Abstract:
INTRODUCTION:To evaluate the sensitivity of electrophysiologic assessments, we compared F-waves and motor and sensory nerve conduction studies (MNCS and SNCS) in patients with diabetes mellitus (DM). METHODS:We tested median, ulnar, tibial, and fibular nerves in 132 DM patients divided into those with and without clinical evidence of polyneuropathy. RESULTS:Of 64 asymptomatic patients, 2 (3%) had MNCS or SNCS abnormalities, both of whom had F-wave changes, whereas 21 (33%) had only delayed F-waves, for a combined yield of 23 (36%). The corresponding values for 68 symptomatic patients consisted of 43 (63%), 14 (21%), and 57 (84%). In both groups, F-wave latency had a higher (P<0.05) frequency of abnormality than MNCS in all nerves. F-wave study also surpassed SNCS in lower limb nerves. CONCLUSIONS:F-waves of the tibial and fibular nerves are the most sensitive measure to detect subclinical or overt diabetic polyneuropathy. Muscle Nerve 49: 804-808, 2014.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Pan H,Jian F,Lin J,Chen N,Zhang C,Zhang Z,Ding Z,Wang Y,Cui L,Kimura Jdoi
10.1002/mus.24127subject
Has Abstractpub_date
2014-06-01 00:00:00pages
804-8issue
6eissn
0148-639Xissn
1097-4598journal_volume
49pub_type
杂志文章相关文献
MUSCLE & NERVE文献大全abstract::The mdx mouse, an animal model used to study Duchenne muscular dystrophy, has a nonsense mutation in exon 23 of the dystrophin gene which should result in a truncated protein that cannot be correctly localized at the sarcolemma of the muscle fibers. Immunohistochemical staining with antidystrophin antibodies has shown...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199706)20:6<728::aid-mus10
更新日期:1997-06-01 00:00:00
abstract:INTRODUCTION:Thymectomy is required for the treatment of thymoma-associated myasthenia gravis (MG). However, MG may develop only after thymectomy, a condition known as post-thymectomy MG. This study aimed to investigate the risk factors for post-thymectomy MG in patients with thymoma. METHODS:We retrospectively identi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.27169
更新日期:2021-01-12 00:00:00
abstract::Data are scarce relating to the plasticity with strength training of dynamic muscle performance in older humans. Hence, we investigated alterations in the torque-velocity relation with strength training in old age, and their origin. Knee extension and leg-press exercises were performed three times per week for 14 week...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20275
更新日期:2005-03-01 00:00:00
abstract::Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disorder characterized by autoantibodies against presynaptic voltage-gated calcium channels that impair neuromuscular transmission. Malignancies, especially small cell lung cancer (SCLC), have been associated with LEMS and account for approximately 60% of cases...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24122
更新日期:2014-03-01 00:00:00
abstract::Disappointing functional recovery following peripheral nerve repair can be improved by neurotrophic growth factors. Leukemia inhibitory factor (LIF) is unique in that it has independent neurotrophic and myotrophic actions. The aim of this study was to explain this finding by establishing the existence of anterograde a...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199901)22:1<78::aid-mus12>
更新日期:1999-01-01 00:00:00
abstract:INTRODUCTION:In this study we present a reproducible technique to assess motor recovery after nerve injury via neuromuscular junction (NMJ) immunostaining and electrodiagnostic testing. METHODS:Wild-type mice underwent sciatic nerve transection with repair. Hindlimb muscles were collected for microscopy up to 30 weeks...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26654
更新日期:2019-11-01 00:00:00
abstract:INTRODUCTION:Similar to magnetic resonance imaging (MRI), electrical impedance myography (EIM) is dependent on the presence and location of water in muscle to assess neuromuscular diseases. We compared the 2 technologies in mdx mice to better understand their relationship. METHODS:EIM and MRI, using T2 relaxation and ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24573
更新日期:2015-10-01 00:00:00
abstract:INTRODUCTION:Anecdotal reports from families and care providers suggest a wide variation in services received by individuals with Duchenne/Becker muscular dystrophy (DBMD). METHODS:We documented the type and frequency of health services received by individuals with DBMD using the Muscular Dystrophy Surveillance Tracki...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24727
更新日期:2016-02-01 00:00:00
abstract::Obese individuals have slowed conduction in the median nerve across the wrist, but the mechanism for this is not established. This case-control study of 27 obese subjects and 16 thin subjects was designed to test the hypothesis that obese individuals have higher carpal canal pressures and more median nerve swelling th...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20125
更新日期:2004-10-01 00:00:00
abstract:INTRODUCTION:Sarcopenia likely comprises muscle fiber denervation and re-innervation, resulting in clustering of muscle fibers of the same type (classified by myosin heavy chain isoform composition). Development of methodology to quantitatively evaluate clustering of muscle fibers according to fiber type is necessary. ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24641
更新日期:2015-07-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to describe the therapeutic effects of immunomodulatory therapy in 3 patients with childhood autoimmune necrotizing myopathy with anti-signal recognition particle antibodies (SRP-ANM). METHODS:Before treatment, data on clinical features, muscle pathology, and thigh MRIs were obta...
