Prognosis of photoparoxysmal response in nonepileptic patients.

Abstract:

:Photoparoxysmal response (PPR) is sometimes incidentally encountered in EEGs performed for evaluation of nonepileptic symptoms. We conducted the first long-term study of a cohort of nonepileptic patients to determine their risk of having seizures subsequent to incidental recording of PPR. After 6 to 12 years (mean, 9 years), none of the 33 patients had had epileptic seizures. To identify prognostic factors associated with PPR, we performed a case-control study comparing the cohort with 33 age-matched patients who had had epileptic seizures prior to PPR recording. There was no statistically significant difference between the two groups with respect to the clinical or EEG data. Morphology of the PPR discharge was not different between the two groups. Contrary to what is widely believed, persistence of PPR discharges beyond stimulation was not associated with a high risk of developing seizures. Prognosis of PPR is age-dependent and seems favorable in adults without previous epileptic seizures.

journal_name

Neurology

journal_title

Neurology

authors

So EL,Ruggles KH,Ahmann PA,Olson KA

doi

10.1212/wnl.43.9.1719

subject

Has Abstract

pub_date

1993-09-01 00:00:00

pages

1719-22

issue

9

eissn

0028-3878

issn

1526-632X

journal_volume

43

pub_type

杂志文章
  • Local cerebral metabolism during partial seizures.

    abstract::Interictal and ictal fluorodeoxyglucose scans were obtained with positron CT from four patients with spontaneous recurrent partial seizures, one with epilepsia partialis continua, and one with a single partial seizure induced by electrical stimulation of the hippocampus. Ictal metabolic patterns were different for eac...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.33.4.400

    authors: Engel J Jr,Kuhl DE,Phelps ME,Rausch R,Nuwer M

    更新日期:1983-04-01 00:00:00

  • Adverse effects of subthalamic nucleus DBS in a patient with multiple system atrophy.

    abstract::A 59-year-old woman with levodopa-responsive parkinsonism complicated by motor fluctuations and generalized levodopa dyskinesia underwent bilateral subthalamic deep brain stimulation (STN DBS) 7 years after symptom onset. DBS improved levodopa-responsive upper extremity bradykinesia but aggravated speech, swallowing, ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000073986.74883.36

    authors: Tarsy D,Apetauerova D,Ryan P,Norregaard T

    更新日期:2003-07-22 00:00:00

  • Characteristics and predictors of 7- and 30-day hospital readmissions to pediatric neurology.

    abstract:OBJECTIVE:Hospital readmission is an important quality improvement measure that has not been well-studied in pediatric neurology. We examined predictors of 7-day and 30-day readmissions for pediatric patients hospitalized with a neurologic diagnosis. METHODS:This was a retrospective study of hospital readmission rates...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000007280

    authors: Hong A,Shah Y,Singh K,Karkare S,Kothare S

    更新日期:2019-04-16 00:00:00

  • Tobacco smoking and the risk of Parkinson disease: A 65-year follow-up of 30,000 male British doctors.

    abstract:OBJECTIVE:To investigate the causal relevance of current tobacco smoking for the risk of Parkinson disease (PD). METHODS:We compared the risks of death from PD with smoking habits in 30,000 male doctors in the British Doctors cohort study in 1951 and in survivors who had been resurveyed periodically for 5 decades. Cau...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000009437

    authors: Mappin-Kasirer B,Pan H,Lewington S,Kizza J,Gray R,Clarke R,Peto R

    更新日期:2020-05-19 00:00:00

  • Fatal ataxic encephalopathy and carnitine acetyltransferase deficiency: a functional defect of pyruvate oxidation?

