MR imaging of protein folding in vitro employing nuclear-Overhauser-mediated saturation transfer.

abstract：:The majority of functional MRI studies of pain processing in the brain use the blood oxygenation level-dependent (BOLD) imaging approach. However, the BOLD signal is complex as it depends on simultaneous changes in blood flow, vascular volume and oxygen metabolism. Arterial spin labeling (ASL) perfusion imaging is ano...

journal_title：NMR in biomedicine

authors： Maleki N,Brawn J,Barmettler G,Borsook D,Becerra L

更新日期：2013-06-01 00:00:00

abstract：:By quantification of brain metabolites, localized brain proton MRS can non-invasively provide biochemical information from distinct regions of the brain. Quantification of short-TE signals is usually based on a metabolite basis set. The basis set can be obtained by two approaches: (1) by measuring the signals of metab...

journal_title：NMR in biomedicine

authors： Cudalbu C,Cavassila S,Rabeson H,van Ormondt D,Graveron-Demilly D

更新日期：2008-07-01 00:00:00

abstract：:The elimination of so-called background fields is an essential step in phase MRI and quantitative susceptibility mapping (QSM). Background fields, which are caused by sources outside the region of interest (ROI), are often one to two orders of magnitude stronger than tissue-related field variations from within the ROI...

journal_title：NMR in biomedicine

authors： Schweser F,Robinson SD,de Rochefort L,Li W,Bredies K

更新日期：2017-04-01 00:00:00

abstract：:While phase imaging with a gradient echo (GRE) sequence is popular, phase imaging with balanced steady-state free precession (bSSFP) has been underexplored. The purpose of this study was to investigate anatomical and functional phase imaging with multiple phase-cycled bSSFP, in expectation of increasing spatial covera...

journal_title：NMR in biomedicine

authors： Kim JW,Kim SG,Park SH

更新日期：2017-06-01 00:00:00

abstract：:Acute kidney injury (AKI) in mice caused by sustained ischemia followed by reperfusion is associated with acute tubular necrosis and renal dysfunctional blood flow. Although the principal role of the kidney is the maintenance of acid-base balance, current imaging approaches are unable to assess this important paramete...

journal_title：NMR in biomedicine

authors： Longo DL,Cutrin JC,Michelotti F,Irrera P,Aime S

更新日期：2017-07-01 00:00:00

abstract：:An indirect method for in vivo T2 mapping of 13 C-labeled metabolites using T2 and T2 * information of water protons obtained a priori is proposed. The T2 values of 13 C metabolites are inferred using the relationship to T2 ' of coexisting 1 H and the T2 * of 13 C metabolites, which is measured using routine hyperpola...

journal_title：NMR in biomedicine

authors： Joe E,Lee H,Lee J,Yang S,Choi YS,Wang E,Song HT,Kim DH

更新日期：2017-05-01 00:00:00

abstract：:Human tumor and skeletal muscle tissue was studied by means of in vivo 1H, 31P, and 13C MRS. The examinations were performed with a 1.5 T whole-body MR scanner equipped with a second RF system. Localized 1H and broadband proton-decoupled 31P and 13C MR spectra were obtained in measurement times of 5, 10 and 33 min, re...

journal_title：NMR in biomedicine

authors： Bachert P,Bellemann ME,Layer G,Koch T,Semmler W,Lorenz WJ

更新日期：1992-07-01 00:00:00

abstract：:Determination of the apparent diffusion coefficient (ADC) of the prostate in men (n = 60) with raised prostate-specific antigen (PSA) or an abnormal digital rectal examination (DRE) prior to transrectal ultrasound (TRUS) guided biopsy using endorectal DWI is reported. Patients were categorized into different groups ba...

journal_title：NMR in biomedicine

authors： Kumar V,Jagannathan NR,Kumar R,Thulkar S,Gupta SD,Dwivedi SN,Hemal AK,Gupta NP

更新日期：2007-08-01 00:00:00

abstract：:During the measurement of hyperpolarized 129 Xe magnetic resonance imaging (MRI), the diffusion-weighted imaging (DWI) technique provides valuable information for the assessment of lung morphometry at the alveolar level, whereas the chemical shift saturation recovery (CSSR) technique can evaluate the gas exchange func...

journal_title：NMR in biomedicine

authors： Zhong J,Zhang H,Ruan W,Xie J,Li H,Deng H,Han Y,Sun X,Ye C,Zhou X

更新日期：2017-08-01 00:00:00

abstract：:In order to keep subscribers up-to-date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of NMR in biomedicine. Each bibliography is divided into 9 sections: 1 Books, Re...

