Development of the human brain: in vivo quantification of metabolite and water content with proton magnetic resonance spectroscopy.

abstract：:Reaching the full potential of magnetic resonance imaging (MRI)-positron emission tomography (PET) dual modality systems requires new methodologies in quantitative image analyses. In this study, methods are proposed to convert an arterial input function (AIF) derived from gadolinium-diethylenetriaminepentaacetic acid ...

journal_title：Magnetic resonance in medicine

authors： Poulin E,Lebel R,Croteau E,Blanchette M,Tremblay L,Lecomte R,Bentourkia M,Lepage M

更新日期：2013-03-01 00:00:00

abstract：:As the static magnetic field strength used in human magnetic resonance imaging increases, the wavelength of the corresponding radiofrequency field becomes comparable to the dimensions of the coil and volume of interest. The dielectric resonance effects that arise in this full wavelength regime may be partially compens...

journal_title：Magnetic resonance in medicine

authors： Pinkerton RG,Barberi EA,Menon RS

更新日期：2005-08-01 00:00:00

abstract：:Problems with in vivo proton spectroscopy include strong water and lipid signals, and the very complicated structures of the spectra. Multiple-quantum experiments can be designed to overcome these difficulties. Using a volume selective refocusing technique, one can demonstrate how multiple-quantum experiments can be p...

journal_title：Magnetic resonance in medicine

authors： McKinnon GC,Bosiger P

更新日期：1988-03-01 00:00:00

abstract：:Imaging of stable paramagnetic spin probes in phantom objects and in vivo was evaluated using a RF time domain EPR spectrometer/imager operating at 300 MHz. Projections were collected using static magnetic field gradients and images were reconstructed using filtered back-projection techniques. Results from phantom obj...

journal_title：Magnetic resonance in medicine

authors： Afeworki M,van Dam GM,Devasahayam N,Murugesan R,Cook J,Coffin D,Larsen JH,Mitchell JB,Subramanian S,Krishna MC

更新日期：2000-03-01 00:00:00

abstract：:Diffusion tensor imaging has been used in a number of spinal cord studies, but severe distortions caused by susceptibility induced field inhomogeneities limit its applicability to investigate small volumes within acceptable acquisition times. A way to evaluate image distortions is to map the point spread function of t...

journal_title：Magnetic resonance in medicine

authors： Lundell H,Barthelemy D,Biering-Sørensen F,Cohen-Adad J,Nielsen JB,Dyrby TB

更新日期：2013-01-01 00:00:00

abstract：:Accurate and reproducible MRI R2 * relaxometry for tissue iron quantification is important in managing transfusion-dependent patients. MRI data are often acquired using array coils and reconstructed by the root-sum-square algorithm, and as such, measured signals follow the noncentral chi distribution. In this study, t...

journal_title：Magnetic resonance in medicine

authors： Feng Y,He T,Gatehouse PD,Li X,Harith Alam M,Pennell DJ,Chen W,Firmin DN

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:To develop an accelerated, robust, and accurate diffusion MRI acquisition and reconstruction technique for submillimeter whole human brain in vivo scan on a clinical scanner. METHODS:We extend the ultra-high resolution diffusion MRI acquisition technique, gSlider, by allowing undersampling in q-space and radio...

journal_title：Magnetic resonance in medicine

authors： Ramos-Llordén G,Ning L,Liao C,Mukhometzianov R,Michailovich O,Setsompop K,Rathi Y

更新日期：2020-10-01 00:00:00

abstract：:For sodium imaging of the human brain, Gibbs' ringing can degrade image appearance and confound image analysis; k-space filtering is generally required. In this work, the signal to noise ratio (SNR) advantage of sampling density weighted apodization (SDWA) over uniform k-space sampling with postacquisition filtering a...

journal_title：Magnetic resonance in medicine

authors： Stobbe R,Beaulieu C

更新日期：2008-10-01 00:00:00

abstract：PURPOSE:Segmentation of cardiac cine MRI data is routinely used for the volumetric analysis of cardiac function. Conventionally, 2D contours are drawn on short-axis (SAX) image stacks with relatively thick slices (typically 8 mm). Here, an acquisition/reconstruction strategy is used for obtaining isotropic 3D cine data...

journal_title：Magnetic resonance in medicine

authors： Odille F,Bustin A,Liu S,Chen B,Vuissoz PA,Felblinger J,Bonnemains L

更新日期：2018-05-01 00:00:00

abstract：:The concentration of oxygen within cells is important in many physiological and pathological processes, but such oxygen-dependent phenomena are generally studied as a function of the concentration of extracellular oxygen, due to a lack of suitable methods. Electron parmamagnetic resonance (EPR) oximetric techniques of...

