Signaling between tumor cells and the host bone marrow microenvironment.

abstract：:Mandibular first molars from 17-day-old mouse embryos were cultivated in vitro for 10 days using a new organ culture method. This method consisted of using a small glass dish and an agar chamber to slowly float the molars to the gas-medium interface where they were maintained by the surface tension of the medium. The ...

journal_title：Calcified tissue international

authors： Sakakura Y

更新日期：1986-10-01 00:00:00

abstract：:This article reviews the effects of restrictive eating disorders on bone health. The relationship between eating disorders and amenorrhea is discussed in detail. The pathologic impact of malnutrition on bone is explored by examining the results of studies using various available imaging techniques. The multiple hormon...

journal_title：Calcified tissue international

authors： Thornton D,Gordon CM

更新日期：2017-05-01 00:00:00

abstract：:Administration of active vitamin D sterols to treat secondary hyperparathyroidism in patients with chronic kidney disease receiving dialysis has been associated with elevated serum calcium and phosphorus levels, which may lead to increased risk of vascular calcification. However, calcimimetics, by binding to the parat...

journal_title：Calcified tissue international

authors： Shalhoub V,Shatzen E,Henley C,Boedigheimer M,McNinch J,Manoukian R,Damore M,Fitzpatrick D,Haas K,Twomey B,Kiaei P,Ward S,Lacey DL,Martin D

更新日期：2006-12-01 00:00:00

abstract：:Calcaneus bone mineral density (BMD) of 738 Japanese women (605 healthy and 133 with osteoporosis) was measured using single X-ray absorptiometry (SXA). A reference range of calcaneus BMD values for healthy Japanese women was established and the usefulness of this method for screening and diagnosis of osteoporosis was...

journal_title：Calcified tissue international

authors： Sekioka Y,Kushida K,Yamazaki K,Inoue T

更新日期：1999-08-01 00:00:00

abstract：:Effects of a single dose of 200 IU of nasal salmon calcitonin (SCT) on calcium metabolism and biochemical markers of bone turnover were investigated in 12 healthy male volunteers in a randomized, placebo-controlled, cross-over design. The nasal spray was given in the morning, and subsequently blood and urine samples w...

journal_title：Calcified tissue international

authors： Thamsborg G,Skousgaard SG,Daugaard H,Schifter S,Kollerup G,Sørensen OH

更新日期：1993-10-01 00:00:00

abstract：:Osteoarthritis (OA) is a chronic, debilitating disease affecting millions of people worldwide. Management of OA involves pharmacological and non-pharmacological approaches. Conventional pharmacological treatments have limited efficacy and are associated with a number of side-effects, restricting the number of patients...

journal_title：Calcified tissue international

authors： Ghouri A,Conaghan PG

更新日期：2020-02-13 00:00:00

abstract：:In the rat, prolonged administration of the luteinizing, hormone-releasing hormone agonist buserelin (25 micrograms/kg body wt/day s.c.) lowers blood estradiol, raises bone resorption, and induces osteopenia. The present study was undertaken to determine whether withdrawal of buserelin normalizes blood estradiol, slow...

journal_title：Calcified tissue international

authors： Goulding A,Gold E

更新日期：1990-01-01 00:00:00

abstract：:We studied the influence of age, gender, latitude, season, diet and ethnicity on plasma 25-hydroxyvitamin D 25 OHD, PTH, 1,25-dihydroxyvitamin D, vitamin D-binding protein, bone-specific alkaline phosphatase, and osteocalcin levels in 46 Greenlanders living in Nuuk (64 degrees N) on a traditional fare (group A), 45 Gr...

journal_title：Calcified tissue international

authors： Rejnmark L,Jørgensen ME,Pedersen MB,Hansen JC,Heickendorff L,Lauridsen AL,Mulvad G,Siggaard C,Skjoldborg H,Sørensen TB,Pedersen EB,Mosekilde L

更新日期：2004-03-01 00:00:00

abstract：:Periodic fringes corresponding to six different lattice planes have been observed in apatite crystals of human normal alveolar bone by transmission electron microscopy. Three of these sets of fringes have spacings less than 3.5 A corresponding to the Scherzer resolution of the microscope used. The (0002) lattice plane...

journal_title：Calcified tissue international

authors： Cuisinier F,Bres EF,Hemmerle J,Voegel JC,Frank RM

更新日期：1987-06-01 00:00:00

abstract：:Yerba mate (Ilex paraguariensis) is a xanthine-containing beverage, which is also rich in caffeine. Because caffeine has a negative impact on bone mineral density (BMD) mainly associated with low calcium (Ca) diets, there would be expected a negative effect of yerba mate on bone. In this study, Sprague-Dawley rats wer...

