Evidence for existence in human tissues of monomers for plastics and rubber manufacture.

abstract：BACKGROUND:Chronic exposure to well water arsenic (As) remains a major rural health challenge in Bangladesh and some other developing countries. Many mitigation programs have been implemented to reduce As exposure, although evaluation studies for these efforts are rare in the literature. OBJECTIVES:In this study we es...

journal_title：Environmental health perspectives

authors： Khan K,Ahmed E,Factor-Litvak P,Liu X,Siddique AB,Wasserman GA,Slavkovich V,Levy D,Mey JL,van Geen A,Graziano JH

更新日期：2015-12-01 00:00:00

abstract：:The association of blood lead (B-Pb) concentration to blood pressure was investigated in men aged 55 to 75 years living in the Rome area, who had no history of exposure to lead in the workplace and who participated between 1989 and 1990 in an epidemiologic survey for coronary heart disease (New Risk Factor Project). O...

journal_title：Environmental health perspectives

authors： Menditto A,Morisi G,Spagnolo A,Menotti A

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Previous literature suggests that higher ambient temperature may play a role in increasing the risk of suicide. However, no multi-country study has explored the shape of the association and the role of moderate and extreme heat across different locations. OBJECTIVES:We examined the short-term temperature-su...

journal_title：Environmental health perspectives

authors： Kim Y,Kim H,Gasparrini A,Armstrong B,Honda Y,Chung Y,Ng CFS,Tobias A,Íñiguez C,Lavigne E,Sera F,Vicedo-Cabrera AM,Ragettli MS,Scovronick N,Acquaotta F,Chen BY,Guo YL,Seposo X,Dang TN,de Sousa Zanotti Stagliorio Coel

更新日期：2019-11-01 00:00:00

abstract：:There is a significant public health concern about the potential effects of occupational exposure to toxic substances on reproductive outcomes. Several toxicants with reported reproductive and developmental effects are still in regular commercial or therapeutic use and thus present potential exposure to workers. Examp...

journal_title：Environmental health perspectives

authors： Lawson CC,Schnorr TM,Daston GP,Grajewski B,Marcus M,McDiarmid M,Murono E,Perreault SD,Schrader SM,Shelby M

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Bisphenol A (BPA) is known to be biologically active in experimental models even at low levels of exposure. However, its impact on endometrial cancer remains unclear. OBJECTIVES:This study aimed to investigate whether lifelong exposure to different doses of BPA induced uterine abnormalities and molecular ch...

journal_title：Environmental health perspectives

authors： Leung YK,Biesiada J,Govindarajah V,Ying J,Kendler A,Medvedovic M,Ho SM

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:"Airwave" is the new communication system currently being rolled out across the United Kingdom for the police and emergency services, based on the Terrestrial Trunked Radio Telecommunications System (TETRA). Some police officers have complained about skin rashes, nausea, headaches, and depression as a conseq...

journal_title：Environmental health perspectives

authors： Wallace D,Eltiti S,Ridgewell A,Garner K,Russo R,Sepulveda F,Walker S,Quinlan T,Dudley S,Maung S,Deeble R,Fox E

更新日期：2010-06-01 00:00:00

abstract：:In 1994 officials from the Ohio Department of Health reported that some residents of Lorain County, Ohio, possibly had been exposed to methyl parathion (MP), a highly toxic restricted-use pesticide. The U.S. Centers for Disease Control and Prevention (CDC) assisted in the investigation by providing epidemiologic and l...

journal_title：Environmental health perspectives

authors： Hill RH Jr,Head S,Barr DB,Rubin C,Esteban E,Baker SE,Bailey S,Needham LL

更新日期：2002-12-01 00:00:00

abstract：:Low-dose extrapolation model selection for evaluating the health effects of environmental pollutants is a key component of the risk assessment process. At a workshop held in Baltimore, Maryland, on 23-24 April 2007, sponsored by U.S. Environmental Protection Agency and Johns Hopkins Risk Sciences and Public Policy Ins...

journal_title：Environmental health perspectives

authors： White RH,Cote I,Zeise L,Fox M,Dominici F,Burke TA,White PD,Hattis DB,Samet JM

更新日期：2009-02-01 00:00:00

abstract：:The physiological function of copper(I)-metallothionein is not well understood. The respiratory function of hemocyanin, a copper(I)-containing respiratory protein found in the hemolymph of many invertebrates, has been known a long time. However, the mechanism by which Cu(I) is inserted into the oxygen-binding site of ...

