A RASH analysis of National Toxicology Program data: predictions for 30 compounds to be tested in rodent carcinogenesis experiments.

abstract：:The historical exposures to aromatic amines of various occupational groups are briefly reviewed. Modern studies indicate that other occupational groups might have risks worth investigating; these include machinists and workers in the chemical industry. Details of a recent investigation into the exposure of dye workers...

journal_title：Environmental health perspectives

authors： Cartwright RA

更新日期：1983-03-01 00:00:00

abstract：:Laboratory animal diets for studies to determine the endocrine-disrupting potential of chemicals are under scrutiny because they can affect both assay control values and assay sensitivity. Although phytoestrogen content is important, we have previously shown that a phytoestrogen-rich diet and a phytoestrogen-free diet...

journal_title：Environmental health perspectives

authors： Odum J,Tinwell H,Tobin G,Ashby J

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Perfluoroalkyl substances (PFAS) may affect body mass index (BMI) and other components of cardiometabolic (CM) risk during childhood, but evidence is scarce and inconsistent. OBJECTIVES:We estimated associations between prenatal PFAS exposures and outcomes relevant to cardiometabolic risk, including a compo...

journal_title：Environmental health perspectives

authors： Manzano-Salgado CB,Casas M,Lopez-Espinosa MJ,Ballester F,Iñiguez C,Martinez D,Romaguera D,Fernández-Barrés S,Santa-Marina L,Basterretxea M,Schettgen T,Valvi D,Vioque J,Sunyer J,Vrijheid M

更新日期：2017-09-20 00:00:00

abstract：:The Environmental Public Health Tracking Network (EPHTN) proposes to link environmental hazards and exposures to health outcomes. Statistical methods used in case-control and cohort studies to link health outcomes to individual exposure estimates are well developed. However, reliable exposure estimates for many contam...

journal_title：Environmental health perspectives

authors： Mather FJ,White LE,Langlois EC,Shorter CF,Swalm CM,Shaffer JG,Hartley WR

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Epidemiologic studies have demonstrated that occupational noise exposure is associated with hypertension, but the related mechanism in vascular structural changes is unclear. OBJECTIVE:This panel study aimed to investigate effects of occupational noise exposure on ambulatory vascular structural properties i...

journal_title：Environmental health perspectives

authors： Chang TY,Su TC,Lin SY,Jain RM,Chan CC

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:We reviewed the scientific background for the current health-based World Health Organization (WHO) guideline value for manganese in drinking water. DATA SOURCES AND EXTRACTION:The initial starting point was the background document for the development of the WHO's guideline value for manganese in drinking wat...

journal_title：Environmental health perspectives

authors： Ljung K,Vahter M

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:Daily adult human exposure to bisphenol A (BPA) has been estimated at <1 µg/kg, with virtually complete first-pass conjugation in the liver in primates but not in mice. We measured unconjugated and conjugated BPA levels in serum from adult female rhesus monkeys and adult female mice after oral administration ...

journal_title：Environmental health perspectives

authors： Taylor JA,Vom Saal FS,Welshons WV,Drury B,Rottinghaus G,Hunt PA,Toutain PL,Laffont CM,VandeVoort CA

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Cadmium is a commonly occurring toxic food contaminant, but health consequences of early-life exposure are poorly understood. OBJECTIVES:We evaluated the associations between cadmium exposure and neurobehavioral development in preschool children. METHODS:In our population-based mother-child cohort study in...

journal_title：Environmental health perspectives

authors： Kippler M,Tofail F,Hamadani JD,Gardner RM,Grantham-McGregor SM,Bottai M,Vahter M

更新日期：2012-10-01 00:00:00

abstract：:Possible effects of Chernobyl fallout on outcome of pregnancy in Finland were evaluated in a nationwide follow-up study. The outcomes were the rate of live births and stillbirths, pregnancy loss, and induced abortions by municipality. Exposure was assessed based on nationwide surveys of radiation dose rate from the Ch...

journal_title：Environmental health perspectives

authors： Auvinen A,Vahteristo M,Arvela H,Suomela M,Rahola T,Hakama M,Rytömaa T

更新日期：2001-02-01 00:00:00

abstract：:Spatial epidemiology is the description and analysis of geographic variations in disease with respect to demographic, environmental, behavioral, socioeconomic, genetic, and infectious risk factors. We focus on small-area analyses, encompassing disease mapping, geographic correlation studies, disease clusters, and clus...