journal_title:Muscle & nerve
pub_type:
doi:10.1002/mus.25575
更新日期:2017-12-01 00:00:00
abstract:INTRODUCTION:Factors determining response to intravenous immunoglobulin (IVIg) and plasmapheresis in myasthenia gravis (MG) have not been evaluated systematically. METHODS:This study included patients treated with IVIg (n = 63) or plasmapheresis (n = 42) from two trials evaluating IVIg vs. placebo or plasmapheresis in...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23236
更新日期:2012-05-01 00:00:00
abstract::Calpain 3 (C3) is the only muscle-specific member of the calcium-dependent protease family. Although neither its physiological function nor its in vivo substrates are known, C3 must be an important protein for normal muscle function as mutations in the C3 gene result in limb-girdle muscular dystrophy type 2A. Previous...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10465
更新日期:2003-10-01 00:00:00
abstract::Intravenous immunoglobulin (IVIg) is a useful tool in the treatment of a variety of neuromuscular disorders. Though IVIg therapy is generally safe, hemolytic anemia is a potentially serious complication that is often overlooked, and is currently not listed in product inserts. We analyzed 45 patients who received IVIg ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199709)20:9<1142::aid-mus8
更新日期:1997-09-01 00:00:00
abstract::The purpose of this study was to evaluate the effects of spinal cord injury (SCI) and functional electrical stimulation (FES) of paralyzed muscles on type IV collagen content and proteins involving its degradation, which is initiated by matrix metalloproteinase (MMP)-2 and -9 and regulated by their tissue inhibitors (...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(200004)23:4<580::aid-mus18
更新日期:2000-04-01 00:00:00
abstract:INTRODUCTION:Livedoid vasculopathy is a rare dermatological condition characterized by painful ulceration, atrophic scarring, and persistent livedo reticularis. The pathogenesis is unclear. METHODS:We report a patient with biopsy-proven livedoid vasculopathy who developed a progressive sensory ganglionopathy with prof...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24452
更新日期:2015-02-01 00:00:00
abstract::n-Hexane neuropathy was studied in 20 workers exposed for prolonged periods to this solvent, and with urinary 2,5-hexanedione concentrations exceeding the biological exposure index recommended by the American Conference of Governmental Industrial Hygienists (5 mg/L) with a mean of 11.02 mg/L (range 5.3-24.2 mg/L). Alt...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880170904
更新日期:1994-09-01 00:00:00
abstract::To enable the quantitative assessment of peripheral nerve structure and function, we determined the normal values for sural nerve hydration structure as measured by magnetic resonance proton imaging, and for neurological function with scores for neuropathic symptoms, signs, and nerve conduction properties. Normal huma...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880160311
更新日期:1993-03-01 00:00:00
abstract::Electromyographic examination of the deeper external anal sphincter (EAS) muscle is far more uncomfortable than of the subcutaneous muscle, so we tested the need for its examination. We compared the findings in 85 paired examinations of ipsilateral subcutaneous and deeper EAS muscles in 67 patients with a cauda equina...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.10417
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:We aimed to describe the electrophysiological progression rate of chronic idiopathic axonal polyneuropathy (CIAP) and look into the potential role of human leukocyte antigen (HLA) genetic susceptibility in its development. METHODS:We recruited 57 patients with CIAP (mean age at diagnosis 67, mean follow-up ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.27164
更新日期:2021-01-13 00:00:00
