Abstract:
:Fear conditioning studies in adults have found that posttraumatic stress disorder (PTSD) is associated with heightened fear responses and impaired discrimination. The objective of the current study was to examine the association between PTSD symptoms and fear conditioned responses in children from a highly traumatized urban population. Children between 8 and 13 years old participated in a fear conditioning study in addition to providing information about their trauma history and PTSD symptoms. Results showed that females showed less discrimination between danger and safety signals during conditioning compared to age-matched males. In boys, intrusive symptoms were predictive of fear responses, even after controlling for trauma exposure. However, in girls, conditioned fear to the danger cue was predictive of self-blame and fear of repeated trauma. This study suggests there are early sex differences in the patterns of fear conditioning and that these sex differences may translate to differential risk for trauma-related psychopathology.
journal_name
Dev Psychobioljournal_title
Developmental psychobiologyauthors
Gamwell K,Nylocks M,Cross D,Bradley B,Norrholm SD,Jovanovic Tdoi
10.1002/dev.21313subject
Has Abstractpub_date
2015-11-01 00:00:00pages
799-808issue
7eissn
0012-1630issn
1098-2302journal_volume
57pub_type
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journal_title:Developmental psychobiology
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journal_title:Developmental psychobiology
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journal_title:Developmental psychobiology
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journal_title:Developmental psychobiology
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journal_title:Developmental psychobiology
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