increased urinary albumin excretion (UAE) (micro- and macroalbuminuria) and its association with diabetic retinopathy (DR) (evaluated by fluorescent angiography), coronary heart disease (CHD), and various related risk factors were studied in 320 type 2 diabetic patients. In this subsample of type 2 d...

journal_title：Diabetes research and clinical practice

authors： Lunetta M,Infantone L,Calogero AE,Infantone E

更新日期：1998-04-01 00:00:00

abstract：:Vascular complications are the leading cause of morbidity and mortality in patients with diabetes. Four main molecular mechanisms have been implicated in glucose-mediated vascular disease. There are: glucose-induced activation of protein kinase C (PKC) isoforms; increased formation of glucose-derived advanced glycatio...

journal_title：Diabetes research and clinical practice

authors： Nishikawa T,Kukidome D,Sonoda K,Fujisawa K,Matsuhisa T,Motoshima H,Matsumura T,Araki E

更新日期：2007-09-01 00:00:00

abstract：:The effect of insulin on the serum levels of the amino-terminal propeptide of type III procollagen (PIIINP) was investigated in patients with non-insulin-dependent diabetes mellitus, whose disease was unsatisfactorily controlled by oral drugs. Before insulin therapy the PIIINP values of the patients (3.2 +/- 1.3 micro...

journal_title：Diabetes research and clinical practice

authors： Sotaniemi EA,Stenbäck FG,Risteli L,Vuori JA,Rautio A,Huupponen R,Risteli J

更新日期：1992-09-01 00:00:00

abstract：:To elucidate the relationship between carnitine metabolism and plasma ketone body concentrations in moderately obese patients with mild glucose intolerance, the ketone body and carnitine levels in the basal state were determined in 72 obese patients: 20 with normal glucose tolerance (NGT), 29 with impaired glucose tol...

journal_title：Diabetes research and clinical practice

authors： Inokuchi T,Imamura K,Nomura K,Nomoto K,Isogai S

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:To compare the prevalence of the Metabolic Syndrome (MetS) defined by four definitions and to determine which definition best identifies those at high cardiovascular disease (CVD) risk and with insulin resistance. METHODS:AusDiab is a population-based survey of 11,247 Australians. Participants had anthropome...

journal_title：Diabetes research and clinical practice

authors： Cameron AJ,Magliano DJ,Zimmet PZ,Welborn T,Shaw JE

更新日期：2007-09-01 00:00:00

abstract：:The effect of long-term (6 months) administration of voglibose in a dietary mixture (10 ppm) on intestinal disaccharidase activity was examined in non obese type 2 diabetes model Goto-Kakizaki (GK) rats. The postprandial blood glucose level in voglibose-treated GK rats was significantly lower than in untreated GK rats...

journal_title：Diabetes research and clinical practice

authors： Yasuda K,Shimowada K,Uno M,Odaka H,Adachi T,Shihara N,Suzuki N,Tamon A,Nagashima K,Hosokawa M,Tsuda K,Seino Y

更新日期：2003-02-01 00:00:00

abstract：:The aim of this study was to examine distinctive clinical characteristics of non-insulin dependent diabetes mellitus (NIDDM) patients in Kuwait including mode of presentation at diagnosis, family history of diabetes, therapeutic management and response to treatment. We studied 3299 Kuwaiti patients (1454 male (M) and ...

journal_title：Diabetes research and clinical practice

authors： Abdella NA,Khogali MM,Salman AD,Ghuneimi SA,Bajaj JS

更新日期：1995-08-01 00:00:00

abstract：:There is evidence to suggest that hyperglycemia is required for the development of the microvascular complications of diabetes. However, the precise mechanism by which hyperglycemia might cause diabetic complications is not completely clear. One possibility is the increased activity of the polyol pathway. Capillary ba...

journal_title：Diabetes research and clinical practice

authors： Ramirez LC,Arauz C,Pruneda L,Hammon K,Rosenstock J,Raskin P

更新日期：1991-02-01 00:00:00

abstract：:Glucose metabolism disturbances are frequently reported among patients with beta-thalassaemia major on conventional treatment consisted of regular blood transfusions and adequate chelation treatment. Aim of this study was to evaluate the evolution of oral glucose tolerance test (OGTT) in thalassaemic patients in relat...