    abstract::A 3-year 8-month-old girl died after 14 months of illness characterized by episodes of intermittent ataxia associated with oculomotor palsy, hypotonia, mental confusion, and disturbances of consciousness. In the last 4 months of life, there were signs of liver dysfunction. Pyruvate dehydrogenase and alpha-ketoglutarat...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.29.12.1578

    authors: DiDonato S,Rimoldi M,Moise A,Bertagnoglio B,Uziel G

    更新日期:1979-12-01 00:00:00

  • Lapse of consciousness and automatisms in temporal lobe epilepsy: a videotape analysis.

    abstract::Videotape analysis of 76 attacks in 14 epileptics showed two electro-clinical types of psychomotor attacks. The first and most common type had three clinical phases, consisting of an initial motionless stare, stereotyped movements, and reactive automatisms during impaired consciousness. The second and less common type...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.27.2.144

    authors: Escueta AV,Kunze U,Waddell G,Boxley J,Nadel A

    更新日期:1977-02-01 00:00:00

  • Extending neurologic services to rural children.

    abstract::The University of Kentucky provides neurologic services to rural children by a traveling clinic. In 1978, 438 children (including 231 new patients) made 646 clinic visits. The primary diagnoses were appropriate for a neurology clinic; epilepsy was the most common (74 of 231) among new patients. A community survey of s...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.29.9_part_1.1298

    authors: Baumann RJ,Leonidakis MG

    更新日期:1979-09-01 00:00:00

  • Gram-negative bacterial molecules associate with Alzheimer disease pathology.

    abstract:OBJECTIVE:We determined whether Gram-negative bacterial molecules are associated with Alzheimer disease (AD) neuropathology given that previous studies demonstrate Gram-negative Escherichia coli bacteria can form extracellular amyloid and Gram-negative bacteria have been reported as the predominant bacteria found in no...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000003391

    authors: Zhan X,Stamova B,Jin LW,DeCarli C,Phinney B,Sharp FR

    更新日期:2016-11-29 00:00:00

  • A score that predicts 1-year functional status in patients with anti-NMDA receptor encephalitis.

    abstract:OBJECTIVE:To construct a grading score that predicts neurologic function 1 year after diagnosis of anti-NMDA receptor (NMDAR) encephalitis. METHODS:Three hundred eighty-two patients with detailed information and functional status at 1 year were studied. Factors associated with poor status (defined as modified Rankin S...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000006783

    authors: Balu R,McCracken L,Lancaster E,Graus F,Dalmau J,Titulaer MJ

    更新日期:2019-01-15 00:00:00

  • Hippocampal removal affects visual but not auditory naming.

    abstract:OBJECTIVE:Dominant, left anteromedial temporal lobe resection (AMTLR) for seizure control carries risks to verbal episodic memory and visual object naming. Consistent with traditional thinking, verbal memory decline is considered a consequence of hippocampal removal and naming decline has been attributed to lateral tem...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e3181dd40f0

    authors: Hamberger MJ,Seidel WT,McKhann GM 2nd,Goodman RR

    更新日期:2010-05-11 00:00:00

  • Nav1.7-related small fiber neuropathy: impaired slow-inactivation and DRG neuron hyperexcitability.

    abstract:OBJECTIVES:Although small fiber neuropathy (SFN) often occurs without apparent cause, the molecular etiology of idiopathic SFN (I-SFN) has remained enigmatic. Sodium channel Na(v)1.7 is preferentially expressed within dorsal root ganglion (DRG) and sympathetic ganglion neurons and their small-diameter peripheral axons....

