Abstract:
:We have studied the effect of butyrate on mammary tumorigenesis by 7,12-dimethylbenz(a)anthracene. As reported previously, a high incidence of mammary tumors was observed in rats fed a basal diet containing 20% margarine. However, the enhancing effect of margarine was inhibited when sodium butyrate was supplemented in the high margarine diet. Sodium butyrate did not cause any effect when it was supplemented in the basal diet. The result suggests a possibility that a part of the inhibitory effect of butter on mammary tumorigenesis, which we had previously reported, was caused by butyrate milk lipids.
journal_name
Oncologyjournal_title
Oncologyauthors
Yanagi S,Yamashita M,Imai Sdoi
10.1159/000227178subject
Has Abstractpub_date
1993-07-01 00:00:00pages
201-4issue
4eissn
0030-2414issn
1423-0232journal_volume
50pub_type
杂志文章相关文献
ONCOLOGY文献大全abstract::C-reactive protein (CRP) has been found to be ubiquitous in sera when determined by a highly sensitive methods such as radioimmunoassay. Patients with some tumors appear to have much higher serum levels of CRP than others; in these, CRP seems to reflect the tumor burden. There is a positive correlation with TNM stagin...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000225572
更新日期:1981-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study is to investigate whether the Ile646Val (2073A>G) polymorphism in the kinase-binding domain of A-kinase anchoring protein 10 (AKAP10) is related to the risk of colorectal cancer (CRC), clinicopathological variables and the environmental factors for the development of CRC. METHODS:Ap...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000201572
更新日期:2009-01-01 00:00:00
abstract::Retinoids are differentiating agents that have been used successfully for the treatment of acute promyelocytic leukemia. When combined with interferons, they are active in preventing second malignancies in patients with head and neck cancer. Our previous studies have demonstrated cytostatic effects of alltrans-retinoi...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000227583
更新日期:1996-07-01 00:00:00
abstract::Thirteen samples of gastric tumors that had developed in the remnant stomach (remnant gastric cancer) were compared with 63 samples of primary gastric tumors located in the upper third of the stomach (primary gastric cancer) by both clinicopathologic and flow cytometric analysis. The depths of invasion of all these tu...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000227441
更新日期:1995-03-01 00:00:00
abstract::Thirty-five patients with metastatic breast cancer who had received one or two prior chemotherapeutic regimens were treated with elliptinium acetate at a dose of 80 mg/m2 for 3 days every 3 weeks. Of the 33 patients evaluable for response, 1 patient achieved complete remission, 4 achieved partial responses (15% overal...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000226797
更新日期:1990-01-01 00:00:00
abstract::In this study an attempt is made to propose a working clinical classification and staging of adult non-Hodgkin's lymphoma (NHL) which brings out both primary site and extent of disease. Unlike childhood NHL, where histopathology is uniformly of unfavourable type, this clinical staging system seems to have a prognostic...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000226843
更新日期:1990-01-01 00:00:00
abstract::Improved understanding of tumor biology has led to the identification of numerous growth factors that are involved in malignant transformation and tumor progression. Many of these factors induce cellular responses through receptors with intrinsic tyrosine kinase (TK) activity. Therefore, inhibiting receptor TK activit...
