M wave changes with temperature in amyotrophic lateral sclerosis and disorders of neuromuscular transmission.

abstract：:Electrodiagnostic evaluation of patients with suspected polyneuropathy is useful for detecting and documenting peripheral abnormalities, identifying the predominant pathophysiology, and determining the prognosis for certain disorders. The electrodiagnostic classification of polyneuropathy is associated with morphologi...

journal_title：Muscle & nerve

authors： Donofrio PD,Albers JW

更新日期：1990-10-01 00:00:00

abstract：:To investigate the role of the thymus in the pathogenesis of myasthenia gravis (MG), immunohistochemical expression of CD44, CD45R0, B7-1, and IL-2 was studied in: (1) hyperplastic thymuses of patients with MG whose symptoms markedly improved after thymectomy, (2) remnant thymuses of patients with MG whose symptoms di...

journal_title：Muscle & nerve

authors： Utsugisawa K,Nagane Y,Tohgi H

更新日期：2000-04-01 00:00:00

abstract：:The loss of muscle strength with aging appears to be greater in the lower than upper limbs, but strength and its neural control have never been compared in the same population of individuals in both upper and lower limbs. The aim of this study was to investigate differences between eight young (20-31 years) and eight ...

journal_title：Muscle & nerve

authors： Bazzucchi I,Felici F,Macaluso A,De Vito G

更新日期：2004-11-01 00:00:00

abstract：INTRODUCTION:Muscle growth and regeneration are processes closely associated with proliferation, differentiation, and apoptosis of muscle cells. Death-associated protein 1 (DAP1) has been identified as a negative regulator of autophagy. Little is known about the function of DAP1 in the regulation of myogenesis and sate...

journal_title：Muscle & nerve

authors： Shin J,McFarland DC,Strasburg GM,Velleman SG

更新日期：2013-11-01 00:00:00

abstract：INTRODUCTION:We report preliminary findings of nerve ultrasound in patients with cerebellar ataxia neuropathy vestibular areflexia syndrome (CANVAS) who have sensory impairment due to dorsal root ganglionopathy. METHODS:The ultrasound cross-sectional area (CSA) of median and ulnar nerves of 7 CANVAS patients was compa...

journal_title：Muscle & nerve

authors： Pelosi L,Leadbetter R,Mulroy E,Chancellor AM,Mossman S,Roxburgh R

更新日期：2017-07-01 00:00:00

abstract：:Our experience and review of the literature reveal that Sjogren's syndrome (SS) is an important, poorly recognized cause of peripheral neuropathy. Several forms of peripheral nerve dysfunction occur in SS including trigeminal sensory neuropathy, mononeuropathy multiplex, distal sensory neuropathy, distal sensorimotor ...

journal_title：Muscle & nerve

authors： Kaplan JG,Rosenberg R,Reinitz E,Buchbinder S,Schaumburg HH

更新日期：1990-07-01 00:00:00

abstract：INTRODUCTION:The objective of this study was to identify the pattern of neurological deficits and document electrophysiological changes in women with macromastia. METHODS:Patients with macromastia and neurological complaints underwent clinical evaluation and electrodiagnostic (EDx) studies of the upper limbs. RESULTS...

journal_title：Muscle & nerve

authors： Ansell JR,Buchholz MC

更新日期：2013-02-01 00:00:00

abstract：INTRODUCTION:The molecular mechanism of immune-mediated necrotizing myopathy (IMNM) remains unknown. Autophagy impairment, described in autoimmune diseases, is a key process in myofiber protein degradation flux and muscle integrity and has not been studied in IMNM. METHODS:Muscle biopsies from patients with IMNM (n = ...

journal_title：Muscle & nerve

authors： Girolamo F,Lia A,Annese T,Giannini M,Amati A,D'Abbicco D,Tampoia M,Virgintino D,Ribatti D,Serlenga L,Iannone F,Trojano M

更新日期：2019-09-01 00:00:00

abstract：:Ten adult myotonic dystrophy patients underwent measurements of lung function, maximal dynamic and static ventilatory efforts, and respiratory muscle electromyography (EMG). EMG studies were performed during spontaneous breathing or when subjects breathed through high inspiratory or expiratory resistive loads. Present...

journal_title：Muscle & nerve

authors： Jammes Y,Pouget J,Grimaud C,Serratrice G

更新日期：1985-09-01 00:00:00

abstract：:The clinical effect of carbamazepine (CBZ) on neuromuscular transmission is described in two children who presented in coma with diffuse hypotonia and areflexia following CBZ overdose. Repetitive nerve stimulation (RNS) showed a decremental response only at high-frequency stimulation. With supportive care, the patient...

