Osteoarthritis: Current Molecular Biomarkers and the Way Forward.

abstract：:Undesirable changes in health-related parameters are thought to occur in retiring female athletes, but this has not been examined in longitudinal studies. The purpose of this study was to examine longitudinal changes in bone mineral density (BMD), body composition, and dietary intake in gymnasts and controls. Nonathle...

journal_title：Calcified tissue international

authors： Kudlac J,Nichols DL,Sanborn CF,DiMarco NM

更新日期：2004-12-01 00:00:00

abstract：:The goals of internal fixation are an accurate reduction and stable fixation in the presence of adequate bony vascularity. This can be achieved by a variety of means including plate fixation. A certain amount of periosteal stripping is necessary for proper open reduction of a fracture and for proper plate application....

journal_title：Calcified tissue international

authors： Kowalski MJ,Schemitsch EH,Kregor PJ,Senft D,Swiontkowski MF

更新日期：1996-07-01 00:00:00

abstract：:Extracellular ATP, and to a lesser extent adenosine, an ATP metabolite, stimulated cell proliferation in osteoblast-like cells (MC3T3-E1). ATP increased cytosolic Ca2+ due to Ca2+ mobilization from intracellular storage in the same concentration range of the nucleotide as that effective for DNA synthesis, suggesting t...

journal_title：Calcified tissue international

authors： Shimegi S

更新日期：1996-02-01 00:00:00

abstract：:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA levels are commonly used as an internal control to normalize gene expression data based on the belief that this gene is constitutively expressed. However, GAPDH mRNA levels increased by more than 2.5-fold in tibiae of hindlimb unloaded female rats compared to L32 m...

journal_title：Calcified tissue international

authors： Maran A,Hefferan TE,Zhang M,Turner RT

更新日期：2004-02-01 00:00:00

abstract：:The current study is based on our earlier investigation carried out in 1999, where bone mineral density (BMD) of 35 neurofibromatosis type 1 (NF1) patients was measured and osteoporosis was shown to be common in NF1. The findings have been confirmed by a number of later publications. The purpose of the current longitu...

journal_title：Calcified tissue international

authors： Heervä E,Leinonen P,Kuorilehto T,Peltonen S,Pöyhönen M,Väänänen K,Peltonen J

更新日期：2013-01-01 00:00:00

abstract：:Results of previous studies suggest that children and adolescents with osteogenesis imperfecta (OI) type IV have muscle force deficits. However, muscle function remains to be objectively quantified in this population. This study aimed to assess upper and lower extremity muscle function in patients with OI type IV. It ...

journal_title：Calcified tissue international

authors： Veilleux LN,Darsaklis VB,Montpetit K,Glorieux FH,Rauch F

更新日期：2017-10-01 00:00:00

abstract：:Ipriflavone (i.p.) positively affects bone density in postmenopausal osteoporosis, primarily by inhibiting bone resorption. Using in vitro models of human osteoblast differentiation, we have observed that i.p. and some of its metabolites stimulate the expression of bone sialoprotein, decorin, and type I collagen, and ...

journal_title：Calcified tissue international

authors： Civitelli R

更新日期：1997-01-01 00:00:00

abstract：:Cross-sectional and case-control studies are efficient and inexpensive approaches to the study of osteoporosis; their validity depends primarily on how the subjects are sampled. Retrospective studies of fractures may be biased if measurements change as a result of the fracture. Prospective cohort studies are less pron...

journal_title：Calcified tissue international

authors： Cummings SR

更新日期：1991-01-01 00:00:00

abstract：:The purpose of this study was to use the concept of metastable equilibrium solubility (MES) to describe the anomalous solubility behavior of carbonated apatite (CAP) in the presence of solution strontium. A CAP sample (4.8 wt% CO(3), synthesized at 70 degrees C) was prepared by precipitation. Baseline MES distribution...

journal_title：Calcified tissue international

authors： Heslop DD,Bi Y,Baig AA,Higuchi WI

更新日期：2004-01-01 00:00:00

abstract：:The aim of this study was to follow the changes in bone mineral density (BMD) and biochemical markers of bone turnover in 10 children (7.5-17.5 years of age) with severe juvenile idiopathic arthritis (JIA), during a 3-year therapy with salmon calcitonin (100 IU/day 2 months on and 2 off for a year and 200 IU/day for 2...

journal_title：Calcified tissue international

authors： Siamopoulou A,Challa A,Kapoglou P,Cholevas V,Mavridis AK,Lapatsanis PD

更新日期：2001-07-01 00:00:00

abstract：:The purpose of the present study was to determine if the type of dietary fat can modify the fatty acid composition and arachidonic acid levels in the alveolar bone phospholipids. Three groups of rats were fed nutritionally adequate semipurified diets containing different lipids: 10% corn oil (control, group I, rich in...

