Abstract：
:Using absorption spectroscopy we have found that metallothionein I at concentrations as low as 1 microM reduces ferricytochrome c. This reduction is more potent than that of another abundant intracellular thiol, glutathione. Also, oxidation of ferricytochrome c which had been reduced by metallothionein I occurs more slowly than when the reductant was glutathione. Over a pH range of 6 through 9 there is no variation in the initial rate of metallothionein I reduction of ferricytochrome c. These data demonstrate a potent interaction between metallothionein I and ferricytochrome c.
journal_name
Life Scijournal_title
Life sciencesauthors
Simpkins C,Eudaric P,Torrence C,Yang Zdoi
10.1016/0024-3205(93)90019-ysubject
Has Abstractpub_date
1993-01-01 00:00:00pages
1975-80issue
26eissn
0024-3205issn
1879-0631pii
0024-3205(93)90019-Yjournal_volume
53pub_type
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