Renal transplantation without sutures using the vascular clipping system for renal artery and vein anastomosis--a new technique.

abstract：:We describe a patient transfused with 200 ml of donor fresh whole blood three times at 2-week intervals. Three weeks after the last transfusion, transplantation and splenectomy were done at the same time. Splenic cells from this DST pretreated patient were fused with murine myeloma cells (X63-Ag8, 653). With DST pretr...

journal_title：Transplantation

authors： Kawamura T,Sakagami K,Haisa M,Morisaki F,Takasu S,Inagaki M,Oiwa T,Orita K

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Solid organ xenograft rejection is associated with vascular injury resulting at least in part in platelet activation, and rejected xenografts invariably demonstrate intravascular thrombosis and interstitial hemorrhage. Complement activation plays a prominent role in platelet-endothelial interaction. We teste...

journal_title：Transplantation

authors： Brandl U,Jöckle H,Erhardt M,Michel S,Burdorf L,Brenner P,Bittmann I,Rössle M,Mordstein V,Hammer C,Thein E,Reichart B,Schmoeckel M

更新日期：2007-12-27 00:00:00

abstract：:Prominent components of vascularized xenograft rejection such as platelet activation and microvascular thrombosis may be dependent upon thrombin generation in vivo. To study potential therapeutic benefits of a synthetic low-molecular-weight thrombin inhibitor, SDZ MTH 958, in hyperacute porcine heart rejection by huma...

journal_title：Transplantation

authors： Robson SC,Young VK,Cook NS,Metternich R,Kasper-Konig W,Lesnikoski BA,Pierson RN 3rd,Hancock WW,Candinas D,White DJ,Bach FH

更新日期：1996-03-27 00:00:00

abstract：:Donor-specific blood transfusion (DSBT) in animals and humans can either promote subsequent renal graft survival or lead to sensitization and graft rejection. Using a rat renal allograft model, we have examined whether the effects of DSBT on renal allograft outcome and IgG alloantibody responses are linked to the host...

journal_title：Transplantation

authors： Wasowska B,Baldwin WM 3rd,Howell DN,Sanfilippo F

更新日期：1993-09-01 00:00:00

abstract：:Murine lymphoid cells sensitized against allografts express two types of cytotoxicity measured in vitro in short-term assays of 2 to 3 hr by 51Cr release. One type of cytotoxicity is specific against target cells carrying the sensitizing alloantigens, and the other type is nonspecific against both syngeneic and unrela...

journal_title：Transplantation

authors： Bonavida B,Bradley TP

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:The established method of pretransplant cross-matching does not detect IgA antibodies, and IgA antibodies have thus been ignored when assessing patients for transplantation. The aim of this study was to detect IgA allo- and autoreactive antibodies using flow cytometry and to correlate the results with transp...

journal_title：Transplantation

authors： Doran TJ,Süsal C,Opelz G,Geczy AF

更新日期：1999-01-27 00:00:00

abstract：BACKGROUND:Little is known about innate lymphoid cell (ILC) populations in the human gut, and the turnover of these cells and their subsets after transplantation has not been described. METHODS:Intestinal samples were taken from 4 isolated intestine and 3 multivisceral transplant recipients at the time of any operativ...

journal_title：Transplantation

authors： Weiner J,Zuber J,Shonts B,Yang S,Fu J,Martinez M,Farber DL,Kato T,Sykes M

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Infections are a major cause of morbidity and mortality in kidney allograft recipients. In this post hoc analysis of a randomized clinical trial which tested the effect of denosumab on bone mineral density, we assessed the impact of this drug on the incidence and severity of infections in the first year afte...

journal_title：Transplantation

authors： Bonani M,Frey D,de Rougemont O,Mueller NJ,Mueller TF,Graf N,Wüthrich RP

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Recurrent hepatitis C virus (HCV) after liver transplantation (OLT) is a major cause of graft loss in HCV-positive patients. In this study, we evaluated the efficacy and safety of pegylated interferon alfa-2b (peginterferon) and ribavirin treatment for recurrent HCV after OLT and analyzed the influence of an...

journal_title：Transplantation

authors： Neumann U,Puhl G,Bahra M,Berg T,Langrehr JM,Neuhaus R,Neuhaus P

更新日期：2006-07-15 00:00:00

abstract：BACKGROUND:The authors studied the relationship between the dynamics of Epstein-Barr virus (EBV) load, CD8 T-cell activation and differentiation, and EBV-associated symptoms in 25 children after kidney transplantation (Tx). METHODS:Twenty-two patients were enrolled at the time of Tx and three at diagnosis of EBV-induc...

journal_title：Transplantation

authors： Baudouin V,Dehée A,Pédron-Grossetete B,Ansart-Pirenne H,Haddad E,Maisin A,Loirat C,Sterkers G

更新日期：2004-06-15 00:00:00

abstract：BACKGROUND:At our institution, increased kidney donation from unrelated donors accounts for a steady rise in live donor kidney transplantation rates. We compared outcomes of living related (LRT) versus living unrelated kidney transplants (LURT) and analyzed the effect of early rejection upon graft survival. METHODS:A ...

