Fifty-percent partial liver transplantation in the rat.

abstract：:We reviewed the results of all percutaneous fine needle aspirations (FNA) and open lung biopsies (OLB) after bone marrow transplantation at our center (1984-1987) for the evaluation of focal lung lesions that developed or persisted despite antibiotic administration. We sought to determine the prevalence and types of i...

journal_title：Transplantation

authors： Crawford SW,Hackman RC,Clark JG

更新日期：1989-08-01 00:00:00

abstract：:Natural suppressor (NS) activity is detected in tissues undergoing intense hematopoietic regeneration. This includes the spleens of mice recovering from total lymphoid irradiation or cyclophosphamide treatment, or after induction of chronic graft-versus-host disease against minor histocompatibility antigens. NS cells ...

journal_title：Transplantation

authors： Schreiber KL,Forman J

更新日期：1993-09-01 00:00:00

abstract：:Since chemotaxis is an important mechanism by which leukocytes are recruited to allografts during rejection, the effect of immunosuppressant agents on in vitro chemotactic responses of neutrophils, monocytes, and lymphocytes was studied. Cyclosporine caused profound inhibition of lymphocyte chemotaxis to three differe...

journal_title：Transplantation

authors： Adams DH,Wang LF,Neuberger JM,Elias E

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Live kidney donation is safe for healthy donors and an effective treatment for patients with end-stage renal disease. Many potential donors are referred for live kidney donation, but only a small percentage donate. This study aims to determine reasons for nondonation and establish if racial differences exist...

journal_title：Transplantation

authors： Lunsford SL,Simpson KS,Chavin KD,Menching KJ,Miles LG,Shilling LM,Smalls GR,Baliga PK

更新日期：2006-10-15 00:00:00

abstract：:Incompatibility for DBA/2 (D2) minor histocompatibility antigens (MiHA) alone leads to a severe lethal graft-versus-host reaction (GVHR) in irradiated (D2 X B10.D2)F1 mice receiving a bone-marrow-plus-spleen-cell graft from B10.D2 donors. This mortality is abrogated when the donors are preimmunized simultaneously agai...

journal_title：Transplantation

authors： Pritchard LL,Halle-Pannenko O

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Thymoglobulin given before allo-hematopoietic stem-cell transplantation (HSCT) from unrelated donors reduces acute graft-versus-host disease (GvHD), but the optimal dose is unknown. METHOD:Four different doses of Thymoglobulin were given to 162 patients with hematologic malignancies undergoing unrelated don...

journal_title：Transplantation

authors： Remberger M,Svahn BM,Mattsson J,Ringdén O

更新日期：2004-07-15 00:00:00

abstract：BACKGROUND:Recently, peptides derived from the heavy chain of HLA-B2702 have been shown to modulate immune responses. In this study, we examined the use of these peptides for immunosuppression in a pig to mouse islet xenograft model. METHODS:Purified porcine islets were transplanted in autoimmune (non-obese diabetic) ...

journal_title：Transplantation

authors： Squiers EC,Hodell M,Tice D,Buelow R

更新日期：1998-12-15 00:00:00

abstract：BACKGROUND:In kidney transplantation, dynamic prediction of patient and kidney graft survival (DynPG) may help to promote therapeutic alliance by delivering personalized evidence-based information about long-term graft survival for kidney transplant recipients. The objective of the current study is to externally valida...

journal_title：Transplantation

authors： Lenain R,Dantan E,Giral M,Foucher Y,Asar Ö,Naesens M,Hazzan M,Fournier MC

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:This study analyzes the biochemical, serological, and virological efficacy and the safety of adefovir dipivoxil in patients with renal disturbances. METHODS:Twelve patients with lamivudine-resistant hepatitis B virus (HBV) chronic infection were treated for a median time of 15 (3-19) months. The daily dosag...

journal_title：Transplantation

authors： Fontaine H,Vallet-Pichard A,Chaix ML,Currie G,Serpaggi J,Verkarre V,Varaut A,Morales E,Nalpas B,Brosgart C,Pol S

更新日期：2005-10-27 00:00:00

abstract：BACKGROUND:The pig is currently considered to be the most likely candidate for a xenogenic-organ source. Anti-pig human T-cell response via co-stimulatory molecules has been studied with great interest. The soluble form of porcine CD80 has recently been cloned and characterized, but the sequence of the transmembrane fo...

