Influence of diabetes mellitus on in-hospital mortality in patients with acute myocardial infarction in Japan: a report from TAMIS-II.


BACKGROUND:The relation between diabetes mellitus (DM) and mortality among patients with acute myocardial infarction is still controversial. We evaluated the influence of DM on the in-hospital mortality of acute myocardial infarction (AMI) patients using data from the Tokai Acute Myocardial Infarction Study-II, a multi-hospital prospective study performed in Japan. METHODS:All of the study subjects were patients hospitalized for newly diagnosed AMI at 1 of 13 acute care hospitals between January of 2001 and December of 2003. We abstracted the baseline and procedural characteristics from detailed chart reviews. Multivariate analysis was performed, controlling for the variables found to be significantly different between AMI patients with and without DM by chi-square test or unpaired t-test. We evaluated a total of 940 DM and 2284 non-DM patients. RESULTS:DM patients had roughly twice the in-hospital mortality rate of non-DM patients, with an unadjusted odds ratio of 1.77 (95% CI, 1.37-2.30). However, according to the multivariate analysis, DM was not identified as an independent predictor of in-hospital death, with an adjusted odds ratio of 5.73 (95% CI, 0.97-33.88). CONCLUSIONS:DM is not an independent predictor of in-hospital mortality, and that there is a need for additional studies to confirm our conclusion.


Hirakawa Y,Masuda Y,Kuzuya M,Iguchi A,Kimata T,Uemura K




Has Abstract


2007-01-01 00:00:00














  • Metabolic syndrome in relationship to type 2 diabetes and atherosclerosis.

    abstract::Metabolic syndrome affects approximately one quarter of population in developed countries. Its presence is a major risk for development of both type 2 diabetes (T2DM) and atherosclerosis. The prevalence of cardiovascular disease is 2-3 times higher in individuals with metabolic syndrome than in age-matched controls. M...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,评审


    authors: Tkác I

    更新日期:2005-06-01 00:00:00

  • Glycaemia and utilisation of technology across the lifespan of adults with type 1 diabetes: Results of the Australian National Diabetes Audit (ANDA).

    abstract:AIMS:To evaluate the utilisation of technologies and associated glycaemia among adults with type 1 diabetes. METHODS:De-identified data from adults with type 1 diabetes (≥18 years old) in the Australian National Diabetes Audit (ANDA)-2019 were analysed. Proportions using insulin pumps or injections with continuous glu...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Pease A,Szwarcbard N,Earnest A,Andrikopoulos S,Wischer N,Zoungas S

    更新日期:2020-12-10 00:00:00

  • The 3C study: coverage cost and care of type 1 diabetes in China--study design and implementation.

    abstract:AIM:To describe coverage, cost and care of type 1 diabetes (T1D) in 2 regions of China--Beijing and Shantou--including: METHODS:This is a mixed-methods descriptive study with three arms--coverage, cost and care. It is taking place in 4 tertiary hospitals, 3 secondary hospitals and 4 primary health facilities in Beijin...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究


    authors: McGuire H,Kissimova-Skarbek K,Whiting D,Ji L

    更新日期:2011-11-01 00:00:00

  • Reduced lung diffusion capacity in type 2 diabetes is independent of heart failure.

    abstract::In a case-control analysis comparing 303 patients with diabetes and 303 without (matched on age, race, sex and height), diabetics had reduced lung diffusion (DLCO) independent of smoking, obesity, clinical heart failure, asymptomatic left ventricular systolic and diastolic dysfunction: DLCO (mean±SE: 15.5±0.9 vs. 16.4...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Klein OL,Jones M,Lee J,Collard HR,Smith LJ

    更新日期:2012-06-01 00:00:00

  • Design and development of the Hypoglycaemia Symptom Rating Questionnaire (HypoSRQ).

    abstract:AIMS:To evaluate the Hypoglycaemia Symptom Rating Questionnaire (HypoSRQ©) and relationships between self-reported hypoglycaemia and hypoglycaemia measured using blinded continuous glucose monitoring (CGM). METHODS:Diabetes outpatients (n = 113) recruited from Ashford and St. Peter's Hospital completed the HypoSRQ (re...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Taylor MD,Han TS,Ward H,Bradley C

    更新日期:2019-05-01 00:00:00

  • Insulin autoantibodies in patients with autoimmune diseases.

    abstract::Insulin antibodies (IAA) can be detected in the serum of the majority of newly diagnosed IDDM patients prior to insulin therapy. In first degree relatives of IDDM patients, IAA are associated with an increased risk of development of IDDM. However, the disease specificity of IAA, detected by radiobinding assays, has no...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Harrop M,Caudwell J,Stojanovski C,Colman PG