journal_title：Muscle & nerve

authors： Zaidat OO,Kaminski HJ,Berenson F,Katirji B

更新日期：1999-09-01 00:00:00

abstract：:This longitudinal study of 194 patients with sporadic ALS demonstrated that it is possible for physicians to predict the approximate survival time for an individual ALS patient given: (1) the age of the patient, (2) the duration of his weakness and (3) an estimate of his clinical disability (ALS Score). This informati...

journal_title：Muscle & nerve

authors： Jablecki CK,Berry C,Leach J

更新日期：1989-10-01 00:00:00

abstract：INTRODUCTION:Spinal and bulbar muscular atrophy (SBMA) and amyotrophic lateral sclerosis (ALS) are motor neuron diseases. Sensory impairment is sometimes observed, and electrophysiological involvement has been described in the sensory nerves of SBMA patients. We hypothesized that a sensory nerve conduction study (NCS) ...

journal_title：Muscle & nerve

authors： Hama T,Hirayama M,Hara T,Nakamura T,Atsuta N,Banno H,Suzuki K,Katsuno M,Tanaka F,Sobue G

更新日期：2012-02-01 00:00:00

abstract：:The reliability of motor unit number estimation (MUNE) for assessment of the long-term course of ALS is dependent on the reproducibility of the technique. We report our results with the statistical method of MUNE on the ulnar nerve/hypothenar muscle in 16 ALS patients who were studied on 52 occasions. On each occasion...

journal_title：Muscle & nerve

authors： Olney RK,Yuen EC,Engstrom JW

更新日期：2000-02-01 00:00:00

abstract：:Human normal (RCMH) and Duchenne muscular dystrophy (RCDMD) cell lines, as well as newly developed normal and dystrophic murine cell lines, were used for the study of both changes in inositol 1,4,5-trisphosphate (IP3) mass and IP3 binding to receptors. Basal levels of IP3 were increased two- to threefold in dystrophic...

journal_title：Muscle & nerve

authors： Liberona JL,Powell JA,Shenoi S,Petherbridge L,Caviedes R,Jaimovich E

更新日期：1998-07-01 00:00:00

abstract：INTRODUCTION:Weakness in patients with chronic inflammatory demyelinating polyneuropathy (CIDP) may be caused by decreases in muscle quantity and quality, but this has not been explored. METHODS:Twelve patients with CIDP (mean age 61 years) and 10 age-matched (mean age 59 years) control subjects were assessed for ankl...

journal_title：Muscle & nerve

authors： Gilmore KJ,Doherty TJ,Kimpinski K,Rice CL

更新日期：2018-09-01 00:00:00

abstract：:Chronic and acute administration of epinephrine or related sympathomimetic agents are typically prescribed for the treatment of clinical disorders such as hypotension, anaphylactic and allergic reactions, and bronchial asthma. In addition to its effects on these infirmaties and on carbohydrate metabolism, epinephrine ...

journal_title：Muscle & nerve

authors： Williams JH,Barnes WS

更新日期：1989-12-01 00:00:00

abstract：:We applied the singular value decomposition (SVD) method to study single motor unit firing patterns. Two projects were carried out: (1) a computer simulation study to confirm the meanings of two SVD parameters, the eigenvalue corresponding to the positive-slope eigenvector (PEV) and that corresponding to the negative-...

journal_title：Muscle & nerve

authors： Sun TY,Chen JJ,Lin TS

更新日期：2000-07-01 00:00:00

abstract：:Technical and instrumentation factors play an important role in obtaining reliable information during electrodiagnostic studies. With contemporary electrodiagnostic equipment, neurophysiologic potentials are detected using a variety of electrodes and undergo differential amplification, filtering, conversion to digital...

journal_title：Muscle & nerve

authors： Gitter AJ,Stolov WC

更新日期：1995-08-01 00:00:00

abstract：:Small-fiber neuropathy is a common disorder. It is often "idiopathic" and typically presents with painful feet in patients over the age of 60. Autoimmune mechanisms are often suspected, but rarely identified. Known causes of small-fiber neuropathy include diabetes mellitus, amyloidosis, toxins, and inherited sensory a...

journal_title：Muscle & nerve

authors： Lacomis D

更新日期：2002-08-01 00:00:00

abstract：:Morphological changes of the subneural apparatus (SNA) during denervation and reinnervation are demonstrated using the hamster peroneus longus muscle. One week after nerve section, synaptic grooves (SGs) were more shallow, with lowered sarcoplasmic ridges. After 4 weeks, the whole SNA area was elevated above the sarco...