journal_title：NMR in biomedicine

authors： Wennerberg AB,Jonsson T,Forssberg H,Li TQ

更新日期：2001-02-01 00:00:00

abstract：:In this work we introduce the concept of correlation chemical shift imaging (CCSI). Novel CCSI pulse sequences are demonstrated on clinical scanners for two-dimensional Correlation Spectroscopy (COSY) and Total Correlation Spectroscopy (TOCSY) imaging experiments. To date there has been limited progress reported towar...

journal_title：NMR in biomedicine

authors： Andronesi OC,Gagoski BA,Adalsteinsson E,Sorensen AG

更新日期：2012-02-01 00:00:00

abstract：:The aim of this study was to investigate the diffusion time dependence of signal-versus-b curves obtained from diffusion-weighted magnetic resonance imaging (DW-MRI) of sub-acute ischaemic lesions in stroke patients. In this case series study, 16 patients with sub-acute ischaemic stroke were examined with DW-MRI using...

journal_title：NMR in biomedicine

authors： Lätt J,Nilsson M,van Westen D,Wirestam R,Ståhlberg F,Brockstedt S

更新日期：2009-07-01 00:00:00

abstract：:Lung cancer is a primary cause of cancer deaths worldwide. Timely detection of this pathology is necessary to delay or interrupt lung cancer progression, ultimately resulting in a possible better prognosis for the patient. In this context, magnetic resonance imaging (MRI) is especially promising. Ultra-short echo time...

journal_title：NMR in biomedicine

authors： Bianchi A,Gobbo OL,Dufort S,Sancey L,Lux F,Tillement O,Coll JL,Crémillieux Y

更新日期：2017-11-01 00:00:00

abstract：:In this study we aimed to assess the effects of continuous formalin fixation on diffusion and relaxation metrics of the ex vivo porcine heart at 7 T. Magnetic resonance imaging was performed on eight piglet hearts using a 7 T whole body system. Hearts were measured fresh within 3 hours of cardiac arrest followed by im...

journal_title：NMR in biomedicine

authors： Lohr D,Terekhov M,Veit F,Schreiber LM

更新日期：2020-07-01 00:00:00

abstract：:γ-Aminobutyric acid (GABA) and glutamate (Glu), major neurotransmitters in the brain, are recycled through glutamine (Gln). All three metabolites can be measured by magnetic resonance spectroscopy in vivo, although GABA measurement at 3 T requires an extra editing acquisition, such as Mescher-Garwood point-resolved sp...

journal_title：NMR in biomedicine

authors： Sanaei Nezhad F,Anton A,Michou E,Jung J,Parkes LM,Williams SR

更新日期：2018-01-01 00:00:00

abstract：:A study was undertaken to determine if the vascular characteristics measured by dynamic contrast-enhanced magnetic resonance imaging (primarily permeability surface area product and extracellular-extravascular tissue volume fraction) would be beneficial in explaining the inter-lesion metabolic heterogeneity displayed ...

journal_title：NMR in biomedicine

authors： Manton DJ,Lowry M,Rowland-Hill C,Crooks D,Mathew B,Turnbull LW

更新日期：2000-12-01 00:00:00

abstract：:Central obesity is the hallmark of a number of non-inheritable disorders. The advent of imaging techniques such as MRI has allowed for a fast and accurate assessment of body fat content and distribution. However, image analysis continues to be one of the major obstacles to the use of MRI in large-scale studies. In thi...

journal_title：NMR in biomedicine

authors： Borga M,Thomas EL,Romu T,Rosander J,Fitzpatrick J,Dahlqvist Leinhard O,Bell JD

更新日期：2015-12-01 00:00:00

abstract：:In vivo metabolic imaging using hyperpolarized [1-(13)C]pyruvate provides localized biochemical information and is particularly useful in detecting early disease changes, as well as monitoring disease progression and treatment response. However, a major limitation of hyperpolarized magnetization is its unrecoverable d...

journal_title：NMR in biomedicine

authors： Chen WC,Teo XQ,Lee MY,Radda GK,Lee P

更新日期：2015-08-01 00:00:00

abstract：:The cuprizone mouse model of demyelination was used to investigate the influence that white matter changes have on different magnetic resonance imaging results. In vivo T2 -weighted and magnetization transfer images (MTIs) were acquired weekly in control (n = 5) and cuprizone-fed (n = 5) mice, with significant increas...

journal_title：NMR in biomedicine

authors： Thiessen JD,Zhang Y,Zhang H,Wang L,Buist R,Del Bigio MR,Kong J,Li XM,Martin M

更新日期：2013-11-01 00:00:00

abstract：:An outline is presented of metabolite-specific in vivo NMR spectroscopy (particularly in brain). It reviews from a physical spectroscopist's perspective, the need for and the methods of observation of, individual metabolite resonances. ...