journal_title：Magnetic resonance in medicine

authors： Glockner JF,Norby SW,Swartz HM

更新日期：1993-01-01 00:00:00

abstract：:An intermolecular double-quantum coherence (iDQC) imaging technique was used to study auditory activation in the human brain at 1.5T with a dual temporal lobe surface phased array coil and a quadrature head coil. Preliminary results demonstrate that it is feasible to obtain auditory activation maps using iDQC imaging ...

journal_title：Magnetic resonance in medicine

authors： Zhong J,Kwok E,Chen Z

更新日期：2001-03-01 00:00:00

abstract：:The intra-individual and inter-individual variations of the global N-acetylaspartate (NAA) concentration were measured in a cohort of five 42+/-5 year-old normal females. The total NAA signal from the whole head was obtained with non-localized non-echo proton spectroscopy (1H-MRS) and converted into absolute mole amou...

journal_title：Magnetic resonance in medicine

authors： Gonen O,Viswanathan AK,Catalaa I,Babb J,Udupa J,Grossman RI

更新日期：1998-11-01 00:00:00

abstract：:In an effort to develop MRI methods for the evaluation of tumor angiogenesis (new blood vessel formation), MRI-derived cerebral blood volume (CBV) information has been compared to histologic measures of microvessel density (MVD). Although MVD is a standard marker of angiogenesis, it is not a direct correlate of the vo...

journal_title：Magnetic resonance in medicine

authors： Pathak AP,Schmainda KM,Ward BD,Linderman JR,Rebro KJ,Greene AS

更新日期：2001-10-01 00:00:00

abstract：:Brain water proton (1H2O) longitudinal relaxation time constants (T1) were obtained from three healthy individuals at magnetic field strengths (B0) of 0.2 Tesla (T), 1.0T, 1.5T, 4.0T, and 7.0T. A 5-mm midventricular axial slice was sampled using a modified Look-Locker technique with 1.5 mm in-plane resolution, and 32 ...

journal_title：Magnetic resonance in medicine

authors： Rooney WD,Johnson G,Li X,Cohen ER,Kim SG,Ugurbil K,Springer CS Jr

更新日期：2007-02-01 00:00:00

abstract：:Diffusion tensor imaging enables in vivo investigation of tissue cytoarchitecture through parameter contrasts sensitive to water diffusion barriers at the micrometer level. Parameters are derived through an estimation process that is susceptible to noise and artifacts. Estimated parameters (e.g., fractional anisotropy...

journal_title：Magnetic resonance in medicine

authors： Lauzon CB,Crainiceanu C,Caffo BC,Landman BA

更新日期：2013-03-01 00:00:00

abstract：:Parallel excitation is being studied intensively for applications in MR imaging and in particular for selecting arbitrary shapes as regions of interest. In this work, parallel excitation was applied to arbitrarily shaped voxel selection in spectroscopy and investigated for different excitation k-space trajectories (ra...

journal_title：Magnetic resonance in medicine

authors： Snyder J,Haas M,Hennig J,Zaitsev M

更新日期：2012-02-01 00:00:00

abstract：PURPOSE:As prescribed and reliable geometrical entities, phantoms have served as indispensable validation tools in a variety of MR-related topics. Though a number of phantoms have been conceived, certain applications may warrant highly customized geometries. The purpose of this study was to demonstrate the expediency o...

journal_title：Magnetic resonance in medicine

authors： Kasten JA,Vetterli T,Lazeyras F,Van De Ville D

更新日期：2016-01-01 00:00:00

abstract：:Magnetoferritin nanoparticles have been developed as high-relaxivity, functional contrast agents for MRI. Several previous techniques have relied on unloading native ferritin and re-incorporation of iron into the core, often resulting in a polydisperse sample. Here, a simplified technique is developed using commercial...

journal_title：Magnetic resonance in medicine

authors： Jordan VC,Caplan MR,Bennett KM

更新日期：2010-11-01 00:00:00

abstract：:Each k-space segment in multishot diffusion-weighted MRI is affected by a different spatially varying phase which is caused by unavoidable motions and amplified by the diffusion-encoding gradients. A proper image reconstruction therefore requires phase maps for each segment. Such maps are commonly derived from two-dim...

journal_title：Magnetic resonance in medicine

authors： Uecker M,Karaus A,Frahm J

更新日期：2009-11-01 00:00:00

abstract：:The concept of temporal echo multiplexing is defined and used to develop rapid biphasic spin-echo sequences for imaging the heart. Three imaging sequences, based on four-echo and two-echo multiplexing and rapid single echo (i.e., conventional spin-echo imaging), are compared. Preliminary results indicate that two-echo...

journal_title：Magnetic resonance in medicine

authors： Parker DL,Caputo GR,Frederick PR

更新日期：1989-07-01 00:00:00

abstract：:Fractional anisotropy (FA) and relative anisotropy (RA) are the two most commonly used scalar measures of anisotropy in diffusion tensor (DT) MRI. While a few published studies have shown that FA has superior noise immunity relative to RA, no theoretical basis has been proposed to explain this behavior. In the current...

