Abstract:
BACKGROUND:The Centers for Disease Control and Prevention (CDC) initiated the Colorectal Cancer Screening Demonstration Program (CRCSDP) to explore the feasibility of establishing a large-scale colorectal cancer screening program for underserved populations in the United States. The authors of the current report provide a detailed description of the total program costs (clinical and nonclinical) incurred during both the start-up and service delivery (screening) phases of the 4-year program. METHODS:Tailored cost questionnaires were completed by staff at the 5 CRCSDP sites. Cost data were collected for clinical services and nonclinical programmatic activities (program management, data collection, and tracking, etc). In-kind contributions also were measured and were assigned monetary values. RESULTS:Nearly $11.3 million was expended by the 5 sites over 4 years, and 71% was provided by the CDC. The proportion of funding spent on clinical service delivery and service delivery/patient support comprised the largest proportion of cost during the implementation phase (years 2-4). The per-person nonclinical cost comprised a substantial portion of total costs for all sites. The cost per person screened varied across the 5 sites and by screening method. Overall, economies of scale were observed, with lower costs resulting from larger numbers of individuals screened. CONCLUSIONS:Programs incur substantial variable costs related to clinical services and semivariable costs related to nonclinical services. Therefore, programs that serve large populations are likely to achieve a lower cost per person.
journal_name
Cancerjournal_title
Cancerauthors
Subramanian S,Tangka FK,Hoover S,Beebe MC,DeGroff A,Royalty J,Seeff LCdoi
10.1002/cncr.28158subject
Has Abstractpub_date
2013-08-01 00:00:00pages
2855-62eissn
0008-543Xissn
1097-0142journal_volume
119 Suppl 15pub_type
杂志文章,多中心研究相关文献
CANCER文献大全abstract:INTRODUCTION:The presence of nodal metastases remains the most significant predictive factor for regional recurrence and survival in patients treated for squamous cell carcinoma of the head and neck. Survival rates are further decreased in patients with nodal metastases that have spread beyond the lymph node capsule, o...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20011215)92:12<3030::aid-cncr101
更新日期:2001-12-15 00:00:00
abstract::Review of 61 surgically resected small hepatocellular carcinomas (HCC) less than or equal to 3 cm in diameter yielded a simple gross classification system of five types based on tumor shape, which is highly correlated with microscopic and clinical features, including prognosis. Type 1 (single nodular type) tumors (n =...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870815)60:4<810::aid-cncr28206
更新日期:1987-08-15 00:00:00
abstract:BACKGROUND:Sialyl-Tn (STn) represents an aberrantly glycosylated mucin epitope that is expressed in breast carcinoma and other adenocarcinomas and is an important factor in the development of novel immunotherapeutic approaches. The primary aim of the current study was to investigate the influence of STn expression on t...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/(sici)1097-0142(19971215)80:12<2240::aid-c
更新日期:1997-12-15 00:00:00
abstract::A growing body of research shows that a majority of patients with cancer report having religious and spiritual (R/S) beliefs, engaging in R/S behaviors, or deriving comfort from R/S experiences. These studies have been reviewed but not subjected to rigorous critical analysis. A meta-analytic approach is needed to prov...
