Abstract:
:Sarcomas in the forearm and hand are very rare, accounting for less than 1% of all upper-limb tumors and clinical outcomes after surgery and adjuvant therapies are uncertain. The forearm and hand present specific challenges due to their unique anatomical structures. There is little soft tissue and each compartment is narrow, such important structures exist in close proximity. Anatomic constraints make it difficult to achieve wide surgical margins. Although sarcomas often metastasize to the lung, the overall survival rate is excellent. Wide marginal resection during initial surgery is the most predictive factor for tumor control. The role of reconstructive surgery following wide excision for sarcoma of the forearm and hand is even more important than elsewhere in the body because excision is likely to cause bone, tendon and nerve defects, leading to severe functional deficits. Multiple options exist for bony and soft tissue reconstruction of the upper limb, with the choice dependent upon tumor type, wound characteristics, surgeon preference and the patients' functional requirements. Success should be measured not just by stable wound coverage but also by preservation of patient's health, limb cosmesis, sensation and function. Careful preoperative planning with consideration of all the possible resected structures should improve patient outcomes.
journal_name
Anticancer Resjournal_title
Anticancer researchauthors
Muramatsu K,Ihara K,Yoshida K,Tominaga Y,Hashimoto T,Taguchi Tsubject
Has Abstractpub_date
2013-10-01 00:00:00pages
4175-82issue
10eissn
0250-7005issn
1791-7530pii
33/10/4175journal_volume
33pub_type
杂志文章,评审abstract:BACKGROUND/AIM:Intraperitoneal chemotherapy with taxanes provides high locoregional drug concentrations. Regarding their synergy with hyperthermia, results have been inconclusive. In this in vitro study, the thermal enhancement of the effect of paclitaxel and docetaxel on ovarian cancer cells under conditions mimicking...
journal_title:Anticancer research
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更新日期:2020-12-01 00:00:00
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journal_title:Anticancer research
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更新日期:2008-11-01 00:00:00
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journal_title:Anticancer research
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更新日期:2009-09-01 00:00:00
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更新日期:2008-05-01 00:00:00
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更新日期:2011-05-01 00:00:00
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journal_title:Anticancer research
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更新日期:2006-05-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章,评审
doi:
更新日期:2007-03-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
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更新日期:2010-06-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2001-11-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
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更新日期:1996-03-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章,评审
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更新日期:2018-02-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2015-03-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
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更新日期:2018-02-01 00:00:00
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journal_title:Anticancer research
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doi:
更新日期:2015-01-01 00:00:00
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doi:
更新日期:2010-11-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2014-10-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2004-09-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00
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journal_title:Anticancer research
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更新日期:2010-09-01 00:00:00
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更新日期:2013-11-01 00:00:00
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journal_title:Anticancer research
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更新日期:2003-11-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2007-11-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章,评审
doi:
更新日期:1993-11-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:1998-07-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2015-08-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
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journal_title:Anticancer research
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doi:
更新日期:2007-07-01 00:00:00
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journal_title:Anticancer research
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1998-05-01 00:00:00