Abstract:
:Intensive corticosterone treatment given to rats during the 1st postnatal week irreversibly decreases DNA accumulation in the cerebrum and cerebellum. After such hypercorticism in infancy rats were tested as adults in 2 conditioned active avoidance tasks. In comparison with litter-mate controls, the treated rats were impaired in the acquisition of 2-way active avoidance but not in the acquisition of 1-way active avoidance. These data are consistent with other observations suggesting a hyperresponsiveness or hyperemotionality following corticosterone treatment in infancy.
journal_name
Dev Psychobioljournal_title
Developmental psychobiologyauthors
Olton DS,Johnson CT,Howard Edoi
10.1002/dev.420080108subject
Has Abstractpub_date
1975-01-01 00:00:00pages
55-61issue
1eissn
0012-1630issn
1098-2302journal_volume
8pub_type
杂志文章abstract::The preweaning behavioral development was compared in 3 hamster species: the golden (Mesocricetus auratus), Chinese (Cricetulus griseus), and Djungarian (Phodopus sungorus). Differences in the age of appearance of action patterns could not be summarized by simply ranking species on either precocity or developmental sp...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420090404
更新日期:1976-07-01 00:00:00
abstract::In Experiment I, rats 13-35 days of age were presented with acoustic startle stimuli in conjunction with light flashes or noise bursts at 4-320 msec lead times. Inhibition of the startle reflex by leading noise bursts was present on Days 13-15, whereas light flashes were not effective until Days 21-23. In Experiment I...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420140403
更新日期:1981-07-01 00:00:00
abstract::It has been argued that a recently developed measure, vagal tone (V), is a significant advancement over other existing methods of assessing the periodic variation in heart rate associated with respiration (respiratory sinus arrhythmia). It has been further suggested that, as a noninvasive measure of vagal nerve effere...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420240203
更新日期:1991-03-01 00:00:00
abstract::Under standard conditions involving isolation and cooling, it has been documented that intraoral infusion of milk and injection of the intestinal peptide cholecystokinin (CCK) result in an attenuation in ultrasonic vocalizations (USV) emitted by infant rat pups. One of the most effective stimuli in inhibiting ingestio...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.10019
更新日期:2002-03-01 00:00:00
abstract::The present study was designed to investigate cocaine self-administration in adult male and female rats exposed prenatally to morphine. Pregnant dams were injected two times a day with either saline, analgesic doses of morphine or no drug at all (controls) on gestation Days 11-18. One day after birth, litters were cro...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20240
更新日期:2007-07-01 00:00:00
abstract::In ovo, late-stage chick embryos repetitively step spontaneously, a locomotor-related behavior also identified as repetitive limb movement (RLM). During RLMs, there is a flexor bias in recruitment and drive of leg muscle activity. The flexor biased activity occurs as embryos assume an extremely flexed posture in a spa...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21594
更新日期:2018-03-01 00:00:00
abstract::The effects of short-term bilateral naris occlusion (inducing olfactory deprivation) on mother-pup interactions, suckling behavior and hormonal status during post-natal development in Wistar rats were studied. Bilateral naris occlusion was performed on 8-day-old rat pups and its effects were evaluated at Day 9 and at ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20523
更新日期:2011-04-01 00:00:00
abstract::In a first experiment, vaginally delivered Day 21 and Caesarean delivered Day 20 and Day 21 rat pups were isolated in the presence of various odorants or no odorant for 1 hr immediately following birth. For Day 20 pups, exposure to novel mint odor resulted in higher mortality during isolation than did exposure to the ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420200406
更新日期:1987-07-01 00:00:00
abstract::The learning of multiple choice discrimination tasks of 3-, 4-, 5-, and 6-year-old children was compared using the components of learning of cue significance and response regulation. No significant differences between age groups were found in the occurrence of cue significance learning, although the younger children's...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420180304
更新日期:1985-05-01 00:00:00
abstract::Using techniques developed by Hall (1975) and modified by Diaz (1991), we maintained rat pups in total social isolation from the time they were 2 or 3 days of age until they were 42 days old. We found that rat pups reared in social isolation exhibited susceptibility to social enhancement of food preference indistingui...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420270202
更新日期:1994-03-01 00:00:00
abstract::The presence of context-specific communication sounds, structurally different call types related to particular situations and potentially expressing distinct emotions of the caller, were not systematically studied in infants of strepsirrhine primates. We exposed suckling's of gray mouse lemurs (Microcebus murinus) in ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20234
更新日期:2007-11-01 00:00:00
abstract::This study evaluated the immunological, hormonal, and behavioral responses of juvenile squirrel monkeys to repeated social separations of varying length. Following a 3-hr separation, lymphocyte responses to stimulation with the mitogen concanavalin A (Con A) declined significantly, and these alterations were sustained...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420240303
更新日期:1991-04-01 00:00:00
abstract::Schizophrenia is a complex neuropsychiatric disorder characterized by hallucinations, delusions, anhedonia, flat affect and cognitive impairments. The aim of this study was to propose a prenatal treatment with ketamine, a psychedelic drug that acts as a non-competitive inhibitor of glutamate NMDA receptors, as a neuro...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21586
更新日期:2018-01-01 00:00:00
abstract::Data from a variety of sources, including a number of tasks and dependent measures, suggests that a systematic inverse relationship exists between age and the amount of variability observed on simple measures of learning. Implications for general theoretical perspectives concerning ontogenetic differences in stimulus ...