journal_title：NMR in biomedicine

authors： Allen PS,Thompson RB,Wilman AH

更新日期：1997-12-01 00:00:00

abstract：:Tumor metabolism is directly coupled to tumor blood flow (TBF) and both metabolism and blood flow may be determinants of tumor response to treatment. Since NMR has been used extensively to monitor tumor metabolism noninvasively, development of NMR-based methods for TBF measurement was motivated by the desire to examin...

journal_title：NMR in biomedicine

authors： Evelhoch JL

更新日期：1992-09-01 00:00:00

abstract：:Early imaging or blood biomarkers of tumor response is needed to customize anti-tumor therapy on an individual basis. This study evaluates the sensitivity and relevance of five potential MRI biomarkers. Sixty nude rats were implanted with human glioma cells (U-87 MG) and randomized into three groups: one group receive...

journal_title：NMR in biomedicine

authors： Lemasson B,Christen T,Tizon X,Farion R,Fondraz N,Provent P,Segebarth C,Barbier EL,Genne P,Duchamp O,Remy C

更新日期：2011-06-01 00:00:00

abstract：:This study investigated the association between the total choline (tCho) concentration and the clinical characteristics and biomarker status of breast cancer. Sixty-two patients with breast cancer, 1.5  cm or larger in size on MR images, were studied. The tCho concentration was correlated with the MRI features, contra...

journal_title：NMR in biomedicine

authors： Chen JH,Mehta RS,Baek HM,Nie K,Liu H,Lin MQ,Yu HJ,Nalcioglu O,Su MY

更新日期：2011-04-01 00:00:00

abstract：:A novel polarizer based on the dissolution-dynamic nuclear polarization (DNP) method has been designed, built and tested. The polarizer differs from those previously described by being designed with sterile use intent and being compatible with clinical use. The main features are: (1) an integral, disposable fluid path...

journal_title：NMR in biomedicine

authors： Ardenkjaer-Larsen JH,Leach AM,Clarke N,Urbahn J,Anderson D,Skloss TW

更新日期：2011-10-01 00:00:00

abstract：:In recent years considerable effort has been devoted to applying pattern recognition techniques to the complex task of data analysis in magnetic resonance spectroscopy. It may be argued that such techniques will facilitate putting MRS technology to practical clinical use. This paper reviews approaches of pattern recog...

journal_title：NMR in biomedicine

authors： el-Deredy W

更新日期：1997-05-01 00:00:00

abstract：:A method to extract shapes of bubble polyhedra from three-dimensional nuclear magnetic resonance image data of foam has been developed. The method consists of four steps: first, to compute series of maximum intensity projection images from the three-dimensional NMR image data of foam to visualize the network structure...

journal_title：NMR in biomedicine

authors： Kashiwagi K,Kose K

更新日期：1997-01-01 00:00:00

abstract：:Qualitative and quantitative (1) H NMR analysis of lipid extracts of gallbladder tissue in chronic cholecystitis (CC, benign) (n = 14), xanthogranulomatous cholecystitis (XGC, intermediate) (n = 9) and gallbladder cancer (GBC, malignant) (n = 8) was carried out to understand the mechanisms involved in the transformati...

journal_title：NMR in biomedicine

authors： Jayalakshmi K,Sonkar K,Behari A,Kapoor VK,Sinha N

更新日期：2011-05-01 00:00:00

abstract：:Electric properties tomography (EPT) derives the patient's electric properties, i.e. conductivity and permittivity, using standard magnetic resonance (MR) systems and standard MR sequences. Thus, EPT does not apply externally mounted electrodes, currents or radiofrequency (RF) probes, as is the case in competing techn...

journal_title：NMR in biomedicine

authors： Katscher U,van den Berg CAT

更新日期：2017-08-01 00:00:00

abstract：:Owing to the small quantity of tissue available in human biopsy specimens, aqueous and lipid components often have to be determined in the same tissue sample. Perchloric acid (PCA) used for the extraction of aqueous metabolites has a deleterious effect on lipid components; the severity of the damage is not known. In t...

journal_title：NMR in biomedicine

authors： Srivastava NK,Pradhan S,Mittal B,Kumar R,Pandey CM,Gowda GA

更新日期：2008-02-01 00:00:00

abstract：:In many studies, it has been demonstrated that (1)H MRSI of the human prostate has great potential to aid prostate cancer management, e.g. in the detection and localisation of cancer foci in the prostate or in the assessment of its aggressiveness. It is particularly powerful in combination with T2 -weighted MRI. Never...

journal_title：NMR in biomedicine

authors： Kobus T,Wright AJ,Scheenen TW,Heerschap A

更新日期：2014-01-01 00:00:00