Natural variation in maternal care shapes adult social behavior in rats.

Abstract:

:Features of the early postnatal environment profoundly shape later physical and behavioral phenotypes. The amount of licking/grooming that rat dams direct towards their offspring has durable consequences, including behavioral and physiological dimensions of stress reactivity, cognition, and reproductive behavior. We examined how natural variation in maternal care alters social behavior in adult offspring and how this relates to anxiety behavior and oxytocin receptor density. Male and female offspring of mothers who received high levels of licking spent significantly more time in social contact with unfamiliar individuals than did offspring whose dams provided less grooming. Reduced anxiety behavior was associated with greater social interaction. No differences in oxytocin receptor binding assessed by (125) I-OVTA autoradiography were detected between groups. The present investigation characterizes a novel impact of maternal care on adult social interaction behavior, replicates anxiety behavior differences, and illustrates connections between social behavior and anxiety in adulthood across maternal treatment groups.

journal_name

Dev Psychobiol

authors

Starr-Phillips EJ,Beery AK

doi

10.1002/dev.21182

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

1017-26

issue

5

eissn

0012-1630

issn

1098-2302

journal_volume

56

pub_type

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