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e3182574f12

    authors: Han C,Hoeijmakers JG,Ahn HS,Zhao P,Shah P,Lauria G,Gerrits MM,te Morsche RH,Dib-Hajj SD,Drenth JP,Faber CG,Merkies IS,Waxman SG

    更新日期:2012-05-22 00:00:00

  • Delineation of the movement disorders associated with FOXG1 mutations.

    abstract:OBJECTIVE:The primary objective of this research was to characterize the movement disorders associated with FOXG1 mutations. METHODS:We identified patients with FOXG1 mutations who were referred to either a tertiary movement disorder clinic or tertiary epilepsy service and retrospectively reviewed medical records, cli...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000002585

    authors: Papandreou A,Schneider RB,Augustine EF,Ng J,Mankad K,Meyer E,McTague A,Ngoh A,Hemingway C,Robinson R,Varadkar SM,Kinali M,Salpietro V,O'Driscoll MC,Basheer SN,Webster RI,Mohammad SS,Pula S,McGowan M,Trump N,Jenkin

    更新日期:2016-05-10 00:00:00

  • Alterations of skin glycosaminoglycans in patients with ALS.

    abstract:BACKGROUND AND OBJECTIVE:Collagen abnormalities of skin have been reported among patients with ALS. However, little is known concerning glycosaminoglycans of the skin in ALS. Our objective was to clarify morphologic and biochemical findings of skin glycosaminoglycans among patients with ALS. METHODS:We performed morph...

    journal_title:Neurology

    pub_type: 临床试验,杂志文章

    doi:10.1212/wnl.51.2.399

    authors: Ono S,Imai T,Aso A,Yamano T,Shimizu N,Nagao K

    更新日期:1998-08-01 00:00:00

  • Detection of subtle gait disturbance and future fall risk in early multiple sclerosis.

    abstract:OBJECTIVE:To test the hypothesis that higher-challenge gait and balance tasks are more sensitive than traditional metrics to subtle patient-reported gait dysfunction and future fall risk in early multiple sclerosis (MS). METHODS:Persons with early MS (n = 185; ≤5 years diagnosed) reported gait function (MS Walking Sca...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000008938

    authors: Brandstadter R,Ayeni O,Krieger SC,Harel NY,Escalon MX,Katz Sand I,Leavitt VM,Fabian MT,Buyukturkoglu K,Klineova S,Riley CS,Lublin FD,Miller AE,Sumowski JF

    更新日期:2020-03-31 00:00:00

  • Rate of motor response to oral levodopa and the clinical progression of Parkinson's disease.

    abstract::We investigated the relationship between the rate of motor response after a standard levodopa oral dose and drug dynamic variables and disease-related factors in 66 patients with Parkinson's disease. Time to maximum finger tapping effect was positively correlated with matched duration of levodopa dose response and fel...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.46.4.1055

    authors: Contin M,Riva R,Martinelli P,Triggs EJ,Albani F,Baruzzi A

    更新日期:1996-04-01 00:00:00

  • Motor axon loss is associated with hand dysfunction in Charcot-Marie-Tooth disease 1a.

    abstract:BACKGROUND:Charcot Marie Tooth type 1a (CMT1a) is a primarily demyelinating neuropathy, characterized by slowly progressive muscle weakness, atrophy, and sensory loss, and is most pronounced in both feet and hands. There is increasing evidence that muscle weakness is determined by motor axonal dysfunction. OBJECTIVE:T...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000327643.05073.eb

    authors: Videler AJ,van Dijk JP,Beelen A,de Visser M,Nollet F,van Schaik IN

    更新日期:2008-10-14 00:00:00

  • Primary Sjögren's syndrome in patients with multiple sclerosis.

    abstract::The relationship between multiple sclerosis (MS) and primary Sjögren's syndrome (PSS) is ambiguous; it was suggested that some patients diagnosed with MS may instead have PSS. In a recent epidemiologic study, the prevalence of PSS was 2.7% in southern Sweden. We randomly selected 30 patients with definite MS from our ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.42.4.845

    authors: Sandberg-Wollheim M,Axéll T,Hansen BU,Henricsson V,Ingesson E,Jacobsson L,Larsson A,Lieberkind K,Manthorpe R

    更新日期:1992-04-01 00:00:00

  • Syndromes dominated by apraxia of speech show distinct characteristics from agrammatic PPA.