journal_title：Environmental health perspectives

authors： Elliott P,Wartenberg D

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:"Airwave" is the new communication system currently being rolled out across the United Kingdom for the police and emergency services, based on the Terrestrial Trunked Radio Telecommunications System (TETRA). Some police officers have complained about skin rashes, nausea, headaches, and depression as a conseq...

journal_title：Environmental health perspectives

authors： Wallace D,Eltiti S,Ridgewell A,Garner K,Russo R,Sepulveda F,Walker S,Quinlan T,Dudley S,Maung S,Deeble R,Fox E

更新日期：2010-06-01 00:00:00

abstract：:Spontaneous fetal death has been observed among various mammalian species after exposure to polychlorinated biphenyls (PCBs). Our exposure-based cohort study assessed the relationship between consumption of PCB-contaminated Lake Ontario sport fish and spontaneous fetal death using 1820 multigravid fertile women from t...

journal_title：Environmental health perspectives

authors： Mendola P,Buck GM,Vena JE,Zielezny M,Sever LE

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Discoveries that emerging and re-emerging pathogens have their origin in environmental change has created an urgent need to understand how these environmental changes impact disease burden. In this article we present a framework that provides a context from which to examine the relationship between environme...

journal_title：Environmental health perspectives

authors： Eisenberg JN,Desai MA,Levy K,Bates SJ,Liang S,Naumoff K,Scott JC

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Microcystin-producing Microcystis bloom is a severe water problem in the world. Some reports indicate that chronic exposure to microcystin may result in liver damage in adults, but information on effects in children is limited. OBJECTIVE:We investigated the relationship between microcystin exposure and live...

journal_title：Environmental health perspectives

authors： Li Y,Chen JA,Zhao Q,Pu C,Qiu Z,Zhang R,Shu W

更新日期：2011-10-01 00:00:00

abstract：:The dose-response relationship of the benzene covalent interaction with biological macromolecules from rat organs was studied. The administered dose range was 3.6 x 10(7) starting from the highest dosage employed, 486 mg/kg, which is oncogenic for rodents, and included low and very low dosages. The present study was i...

journal_title：Environmental health perspectives

authors： Mazzullo M,Bartoli S,Bonora B,Colacci A,Grilli S,Lattanzi G,Niero A,Turina MP,Parodi S

更新日期：1989-07-01 00:00:00

abstract：:The purpose of this study was to examine whether perinatal exposure to two major environmental endocrine-disrupting chemicals, bisphenol A (BPA; 0.1 mg/kg/day orally) and nonylphenol [NP; 0.1 mg/kg/day (low dose) and 10 mg/kg/day (high dose) orally] daily from gestational day 3 to postnatal day 20 (transplacental and ...

journal_title：Environmental health perspectives

authors： Negishi T,Kawasaki K,Suzaki S,Maeda H,Ishii Y,Kyuwa S,Kuroda Y,Yoshikawa Y

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Although indoor residual spraying (IRS) with dichlorodiphenyltrichloroethane (DDT) and pyrethroids effectively controls malaria, it potentially increases human exposure to these insecticides. Previous studies suggest that prenatal exposure to these insecticides may impact human neurodevelopment. OBJECTIVES:...

journal_title：Environmental health perspectives

authors： Eskenazi B,An S,Rauch SA,Coker ES,Maphula A,Obida M,Crause M,Kogut KR,Bornman R,Chevrier J

更新日期：2018-04-06 00:00:00

abstract：:There is a significant public health concern about the potential effects of occupational exposure to toxic substances on reproductive outcomes. Several toxicants with reported reproductive and developmental effects are still in regular commercial or therapeutic use and thus present potential exposure to workers. Examp...

journal_title：Environmental health perspectives

authors： Lawson CC,Schnorr TM,Daston GP,Grajewski B,Marcus M,McDiarmid M,Murono E,Perreault SD,Schrader SM,Shelby M

更新日期：2003-04-01 00:00:00

abstract：:The importance of urban dust as a source of lead for young children is still disputed. Although blood-lead data from various population surveys usually show a peak concentration in early childhood, there is evidence that such a peak is small or absent altogether in children without much access to the general environme...