journal_title：Transplantation

authors： Fuller TF,Feng S,Brennan TV,Tomlanovich S,Bostrom A,Freise CE

更新日期：2004-10-15 00:00:00

abstract：BACKGROUND:Apoptosis is a well-documented pathway for islet cell death. One potential mechanism is overexpression of death-promoting Bax compared with antiapoptotic Bcl-2 in islets. METHODS:We isolated islets from 10 human pancreata and measured the expression of Bax mRNA and Bcl-2 mRNA by real-time quantitative polym...

journal_title：Transplantation

authors： Thomas D,Yang H,Boffa DJ,Ding R,Sharma VK,Lagman M,Li B,Hering B,Mohanakumar T,Lakey J,Kapur S,Hancock WW,Suthanthiran M

更新日期：2002-12-15 00:00:00

abstract：BACKGROUND:Chronic renal allograft failure remains a major challenge to overcome. Factors such as donor quality, delayed graft function (DGF), acute rejection, and immunosuppression are known to affect long-term outcome, but their relationship to histological damage to graft outcome is unclear. METHODS:Protocol kidney...

journal_title：Transplantation

authors： Nankivell BJ,Fenton-Lee CA,Kuypers DR,Cheung E,Allen RD,O'Connell PJ,Chapman JR

更新日期：2001-02-27 00:00:00

abstract：:Considerable variations in the suppression of graft-versus-host disease with monoclonal anti-Thy-1 antibodies were found to relate to substantial differences noted in the expression of mouse Thy-1 marker on lymph node and spleen cells of Thy-1.1 (AKR/J, C57BL/6.Thy-1.1) and Thy 1.2 (AKR/Cu, C57BL/6) mice. Thy-1.1 mice...

journal_title：Transplantation

authors： Mysliwietz J,Thierfelder S,Hoffmann-Fezer G,Kummer U

更新日期：1990-04-01 00:00:00

abstract：:The majority of skin tumors induced in mice by ultraviolet (UV) light are rejected when implanted into normal syngeneic recipients. Subcarcinogenic levels of UV light exposure render the normally resistant mice susceptible to tumor challenge. The immunoregulatory effect of UV light appears to be additive, since the gr...

journal_title：Transplantation

authors： Daynes RA,Spellman CW,Woodward JG,Stewart DA

更新日期：1977-04-01 00:00:00

abstract：INTRODUCTION:Statins are an established therapy after cardiac transplantation. Sirolimus (Srl) has been used successfully in cardiac transplant patients. However, potential side effects are hyperlipidemia and interactions with statins. The aim of the study was to evaluate the safety and efficacy of statin therapy after...

journal_title：Transplantation

authors： Aliabadi AZ,Mahr S,Dunkler D,Grömmer M,Zimpfer D,Wolner E,Grimm M,Zuckermann AO

更新日期：2008-12-27 00:00:00

abstract：BACKGROUND:HLAMatchmaker is a computer algorithm that determines human leukocyte antigen (HLA) compatibility at the level of polymorphic amino acid triplets in antibody-accessible sequence positions. Recent studies have shown that HLA-DR-matched kidney transplant recipients with zero to two triplet mismatches had almos...

journal_title：Transplantation

authors： Duquesnoy RJ,Howe J,Takemoto S

更新日期：2003-03-27 00:00:00

abstract：:Diarrhea is a frequent but overlooked complication of kidney transplantation. Diarrhea is repeatedly neglected, often considered by patients and clinicians an unavoidable side effect of immunosuppressive regimens. It is, however, associated with a significant impairment in life quality. Severe and chronic posttranspla...

journal_title：Transplantation

authors： Aulagnon F,Scemla A,DeWolf S,Legendre C,Zuber J

更新日期：2014-10-27 00:00:00

abstract：BACKGROUND:Everolimus reduces the progression of cardiac allograft vasculopathy (CAV) in de novo heart transplant (HTx) recipients, but the influence on established CAV is unknown. METHODS:In this Nordic Certican Trial in Heart and lung Transplantation substudy, 111 maintenance HTx recipients (time post-HTx 5.8 ± 4.3 ...

journal_title：Transplantation

authors： Arora S,Ueland T,Wennerblom B,Sigurdadottir V,Eiskjær H,Bøtker HE,Ekmehag B,Jansson K,Mortensen SA,Saunamaki K,Simonsen S,Gude E,Bendz B,Solbu D,Aukrust P,Gullestad L

更新日期：2011-07-27 00:00:00

abstract：:The case studies of four patients with post-transplantation calcinosis are presented. Three of the four patients died of inanition and sepsis secondary to infection of extensive soft tissue ulcers and diffuse cutaneous vascular calcification with gangrene. The fourth patient survived following removal of all four para...