journal_title:Cancer
pub_type: 杂志文章,meta分析
doi:10.1002/cncr.29349
更新日期:2015-11-01 00:00:00
abstract::Management of testis cancer in children differs from that in adults due to the histological types and varying tolerances to chemotherapy agents. Embryonal adrenocarcinoma (endodermal sinus tumor, Teilum's tumor) is a tumor of infancy and young children and less aggressive than other testis cancers. Most cases require ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.1980.45.s7.1803
更新日期:1980-04-01 00:00:00
abstract:BACKGROUND:The importance of the bone marrow microenvironment in multiple myeloma is receiving increasing attention. Recent studies have suggested the importance of cytokine production and cell-cell contact by bone marrow stromal cells in the survival of myeloma cells. METHODS:In the current study, the authors examine...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20010401)91:7<1219::aid-cncr1122
更新日期:2001-04-01 00:00:00
abstract:BACKGROUND:The development of novel therapeutic approaches for cancer therapy is important, especially for tumors that have poor response or develop resistance to standard chemotherapy and radiation. We discovered that noninvasive radiofrequency (RF) fields can affect cancer cells but not normal cells, inhibit progress...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.28895
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:There is limited published evidence regarding the efficacy of total skin electron beam radiation for patients with the diffuse erythrodermic form of mycosis fungoides. METHODS:Forty-five patients with erythrodermic mycosis fungoides were managed at McMaster University in Hamilton, Ontario, Canada (n=34), an...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-0142(19990501)85:9<1985::aid-cn
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:Cytotoxic analogs of somatostatin (SST), such as AN-238, which consists of 2-pyrrolinodoxorubicin (AN-201) linked to the SST carrier RC-121, can be targeted to tumors that express SST receptors. Because SST receptors are present in ovarian carcinoma cells, the authors evaluated the effect of AN-238 on the UC...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20010901)92:5<1168::aid-cncr1435
更新日期:2001-09-01 00:00:00
abstract:BACKGROUND:The distinction of sporadic from inherited medullary thyroid carcinomas (MTCs) is of clinical importance because of the differences in prognosis, and the need for family screening for genetic counseling required in the latter. Germline mutations in the RET protooncogene are associated with multiple endocrine...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19950801)76:3<479::aid-cncr28207
更新日期:1995-08-01 00:00:00
abstract::Nine children with acute promyelocytic leukemia (APL) are presented. This series of children represents 7% of all acute leukemias and 21% of acute myelogenous leukemias seen during the same period at the Red Cross War Memorial Children's Hospital. These figures are much higher than the incidence quoted in other series...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870301)59:5<933::aid-cncr28205
更新日期:1987-03-01 00:00:00
abstract::A prospective study was carried out on 22 patients to assess the diagnostic ability to stage renal cell carcinoma by computed tomography, dynamic computed tomography, arteriography, ultrasonography, and radionuclide scanning. Dynamic computed tomography remedied the most consequential diagnostic shortcomings of conven...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19841115)54:10<2205::aid-cncr282
更新日期:1984-11-15 00:00:00
abstract::Fifty patients with non resectable and/or inoperable bronchogenic carcinoma were entered into a feasibility study of cisplatin (CDDP) given in continuous infusion with concurrent radiation therapy. The radiation therapy regimen consisted of 2 Gy given 5 days a week in the first 3 and last 2 weeks of a 7-week split cou...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910115)67:2<357::aid-cncr28206
更新日期:1991-01-15 00:00:00
abstract::Amyloid as defined by positive Congo red green birefringence and STB red birefringence was observed in the stroma of a tubular carcinoma of minor salivary gland origin. The amyloid exhibited additional histochemical characteristics of immunamyloid, viz., positive DMAB-nitrate and DC-reactions and spontaneous autofluor...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197805)41:5<1836::aid-cncr282041
更新日期:1978-05-01 00:00:00
abstract::Ovarian cancer disproportionately affects women 65 years of age and older who are likely to have concomitant changes in physical ability, physiological functioning, and other chronic conditions associated with advancing age. The National Institute on Aging, National Cancer Institute, and the American Cancer Society co...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.2820710204
更新日期:1993-01-15 00:00:00
abstract::To investigate the possible implications of heterogeneity among the non-Hodgkin's lymphomas for bone marrow purging using complement-fixing monoclonal antibodies to lymphoma-associated antigens, a panel of large cell lymphoma cell lines of diverse phenotypes was treated with monoclonal antibodies DLC-48 and LN-1. An a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19880315)61:6<1082::aid-cncr2820
更新日期:1988-03-15 00:00:00
abstract::Two cases of primary non-Hodgkin's lymphomas of the breast were studied with light and electron microscopy. By light microscopy, according to Rappaport's classification, one was a poorly differentiated lymphocytic lymphoma, the other a diffuse histiocytic lymphoma. However, the ultrastructural features of the latter w...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197705)39:5<2025::aid-cncr282039