journal_title：Calcified tissue international

authors： Alam SQ,Kokkinos PP,Alam BS

更新日期：1993-11-01 00:00:00

abstract：:We have recently reported that soy isoflavones particularly when provided in the context of soy protein are capable of preventing loss of bone mineral density due to orchidectomy in F344 rats. We hypothesize, that soy isoflavones also exert beneficial effects on bone microstructural properties, in part, by enhancing b...

journal_title：Calcified tissue international

authors： Soung DY,Devareddy L,Khalil DA,Hooshmand S,Patade A,Lucas EA,Arjmandi BH

更新日期：2006-06-01 00:00:00

abstract：:Prosected vertebrae and phalanges from 32 cadavera were examined using noninvasive methods commonly used for assessment of osteoporosis. Bone measures were then compared with a strength variable obtained by mechanically crushing or breaking the bones. All of the phalangeal density assessment techniques were found to b...

journal_title：Calcified tissue international

authors： Oyster N,Smith FW

更新日期：1988-08-01 00:00:00

abstract：:Non-steroidal anti-inflammatory drugs (NSAID) have been recommended to prevent of heterotopic ossification (HO) after total hip arthroplasty (THA), but debates are still ongoing. The present Bayesian network meta-analysis of randomized clinical trials (RCTs) compared all available pathways of NSAID treatment as prophy...

journal_title：Calcified tissue international

authors： Migliorini F,Trivellas A,Eschweiler J,Driessen A,Tingart M,Maffulli N

更新日期：2021-02-01 00:00:00

abstract：:The aim of this study was to evaluate bone resorption (BR) in rats by two methods: chronic 3H-tetracycline labeling (3HTC) and pyridinium crosslink excretion (PYDX), and compare the sensitivity of these markers in two age groups. Female Sprague-Dawley rats at 12-29 weeks of age ("mature", n = 12) and at 40-57 weeks of...

journal_title：Calcified tissue international

authors： Talbott SM,Chowdhury H,Shapses SA

更新日期：1999-04-01 00:00:00

abstract：:Vitamin D has long been known to be important for bone health, but there is currently no consensus on the amount of vitamin D needed or how it varies with age, race/ethnicity, body size, absorption efficiency, season, and other factors. This review describes the effects of vitamin D on calcium absorption, parathyroid ...

journal_title：Calcified tissue international

authors： Dawson-Hughes B

更新日期：2013-02-01 00:00:00

abstract：:The bone mineral status of 17 girls with Turner's syndrome was evaluated by single photon absorptiometry. Bone mineral content (BMC) was 25.4% below that predicted by normalization for age, sex, height, weight, and bone width. Only 25% of this demineralization could be attributed to delayed skeletal maturation. Bones ...

journal_title：Calcified tissue international

authors： Shore RM,Chesney RW,Mazess RB,Rose PG,Bargman GJ

更新日期：1982-01-01 00:00:00

abstract：:It is our hypothesis that interstitial fluid flow plays a role in the bone remodeling response to mechanical loading. The fluid flow-induced expression of three proteins (collagen, osteopontin, and alkaline phosphatase) involved in bone remodeling was investigated. Rat calvarial osteoblasts subjected to pulsatile flui...

journal_title：Calcified tissue international

authors： Hillsley MV,Frangos JA

更新日期：1997-01-01 00:00:00

abstract：:To assess whether vertebral fractures are associated with osteopenia in chronic alcoholic patients, a transversal study was carried out in 76 chronic alcoholic males and 62 age-matched healthy males. Lumbar bone mineral density (BMD) by dual photon absorptiometry and spinal chest X-ray films were done in all patients....

journal_title：Calcified tissue international

authors： Peris P,Guañabens N,Parés A,Pons F,del Rio L,Monegal A,Surís X,Caballería J,Rodés J,Muñoz-Gómez J

更新日期：1995-08-01 00:00:00

abstract：:Osteoclastic bone resorption can be induced within the auditory bulla of the Mongolian gerbil by minute increases in air pressure. The objective of this study was to determine the rate at which osteoclasts are induced in areas of resorption and to compare the rate of osteoblast recruitment. Stainless steel tubes were ...

journal_title：Calcified tissue international

authors： Chole RA,Chan DE

更新日期：1989-11-01 00:00:00

abstract：:The existence of nutritional deficiency rickets among infants in sunny Riyadh was confirmed radiologically. Most of the rachitic infants were breast-fed, some received unsupplemented infant feeding formulae, and all live in an environment that is devoid of sunlight. Their mean age at the time of onset was 10.5 months....