journal_title：Muscle & nerve

authors： Matsuda Y,Oki S,Kitaoka K,Nagano Y,Nojima M,Desaki J

更新日期：1988-12-01 00:00:00

abstract：:Task-dependent differences in the facilitation of motor evoked potentials (MEPs) following cortex stimulation were studied in a proximal (deltoid) and a distal muscle (abductor digiti minimi; ADM) in 23 healthy subjects during both dynamic and steady contractions of the target muscle under isometric and under nonisome...

journal_title：Muscle & nerve

authors： Arányi Z,Mathis J,Hess CW,Rösler KM

更新日期：1998-10-01 00:00:00

abstract：:The findings in two cases of congenital myasthenia investigated by intercostal muscle biopsy are presented. The first case, a 16-year-old boy, showed reduced miniature endplate potential amplitude and normal 125I-alpha-bungarotoxin binding to postsynaptic acetylcholine receptors. Muscle biopsy and endplate ultrastruct...

journal_title：Muscle & nerve

authors： Lecky BR,Morgan-Hughes JA,Murray NM,Landon DN,Wray D,Prior C

更新日期：1986-03-01 00:00:00

abstract：:In order to further characterize and provide a possible mechanism for the asymmetrical involvement of forearm muscles in inclusion body myositis (IBM), we measured isometric hand and pinch grip strength, and forearm muscle girth on 15 IBM patients. Forearm muscle strength and girth were significantly greater on the do...

journal_title：Muscle & nerve

authors： Felice KJ,Relva GM,Conway SR

更新日期：1998-05-01 00:00:00

abstract：:Biochemical, morphologic, and biophysical studies support the concept that the red blood cell (RBC) membrane is altered in both myotonic muscular dystrophy (MyD) and Duchenne muscular dystrophy (DMD). These studies have not identified a primary metabolic defect that would explain the various alterations of membrane pr...

journal_title：Muscle & nerve

authors： Plishker GA,Appel SH

更新日期：1980-01-01 00:00:00

abstract：INTRODUCTION:Nemaline myopathy is a rare disorder characterized by skeletal muscle weakness of varying severity and onset, with the presence of nemaline rods on muscle biopsy. Congenital nemaline body myopathy due to mutations in TNNT1 has hitherto only been described as a result of a single founder mutation in patient...

journal_title：Muscle & nerve

authors： Abdulhaq UN,Daana M,Dor T,Fellig Y,Eylon S,Schuelke M,Shaag A,Elpeleg O,Edvardson S

更新日期：2016-04-01 00:00:00

abstract：INTRODUCTION:Mutations in gap junction protein beta 1 (GJB1) on the X chromosome represent one of the most common causes of hereditary neuropathy. We assessed manifestations associated with a rare 3' untranslated region mutation (UTR) of GJB1 in a large family with X-linked Charcot-Marie-Tooth disease (CMTX). METHODS:...

journal_title：Muscle & nerve

authors： Chen DH,Ma M,Scavina M,Blue E,Wolff J,Karna P,Dorschner MO,Raskind WH,Bird TD

更新日期：2018-05-01 00:00:00

abstract：INTRODUCTION:Transitioning from adolescence to adulthood can be problematic for individuals with rare disabilities such as muscular dystrophy (MD). METHODS:We identified a cohort of 220 individuals with MD and 440 matched comparison individuals and measured emergency room (ER) and inpatient (IP) encounters for the yea...

journal_title：Muscle & nerve

authors： Mann JR,Royer JA,Mcdermott S,Hardin JW,Ozturk O,Street N

更新日期：2015-11-01 00:00:00

abstract：:We examined and compared a mechanosensitive human sural neuroma and a contralateral sural nerve collected simultaneously from a patient involved in a diabetic neuropathy research protocol. Using indirect immunofluorescence staining. we identified a striking difference in the content within axons of two neuropeptides, ...

journal_title：Muscle & nerve

authors： Zochodne DW,Theriault M,Sharkey KA,Cheng C,Sutherland G

更新日期：1997-07-01 00:00:00

abstract：:The voluntary discharge properties and axonal conduction velocity of single motor units were studied in patients with neuromuscular diseases with retained differentiation of the muscle fibers into type 1 and type 2, and in patients with late-onset hereditary distal myopathy in which muscle fibers have only intermediat...

journal_title：Muscle & nerve

authors： Borg J,Grimby L,Hannerz J

更新日期：1979-11-01 00:00:00

abstract：INTRODUCTION:Eosinophilic fasciitis (EF) is a rare disorder that can present with muscle symptoms that mimic other neuromuscular diseases. METHODS:We report the case of a 43-year-old woman with chronic muscle aches, tightness, and stiffness with hypertrophied, well-defined muscles despite physical inactivity, and thic...

journal_title：Muscle & nerve

authors： Whitlock JB,Dimberg EL,Selcen D,Rubin DI

更新日期：2017-09-01 00:00:00