journal_title：Environmental health perspectives

authors： Brouwer M,Whaling P,Engel DW

更新日期：1986-03-01 00:00:00

abstract：:Chemoprotective phytochemicals exhibit multiple activities and interact with several cellular receptors, including the aryl hydrocarbon (Ah) receptor (AhR). In this study we investigated the AhR agonist/antagonist activities of the following flavonoids: chrysin, phloretin, kaempferol, galangin, naringenin, genistein, ...

journal_title：Environmental health perspectives

authors： Zhang S,Qin C,Safe SH

更新日期：2003-12-01 00:00:00

abstract：:The available data on the influence of selenium on the toxicity of methylmercury and of methylmercury on selenium as a nutrient and toxic agent are reviewed. Selenium as selenite has a relative protective effect on acute and subacute toxicity of methylmercury in the rat and the quail. The protective mechanism is far f...

journal_title：Environmental health perspectives

authors： Skerfving S

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:Prostaglandins (PGs) play key roles in development and maintenance of homeostasis of the adult body. Despite these important roles, it remains unclear whether the PG pathway is a target for endocrine disruption. However, several known endocrine-disrupting compounds (EDCs) share a high degree of structural si...

journal_title：Environmental health perspectives

authors： Kristensen DM,Skalkam ML,Audouze K,Lesné L,Desdoits-Lethimonier C,Frederiksen H,Brunak S,Skakkebæk NE,Jégou B,Hansen JB,Junker S,Leffers H

更新日期：2011-04-01 00:00:00

abstract：:Locating geographic hot spots of cancer may lead to new causal hypotheses and ultimately to new knowledge of cancer-causing factors. The Cape Cod region of Massachusetts has experienced elevated incidence of breast cancer compared with statewide averages. The origins of the excess remain largely unexplained, even afte...

journal_title：Environmental health perspectives

authors： Paulu C,Aschengrau A,Ozonoff D

更新日期：2002-05-01 00:00:00

abstract：:The knowledge of specific problems of occupational cancer in Spain is scarce. The environment of the workplace has improved over the last few years after a long period distinguished by bad working conditions, incomplete legislation, and insufficient safety measures and control. It has been estimated that 3,083,479 wor...

journal_title：Environmental health perspectives

authors： González CA,Agudo A

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Genetics may partially explain observed heterogeneity in associations between traffic-related air pollution and incident asthma. OBJECTIVE:Our aim was to investigate the impact of gene variants associated with oxidative stress and inflammation on associations between air pollution and incident childhood ast...

journal_title：Environmental health perspectives

authors： MacIntyre EA,Brauer M,Melén E,Bauer CP,Bauer M,Berdel D,Bergström A,Brunekreef B,Chan-Yeung M,Klümper C,Fuertes E,Gehring U,Gref A,Heinrich J,Herbarth O,Kerkhof M,Koppelman GH,Kozyrskyj AL,Pershagen G,Postma DS,Th

更新日期：2014-04-01 00:00:00

abstract：:We previously reported that cell cultures of human proximal tubule (HPT) cells respond to ionic cadmium in a manner consistent with well-defined Cd(2+)-elicited responses reported for in vivo systems. However, one unique finding was that the transepithelial electrical resistance and tight junction sealing strands were...

journal_title：Environmental health perspectives

authors： Hazen-Martin DJ,Todd JH,Sens MA,Khan W,Bylander JE,Smyth BJ,Sens DA

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVES:According to the 2007 National Research Council report Toxicology for the Twenty-First Century, modern methods (e.g., "omics," in vitro assays, high-throughput testing, computational methods) will lead to the emergence of a new approach to toxicology. The Salmonella mammalian microsome mutagenicity assay has...

journal_title：Environmental health perspectives

authors： Claxton LD,Umbuzeiro Gde A,DeMarini DM

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Previous research suggests perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) may be associated with adverse pregnancy outcomes. OBJECTIVE:We conducted a population-based study of PFOA and PFOS and birth outcomes from 2005 through 2010 in a Mid-Ohio Valley community exposed to high levels of...

journal_title：Environmental health perspectives

authors： Darrow LA,Stein CR,Steenland K

更新日期：2013-10-01 00:00:00

abstract：:Biological markers of intermediate health outcomes sometimes provide a superior alternative to traditional measures of pollutant-related disease. Some opportunities and methodologic issues associated with using markers are discussed in the context of exposures to four complex mixtures: environmental tobacco smoke and ...

journal_title：Environmental health perspectives

authors： Wilcosky TC

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Early-life exposure to lead is associated with deficits in neurodevelopment and with hematopoietic system toxicity. DNA methylation may be one of the underlying mechanisms for the adverse effects of prenatal lead on the offspring, but epigenome-wide methylation data for low levels of prenatal lead exposure a...