journal_title：Transplantation

authors： Wada M,Amae S,Sasaki H,Ishii T,Sano N,Nio M,Hayashi Y,Ohi R

更新日期：2003-06-15 00:00:00

abstract：BACKGROUND:Preemptive kidney transplantation (prior to the institution of dialysis) avoids the morbidity and mortality of dialysis; however, detailed studies of high-risk patients are lacking. The aim of the current study was to compare recent outcomes of preemptive (P) versus nonpreemptive (NP) living donor kidney tra...

journal_title：Transplantation

authors： Innocenti GR,Wadei HM,Prieto M,Dean PG,Ramos EJ,Textor S,Khamash H,Larson TS,Cosio F,Kosberg K,Fix L,Bauer C,Stegall MD

更新日期：2007-01-27 00:00:00

abstract：BACKGROUND:Human leukocyte antigen (HLA) antibodies produced after transplantation are frequently measured in transplant recipients, because they are strongly associated with humoral rejection and graft loss. However, antibodies can be induced by posttransplant blood transfusions rather than by the graft, casting doubt...

journal_title：Transplantation

authors： Scornik JC,Schold JD,Bucci M,Meier-Kriesche HU

更新日期：2009-05-15 00:00:00

abstract：:The interactions of rapamycin (Rapa), CsA, and donor-specific transfusion (DST) were examined in an ACI to Lewis rat heterotopic cardiac allograft model. Survival data were truncated at 175 days for the purpose of statistical comparisons. Vehicle (Veh)-treated animals rejected at a mean of 7.3 +/- 0.2 days. Treatment ...

journal_title：Transplantation

authors： Davies CB,Madden RL,Alexander JW,Cofer BR,Fisher RA,Anderson P

更新日期：1993-05-01 00:00:00

abstract：:Since 1989, the U.S. Food and Drug Administration (FDA) has encouraged the study of new drug and therapeutic products in elderly patients. However, despite the aging population in the United States, elderly patients continue to be underrepresented in clinical trials across a variety of therapeutic areas, including tra...

journal_title：Transplantation

authors： Meyer JM,Archdeacon P,Albrecht R

更新日期：2013-04-15 00:00:00

abstract：BACKGROUND:The consequences of a prior human herpesvirus-8 (HHV-8) infection in kidney-transplant recipients are still partially unknown. The aim of this monocentric study was to determine the prevalence of HHV-8-seropositive patients at the time of transplantation and to identify the main clinical events of these HHV-...

journal_title：Transplantation

authors： Francès C,Mouquet C,Marcelin AG,Barete S,Agher R,Charron D,Benalia H,Dupin N,Piette JC,Bitker MO,Calvez V

更新日期：2000-05-15 00:00:00

abstract：:Prospective clinical trials are constructed with high levels of internal validity. Sample size and power considerations usually address primary endpoints. Primary endpoints have traditionally included events that are becoming increasingly less common and thus have led to growing use of composite endpoints and noninfer...

journal_title：Transplantation

authors： Srinivas TR,Ho B,Kang J,Kaplan B

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Gastrointestinal complications are common in patients after lung and heart transplantation. Endoscopy is a standard method for the assessment of gastrointestinal morbidities. The aim of this study was to analyze the number and type of complications during endoscopic procedures in patients before and after lu...

journal_title：Transplantation

authors： Lenzen H,Cieplik N,Elkharsawi AR,Negm AA,Avsar M,Bara CL,Gottlieb J,Manns MP,Lankisch TO

更新日期：2015-07-01 00:00:00

abstract：:A portable hypothermic perfusion system for storage of hearts has been developed. The system uses the airlift pump principle, whereby the flow of gas maintains circulation of the perfusate through the heart; no other energy source is required. Performance on ex vivo functional testing of 10 pig hearts stored for 20 to...

journal_title：Transplantation

authors： Wicomb WN,Cooper DK,Barnard CN

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:NKp46 expression in natural killer (NK) cells has recently been shown to affect the responsiveness to antiviral treatment in hepatitis C virus (HCV)-infected patients. However, the density of NKp46 on intrahepatic NK cells is remarkably higher than that on peripherally circulating NK cells, whereas the bioph...

journal_title：Transplantation

authors： Tanimine N,Tanaka Y,Abe T,Piao J,Chayama K,Ohdan H

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The short tolerable cold ischemia time and the importance of other risk factors have generally superseded the role of HLA matching in the allocation of donor hearts. Recent advances in the accuracy and time required to perform HLA typing and crossmatching, however, have led us to re-examine the United Networ...