journal_title：Calcified tissue international

authors： Brun LR,Brance ML,Lombarte M,Maher MC,Di Loreto VE,Rigalli A

更新日期：2015-11-01 00:00:00

abstract：:Transcriptional regulation of the postnatal skeleton is incompletely understood. Here, we determined the consequence of loss of early growth response gene 1 (EGR-1) on bone properties. Analyses were performed on both the microscopic and molecular levels utilizing micro-computed tomography (micro-CT) and Fourier transf...

journal_title：Calcified tissue international

authors： Reumann MK,Strachna O,Lukashova L,Verdelis K,Donnelly E,Boskey AL,Mayer-Kuckuk P

更新日期：2011-07-01 00:00:00

abstract：:The effect of zinc on in vitro deoxyribonucleic acid (DNA) synthesis activity in the femoral-diaphyseal and metaphyseal tissues of newborn rats was investigated to determine a role of zinc in bone growth. In vitro DNA synthesis was assayed in a reaction mixture containing the 100 g centrifugation supernatant, which in...

journal_title：Calcified tissue international

authors： Ma ZJ,Yamaguchi M

更新日期：2001-09-01 00:00:00

abstract：:The ultimate hope of researchers and patients is a pathway to development of treatments for osteoarthritis to modify the disease process in addition to the symptoms. However, development of disease modifying drugs requires objective endpoints such as measures of joint structure, joint tissue homeostasis and/or joint s...

journal_title：Calcified tissue international

authors： Kraus VB,Karsdal MA

更新日期：2020-05-04 00:00:00

abstract：:Thyroxine (T4), triiodothyronine (T3), and alkaline phosphatase (AP) were assayed monthly in white-tailed deer plasma obtained from the antler (A), jugular (J), and the saphenous (S) veins during the period of antler growth and the period of mineralization. The concentrations of T3, T4, and AP in the J and S were not ...

journal_title：Calcified tissue international

authors： Bubenik GA,Sempere AJ,Hamr J

更新日期：1987-07-01 00:00:00

abstract：:We describe here the activity of a novel selective estrogen receptor modulator, SP500263. When given to adult ovariectomized (OVX) rats for 28 days at doses of 0.3, 1, or 3 mg/kg/day, we found that SP500263 partially protected against OVX-induced loss of bone mineral content in the distal ends of femurs and in the who...

journal_title：Calcified tissue international

authors： Sutherland MK,Brady H,Gayo-Fung LM,Leisten J,Lipps SG,McKie JA,O'Leary E,Patnaik N,Anderson DW,Bhagwat SS,Stein B

更新日期：2003-06-01 00:00:00

abstract：:The goal of this study was to find out if bone can recover after long-term administration of bisphosphonate. Disodium pamidronate (APD) was given orally by gavage to mature beagle dogs at doses of 0, 2.5, 12.5, and 25 mg/kg/day for 1 year (0.1% concentration) and the animals were allowed to recover for another year. A...

journal_title：Calcified tissue international

authors： Grynpas MD,Kasra M,Dumitriu M,Nespeca R,Very JM,Mertz BP

更新日期：1994-10-01 00:00:00

abstract：:Sarcopenia is now clinically defined as a loss of muscle mass coupled with functional deterioration (either walking speed or distance or grip strength). Based on the FRAX studies suggesting that the questions without bone mineral density can be used to screen for osteoporosis, there is now a valid simple questionnaire...

journal_title：Calcified tissue international

authors： Morley JE

更新日期：2016-04-01 00:00:00

abstract：:An organ culture system has been developed whereby mechanical stress can be applied to cranial sutures under controlled experimental conditions. The application of a continuous tensile mechanical stress (30 g) to cranial sutures from newborn rabbits (1--2 days) was accompanied by a significant increase in the incorpor...

journal_title：Calcified tissue international

authors： Meikle MC,Reynolds JJ,Sellers A,Dingle JT

更新日期：1979-10-31 00:00:00

abstract：:Osteoarthritis (OA), the most prevalent chronic joint disease, increases in prevalence with age, and affects majority of individuals over the age of 65 and is a leading musculoskeletal cause of impaired mobility in the elderly. Because the precise molecular mechanisms which are involved in the degradation of cartilage...

journal_title：Calcified tissue international

authors： Xia B,Di Chen,Zhang J,Hu S,Jin H,Tong P

更新日期：2014-12-01 00:00:00

abstract：:The development of prophylaxes and treatments of bone diseases that can effectively increase the strength of bone as a structure necessitates a better understanding of the time course by which chemical properties define the stiffness of the material during primary and secondary mineralization. It was hypothesized that...