journal_title：Magnetic resonance in medicine

authors： Hasan KM,Alexander AL,Narayana PA

更新日期：2004-02-01 00:00:00

abstract：:Aim of the study was to determine distribution and depletion patterns of intramyocellular lipids (IMCL) in leg muscles before and after two types of standardized endurance exercise. ¹H-magnetic resonance spectroscopic imaging was performed (1) in the thigh of eight-trained cyclists after exercising on an ergometer for...

journal_title：Magnetic resonance in medicine

authors： Vermathen P,Saillen P,Boss A,Zehnder M,Boesch C

更新日期：2012-11-01 00:00:00

abstract：:Dual labeled liposomes, carrying both paramagnetic and fluorescent lipids, were recently proposed as potent contrast agents for MR molecular imaging. These nanoparticles are coated with poly(ethylene glycol) (PEG) to increase their blood circulation half-life, which should allow extensive accumulation at the targeted ...

journal_title：Magnetic resonance in medicine

authors： van Tilborg GA,Strijkers GJ,Pouget EM,Reutelingsperger CP,Sommerdijk NA,Nicolay K,Mulder WJ

更新日期：2008-12-01 00:00:00

abstract：:A cerebrospinal fluid (CSF)-suppressed flow-attenuated inversion recovery (FLAIR) double-shot diffusion echo-planar imaging (EPI) sequence was developed and used, along with a non-CSF-suppressed version of the sequence, to determine the extent of the contribution of CSF partial-volume averaging to the apparent diffusi...

journal_title：Magnetic resonance in medicine

authors： Falconer JC,Narayana PA

更新日期：1997-01-01 00:00:00

abstract：:We used deuterium magnetic resonance imaging (2H MRI) to visualize water movement in the rabbit eye. Dynamic 2H MRI was obtained every 3.5 min at 2 tesla by FLASH pulse sequence (TR, 300 ms; TE, 10 ms; alpha = 90 degrees) with a slice thickness of 10 mm using a surface coil (4 cm in diameter). After topical administra...

journal_title：Magnetic resonance in medicine

authors： Obata T,Ikehira H,Koga M,Yoshida K,Kimura F,Tateno Y

更新日期：1995-04-01 00:00:00

abstract：:In several applications, MRI is used to monitor the time behavior of the signal in an organ of interest; e.g., signal evolution because of physiological motion, activation, or contrast-agent accumulation. Dynamic applications involve acquiring data in a k-t space, which contains both temporal and spatial information. ...

journal_title：Magnetic resonance in medicine

authors： Madore B,Glover GH,Pelc NJ

更新日期：1999-11-01 00:00:00

abstract：:In in vivo phosphorus magnetic resonance spectroscopy (MRS), spectroscopic imaging (SI) can be used as a flexible localization technique, producing spectra from multiple volumes in a single examination. Presented here are phosphorus SI studies of human organs in which a selective-volume SI reconstruction was used rath...

journal_title：Magnetic resonance in medicine

authors： Twieg DB,Meyerhoff DJ,Hubesch B,Roth K,Sappey-Marinier D,Boska MD,Gober JR,Schaefer S,Weiner MW

更新日期：1989-12-01 00:00:00

abstract：:The fate of the 13C label arising from [U-13C]succinate in rabbit renal proximal convoluted tubular (PCT) cells, incubated with [U-13C]succinate, was investigated by 13C NMR spectroscopy of the perchloric acid extracts of the cell pellets. The 13C label of [U-13C]succinate was predominantly metabolized into glutamate,...

journal_title：Magnetic resonance in medicine

authors： Jans AW,Willem R

更新日期：1990-04-01 00:00:00

abstract：:A new ultrafast MR imaging method is proposed and tested, which enables whole-brain fMRI with a true temporal resolution of 1 sec. The method combines a 3D PRESTO pulse sequence with the concept of sensitivity-encoding with multiple receiver coils (SENSE). The so-called PRESTO-SENSE technique is demonstrated on a set ...

journal_title：Magnetic resonance in medicine

authors： Golay X,Pruessmann KP,Weiger M,Crelier GR,Folkers PJ,Kollias SS,Boesiger P

更新日期：2000-06-01 00:00:00

abstract：:Transmit and receive RF coil arrays have proven to be particularly beneficial for ultra-high-field MR. Transmit coil arrays enable such techniques as B(1) (+) shimming to substantially improve transmit B(1) homogeneity compared to conventional volume coil designs, and receive coil arrays offer enhanced parallel imagin...

journal_title：Magnetic resonance in medicine

authors： Adriany G,Auerbach EJ,Snyder CJ,Gözübüyük A,Moeller S,Ritter J,Van de Moortele PF,Vaughan T,Uğurbil K

更新日期：2010-06-01 00:00:00