journal_title：Transplantation

authors： Thompson JS,Thacker LR 2nd,Takemoto S

更新日期：2000-05-27 00:00:00

abstract：:The success of kidney transplants is limited by the lack of robust improvements in long-term survival. It is now recognized that alloimmune responses are responsible for the majority of allograft failures. Development of novel therapies to decrease allosensitization is critical. The lack of new drug development in kid...

journal_title：Transplantation

authors： Jordan SC,Choi J,Kim I,Wu G,Toyoda M,Shin B,Vo A

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Bioluminescence imaging (BLI) modalities are being developed to monitor islet transplant mass and function in vivo. The aim of this study was to use the BLI system to determine how the change in functional islet mass correlated to metabolic abnormalities during the course of alloimmune rejection in a murine ...

journal_title：Transplantation

authors： Chen X,Zhang X,Larson CS,Baker MS,Kaufman DB

更新日期：2006-05-27 00:00:00

abstract：:Glucocorticoids (GC) inhibit IL-2 gene transcription by interfering with the binding of the nuclear factor activator protein-1 on the IL-2 promoter. Calcineurin, a Ca2+/calmodulin-dependent protein phosphatase, is an essential component of the T cell antigen receptor signal transduction pathway leading to IL-2 gene tr...

journal_title：Transplantation

authors： Paliogianni F,Boumpas DT

更新日期：1995-05-15 00:00:00

abstract：BACKGROUND:Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is a distinct form of glomerulonephritis that often recurs after kidney transplantation causing severe graft injury and often failure. METHODS:We describe post transplant outcomes and response to therapy in 20 recipients with ...

journal_title：Transplantation

authors： Buxeda A,Said SM,Nasr SH,Leung N,El Ters M,Cosio FG

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:New-onset diabetes is common after kidney transplantation, but the benefit of lifestyle intervention to improve glucose metabolism posttransplantation is unproven. METHODS:We conducted a single-center, randomized controlled trial involving 130 nondiabetic kidney transplant recipients with stable function be...

journal_title：Transplantation

authors： Kuningas K,Driscoll J,Mair R,Smith H,Dutton M,Day E,Sharif AA

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Fatty livers are more prone to primary nonfunction after transplantation. It is known that cell injury is strongly associated with alterations in the content and composition of membrane lipids. We assumed that plasma membrane (PM) fluidity, which is the most important property of the membrane, differed betwe...

journal_title：Transplantation

authors： Fukumori T,Ohkohchi N,Tsukamoto S,Satomi S

更新日期：1999-01-27 00:00:00

abstract：:The combination of pharmacokinetic and pharmacodynamic (measurement of the biological effect) monitoring of immunosuppressive drugs provides a method for the optimization of drug dosing. We chose to investigate this using mycophenolic acid (MPA), an immunosuppressive drug that mediates its effect by the inhibition of ...

journal_title：Transplantation

authors： Langman LJ,Shapiro AM,Lakey JR,LeGatt DF,Kneteman NM,Yatscoff RW

更新日期：1996-01-15 00:00:00

abstract：:Hemorrhagic cystitis is a well known complication of allogeneic bone marrow transplantation (BMT) and is normally attributed to the use of high-dose cyclophosphamide in the preparative regimen. Hemorrhagic cystitis occurring late after BMT is unlikely to be due to the effects of this conditioning, and probably has an ...

journal_title：Transplantation

authors： Apperley JF,Rice SJ,Bishop JA,Chia YC,Krausz T,Gardner SD,Goldman JM

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:End-stage renal disease (ESRD) is an increasing problem in patients infected with the human immunodeficiency virus (HIV). The use of highly active antiretroviral therapy (HAART) has decreased the morbidity associated with HIV and has prompted renewed interest in renal transplantation. METHODS:We performed f...

journal_title：Transplantation

authors： Tan HP,Kaczorowski DJ,Basu A,Khan A,McCauley J,Marcos A,Fung JJ,Starzl TE,Shapiro R

更新日期：2004-12-15 00:00:00

abstract：:The length of time after syngeneic bone marrow reconstitution when tolerance to alloantigens can be induced in adult mice during T cell differentiation from bone marrow cells was studied by exposing those T cells to (recipient x donor)F1 spleen cells. Supralethally irradiated C3H/He Slc(C3H; H-2k) mice were reconstitu...

journal_title：Transplantation

authors： Tomita Y,Himeno K,Mayumi H,Tokuda N,Nomoto K

更新日期：1989-06-01 00:00:00