    abstract:OBJECTIVE:We assessed whether clinical and imaging features of subjects with apraxia of speech (AOS) more severe than aphasia (dominant AOS) are more similar to agrammatic primary progressive aphasia (agPPA) or to primary progressive AOS (PPAOS). METHODS:Sixty-seven subjects (PPAOS = 18, dominant AOS = 10, agPPA = 9, ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e31829c5ed5

    authors: Josephs KA,Duffy JR,Strand EA,Machulda MM,Senjem ML,Lowe VJ,Jack CR Jr,Whitwell JL

    更新日期:2013-07-23 00:00:00

  • Current treatment pathways in ALS: a European perspective.

    abstract::This article presents the findings relating to the European subgroup of 91 patients in an international survey of the current diagnosis and treatment of patients with amyotrophic lateral sclerosis (ALS). The mean time between first symptoms and first consultation with a physician was 4.9 months, and mean delay in seei...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:

    authors: Dengler R

    更新日期:1999-01-01 00:00:00

  • Varicella-zoster virus DNA in CSF and arteries in delayed contralateral hemiplegia: evidence for viral invasion of cerebral arteries.

    abstract::A 78-year-old woman presented with a right basal ganglia infarct 6 weeks after a left herpes zoster ophthalmicus. MR angiography showed focal segmental stenosis of the proximal segments of the anterior, middle, and posterior cerebral arteries. Varicella DNA was detected in the CSF by polymerase chain reaction (PCR). T...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.47.2.569

    authors: Melanson M,Chalk C,Georgevich L,Fett K,Lapierre Y,Duong H,Richardson J,Marineau C,Rouleau GA

    更新日期:1996-08-01 00:00:00

  • Brain N-acetylaspartate is elevated in Pelizaeus-Merzbacher disease with PLP1 duplication.

    abstract:OBJECTIVE:To assess alterations in brain metabolites of patients with Pelizaeus-Merzbacher disease (PMD) with the proteolipid protein gene 1 (PLP1) duplications using quantitative proton MRS. METHODS:Five unrelated male Japanese patients with PMD with PLP1 duplications were analyzed using automated proton brain examin...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.58.2.237

    authors: Takanashi J,Inoue K,Tomita M,Kurihara A,Morita F,Ikehira H,Tanada S,Yoshitome E,Kohno Y

    更新日期:2002-01-22 00:00:00

  • Thymus changes in anti-MuSK-positive and -negative myasthenia gravis.

    abstract::Morphologic findings of thymuses from 32 anti-acetylcholine receptor (AChR)-negative myasthenia gravis patients, 12 with and 20 without antibodies against the muscle-specific kinase (MuSK), were compared with those from 30 AChR-positive subjects. In contrast with the high frequency of thymic hyperplastic changes in AC...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.WNL.0000150587.71497.B6

    authors: Lauriola L,Ranelletti F,Maggiano N,Guerriero M,Punzi C,Marsili F,Bartoccioni E,Evoli A

    更新日期:2005-02-08 00:00:00

  • Natural history of cavernous malformation: Systematic review and meta-analysis of 25 studies.

    abstract:OBJECTIVE:We pooled the results of studies on natural history of cavernous malformations (CM) to calculate point estimates and investigate main sources of heterogeneity. METHODS:We searched MEDLINE, EMBASE, and ISI Web of Science for relevant studies published before May 2015. We used fixed or random effects models an...

    journal_title:Neurology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1212/WNL.0000000000002701

    authors: Taslimi S,Modabbernia A,Amin-Hanjani S,Barker FG 2nd,Macdonald RL

    更新日期:2016-05-24 00:00:00

  • Practical utility of amyloid and FDG-PET in an academic dementia center.