    更新日期:1992-11-01 00:00:00

  • Glycemic control and its correlates in patients with diabetes in Venezuela: results from a nationwide survey.

    abstract:AIMS:To determine the prevalence of inadequate glycemic control and its correlates in a large multicenter survey of Venezuelan patients with diabetes. METHODS:A cross-sectional study in a sample of adult patients with diabetes, attending health centers in Venezuela. Information about diabetes, current medications, com...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究


    authors: Moreira ED Jr,Neves RC,Nunes ZO,de Almeida MC,Mendes AB,Fittipaldi JA,Ablan F,Venezuelan Diabetes Investigators' Group.

    更新日期:2010-03-01 00:00:00

  • Further evidence for insulin hypersecretion not as an initial event but as a consequence of body growth and maturation in juvenile-onset obesity.

    abstract::According to our previous study, hyperinsulinism develops not before 10 years of age despite the presence of obesity but during the maturation years of 10-20. We aimed here at examining the growth-related islet B-cell change together with pituitary activity in non-familial juvenile obesity. Measurement of 24 h urine h...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Maruhama Y,Hikichi I,Hashimoto T,Saito F,Ninomiya K

    更新日期:1986-05-01 00:00:00

  • Relationship of abdominal fat with metabolic disorders in diabetes mellitus patients.

    abstract::In this study, we examined the relationships of the fat distribution with the clinical parameters, microangiopathy, and coagulation disorders in Japanese diabetic patients, distinguishing between males and females. To investigate these relationships, the clinical parameters of the patients were compared with the total...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Asakawa H,Tokunaga K,Kawakami F

    更新日期:2002-02-01 00:00:00

  • Peripheral vascular reactions to smoking--profound vasoconstriction by atherosclerosis.

    abstract::Analyses of direct effects of smoking on peripheral arteries were done using thermography, blood fluorometry and echography on 97 habitual smoker-diabetics without triopathy. There were found to be four types of thermographic changes following smoking, which varied according to the degree of atherosclerosis of the art...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Fushimi H,Kubo M,Inoue T,Yamada Y,Matsuyama Y,Kameyama M

    更新日期:1998-10-01 00:00:00

  • Diabetes-related renal growth and IGF-I accumulation in castrated rats.

    abstract::The effects of castration on diabetes-related renal growth and IGF-I regulation were studied. In the rat, prepubertal castration is associated with a normal or increased surge in plasma insulin-like growth factor I (IGF-I) at the time of 'puberty'. In order to determine the role of sex steroids in the development of d...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Bach LA,Cox AJ,Jerums G

    更新日期:1991-10-01 00:00:00

  • Health education on diabetes and other non-communicable diseases imparted to teachers shows a cascading effect. A study from Southern India.

    abstract:AIMS:The aims were to assess effect of a short training programme on non-communicable diseases (NCDs), particularly diabetes on school teachers and also on students who were in turn educated by them. Lifestyle changes made by both groups were assessed 6months later. METHODS:Graduate teachers (n=1017) from 2 districts ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Selvam S,Murugesan N,Snehalatha C,Nanditha A,Raghavan A,Simon M,Susairaj P,Ramachandran A

    更新日期:2017-03-01 00:00:00

  • Lower limb arterio-venous shunts, autonomic neuropathy and diabetic foot.

    abstract::We have quantitatively assessed the percentage of lower limb arterio-venous (a-v) shunting using a radioisotopic technique and correlated it with autonomic neuropathy evaluated by cardiovascular tests. We have studied three groups of diabetic patients: Group A, 12 non-neuropathic subjects without foot lesions; Group B...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Uccioli L,Mancini L,Giordano A,Solini A,Magnani P,Manto A,Cotroneo P,Greco AV,Ghirlanda G

    更新日期:1992-05-01 00:00:00

  • Relation of habitual snoring with components of metabolic syndrome in Korean adults.

    abstract:AIMS:To examine the association between habitual snoring and components of the metabolic syndrome in Korean adults. Whether these associations are independent of obesity was also explored. METHODS:Four thousand five hundred and six men and 5041 women aged 40-69 years from the Korean Health and Genome Study were examin...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究


    authors: Cho N,Joo S,Kim J,Abbott RD,Kim J,Kimm K,Shin C

    更新日期:2006-03-01 00:00:00

  • Is the metabolic syndrome inversely associates with butter, non-hydrogenated- and hydrogenated-vegetable oils consumption: Tehran lipid and glucose study.