journal_title：Environmental health perspectives

authors： Duggan MJ

更新日期：1983-04-01 00:00:00

abstract：:Once a sign of modernization and growth, dams are often seen today as symbols of environmental and social devastation. Over 800,000 dams have been built worldwide to provide drinking water, flood control, hydropower, irrigation, navigation, and water storage. Dams do indeed provide these things,but at the cost of seve...

journal_title：Environmental health perspectives

authors： Joyce S

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:The 1974 Safe Drinking Water Act (SDWA) regulates >170,000 public water systems to protect health, but not >13 million private wells. State and local government requirements for private well water testing are rare and inconsistent; the responsibility to ensure water safety remains with individual households....

journal_title：Environmental health perspectives

authors： Zheng Y,Flanagan SV

更新日期：2017-08-03 00:00:00

abstract：:We describe the successes and challenges faced by federal and local government agencies in the United States as they have attempted in recent years to connect public and environmental health, housing, community development, and building design with environmental, housing, and building laws, codes, and policies. These ...

journal_title：Environmental health perspectives

authors： Jacobs DE,Kelly T,Sobolewski J

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Although it is well established that air pollutants can exacerbate asthma, the link with new asthma onset in children is less clear. OBJECTIVE:We assessed the association between the onset of childhood asthma with both time of birth and time-varying exposures to outdoor air pollutants. METHOD:An open cohor...

journal_title：Environmental health perspectives

authors： Tétreault LF,Doucet M,Gamache P,Fournier M,Brand A,Kosatsky T,Smargiassi A

更新日期：2016-08-01 00:00:00

abstract：:The metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), the most abundant compound of the aminoimidazoazaarens (AIA) group of mutagens/carcinogens isolated from the crust of fried and broiled meat, was examined in freshly isolated hepatocytes from untreated rat, mouse, hamster, and guinea pig. Activa...

journal_title：Environmental health perspectives

authors： Alexander J,Fossum BH,Holme JA

更新日期：1994-10-01 00:00:00

abstract：:Sulfur trioxide in the exhaust gas of an internal combustion engine is removed and concentrated by absorption in a solution of 80% isopropyl alcohol, which quantitatively absorbs it and inhibits the oxidation of any sulfur dioxide which may be absorbed. The absorbed sulfur trioxide (sulfuric acid) is determined by an ...

journal_title：Environmental health perspectives

authors： Arnold DR

更新日期：1975-04-01 00:00:00

abstract：:The neurochemical basis of memory has been approached experimentally in four different ways: the bioassay; the interventive approach; the interventive-correlative approach; and the correlative approach. These approaches are fundamentally similar to those used for the study of the chemistry of any behavior. Each of the...

journal_title：Environmental health perspectives

authors： Dunn AJ

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:Epidemiologic and experimental studies have reported a variety of health effects in response to ozone (O3) exposure, and some have indicated that certain populations may be at increased or decreased risk of O3-related health effects. OBJECTIVES:We sought to identify potential response-modifying factors to d...

journal_title：Environmental health perspectives

authors： Vinikoor-Imler LC,Owens EO,Nichols JL,Ross M,Brown JS,Sacks JD

更新日期：2014-11-01 00:00:00

abstract：:Previous NIOSH studies demonstrated the embryo- and fetotoxicity and teratogenicity of ethylene glycol monoethyl ether (EGEE) applied to the shaved skin of pregnant rats. In the present study ethylene glycol monoethyl ether acetate (EGEEA), ethylene glycol monobutyl ether (EGBE), and diethylene glycol monoethyl ether ...

journal_title：Environmental health perspectives

authors： Hardin BD,Goad PT,Burg JR

更新日期：1984-08-01 00:00:00

abstract：:In most neurotoxicological studies morphological assessment focuses on pathological effects, like degenerative changes in neuronal perikarya, axonopathy, demyelination, and glial and endothelial cell reactions. Similarly, the assessment of physiological and behavioral effects center on evident neurological symptoms, l...

journal_title：Environmental health perspectives

authors： Altman J

更新日期：1987-10-01 00:00:00

abstract：:We used the case-crossover design to identify any increase in mortality in Seoul, Korea, when there were higher levels of ambient air pollution on case-days than would be expected solely as a result of chance. This empirical study showed that either unidirectional retrospective (selecting only control days prior to de...

journal_title：Environmental health perspectives

authors： Lee JT,Schwartz J

更新日期：1999-08-01 00:00:00