journal_title:Developmental psychobiology
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1098-2302(199604)29:3<219::AID-DEV3>
更新日期:1996-04-01 00:00:00
abstract::Handled rabbit pups react with decreased fear to a human at weaning. We hypothesized that pups learn species-specific features of their handler. Experiment 1 showed that handled animals' reactions were similar to both a human and their mother. Experiment 2 showed that pups reacted similarly to their mother and other a...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.1028
更新日期:2001-07-01 00:00:00
abstract::Despite evidence that acute stress impairs attention in adults, there has been minimal research in children. Here, the effects of acute stress on Go/No-go performance were examined in young children (M age = 5.41 years). Given the critical role of the parent-child relationship to children's self-regulatory development...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21915
更新日期:2020-05-01 00:00:00
abstract::Autonomic reactivity was studied in individuals with fragile X syndrome (FXS), a genetic disorder partially characterized by abnormal social behavior. Relative to age-matched controls, the FXS group had faster baseline heart rate and lower amplitude respiratory sinus arrhythmia (RSA). In contrast to the typically deve...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20551
更新日期:2011-12-01 00:00:00
abstract::Animal personality has been extensively studied from a functional and evolutionary point of view. Less attention has been paid to the development of personality, its phenotypic plasticity, and the influence of manipulation of early environmental factors. Here we describe the effects of manipulating the sex ratio of th...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20586
更新日期:2011-09-01 00:00:00
abstract::The stability of children's skin conductance level during baselines (SCL-B) and SCL reactivity (SCL-R) were examined longitudinally. During two laboratory sessions (T1 and T2), 2 years apart, children participated in procedures during which they were exposed to two stressors namely exposure to an audiotaped conflict b...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20171
更新日期:2007-03-01 00:00:00
abstract::Feeding mice a diet deficient in n-3 fatty acids for three generations resulted in a 53% decrease in docosahexaenoic acid (DHA, 22:6n-3) in the brain. Maternal pup retrieval and social learning of a food preference are both tasks based on olfactory function. All dams made contact more readily with pups of their own di...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420270705
更新日期:1994-11-01 00:00:00
abstract::The present report examined the effects of undernutrition and handling on shuttle and footshock escape avoidance behavior of female rats. Rats were undernourished by feeding their dams a 7% casein diet from birth until 23 days of life. During this period rats were separated from their dams for 4 to 10 min. On days 23 ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420230206
更新日期:1990-03-01 00:00:00
abstract::Patterns of visual interaction in mother-infant dyadic behavior have been reported for human and nonhuman primates, including age and gender differences among rhesus macaques. Such findings are tested with data from two developmental periods (Weeks 1-8 and 21-36) on Japanese macaque mother-infant visual behavior. Rate...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420170406
更新日期:1984-07-01 00:00:00
abstract::Adult patients with damage centered around the frontal eye fields are severely impaired in the ability to suppress unwanted automatic saccades and in the ability to make volitional eye movements. Over the first few weeks of life most saccades generated by infants appear to be automatic, and are triggered in response t...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420280504
更新日期:1995-07-01 00:00:00
abstract::Contractile activity of the uterus before the onset of labor (uterine contractures) has been described in a number of species and provides a powerful source of repeated stimulation for the fetus throughout much of gestation. To understand how fetal behavior responds to this dynamic aspect of the intrauterine environme...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/(SICI)1098-2302(199612)29:8<667::AID-DEV3>
更新日期:1996-12-01 00:00:00
abstract::Oxytocin (OT) has an organizational effect within the central nervous system and can have long-lasting effects on the expression of social behavior. OT has recently been implicated in modulating the release of serotonin through activation of receptors in the raphe nuclei. Here we test the hypothesis that OT can have a...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.20566
更新日期:2012-01-01 00:00:00
abstract::Adolescence is a time involving a series of changes in the use of appetitive reinforcers like food, as well as neuroendocrine changes like those taking place in the mesolimbic dopamine function. Social isolation from postnatal day 21 to 36 in rats leads to behavioral and neurophysiological alterations such as increase...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21273
更新日期:2015-03-01 00:00:00
abstract::This study investigates the effects of a biologically relevant stressor, crowding, on the development of neurons in the major teleostean brain area, the optic tectum. Adult jewel fish were reared for approximately 4 years under conditions of moderate density (3.3 liter/fish), or under uncrowded control conditions (25 ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420150508
更新日期:1982-09-01 00:00:00
abstract::Eight- and 11- to 12-day-old rat pups were tested in isolation and in the presence of an anesthetized adult under cold conditions. Pups of both ages reduced rates of ultrasonic vocalization (USV) when an adult was placed into the test cage, independent of whether the adult was their dam or an unrelated male. However, ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/(sici)1098-2302(199704)30:3<195::aid-dev2>
更新日期:1997-04-01 00:00:00
abstract:INTRODUCTION:The long allele of the DRD4 gene can confer different behavioral and emotional phenotypes depending upon environmental exposure, although the physiological changes underlying these phenotypes are not fully known. We sought to extend this work by assessing the interaction of the DRD4 gene and exposure to pe...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.21539
更新日期:2017-09-01 00:00:00
abstract::In order to examine the effects of cannabinoids, malnutrition, and their possible interaction upon the developing rat fetus, female Wistar rats were exposed to cannabis smoke, placebo smoke, or no smoke while concurrently consuming 1 of 3 diets differing in protein concentration (8%, 24%, 64%). Both the diet and drug ...
journal_title:Developmental psychobiology
pub_type: 杂志文章
doi:10.1002/dev.420130605
更新日期:1980-11-01 00:00:00