abstract:INTRODUCTION:Neuralgic amyotrophy (NA) often imposes diagnostic problems. Recently, MRI and high-resolution ultrasound (HRUS) have proven useful in diagnosing peripheral nerve disorders. METHODS:We performed a chart and imaging review of patients who were examined using neuroimaging and who were referred because of cl...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25147
更新日期:2016-12-01 00:00:00
abstract::Immunocytochemical analysis of muscle specimens from 5 patients with acute quadriplegic myopathy indictes that depletion of either fast or slow myosin occurs in this disorder. The initial lesion consists of focal myosin loss in nonatrophic fibers. Other structural proteins (actin, titin, nebulin) are spared or affecte...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(SICI)1097-4598(199703)20:3<316::AID-MUS8>
更新日期:1997-03-01 00:00:00
abstract::Clinicopathologic findings from two golden retriever dogs with an inherited, progressive, degenerative muscle disease that were studied until 27 and 40 months of age are described. Initial clinical signs included stilted gait and simultaneous advancement of their pelvic limbs. Further gait restriction and muscle hyper...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880111008
更新日期:1988-10-01 00:00:00
abstract:INTRODUCTION:Changes in subsynovial connective tissue (SSCT) in carpal tunnel syndrome (CTS) patients may result in altered dynamics; consequently, quantification of these dynamics might support objective diagnosis of CTS. METHODS:We measured and compared longitudinal excursion of the flexor digitorum superficialis an...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23246
更新日期:2012-05-01 00:00:00
abstract::The loss of contractile protein in Duchenne muscular dystrophy could result from low rates of synthesis, abnormally high rates of protein degradation, or a combination of both. We measured overall protein degradation rates in cultured human muscle cells obtained at biopsy from patients with Duchenne dystrophy or vario...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880080312
更新日期:1985-03-01 00:00:00
abstract:INTRODUCTION:We evaluated diagnostic value of sensory tests during recovery from iatrogenic sensory neuropathy using intraoperatively verified nerve injury with subjective symptoms as gold standard. METHODS:Inferior alveolar nerves were monitored neurophysiologically throughout mandibular osteotomy in 19 patients. Sen...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26400
更新日期:2019-03-01 00:00:00
abstract::Nerve conduction studies (NCS) may be deferred because of a perceived risk of cardiac arrhythmia in the presence of same-limb peripheral intravenous lines. Patients with implanted pacemakers or defibrillators provide a model in whom this risk can be assessed. Twenty patients, seven with pacemakers and 13 with defibril...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21714
更新日期:2010-08-01 00:00:00
abstract::Local cooling of the muscle resulted in significant increases in M wave surface areas in patients with ALS, myasthenia gravis, the Lambert-Eaton myasthenic syndrome, and also in controls. The most striking increases were seen in patients with early ALS who had minimal lower motor neuron involvement and/or little defec...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880130709
更新日期:1990-07-01 00:00:00
abstract::Inhibitory reflex responses to electrical stimulation of the mental nerve were studied in recordings from single motor units (SMU) in the human masseter muscle. A new analytical technique for spike train data was used. Electrical stimuli were delivered to the mental nerve when the SMU fired with two consecutive inter-...
journal_title:Muscle & nerve
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-4598(200002)23:2<259::aid-mus18
更新日期:2000-02-01 00:00:00
abstract::Skeletal muscle cells are hypertrophied by mechanical stresses, but the underlying molecular mechanisms are not fully understood. Two signaling pathways, phosphatidylinositol 3-kinase (PI3K)/Akt to target of rapamycin (TOR) and extracellular signal-regulated kinase kinase (MEK) to extracellular signal-regulated kinase...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21473
更新日期:2010-01-01 00:00:00