更新日期:1977-05-01 00:00:00
abstract:BACKGROUND:It is well established that prenatal biologic processes are important for the development of some childhood cancers, whereas less is known regarding their influence on adult cancer risk. High birth weight has been associated with risk of breast cancer, whereas studies of other specific cancers and all cancer...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22773
更新日期:2007-07-15 00:00:00
abstract::Aziridinylbenzoquinone (AZQ) was studied in a Phase II protocol for persons with glioma of the central nervous system (CNS) recurrent or progressive after surgery and radiotherapy. Patients received AZQ, 30 mg/m2 intravenously every 3 weeks if previously untreated or 27.5 mg/m2 if previously exposed to cytotoxic drugs...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850915)56:6<1311::aid-cncr2820
更新日期:1985-09-15 00:00:00
abstract:BACKGROUND:Squamous cell lung carcinoma (SLC), the most frequent type of lung cancer, generally is treated surgically and its prognosis is poor. The only current clinically useful prognostic criterion is lymph node staging (TNM classification). Expression of a novel tumor-associated carbohydrate epitope Gal beta 1-3[Fu...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19921001)70:7<1867::aid-cncr2820
更新日期:1992-10-01 00:00:00
abstract::This report documents, in seven infants younger than 2 years of age, a previously unrecognized association of a renal embryonal neoplasm (malignant rhabdoid tumor in six patients and a Wilms' tumor in one) with an embryonal primary tumor originating in the central nervous system. The neuroepithelial tumors included th...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19841115)54:10<2137::aid-cncr282
更新日期:1984-11-15 00:00:00
abstract:BACKGROUND:Two-thirds of cancer cases are associated with two lifestyle practices: 35% with the typical American diet, and 30% with tobacco use. In contrast to the field of tobacco control, research and resources dedicated to the field of nutrition have been limited, in part because dietary change has been considered c...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19930801)72:3+<1005::aid-cncr282
更新日期:1993-08-01 00:00:00
abstract:BACKGROUND:Because the prostatic capsule is often indistinct, recognition of extraprostatic extension by carcinoma depends heavily on the identification of carcinoma cells in the periprostatic adipose tissue. However, the distribution of adipose tissue along the prostatic surfaces has not been studied extensively. MET...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11231
更新日期:2003-04-01 00:00:00
abstract::Although progress has been made in providing cancer prevention and control services to the population, there remain sizeable segments of the population that are either uninvolved or underinvolved with national and state efforts. One method of reaching most of the population, including those segments currently not invo...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19930801)72:3+<1138::aid-cncr282
更新日期:1993-08-01 00:00:00
abstract:BACKGROUND:Interleukin-2 (IL-2) has immunomodulatory effects, including stimulating the activity of cytotoxic T cells and natural killer cells, and inducing the generation of lymphokine-activated killer cells. The authors investigated whether IL-2 may improve the duration of complete remission (CR) and survival in acut...
journal_title:Cancer
pub_type: 临床试验,杂志文章,评审
doi:
更新日期:1999-04-01 00:00:00
abstract::During the past decade, one of the major changes in the field of oncology has been in the surgical approach to primary and secondary cancer of the liver. As a result of data and experience gained in liver transplantation programs and with the application of vascular surgical principles, resectability rates have been i...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810501)47:9<2162::aid-cncr2820
更新日期:1981-05-01 00:00:00
abstract:BACKGROUND:Clinical practice guidelines for the management of breast carcinoma were introduced in Australia in October, 1995. This article describes the management of early-stage breast carcinoma both before and after the introduction of these guidelines. METHODS:All cases of early breast carcinoma that were diagnosed...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.20401
更新日期:2004-08-01 00:00:00
abstract::In this study of 2092 women with cancer of the breast, those who had practiced breast self-examination (BSE) had earlier cancer than did those who had not practiced BSE. This was true for both black and white races, all educational and economic levels, each age group, and within each period of delay between first symp...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810301)47:5<989::aid-cncr28204
更新日期:1981-03-01 00:00:00
abstract:BACKGROUND:Ewing sarcoma family of tumors (ESFT) of bone is extremely rare in Japan. The objectives of the current study were to assess the clinical outcome and prognostic factors of patients with ESFT of bone in Japan and to compare them between Euro-American and Japanese populations. METHODS:The authors conducted a ...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.22481
更新日期:2007-02-15 00:00:00
abstract::A 42-year-old man was admitted to the Cancer Division of the American MedicalCenter in February, 1956. He had been treated for erythrocytosis beginning 6 months previously, with reduction of his hemoglobin to relatively normal values. On admission, a huge tumor of the left kidney was palable. Roentgenograms of the ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197506)35:6<1701::aid-cncr282035
更新日期:1975-06-01 00:00:00