    abstract:OBJECTIVE:To evaluate the effect of amyloid imaging on clinical decision making. METHODS:We conducted a retrospective analysis of 140 cognitively impaired patients (mean age 65.0 years, 46% primary β-amyloid (Aβ) diagnosis, mean Mini-Mental State Examination 22.3) who underwent amyloid (Pittsburgh compound B [PiB]) PE...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000000032

    authors: Sánchez-Juan P,Ghosh PM,Hagen J,Gesierich B,Henry M,Grinberg LT,O'Neil JP,Janabi M,Huang EJ,Trojanowski JQ,Vinters HV,Gorno-Tempini M,Seeley WW,Boxer AL,Rosen HJ,Kramer JH,Miller BL,Jagust WJ,Rabinovici GD

    更新日期:2014-01-21 00:00:00

  • Circadian sneezing.

    abstract::Prompted by the observation that a fellow medical student sneezed at about the same time in class every morning, we recorded the time of each of the 118 sneezes she made on 69 days over a 6.5-month period. Analysis of the sneeze times with the goodness-of-fit test revealed a highly nonuniform distribution (p < 0.0001)...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.44.3_part_1.369

    authors: Grant AC,Roter EP

    更新日期:1994-03-01 00:00:00

  • Reemergence of activation with poststroke somatosensory recovery: a serial fMRI case study.

    abstract::The authors demonstrate the potential for poststroke return of activation in regions normally involved in touch discrimination in a serial, whole-brain fMRI study of a patient with marked sensory loss followed by good recovery. A return of activation in ipsilesional primary and bilateral secondary somatosensory cortic...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.59.5.749

    authors: Carey LM,Abbott DF,Puce A,Jackson GD,Syngeniotis A,Donnan GA

    更新日期:2002-09-10 00:00:00

  • SCN2A mutation associated with neonatal epilepsy, late-onset episodic ataxia, myoclonus, and pain.

    abstract:BACKGROUND:Inherited and de novo mutations in sodium channel genes underlie a variety of channelopathies. Mutations in SCN2A, encoding the brain sodium channel Na(V)1.2, have previously been reported to be associated with benign familial neonatal infantile seizures, febrile seizures plus, and intractable epilepsy of in...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0b013e3181f8812e

    authors: Liao Y,Anttonen AK,Liukkonen E,Gaily E,Maljevic S,Schubert S,Bellan-Koch A,Petrou S,Ahonen VE,Lerche H,Lehesjoki AE

    更新日期:2010-10-19 00:00:00

  • Shortening reaction of human tibialis anterior.

    abstract::The shortening reaction of tibialis anterior was observed in 6 of 25 normal subjects, in 6 of 40 patients with upper motor neuron syndromes, and in 11 of 17 patients with Parkinson's disease. The latency of the shortening reaction was comparable with that of the latter part of the long-latency stretch reflexes. The ma...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.34.2.242

    authors: Berardelli A,Hallett M

    更新日期:1984-02-01 00:00:00

  • Relation between MR abnormalities and patterns of cognitive impairment in multiple sclerosis.

    abstract:OBJECTIVE:This study correlated the extent of abnormalities detected by different magnetic resonance imaging (MRI) techniques [proton density (PD)-weighted, T1-weighted, and magnetization transfer imaging (MTI)] with the overall cognitive, frontal lobe, and memory impairments in patients with MS. PATIENTS:There were 3...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.50.6.1601

    authors: Rovaris M,Filippi M,Falautano M,Minicucci L,Rocca MA,Martinelli V,Comi G

    更新日期:1998-06-01 00:00:00

  • Corpus callosotomy for epilepsy. I. Seizure effects.

    abstract::Twenty-two patients were analyzed 2 or more years after corpus callosum section (9 partial, 13 total). Forty-one percent had class 1 outcome (elimination of secondarily generalized and complex partial seizures), 32% had class 2 outcome (elimination of secondarily generalized seizures), and 27% had class 3 outcome (no ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/wnl.38.1.19

    authors: Spencer SS,Spencer DD,Williamson PD,Sass K,Novelly RA,Mattson RH

    更新日期:1988-01-01 00:00:00