journal_title:Oncology
pub_type: 杂志文章,评审
doi:10.1159/000066198
更新日期:2002-01-01 00:00:00
abstract:PURPOSE:Preclinical studies indicated that imatinib may have single-agent activity in glioblastoma through inhibition of tyrosine kinase activity and also that it might enhance the efficacy of radiotherapy. We therefore sought to investigate clinical efficacy in patients with newly diagnosed and recurrent glioblastoma ...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000502483
更新日期:2020-01-01 00:00:00
abstract::While central ports are located at the chest, peripheral ports (PP) are inserted at the patients' forearms. Two new PPs (Healthport miniMax((R)) and Bard Titan Low Profile Port) and two well-established types (Port-A-Cath((R)) P.A.S. Port and PeriPort(TM) peripheral access system) were tested. 125 patients were given ...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000012059
更新日期:1999-11-01 00:00:00
abstract::The survival, and the patterns and mechanisms of failure of 41 patients with pure testicular seminoma treated at the Northern Israel Oncology Center from 1968 to 1983 were analyzed. The actuarial 5-year survival of all patients was 85.4% and of stage I patients, 92.2%. Treatment failures were analyzed. The following c...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000226341
更新日期:1986-01-01 00:00:00
abstract::The disease provoked by injections of water and other harmless liquids or wounds without tissue loss, is characterized by the regression of certain organs, opening in the epidermis, pigmentary anomalies and malignant tumors. The very few worms which recover spontaneously, regenerate the eliminated parts or develop sup...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000225055
更新日期:1975-01-01 00:00:00
abstract::An increase in serum iron levels and a decrease in serum unsaturated iron binding capacity (uIBC) were noted following the administration of cisplatinum to 9 children with malignancies. The mean serum iron concentration increased from a pretreatment level of 75.7 +/- 30.5 micrograms/ml to a posttreatment level of 162....
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000226657
更新日期:1988-01-01 00:00:00
abstract::Primary fetal rat fibroblasts (FRF cells) were transfected with DNA extracted from BKV-transformed hamster kidney cells at low passage after transformation (HKBKlp cells) and at high passage after transformation (HKBKhp cells). Two transformed rat cell lines were obtained, FRF-DNA-HKBKlp cells and FRF-DNA-HKBKhp cells...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000226404
更新日期:1986-01-01 00:00:00
abstract::Loss of heterozygosity (LOH) on chromosomes 13q, 16q and 17p has been associated with the progression of hepatocellular carcinoma (HCC). To investigate the prognostic impact of such LOH, we examined the metastasis-free survival of curatively resected HCC cases, in whom these LOHs were analyzed. Among the 49 HCC patien...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000048260
更新日期:2002-01-01 00:00:00
abstract::After exposure to the mutagen, ethylmethanesulfonate (EMS), or the carcinogen, urethane (UR), anchorage independence was observed in cultures derived from normal skin biopsies from patients with the heritable cancer syndrome, adenomatosis of the colon and rectum (ACR). Such colonies from methylcellulose suspension cul...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000225478
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:Recent data suggest that capecitabine may have little efficacy in women with metastatic triple negative breast cancer (TNT). We have therefore retrospectively analysed capecitabine outcome in the TN subgroup of patients with locally advanced or metastatic breast cancer treated in our unit. PATIENTS AND METH...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000323175
更新日期:2010-01-01 00:00:00
abstract::Twenty-two patients with metastatic breast carcinoma were treated with a combination of cisplatin (100 mg/m2 i.v. day 1) and etoposide (100 mg/m2 i.v. days 1-3). Eligible patients had measurable disease with normal organ functions, performance status < 3, age < 70 years and no previous chemotherapy for metastatic dise...
journal_title:Oncology
pub_type: 临床试验,杂志文章
doi:10.1159/000227364
更新日期:1994-07-01 00:00:00
abstract:BACKGROUND:In most guidelines, no other interventional therapy but liver transplantation is recommended for the treatment of hepatocellular carcinoma (HCC) with Child-Pugh C cirrhosis (CP-C). However, in Japan, patients were sometimes treated with expectation of benefit. SUMMARY:A workshop was conducted to explore the...
journal_title:Oncology
pub_type:
doi:10.1159/000368152
更新日期:2014-01-01 00:00:00
abstract::Of 352 patients with colorectal carcinoma followed for a minimum of 5 years after surgery, 39 cases (11.1%; median age 60 years) had mucinous adenocarcinoma, and 4 (1.1%; median age 62 years) had signet-ring cell carcinoma. Mucinous carcinomas were most frequently located in the rectum (61.5%) and in the sigmoid colon...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000227306
更新日期:1994-01-01 00:00:00
abstract::Magnetic resonance imaging-guided laser interstitial thermal therapy (LITT) is a minimally invasive treatment modality with recent increasing use to ablate brain tumors. When originally introduced in the late 1980s, the inability to precisely monitor and control the thermal ablation limited the adoption of LITT in neu...