journal_title：Calcified tissue international

authors： Elidrissy AT,Sedrani SH,Lawson DE

更新日期：1984-05-01 00:00:00

abstract：:We describe here the activity of a novel selective estrogen receptor modulator, SP500263. When given to adult ovariectomized (OVX) rats for 28 days at doses of 0.3, 1, or 3 mg/kg/day, we found that SP500263 partially protected against OVX-induced loss of bone mineral content in the distal ends of femurs and in the who...

journal_title：Calcified tissue international

authors： Sutherland MK,Brady H,Gayo-Fung LM,Leisten J,Lipps SG,McKie JA,O'Leary E,Patnaik N,Anderson DW,Bhagwat SS,Stein B

更新日期：2003-06-01 00:00:00

abstract：:Lumbar spine bone mass and density were measured with Dual photon absorptiometry (DPA) in 60 patients with crush fractures and 60 age-matched normal women. Short-term reproducibility of bone mineral density (BMD) was 1.3% in normal women and 2.5% in osteoporotic women; long-term reproducibility in normal women was 2.2...

journal_title：Calcified tissue international

authors： Pouilles JM,Tremollieres F,Louvet JP,Fournie B,Morlock G,Ribot C

更新日期：1988-12-01 00:00:00

abstract：:Polymorphisms in the region of the gene for the vitamin D receptor (VDR) (chromosome 12q12-14) have been associated with differences in bone mineral density (BMD) in some studies but not in others. Because linkage analysis assesses allele sharing identical-by-descent among relatives instead of the association of a par...

journal_title：Calcified tissue international

authors： Zee RY,Myers RH,Hannan MT,Wilson PW,Ordovas JM,Schaefer EJ,Lindpaintner K,Kiel DP

更新日期：2000-12-01 00:00:00

abstract：:Little is known about hypoxia-induced modification of the canal network in the cortical bone despite its involvement in intracortical vascularity and bone blood supply. In this study, we examined the effect of chronic hypoxia on the canal network in postnatal bone. Tibiae were harvested from 4- and 8-week-old rats (hy...

journal_title：Calcified tissue international

authors： Matsumoto T,Ando N,Tomii T,Uesugi K

更新日期：2011-01-01 00:00:00

abstract：:Thyroxine (T4), triiodothyronine (T3), and alkaline phosphatase (AP) were assayed monthly in white-tailed deer plasma obtained from the antler (A), jugular (J), and the saphenous (S) veins during the period of antler growth and the period of mineralization. The concentrations of T3, T4, and AP in the J and S were not ...

journal_title：Calcified tissue international

authors： Bubenik GA,Sempere AJ,Hamr J

更新日期：1987-07-01 00:00:00

abstract：:A simple method for determining histamine and polyamines in various tissues was devised. The method, however, could not be applied to calcified tissues, because the high concentration of Ca2+ in the extract interferes with the chromatographic separation of these amines. By treating the extracts from calcified tissues ...

journal_title：Calcified tissue international

authors： Endo Y,Kikuchi T,Nakamura M,Shinoda H

更新日期：1992-07-01 00:00:00

abstract：:Studies suggest that long-term use of proton pump inhibitors (PPIs) may be associated with an increased risk of fracture. However, the role of medication adherence in this association is not fully understood. A retrospective cohort study was conducted to examine the relationship between PPI use/adherence and fracture ...

journal_title：Calcified tissue international

authors： Ding J,Heller DA,Ahern FM,Brown TV

更新日期：2014-06-01 00:00:00

abstract：:Several studies have demonstrated that bone has the power of regeneration and repair. BMPs (bone morphogenetic proteins) are involved in the determination of osteoblast phenotype and bone turnover, therefore genes coding for these proteins, like BMP-4, could be considered potential candidate genes for osteoporosis. We...

journal_title：Calcified tissue international

authors： Semprini S,Mango R,Brancati F,Dallapiccola B,Becherini L,Novelli G,De Lorenzo A,Brandi ML,Gennari L

更新日期：2000-07-01 00:00:00

abstract：:Enhanced osteoclast formation and function is a fundamental cause of alterations to bone structure and plays an important role in several diseases impairing bone quality. Recent work revealed that TRP calcium channels 3 and 6 might play a special role in this context. By analyzing the bone phenotype of TRPC6-deficient...

journal_title：Calcified tissue international

authors： Klein S,Mentrup B,Timmen M,Sherwood J,Lindemann O,Fobker M,Kronenberg D,Pap T,Raschke MJ,Stange R

更新日期：2020-06-01 00:00:00