journal_title：Environmental health perspectives

authors： Wu S,Hivert MF,Cardenas A,Zhong J,Rifas-Shiman SL,Agha G,Colicino E,Just AC,Amarasiriwardena C,Lin X,Litonjua AA,DeMeo DL,Gillman MW,Wright RO,Oken E,Baccarelli AA

更新日期：2017-08-25 00:00:00

abstract：:The mutagenic activities of several phthalate esters have been evaluated in an 8-azaguanine resistance assay in Salmonella typhimurium. Three phthalate esters were found to be mutagenic: dimethyl phthalate, diethyl phthalate and di-n-butyl phthalate. A number of other phthalate esters were not found to be mutagenic, i...

journal_title：Environmental health perspectives

authors： Seed JL

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor targeting estrogen receptors (ERs), has been implicated in the promotion of breast cancer. Perinatal exposure of BPA could induce longitudinal alteration of DNA hydroxymethylation in imprinted loci of mouse blood cells. To date, no data has be...

journal_title：Environmental health perspectives

authors： Li Z,Lyu C,Ren Y,Wang H

更新日期：2020-02-01 00:00:00

abstract：:Calcium has been implicated as a regulatory factor in many physiological and pathophysiological processes in the renal cell. Under physiological conditions, the cytosolic free calcium concentration is maintained at approximately 100 nM. Most of the releasable cell Ca2+ resides in the nonmitochondrial compartments. In ...

journal_title：Environmental health perspectives

authors： Bonventre JV

更新日期：1990-03-01 00:00:00

abstract：:Lead-induced nephropathy produces both tubular and interstitial manifestations of cell injury, but the pathophysiology of these lesions is not completely understood. Delineation of the molecular factors underlying renal handling of lead is one of central importance in understanding the mechanisms of renal cell injury ...

journal_title：Environmental health perspectives

authors： Fowler BA,DuVal G

更新日期：1991-02-01 00:00:00

abstract：:As a result of the Leadership Conference on Biomedical Research and the Environment, the Facilities Committee focused its work on the development of best environmental practices at biomedical research facilities at the university and independent research facility level as well as consideration of potential involvement...

journal_title：Environmental health perspectives

authors： Medlin EL,Grupenhoff JT

更新日期：2000-12-01 00:00:00

abstract：:In response to potential threats to human health and fish populations, six states along the east coast of the United States initiated monitoring programs related to Pfiesteria-like organisms in 1998. These actions were taken in the wake of toxic outbreaks of Pfiesteria piscicida Steidinger & Burkholder in Maryland dur...

journal_title：Environmental health perspectives

authors： Magnien RE

更新日期：2001-10-01 00:00:00

abstract：:Articles in the literature on alpha-1 antitrypsin (AAT) deficiency have been interpreted as indicating that AAT deficiency is a rare disease that affects mainly Caucasians (whites) from northern Europe. In a recent publication on the worldwide racial and ethnic distribution of AAT deficiency, new data were presented d...

journal_title：Environmental health perspectives

authors： de Serres FJ

更新日期：2003-12-01 00:00:00

abstract：:Aluminum lactate [Al(lact)3] (hydrophilic, hydrolytically unstable) and aluminum acetylacetonate [Al(acae)3] (lipophilic, hydrolytically stable) were tested as potential toxicants to rabbits upon IV administration both as aqueous solutions and as liposome suspensions. Both chemicals behaved as cardiotoxic agents when ...

journal_title：Environmental health perspectives

authors： Bombi GG,Corain B,Favarato M,Giordano R,Nicolini M,Perazzolo M,Tapparo A,Zatta P

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:The mortality impacts of hot and cold temperatures have been thoroughly documented, with most locations reporting a U-shaped relationship with a minimum mortality temperature (MMT) at which mortality is lowest. How MMT may have evolved over previous decades as the global mean surface temperature has increase...

journal_title：Environmental health perspectives

authors： Åström DO,Tornevi A,Ebi KL,Rocklöv J,Forsberg B

更新日期：2016-06-01 00:00:00

abstract：:The cytotoxic action of a series of mineral dusts has been studied using Chinese hamster V79-4 cells obtained from three separate laboratories in the UK. The dusts which have been studied include samples of asbestos from the Union Internationale Contre le Cancer reference series and an internationally available sample...

journal_title：Environmental health perspectives

authors： Lock SO,Chamberlain M

更新日期：1983-09-01 00:00:00