    abstract:AIM:The aim of this study was to investigate the association between hydrogenated- (HVOs) and non-hydrogenated vegetable oils (non-HVOs) and butter and the metabolic syndrome (MetS) after 3-years of follow-up in adults. METHODS:This study was conducted between 2006-2008 and 2009-2011 within the framework of the Tehran...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Hosseinpour-Niazi S,Mirmiran P,Hosseini-Esfahani F,Azizi F

    更新日期:2016-02-01 00:00:00

  • Dropout of young non-insulin-dependent diabetics from diabetic care.

    abstract::We investigated the follow-up status and prognosis of 109 patients with non-insulin-dependent diabetes mellitus aged from 10 to 19 years old (66 males and 43 females). Patients who had not attended hospital for at least 20 months up to the end of September 1990 were regarded as defaulters, and were surveyed by questio...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Kawahara R,Amemiya T,Yoshino M,Miyamae M,Sasamoto K,Omori Y

    更新日期:1994-07-01 00:00:00

  • Effect of moderate-intensity exercise training on GDNF signaling pathway in testicles of rats after experimental diabetes type 1 induction.

    abstract:AIMS:The spermatogenesis failure is reported as the main complication for diabetes and the moderate-intensity exercise (EX) is shown to ameliorate the diabetes-induced impairments both at spermatogenesis and sperm levels. Thus, the current study was done to investigate the possible effect of EX in the sole and simultan...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Samadian Z,Tofighi A,Razi M,Ghaderi Pakdel F,Tolouei Azar J

    更新日期:2020-09-01 00:00:00

  • Trends in deliveries in women with gestational diabetes in Spain, 2001-2008.

    abstract::We examined trends and characteristics of deliveries in women with gestational diabetes in Spain from 2001 to 2008. There were 101,643 deliveries with gestational diabetes among 2,782,369 delivery discharges (3.6%) with no increase over time. Rate of caesarean section increased (19-24.2%) and length of stay decreased....

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Lopez-de-Andres A,Carrasco-Garrido P,Gil-de-Miguel A,Hernandez-Barrera V,Jiménez-García R

    更新日期:2011-02-01 00:00:00

  • Health-related quality-of-life implications of cardiovascular events in individuals with type 2 diabetes mellitus: A subanalysis from the Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus (SAVOR)-TIMI 53 trial.

    abstract:BACKGROUND:The impact of cardiovascular complications on health-related quality-of-life (HRQoL) in type 2 diabetes mellitus has not been clearly established. Using EQ5D utility data from SAVOR-TIMI 53, a large phase IV trial of saxagliptin versus placebo, we quantified the impact of cardiovascular and other major event...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Briggs AH,Bhatt DL,Scirica BM,Raz I,Johnston KM,Szabo SM,Bergenheim K,Mukherjee J,Hirshberg B,Mosenzon O

    更新日期:2017-08-01 00:00:00

  • The burden of diabetes and impaired glucose tolerance in India using the WHO 1999 criteria: prevalence of diabetes in India study (PODIS).

    abstract::This random multistage cross-sectional population survey was undertaken to determine the prevalence of diabetes mellitus (DM) and impaired glucose tolerance (IGT) in subjects aged 25 years and above in India. The study was carried out in 77 centers (40 urban and 37 rural). 18363 (9008 males and 9355 females) subjects ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Sadikot SM,Nigam A,Das S,Bajaj S,Zargar AH,Prasannakumar KM,Sosale A,Munichoodappa C,Seshiah V,Singh SK,Jamal A,Sai K,Sadasivrao Y,Murthy SS,Hazra DK,Jain S,Mukherjee S,Bandyopadhay S,Sinha NK,Mishra R,Dora M,Je

    更新日期:2004-12-01 00:00:00

  • Glucose fluctuation and the resultant endothelial injury are correlated with pancreatic β cell dysfunction in patients with coronary artery disease.

    abstract:AIMS:We evaluated whether glucose fluctuation (GF) causes vascular endothelial injury and affects glucometabolic factors during lengthy oral glucose tolerance test (OGTT). METHODS:We enrolled consecutive 116 patients with coronary artery disease (CAD) who were performed coronary angiography and 4-h OGTT. Blood samples...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Murata M,Adachi H,Oshima S,Kurabayashi M

    更新日期:2017-09-01 00:00:00

  • Diabetes in the Africa Region: an update.

    abstract::The Africa Region (AFR), where diabetes was once rare, has witnessed a surge in the condition. Estimates for type 1 diabetes suggest that about 39,000 people suffer from the disease in 2013 with 6.4 new cases occurring per year per 100,000 people in children <14 years old. Type 2 diabetes prevalence among 20-79-year-o...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Peer N,Kengne AP,Motala AA,Mbanya JC