journal_title：Calcified tissue international

authors： Busa B,Miller LM,Rubin CT,Qin YX,Judex S

更新日期：2005-12-01 00:00:00

abstract：:The current study is based on our earlier investigation carried out in 1999, where bone mineral density (BMD) of 35 neurofibromatosis type 1 (NF1) patients was measured and osteoporosis was shown to be common in NF1. The findings have been confirmed by a number of later publications. The purpose of the current longitu...

journal_title：Calcified tissue international

authors： Heervä E,Leinonen P,Kuorilehto T,Peltonen S,Pöyhönen M,Väänänen K,Peltonen J

更新日期：2013-01-01 00:00:00

abstract：:Bone involvement is one of the most disabling aspects of type I Gaucher disease and its pathophysiology is still not well understood. As an invasive procedure, bone biopsies are not appropriate in a large population study. The development of sensitive bone resorption and formation tests have allowed the authors to stu...

journal_title：Calcified tissue international

authors： Ciana G,Martini C,Leopaldi A,Tamaro G,Katouzian F,Ronfani L,Bembi B

更新日期：2003-03-01 00:00:00

abstract：:We studied the epidemiology of osteoporotic fractures of the proximal femur (cervical and trochanteric fractures) in residents of Barcelona, aged 45 years or over, for a 1-year period. Fractures resulting from metastases were not included. During the period of observation, a total of 1,358 patients with hip fractures ...

journal_title：Calcified tissue international

authors： Diez A,Puig J,Martinez MT,Diez JL,Aubia J,Vivancos J

更新日期：1989-06-01 00:00:00

abstract：:Observational studies examining associations of smoking and alcohol consumption with bone mineral density (BMD) have generated inconsistent results and suffer from several methodological limitations. We aim to evaluate whether there are causal associations between smoking, alcohol consumption, and BMD using a Mendelia...

journal_title：Calcified tissue international

authors： Guo R,Wu L,Fu Q

更新日期：2018-11-01 00:00:00

abstract：:Crouzon syndrome is a debilitating congenital disorder involving abnormal craniofacial skeletal development caused by mutations in fibroblast growth factor receptor-2 (FGFR2). Phenotypic expression in humans exhibits an autosomal dominant pattern that commonly involves premature fusion of the coronal suture (craniosyn...

journal_title：Calcified tissue international

authors： Liu J,Nam HK,Wang E,Hatch NE

更新日期：2013-05-01 00:00:00

abstract：:The orientation of nanoscale mineral platelets was quantitatively evaluated in relation to the shape of lacunae associated with partially embedded osteocytes (osteoblastic-osteocytes) on the surface of deproteinised trabecular bone of adult sheep. By scanning electron microscopy and image analysis, the mean orientatio...

journal_title：Calcified tissue international

authors： Shah FA,Zanghellini E,Matic A,Thomsen P,Palmquist A

更新日期：2016-02-01 00:00:00

abstract：:Treatment of large bone defects (LBDs) is technically demanding. Tissue engineering is an option. A bioactive graft may be produced by combining tissue scaffolds and healing promotive factors in order to accelerate bone repair. We investigated the role of Simvastatin (Sim)-embedded porous Gelapin (Gel) scaffold on exp...

journal_title：Calcified tissue international

authors： Moshiri A,Shahrezaee M,Shekarchi B,Oryan A,Azma K

更新日期：2015-06-01 00:00:00

abstract：:Experimental analysis with paired femurs provides the opportunity to study within-person differences in fracture type and associated structural side differences. We hypothesized that different fracture types in the hips of a subject are associated with structural asymmetry. Bone mineral density (BMD) and structural me...

journal_title：Calcified tissue international

authors： Thevenot J,Pulkkinen P,Kuhn V,Eckstein F,Jämsä T

更新日期：2010-09-01 00:00:00

abstract：:The effects of the trace metals zinc (Zn), manganese (Mn), and cadmium (Cd) on the metabolism of growth plate chondrocytes was examined using a mineralizing culture system. Supplementation of serum-free primary cultures of growth plate chondrocytes with 10-100 mu m Zn resulted in an increase in cell protein and greatl...

journal_title：Calcified tissue international

authors： Litchfield TM,Ishikawa Y,Wu LN,Wuthier RE,Sauer GR

更新日期：1998-04-01 00:00:00

abstract：:Abnormal PTH secretion and cell growth in hyperparathyroid tissues are accompanied with reduced expression of Ca2+-sensing receptor (CaR) which plays a key role in Ca-regulated PTH release. In this study, we examined the receptor expression in parathyroid adenomas using specific anti-CaR antibody and investigated rela...

journal_title：Calcified tissue international

authors： Kaneko C,Mizunashi K,Tanaka M,Uzuki M,Kikuchi M,Sawai T,Goto MM

更新日期：1999-03-01 00:00:00