journal_title：Diabetes research and clinical practice

authors： Christoforidis A,Perifanis V,Tsatra I,Vlachaki E,Athanassiou-Metaxa M

更新日期：2007-04-01 00:00:00

abstract：:To characterise the relationship between diurnal blood pressure and the subsequent increase of urinary albumin excretion (UAE) in normotensive normoalbuminuric type 1 diabetic patients, ambulatory blood pressure monitoring (ABPM) was performed in 53 patients, who were then followed for 5 years. Albumin excretion rate ...

journal_title：Diabetes research and clinical practice

authors： Lengyel Z,Rosivall L,Németh C,Tóth LK,Nagy V,Mihály M,Kammerer L,Vörös P

更新日期：2003-12-01 00:00:00

abstract：:Amputation has been known to be a rare adverse event of sodium glucose co-transporter-2 (SGLT2) inhibitors. It remains unclear whether the SGLT2 inhibitor as a class or specific categories of the SGLT2 inhibitors are linked with an increased risk of amputation. The objective of this meta-analysis was to investigate th...

journal_title：Diabetes research and clinical practice

authors： Miyashita S,Kuno T,Takagi H,Sugiyama T,Ando T,Valentin N,Shimada YJ,Kodaira M,Numasawa Y,Kanei Y,Bangalore S

更新日期：2020-05-01 00:00:00

abstract：:Aldose reductase (AR) protein was measured in peripheral mononuclear cells (PMCs) from 55 patients with type 2 diabetes by a two-site ELISA using anti-human AR monoclonal antibody. AR levels did not correlate with age, duration of diabetes, and HbAlc. Furthermore, no significant differences were found in AR levels bet...

journal_title：Diabetes research and clinical practice

authors： Hasegawa G,Obayashi H,Kitamura A,Hashimoto M,Shigeta H,Nakamura N,Kondo M,Nishimura CY

更新日期：1999-08-01 00:00:00

abstract：AIM:To identify characteristics of neuropsychological function among elderly individuals with Type 2 diabetes mellitus with mild cognitive impairment (T2DM-MCI) and evaluate domain-specific effects of T2DM on cognition. METHODS:This was a cross-sectional study conducted in Tianjin, China. MCI subjects (n=246) and cont...

journal_title：Diabetes research and clinical practice

authors： Gao Y,Xiao Y,Miao R,Zhao J,Zhang W,Huang G,Ma F

更新日期：2015-08-01 00:00:00

abstract：:A hypothesis that mitochondrial genome itself is the thrifty genome has been advanced, as both its mutation, or quality, and amount in the peripheral blood, or quantity, are found to have close relationship to diabetes mellitus, or more specifically insulin resistance. Mere presence of relationship, however, does not ...

journal_title：Diabetes research and clinical practice

authors： Lee HK

更新日期：2001-12-01 00:00:00

abstract：:The patient was a 56-year-old man with type 2 diabetes and insulin allergy. He was administered glargine, which did not produce any allergic reactions, except for a small non-pruritic wheal. Thereafter, other insulin preparation could be administered. We consider this the first case of successful insulin desensitizati...

journal_title：Diabetes research and clinical practice

authors： Hara M,Izumida Y,Sato N,Ohashi K,Osuga J,Tobe K,Tsukamoto K,Kadowaki T

更新日期：2009-06-01 00:00:00

abstract：:Sanguis draxonis (SD) is a Chinese traditional herb that is prescribed for the handling of diabetic disorders. In this study, the effects of an oral administration of SD at dosages of 100, 300, and 500 mg kg(-1) once a day, respectively, on the formation of insulin resistance were investigated in vivo in two models of...

journal_title：Diabetes research and clinical practice

authors： Hou Z,Zhang Z,Wu H

更新日期：2005-04-01 00:00:00

abstract：AIMS:Media calcification is a predictor of cardiovascular mortality in type 2 diabetes mellitus (T2DM). Undercarboxylation of some vitamin K-dependent proteins, due to genetic polymorphisms of VKORC1, can lead to calcification. We examined a potential association between VKORC1 -1639 G>A polymorphism and T2DM and, also...

journal_title：Diabetes research and clinical practice

authors： Tavridou A,Petridis I,Vasileiadis M,Ragia G,Heliopoulos I,Vargemezis V,Manolopoulos VG

更新日期：2011-11-01 00:00:00

abstract：:Activity of the lower leg muscles in response to an unexpected disturbance to upright standing was studied in diabetic patients and non-diabetic matched controls. The diabetic individuals were classified into two groups: diabetic patients with normal cutaneous sensitivity in the foot (n=27) and patients with cutaneous...

journal_title：Diabetes research and clinical practice

authors： Simmons RW,Richardson C

更新日期：2001-07-01 00:00:00