    更新日期:2014-02-01 00:00:00

  • Insulin resistance in Brazilian adolescent girls: association with overweight and metabolic disorders.

    abstract::We assessed the association between insulin resistance, overweight and metabolic disorders in a probabilistic sample of 388, 12-19-year-old girls from public schools in Niterói, Rio de Janeiro State, Brazil. Insulin resistance was determined using Homeostatic Model Assessment-Insulin Resistance (HOMA-IR). Overweight a...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Alvarez MM,Vieira AC,Moura AS,da Veiga GV

    更新日期:2006-11-01 00:00:00

  • Five fold increase of insulin concentration delays the absorption of subcutaneously injected human insulin suspensions in pigs.

    abstract::Human NPH U100 (100 IU/ml), given once daily, is often absorbed too fast to cover the basal insulin demand throughout 24 h. The aim of the present study was to examine whether the absorption of human insulin suspensions would be delayed by increasing the insulin concentration from U100 to U500. In each experiment 10 I...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Jørgensen KH,Hansen AK,Buschard K

    更新日期:2000-12-01 00:00:00

  • The levels of plasma growth arrest-specific protein 6 is associated with insulin sensitivity and inflammation in women.

    abstract:AIMS:Vitamin K-dependent growth arrest-specific protein 6 (Gas6) and its receptors of the TAM (TYRO-3/Axl/Mer) family are ubiquitously expressed in immune, cardiovascular, and reproductive systems. They play pivotal roles of regulating tissue homeostasis via anti-inflammatory effects. Recent studies show that the Gas6/...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Kuo FC,Hung YJ,Shieh YS,Hsieh CH,Hsiao FC,Lee CH

    更新日期:2014-02-01 00:00:00

  • The medium-term effect of natural or extractive dietary fibres on plasma amino acids and lipids in type 1 diabetics.

    abstract::We evaluated the effect of a diet rich in natural (NF) or extractive fibres (guar gum) on 12 male IDD (insulin-dependent diabetes) out-patients. The treatment lasted for 2 months. During the first month the patients were on an isocaloric diet containing 30 g of fibres and then they were randomly subdivided into two gr...

    journal_title:Diabetes research and clinical practice

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Bruttomesso D,Briani G,Bilardo G,Vitale E,Lavagnini T,Marescotti C,Duner E,Giorato C,Tiengo A

    更新日期:1989-02-15 00:00:00

  • Memory dysfunction and autonomic neuropathy in non-insulin-dependent (type 2) diabetic patients.

    abstract::Considering the nervous system as a unit, it might be expected that diabetic patients with autonomic neuropathy could have a central abnormality expressed as cognitive dysfunction. To determine whether autonomic neuropathy is independently associated with cognitive dysfunction, we studied a cross-section of 20 non-ins...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Zaslavsky LM,Gross JL,Chaves ML,Machado R

    更新日期:1995-11-01 00:00:00

  • The effects of sitagliptin, a DPP-4 inhibitor, on cognitive functions in elderly diabetic patients with or without Alzheimer's disease.

    abstract:AIMS:The present study aimed to evaluate effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor (DPP-4I), on cognitive functions in elderly diabetic patients with and without cognitive impairment. METHODS:253 elderly patients with type 2DM, were enrolled in this prospective and observational study. After comprehens...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Isik AT,Soysal P,Yay A,Usarel C

    更新日期:2017-01-01 00:00:00

  • Targeting educational interventions to clinician's stage of change.

    abstract::This before-after mixed-method study assessed the effect of a diabetes education and self-efficacy training workshop on clinician knowledge, intention and self-efficacy. This workshop demonstrated and narrowed a knowledge gap but did not change intention or self-efficacy. Neither the intervention nor the measured outc...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章


    authors: Yu CH,Batty HP

    更新日期:2010-09-01 00:00:00

  • Geographical variation in the progression of type 2 diabetes in Peru: The CRONICAS Cohort Study.

    abstract:BACKGROUND:The study aims were to estimate the incidence and risk factors for T2D in four settings with different degree of urbanization and altitude in Peru. METHODS:Prospective cohort study conducted in urban, semi-urban, and rural areas in Peru. An age- and sex-stratified random sample of participants was taken fro...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究


    authors: Bernabé-Ortiz A,Carrillo-Larco RM,Gilman RH,Miele CH,Checkley W,Wells JC,Smeeth L,Miranda JJ,CRONICAS Cohort Study Group.

    更新日期:2016-11-01 00:00:00