journal_title：Transplantation

authors： Perloff LJ,Spence RK,Grossman RA,Barker CF

更新日期：1979-01-01 00:00:00

abstract：:Two anti-H-2Ld sera were analyzed, BALB/c-H-2dm2 anti-BALB/cBy and (C3H X BALB/c-H-2dm2)F1 anti-BALB/cHe, the latter also containing anti-Qa antibodies. Their reaction patterns were compared with an anti-Qa serum (C3H X BALB/cBy)F1 anti-BALB/cHe. Four H-2 specificities could be detected by the anti-H-2Ld sera, two alr...

journal_title：Transplantation

authors： Oudshoorn-Snoek M,Iványi D,Démant P

更新日期：1981-08-01 00:00:00

abstract：:We have done a comparative analysis of two consecutive clinical trials at our center: the first in 56 patients who received blood transfusions from their prospective donors (DST group), and the second in 36 patients who received such transfusions while they were taking Imuran in an attempt to reduce the incidence of s...

journal_title：Transplantation

authors： Glass NR,Miller DT,Sollinger HW,Belzer FO

更新日期：1983-12-01 00:00:00

abstract：:Idarubicin was conjugated to anti-Ly-2.1 and anti-L3T4 monoclonal antibodies. These conjugates were used to investigate their effects on skin graft survival in mice. Several donor and recipient combinations were used so that the effect of individual or mixtures of conjugates on class I and class II antigenic differenc...

journal_title：Transplantation

authors： Smyth MJ,McKenzie IF,Pietersz GA

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Diarrhea is a frequent complication of solid organ transplantation. Cryptosporidiosis is classically reported in patients with acquired immunodeficiency syndrome and emerged as a cause of persistent diarrhea in solid organ transplant patients. METHODS:Through the ANOFEL Cryptosporidium National Network and ...

journal_title：Transplantation

authors： Lanternier F,Amazzough K,Favennec L,Mamzer-Bruneel MF,Abdoul H,Tourret J,Decramer S,Zuber J,Scemla A,Legendre C,Lortholary O,Bougnoux ME,ANOFEL Cryptosporidium National Network and Transplant Cryptosporidium Study Group.

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:The innovative pure laparoscopic living donor right hepatectomy (LLDRH) procedure for liver transplantation has never been fully compared to open living donor right hepatectomy (OLDRH). We aimed to compare the donor safety and graft results of pure LLDRH to those of OLDRH. METHODS:From May 2013 to July 2017...

journal_title：Transplantation

authors： Park J,Kwon DCH,Choi GS,Kim SJ,Lee SK,Kim JM,Lee KW,Chung YJ,Kim KS,Lee JS,Rhu J,Kim GS,Gwak MS,Ko JS,Lee JE,Lee S,Joh JW

更新日期：2019-10-01 00:00:00

abstract：:A new case of anti-factor V inhibitor is described in a 46-year-old man, who received a liver transplantation for hepatocellular carcinoma, without exposure to bovine thrombin or fibrin glue during the operative course. The inhibition occurred on the 14th postoperative day, while the patient was being treated with oxa...

journal_title：Transplantation

authors： Leroy-Matheron C,Mallat A,Duvoux C,Métreau JM,Cherqui D,Dhumeaux D,Gouault-Heilmann M

更新日期：1999-10-15 00:00:00

abstract：:Rat recipients of renal allografts and unilaterally nephrectomized control rats were studied to evaluate the response in blood pressure to prednisolone in diverse doses, and to determine the dosage required to achieve adequate immunosuppression without undue complication of hypertension. While a continuous infusion of...

journal_title：Transplantation

authors： de Keijzer MH,Provoost AP,Van Aken M,Wolff ED,Molenaar JC

更新日期：1987-03-01 00:00:00

abstract：:To characterize further lymphomas which arise in chronically immunosuppressed allotransplant patients, we studied the clinical and histological features of seven cases of nonHodgkin's lymphoma and determined the immunological phenotype in four cases, which developed in a series of 182 patients who underwent cardiac tr...

journal_title：Transplantation

authors： Weintraub J,Warnke RA

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:Plasma level of plasminogen activator inhibitor (PAI)-1 is genetically determined by a polymorphism in the promoter region, involving two alleles, 4G and 5G. Plasma PAI-1 concentrations are higher in subjects homozygous for the 4G allele than other genotypes (5G/5G and 4G/5G). Such genetic variation in fibri...

journal_title：Transplantation

authors： Chow KM,Szeto CC,Szeto CY,Poon P,Lai FM,Li PK

更新日期：2002-12-27 00:00:00

abstract：BACKGROUND:Recent insights suggest that endothelial cell (EC) activation plays a major role in renal ischemia-reperfusion (I/R) injury. Interactions between ECs and pericytes via signaling molecules, including angiopoietins, are involved in maintenance of the vascular integrity. Experimental data have shown that enhanc...

journal_title：Transplantation

authors： de Vries DK,Khairoun M,Lindeman JH,Bajema IM,de Heer E,Roest M,van Zonneveld AJ,van Kooten C,Rabelink TJ,Schaapherder AF,Reinders ME

更新日期：2013-08-15 00:00:00