journal_title:Oncology
pub_type: 杂志文章,评审
doi:10.1159/000362817
更新日期:2014-01-01 00:00:00
abstract::Between June 1980 and December 1984, 88 patients with stage III-IV ovarian carcinoma were entered in a study evaluating the role of debulking surgery and chemotherapy consisting of cyclophosphamide, doxorubicin, and cisplatin intravenously on day 1, every 4 weeks (CAP-1). The results after a median follow-up of 62 mon...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000226801
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:Pegylated liposomal doxorubicin (PLD) and capecitabine (CAP) have separately shown significant antitumor activity in a wide range of solid tumors. A phase I study was conducted in order to determine the maximum tolerated dose (MTD) and dose-limiting toxicities (DLTs) of their combination in patients with refr...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000090494
更新日期:2005-01-01 00:00:00
abstract::Three lung tumor-associated markers (LTAM), previously identified as a Cohn Fraction IV alpha-globulin (LTAM-1), ferritin (LTAM-2) and lactoferrin (LTAM-3) were separated by a combination of ion exchange, dye-affinity and molecular sieve chromatography. They were further purified by polyacrylamide gel electrophoresis ...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000225542
更新日期:1981-01-01 00:00:00
abstract:INTRODUCTION:Carcinoma of the biliary system is a rare tumor entity, and patients with advanced disease face a dismal prognosis. Because of the absence of standard chemotherapy for advanced biliary carcinoma, we have performed two consecutive studies to evaluate the clinical potential of 5-fluorouracil, leucovorin and ...
journal_title:Oncology
pub_type: 临床试验,杂志文章
doi:10.1159/000011961
更新日期:1999-04-01 00:00:00
abstract::We examined the expression of p16, the CDKN2A gene product, in EBV-associated gastric carcinomas (EBV-GCs). EBV-GCs were identified by detecting EBV-encoded small RNA (EBER) using an in situ hybridization assay of paraffin-embedded tissue. Two non-EBV-GC cases for each EBV-GC case were selected, matched for age, sex, ...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000080290
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVES:Low body mass index (BMI) and/or low lean body mass have been shown to be risk factors for chemotherapy-related toxicities in a number of different cancers. However, no data are available regarding the role of BMI as a risk factor for developing toxicities related to the novel anticancer agent, trabectedin, ...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000487266
更新日期:2018-01-01 00:00:00
abstract::During the period 1965-1980, 84 patients with Wilms' tumor, neuroblastoma and Ewing's sarcoma were treated at the University of Rochester Medical Center. All patients were evaluated for the presence of congenital abnormalities. Ten of 34 (29%) patients with Wilms' tumor, 3 of 32 (9%) patients with neuroblastoma, and 0...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000226064
更新日期:1985-01-01 00:00:00
abstract::Information technology (IT) can enhance or change many scenarios in cancer research for the better. In this paper, we introduce several examples, starting with clinical data reuse and collaboration including data sharing in research networks. Key challenges are semantic interoperability and data access (including data...
journal_title:Oncology
pub_type: 杂志文章,评审
doi:10.1159/000493638
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Postoperative management of patients with pancreatic adenocarcinoma (PA) is controversial. METHODS:The aim of this pilot study was to assess the feasibility of postoperative combination chemotherapy followed by radiotherapy in patients aged 18-70 years with a histological diagnosis of PA, and Karnofsky perf...
journal_title:Oncology
pub_type: 临床试验,杂志文章
doi:10.1159/000086780
更新日期:2005-01-01 00:00:00
abstract::67Ga-subtraction scan was found to be useful and a promising new method for the pre-treatment evaluation of the patient with Hodgkin's disease or non-Hodgkin's lymphoma. The scan appeared to be most accurate in the neck, chest, and axillary regions. It appears to offer a means of increasing the accuracy of evaluating ...
journal_title:Oncology
pub_type: 杂志文章
doi:10.1159/000225217
更新日期:1977-01-01 00:00:00