Abstract:
:A question still to be answered is whether ethanol initiation has a greater effect on ethanol consumption if it occurs during adolescence than in adulthood. This study assessed the effect of ethanol initiation during adolescence or adulthood on voluntary ethanol consumption when animals were still within the same age range. Adolescent or adult rats were given 5, 2, or 0 ethanol exposures. The animals were tested for ethanol consumption through two-bottle choice tests, before undergoing a 1-week deprivation. A two-bottle assessment was conducted after the deprivation. Adolescents, but not adults, given two ethanol administrations during initiation exhibited significantly higher ethanol intake during the pre-deprivation period. These adolescents also exhibited a threefold increase in ethanol intake after 7 days of drug withdrawal, when compared with controls. These findings suggest that very brief experience with binge ethanol intoxication in adolescence, but not in adulthood, impacts later predisposition to drink.
journal_name
Dev Psychobioljournal_title
Developmental psychobiologyauthors
Fabio MC,Nizhnikov ME,Spear NE,Pautassi RMdoi
10.1002/dev.21101subject
Has Abstractpub_date
2014-04-01 00:00:00pages
574-83issue
3eissn
0012-1630issn
1098-2302journal_volume
56pub_type
杂志文章abstract::The preweaning behavioral development was compared in 3 hamster species: the golden (Mesocricetus auratus), Chinese (Cricetulus griseus), and Djungarian (Phodopus sungorus). Differences in the age of appearance of action patterns could not be summarized by simply ranking species on either precocity or developmental sp...
journal_title:Developmental psychobiology
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journal_title:Developmental psychobiology
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journal_title:Developmental psychobiology
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journal_title:Developmental psychobiology
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abstract::The effects of an enriched environment (EE, permanent presence of a humanlike model plus colored mobile objects) during the rearing period (from birth to weaning at 3 months) were assessed on subsequent fear reactions of lambs and their mothers. Behavioral tests involved isolation, surprise effect, and the presence of...
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journal_title:Developmental psychobiology
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journal_title:Developmental psychobiology
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abstract::In this review, we consider the literature on sensitive periods for language acquisition from the perspective of the stroke recovery literature treated in this Special Issue. Conceptually, the two areas of study are linked in a number of ways. For example, the fact that learning itself can set the stage for future fai...
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journal_title:Developmental psychobiology
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